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Monday, August 4, 2014

Former Anti-GMO Activist Says Science Changed His Mind

Former Anti-GMO Activist Says Science Changed His Mind


 

For years, British environmental activist Mark Lynas destroyed genetically modified food (GMO) crops in what he calls a successful campaign to force the business of agriculture to be more holistic and ecological in its practices.

His targets were companies like Monsanto and Syngenta — leaders in developing genetically modified crops.

Earlier this month he went in front of the world to reverse his position on GMOs.

At the Oxford Farming Conference in Britain, Lynas apologized for helping "to start the anti-GMO movement" and told his former allies to "get out of the way, and let the rest of us get on with feeding the world sustainably."

He spoke to Jacki Lyden, host of weekends on All Things Considered, about his change of heart.

Interview Highlights

On 'discovering science'
"When I started off as an anti-GMO activist, it was very much an ideological position. I was scared of the new technology, you know, it just seemed to be messing with the basic building blocks of life. But what happened in the sort of 10, 15 years since then, is that I have written a couple of books on climate change, and I really fell in love with the scientific method as a way of establishing knowledge about the world. It eventually dawned on me ... that I was actually being anti-science in the way I was talking about GMOs, and that there are many ways a stronger scientific consensus on the safety of GMOs than there is about the reality of climate change."

On the 'saga of golden rice'

"One of the case studies that really changed my mind about this was the saga of golden rice, which was developed to be vitamin A-enhanced, because something like a quarter million children per year die from a vitamin A deficiencies in developing countries, particularly in South Asia ... Greenpeace has been waging a campaign to stop this rice from ever being developed ... You can make a pretty strong case that tens of thousands of children have died because they were denied access to this purely because it's GM, and there is a ideological bias against that."

On admitting fallibility

"I would be the first one to say that having been wrong before, I am not infallible now. For me, it's important to look at what the mainstream science is saying. We need to get on with developing more biotech crops because they can potentially be an enormous boon environmentally, and I think that is a message that has been lost in this debate so far."

Self-assembling anti-cancer molecules created in minutes

 
Self-assembling anti-cancer molecules created in minutes       
Professor Peter Scott of the University of Warwick. Credit: University of Warwick
Researchers have developed a simple and versatile method for making artificial anti-cancer molecules that mimic the properties of one of the body's natural defence systems.

The chemists, led by Professor Peter Scott at the University of Warwick, UK, have been able to produce molecules that have a similar structure to peptides which are naturally produced in the body to fight cancer and infection.

Published in Nature Chemistry, the molecules produced in the research have proved effective against in laboratory tests, in collaboration with Roger Phillips at the Institute for Cancer Therapeutics, Bradford, UK.

Artificial peptides had previously been difficult and prohibitively expensive to manufacture in large quantities, but the new process takes only minutes and does not require costly equipment. Also, traditional peptides that are administered as drugs are quickly neutralised by the body's biochemical defences before they can do their job.

A form of complex chemical self-assembly, the new method developed at Warwick addresses these problems by being both practical and producing very stable molecules. The new peptide mimics, called triplexes, have a similar 3D helix form to natural peptides.
"The chemistry involved is like throwing Lego blocks into a bag, giving them a shake, and finding that you made a model of the Death Star" says Professor Scott. "The design to achieve that takes some thought and computing power, but once you've worked it out the method can be used to make a lot of complicated molecular objects."

Describing the self-assembly process behind the artificial peptides Professor Scott says: "When the organic chemicals involved, an amino alcohol derivative and a picoline, are mixed with iron chloride in a solvent, such as water or methanol, they form strong bonds and are designed to naturally fold together in minutes to form a helix. It's all thermodynamically downhill. The assembly instructions are encoded in the chemicals themselves."

"Once the solvent has been removed we are left with the peptide mimics in the form of crystals", says Professor Scott. "There are no complicated separations to do, and unlike a Lego model kit there are no mysterious bits left over. In practical terms, the chemistry is pretty conventional. The beauty is that these big molecules assemble themselves. Nature uses this kind of self-assembly to make complex asymmetric like proteins all the time, but doing it artificially is a major challenge."

Whilst the peptide mimics created by the process have been successful in on colon they will require further research before they can be used in clinical trials on patients. Nevertheless they are made of simple building blocks and in early tests the team have shown that they have very low toxicity to bacteria. "This is very unusual and promising selectivity," says Professor Scott.
Explore further: Computer simulations help design molecules with potential as a cancer therapy
More information: Asymmetric triplex metallohelices with high and selective activity against cancer cells, Nature Chemistry, DOI: 10.1038/nchem.2024
Journal reference: Nature Chemistry

Read more at: http://phys.org/news/2014-08-self-assembling-anti-cancer-molecules-minutes.html#jCp

Gallium arsenide

Gallium arsenide

Condensed from Wikipedia, the free encyclopedia
 
Gallium arsenide
Samples of gallium arsenide
Gallium arsenide crystal.jpg
Identifiers
CAS number1303-00-0 YesY
PubChem14770
ChemSpider14087 YesY
EC number215-114-8
UN number1557
MeSHgallium+arsenide
RTECS numberLW8800000
Jmol-3D imagesImage 1
Properties
Molecular formulaGaAs
Molar mass144.645 g/mol
AppearanceVery dark red, vitreous crystals
Odorgarlic-like when moistened
Density5.3176 g/cm3
Melting point1,238 °C (2,260 °F; 1,511 K)
Solubility in waterinsoluble
Solubilitysoluble in HCL
insoluble in ethanol, methanol, acetone
Band gap1.424 eV (at 300 K)
Electron mobility8500 cm2/(V·s) (at 300 K)
Thermal conductivity0.55 W/(cm·K) (at 300 K)
Refractive index (nD)3.8[1]
Structure
Crystal structureZinc blende
Space groupT2d-F-43m
Lattice constanta = 565.35 pm
Coordination
geometry
Tetrahedral
Molecular shapeLinear
Hazards
MSDSExternal MSDS
GHS pictogramsThe skull-and-crossbones pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) The environment pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS)
GHS hazard statementsH301, H331, H410
GHS precautionary statementsP261, P273, P301+310, P311, P501
EU classificationToxic T Dangerous for the Environment (Nature) N
R-phrasesR23/25, R50/53
S-phrases(S1/2), S20/21, S28, S45, S60, S61
NFPA 704
Flammability code 1: Must be pre-heated before ignition can occur. Flash point over 93 °C (200 °F). E.g., canola oil Health code 3: Short exposure could cause serious temporary or residual injury. E.g., chlorine gas Reactivity code 2: Undergoes violent chemical change at elevated temperatures and pressures, reacts violently with water, or may form explosive mixtures with water. E.g., phosphorus Special hazard W: Reacts with water in an unusual or dangerous manner. E.g., cesium, sodiumNFPA 704 four-colored diamond
1
3
2
W
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references
Gallium arsenide (GaAs) is a compound of the elements gallium and arsenic. It is a III-V direct bandgap semiconductor with a zinc blende crystal structure. Gallium arsenide is used in the manufacture of devices such as microwave frequency integrated circuits, monolithic microwave integrated circuits, infrared light-emitting diodes, laser diodes, solar cells and optical windows.[2]
GaAs is often used as a substrate material for the epitaxial growth of other III-V semiconductors including: Indium gallium arsenide, aluminum gallium arsenide and others.

Preparation and chemistry

In the compound, gallium has a +3 oxidation state. Gallium arsenide single crystals can be prepared by three industrial processes:[2]
  • The vertical gradient freeze (VGF) process. Most GaAs wafers are produced using this process.[3]
  • Crystal growth using a horizontal zone furnace in the Bridgman-Stockbarger technique, in which gallium and arsenic vapors react, and free molecules deposit on a seed crystal at the cooler end of the furnace.
  • Liquid encapsulated Czochralski (LEC) growth is used for producing high-purity single crystals that can exhibit semi-insulating characteristics (see below).
Alternative methods for producing films of GaAs include:[2][4]
2 Ga + 2 AsCl
3
→ 2 GaAs + 3 Cl
2
Ga(CH
3
)
3
+ AsH
3
→ GaAs + 3 CH
4
4 Ga + As
4
→ 4 GaAs
or
2 Ga + As
2
→ 2 GaAs
Oxidation of GaAs occurs in air and degrades performance of the semiconductor. The surface can be passivated by depositing a cubic gallium(II) sulfide layer using a tert-butyl gallium sulfide compound such as (tBuGaS)
7
.[5]
A pristine 2-inch single crystal gallium arsenide wafer with a (100) surface orientation. Purple features are a reflection of a nitrile glove.

Semi-insulating crystals

If a GaAs boule is grown with excess arsenic present, it gets certain defects, in particular arsenic antisite defects (an arsenic atom at a gallium atom site within the crystal lattice). The electronic properties of these defects (interacting with others) cause the Fermi level to be pinned to near the center of the bandgap, so that this GaAs crystal has very low concentration of electrons and holes.
This low carrier concentration is similar to an intrinsic (perfectly undoped) crystal, but much easier to achieve in practice. These crystals are called "semi-insulating", reflecting their high resistivity of 107–109 Ω·cm (which is quite high for a semiconductor, but still much lower than a true insulator like glass).[6]

Etching

Wet etching of GaAs industrially uses an oxidizing agent such as hydrogen peroxide or bromine water,[7] and the same strategy has been described in a patent relating to processing scrap components containing GaAs where the Ga3+ is complexed with a hydroxamic acid ("HA"), for example:[8]
GaAs + H
2
O
2
+ "HA" → "GaA" complex + H
3
AsO
4
+ 4 H
2
O
This reaction produces arsenic acid.

Comparison with silicon

GaAs advantages

Some electronic properties of gallium arsenide are superior to those of silicon. It has a higher saturated electron velocity and higher electron mobility, allowing gallium arsenide transistors to function at frequencies in excess of 250 GHz. Unlike silicon junctions, GaAs devices are relatively insensitive to heat owing to their wider bandgap. Also, GaAs devices tend to have less noise than silicon devices, especially at high frequencies. This is a result of higher carrier mobilities and lower resistive device parasitics. These properties recommend GaAs circuitry in mobile phones, satellite communications, microwave point-to-point links and higher frequency radar systems. It is used in the manufacture of Gunn diodes for generation of microwaves.

Another advantage of GaAs is that it has a direct band gap, which means that it can be used to absorb and emit light efficiently. Silicon has an indirect bandgap and so is relatively poor at emitting light. Nonetheless, advances silicon LEDs and lasers may be possible.

As a wide direct band gap material with resulting resistance to radiation damage, GaAs is an excellent material for space electronics and optical windows in high power applications.

Because of its wide bandgap, pure GaAs is highly resistive. Combined with the high dielectric constant, this property makes GaAs a very good electrical substrate and unlike Si provides natural isolation between devices and circuits. This has made it an ideal material for microwave and millimeter wave integrated circuits, MMICs, where active and essential passive components can readily be produced on a single slice of GaAs.

One of the first GaAs microprocessors was developed in the early 1980s by the RCA corporation and was considered for the Star Wars program of the United States Department of Defense. Those processors were several times faster and several orders of magnitude more radiation hard than silicon counterparts, but they were rather expensive.[9] Other GaAs processors were implemented by the supercomputer vendors Cray Computer Corporation, Convex, and Alliant in an attempt to stay ahead of the ever-improving CMOS microprocessor. Cray eventually built one GaAs-based machine in the early 1990s, the Cray-3, but the effort was not adequately capitalized, and the company filed for bankruptcy in 1995.

Complex layered structures of gallium arsenide in combination with aluminium arsenide (AlAs) or the alloy AlxGa1-xAs can be grown using molecular beam epitaxy (MBE) or using metalorganic vapor phase epitaxy (MOVPE). Because GaAs and AlAs have almost the same lattice constant, the layers have very little induced strain, which allows them to be grown almost arbitrarily thick. This allows for extremely high performance high electron mobility, HEMT transistors and other quantum well devices.

Silicon advantages

Silicon has three major advantages over GaAs for integrated circuit manufacture. First, silicon is abundant and cheap to process. Si is highly abundant in the Earth's crust, in the form of silicate minerals. The economy of scale available to the silicon industry has also reduced the adoption of GaAs.

In addition, a Si crystal has an extremely stable structure mechanically and it can be grown to very large diameter boules and can be processed with very high yields. It is also a decent thermal conductor, thus enabling very dense packing of transistors that need to get rid of their heat of operation, all very desirable for design and manufacturing of very large ICs. Such good mechanical characteristics also makes it a suitable material for the rapidly developing field of nanoelectronics.

The second major advantage of Si is the existence of a native oxide (silicon dioxide, SiO2), which is used as an insulator in electronic devices. Silicon dioxide can easily be incorporated onto silicon circuits, and such layers are adherent to the underlying Si. SiO2 is not only a good insulator (with a band gap of 8.9 eV), but the Si-SiO2 interface can be easily engineered to have excellent electrical properties, most importantly low density of interface states. GaAs does not have a native oxide and does not easily support a stable adherent insulating layer.[citation needed] Aluminum oxide (Al2O3) has been extensively studied as a possible gate oxide for GaAs (and InGaAs). However, at this point the electrical properties of the interfaces aren't comparable to those of the Si-SiO2 interface.

The third, advantage of silicon is that it possesses a higher hole mobility compared to GaAs (500 versus 400 cm2V-1s-1).[10] This high mobility allows the fabrication of higher-speed P-channel field effect transistors, which are required for CMOS logic. Because they lack a fast CMOS structure, GaAs circuits must use logic styles which have much higher power consumption; this has made GaAs circuits less able to compete with silicon logic circuits.

For manufacturing solar cells, silicon has relatively low absorptivity for the sunlight meaning about 100 micrometers of Si is needed to absorb most sunlight. Such a layer is relatively robust and easy to handle. In contrast, the absorptivity of GaAs is so high that only a few micrometers of thickness are needed to absorb all of the light. Consequently GaAs thin films must be supported on a substrate material.[11]

Silicon is a pure element, avoiding the problems of stoichiometric imbalance and thermal unmixing of GaAs.[citation needed]

Silicon has a nearly perfect lattice, impurity density is very low and allows very small structures to be built (currently down to 16 nm[12]). GaAs in contrast has a very high impurity density,[citation needed] which makes it difficult to build integrated circuits with small structures, so the 500 nm process is a common process for GaAs.
High-efficiency, triple-junction gallium arsenide solar cells covering the MidSTAR-1 satellite

Other applications

Solar cells and detectors

Another important application of GaAs is for high efficiency solar cells. Gallium arsenide (GaAs) is also known as single-crystalline thin film and are high-cost high-efficiency solar cells.

In 1970, the first GaAs heterostructure solar cells were created by the team led by Zhores Alferov in the USSR.[13][14][15] In the early 1980s, the efficiency of the best GaAs solar cells surpassed that of silicon solar cells, and in the 1990s GaAs solar cells took over from silicon as the cell type most commonly used for Photovoltaic arrays for satellite applications. Later, dual- and triple-junction solar cells based on GaAs with germanium and indium gallium phosphide layers were developed as the basis of a triple-junction solar cell, which held a record efficiency of over 32% and can operate also with light as concentrated as 2,000 suns. This kind of solar cell powers the rovers Spirit and Opportunity, which are exploring Mars' surface. Also many solar cars utilize GaAs in solar arrays.
GaAs-based devices hold the world record for the highest-efficiency single-junction solar cell at 28.8%.[16] This high efficiency is attributed to the extreme high quality GaAs epitaxial growth, surface passivation by the AlGaAs,[17] and the promotion of photon recycling by the thin film design.[18]

Complex designs of AlxGa1−xAs-GaAs devices can be sensitive to infrared radiation (QWIP).
GaAs diodes can be used for the detection of X-rays.[19]

Light-emission devices

Band structure of GaAs. The direct gap of GaAs results in efficient emission of infrared light at 1.424 eV (~870 nm).

GaAs has been used to produce (near-infrared) laser diodes since 1962.[20]

Safety

The environment, health and safety aspects of gallium arsenide sources (such as trimethylgallium and arsine) and industrial hygiene monitoring studies of metalorganic precursors have been reported.[21] California lists gallium arsenide as a carcinogen.[22] However, there is no evidence for a primary carcinogenic effect of GaAs.[23]

Study of aerosols stands to improve climate models

Study of aerosols stands to improve climate models

2 hours ago by Kimm Fesenmaier, from http://phys.org/news/2014-08-aerosols-climate.html 
Study of aerosols stands to improve climate models





















Clouds over the southern Indian Ocean. This image was acquired by one of the northward-viewing cameras of the Multi-angle Imaging SpectroRadiometer (MISR) instrument on NASA's polar-orbiting Terra spacecraft. Credit: NASA/JPL-Caltech
(Phys.org) —Aerosols, tiny particles in the atmosphere, play a significant role in Earth's climate, scattering and absorbing incoming sunlight and affecting the formation and properties of clouds. Currently, the effect that these aerosols have on clouds represents the largest uncertainty among all influences on climate change.

But now researchers from Caltech and the Jet Propulsion Laboratory have provided a global observational study of the effect that changes in aerosol levels have on low-level marine clouds—the clouds that have the largest impact on the amount of that Earth reflects back into space. The findings appear in the advance online version of the journal Nature Geoscience.

Changes in aerosol levels have two main effects—they alter the amount of clouds in the atmosphere and they change the internal properties of those clouds. Using measurements from several of NASA's Earth-monitoring satellites from August 2006 through April 2011, the researchers quantified for the first time these two effects from 7.3 million individual data points.

"If you combine these two effects, you get an aerosol influence almost twice that estimated in the latest report from the Intergovernmental Panel on Climate Change," says John Seinfeld, the Louis E. Nohl Professor and professor of chemical engineering at Caltech. "These results offer unique guidance on how warm cloud processes should be incorporated in with changing aerosol levels."
Explore further: Tagging tiny particles in turbulent clouds

More information: "Satellite-based estimate of global aerosol–cloud radiative forcing by marine warm clouds." Yi-Chun Chen, Matthew W. Christensen, Graeme L. Stephens & John H. Seinfeld. Nature Geoscience (2014) DOI: 10.1038/ngeo2214. Received 15 April 2014 Accepted 03 July 2014 Published online 03 August 2014
Journal reference: Nature Geoscience

 Read more at: http://phys.org/news/2014-08-aerosols-climate.html#jCp

Carl Sagan

Carl Sagan

From Wikipedia, the free encyclopedia
Carl Sagan
Carl Sagan Planetary Society.JPG
Carl Sagan in 1980
BornCarl Edward Sagan
(1934-11-09)November 9, 1934
Brooklyn, New York, U.S.
DiedDecember 20, 1996(1996-12-20) (aged 62)
Seattle, Washington, U.S.
ResidenceUnited States[1]
NationalityUnited States of America
FieldsAstronomy, astrophysics, cosmology, astrobiology, space science, planetary science
InstitutionsCornell University
Harvard University
Smithsonian Astrophysical Observatory
University of California, Berkeley
Alma materUniversity of Chicago
(B.A.), (BSc), (MSc), (PhD)
Doctoral advisorGerard Kuiper
Known forSearch for Extra-Terrestrial Intelligence (SETI)
Cosmos: A Personal Voyage
Cosmos
Voyager Golden Record
Pioneer plaque
Contact
Pale Blue Dot
Notable awardsNASA Distinguished Public Service Medal (1977)
Pulitzer Prize for General Non-Fiction (1978)
Oersted Medal (1990)
Carl Sagan Award for Public Understanding of Science (1993)
National Academy of Sciences Public Welfare Medal (1994)
SpouseLynn Margulis
(1957–65; divorced; 2 children)
Linda Salzman
(1968–81; divorced; 1 child)
Ann Druyan
(1981–96; his death; 2 children)
Signature

Carl Edward Sagan (/ˈsɡən/; November 9, 1934 – December 20, 1996) was an American astronomer, astrophysicist, cosmologist, author, science popularizer and science communicator in astronomy and other natural sciences. His contributions were central to the discovery of the high surface temperatures of Venus. However, he is best known for his contributions to the scientific research of extraterrestrial life, including experimental demonstration of the production of amino acids from basic chemicals by radiation. Sagan assembled the first physical messages that were sent into space: the Pioneer plaque and the Voyager Golden Record, universal messages that could potentially be understood by any extraterrestrial intelligence that might find them.

He published more than 600 scientific papers[2] and articles and was author, co-author or editor of more than 20 books. Sagan is known for many of his popular science books, such as The Dragons of Eden, Broca's Brain and Pale Blue Dot, and for the award-winning 1980 television series Cosmos: A Personal Voyage, which he narrated and co-wrote. The most widely watched series in the history of American public television, Cosmos has been seen by at least 500 million people across 60 different countries.[3] The book Cosmos was published to accompany the series. He also wrote the science fiction novel Contact, the basis for a 1997 film of the same name.

Sagan always advocated scientific skeptical inquiry and the scientific method, pioneered exobiology and promoted the Search for Extra-Terrestrial Intelligence (SETI). He spent most of his career as a professor of astronomy at Cornell University, where he directed the Laboratory for Planetary Studies. Sagan and his works received numerous awards and honors, including the NASA Distinguished Public Service Medal, the National Academy of Sciences Public Welfare Medal, the Pulitzer Prize for General Non-Fiction for his book The Dragons of Eden, and, regarding Cosmos: A Personal Voyage, two Emmy Awards, the Peabody Award and the Hugo Award. He married three times and had five children. After suffering from myelodysplasia, Sagan died of pneumonia at the age of 62 on December 20, 1996.

Inquisitiveness about nature

Soon after entering elementary school he began to express a strong inquisitiveness about nature. Sagan recalled taking his first trips to the public library alone, at the age of five, when his mother got him a library card. He wanted to learn what stars were, since none of his friends or their parents could give him a clear answer:
I went to the librarian and asked for a book about stars ... And the answer was stunning. It was that the Sun was a star but really close. The stars were suns, but so far away they were just little points of light ... The scale of the universe suddenly opened up to me. It was a kind of religious experience. There was a magnificence to it, a grandeur, a scale which has never left me. Never ever left me.[7]:18
At about age six or seven, he and a close friend took trips to the American Museum of Natural History in New York City. While there, they went to the Hayden Planetarium and walked around the museum's exhibits of space objects, such as meteorites, and displays of dinosaurs and animals in natural settings. Sagan writes about those visits:
I was transfixed by the dioramas—lifelike representations of animals and their habitats all over the world. Penguins on the dimly lit Antarctic ice; ... a family of gorillas, the male beating his chest, ... an American grizzly bear standing on his hind legs, ten or twelve feet tall, and staring me right in the eye.[7]:18
His parents helped nurture his growing interest in science by buying him chemistry sets and reading materials.[9] His interest in space, however, was his primary focus, especially after reading science fiction stories by writers such as Edgar Rice Burroughs, which stirred his imagination about life on other planets such as Mars. According to biographer Ray Spangenburg, these early years as Sagan tried to understand the mysteries of the planets became a "driving force in his life, a continual spark to his intellect, and a quest that would never be forgotten."[8]

Education and scientific career

He attended the University of Chicago, where he participated in the Ryerson Astronomical Society,[10] received a bachelor of arts in self-proclaimed "nothing" with general and special honors in 1954, a bachelor of science in physics in 1955, and a master of science in physics in 1956 before earning a PhD in astronomy and astrophysics in 1960.[11][12][13] During his time as an honors program undergraduate, Sagan worked in the laboratory of the geneticist H. J. Muller and wrote a thesis on the origins of life with physical chemist H. C. Urey. He used the summer months of his graduate studies to work with planetary scientist Gerard Kuiper (thesis advisor), physicist George Gamow, and chemist Melvin Calvin. From 1960 to 1962 Sagan was a Miller Fellow at the University of California, Berkeley.[14] From 1962 to 1968, he worked at the Smithsonian Astrophysical Observatory in Cambridge, Massachusetts. At the same time, he worked with geneticist Joshua Lederberg.

Sagan lectured and did research at Harvard University until 1968, when he moved to Cornell University in Ithaca, New York, after being denied tenure at Harvard. It has been suggested that Sagan was denied tenure in part because of his publicized scientific advocacy, which some scientists perceived as being self-promotion.[15] He became a full professor at Cornell in 1971, and directed the Laboratory for Planetary Studies there. From 1972 to 1981, Sagan was associate director of the Center for Radiophysics and Space Research (CRSR) at Cornell.

Sagan was associated with the U.S. space program from its inception. From the 1950s onward, he worked as an advisor to NASA, where one of his duties included briefing the Apollo astronauts before their flights to the Moon. Sagan contributed to many of the robotic spacecraft missions that explored the Solar System, arranging experiments on many of the expeditions. He conceived the idea of adding an unalterable and universal message on spacecraft destined to leave the Solar System that could potentially be understood by any extraterrestrial intelligence that might find it. Sagan assembled the first physical message that was sent into space: a gold-anodized plaque, attached to the space probe Pioneer 10, launched in 1972. Pioneer 11, also carrying another copy of the plaque, was launched the following year. He continued to refine his designs; the most elaborate message he helped to develop and assemble was the Voyager Golden Record that was sent out with the Voyager space probes in 1977. Sagan often challenged the decisions to fund the Space Shuttle and the International Space Station at the expense of further robotic missions.[16]

Sagan taught a course on critical thinking at Cornell University until he died in 1996 from pneumonia, a few months after finding that he was in remission of myelodysplastic syndrome.

Scientific achievements

Former student David Morrison describes Sagan as "an 'idea person' and a master of intuitive physical arguments and 'back of the envelope' calculations,"[15] and Gerard Kuiper said that "Some persons work best in specializing on a major program in the laboratory; others are best in liaison between sciences. Dr. Sagan belongs in the latter group."[15]

Sagan's contributions were central to the discovery of the high surface temperatures of the planet Venus. In the early 1960s no one knew for certain the basic conditions of that planet's surface, and Sagan listed the possibilities in a report later depicted for popularization in a Time–Life book, Planets. His own view was that Venus was dry and very hot as opposed to the balmy paradise others had imagined. He had investigated radio emissions from Venus and concluded that there was a surface temperature of 500 °C (900 °F). As a visiting scientist to NASA's Jet Propulsion Laboratory, he contributed to the first Mariner missions to Venus, working on the design and management of the project. Mariner 2 confirmed his conclusions on the surface conditions of Venus in 1962.

Sagan was among the first to hypothesize that Saturn's moon Titan might possess oceans of liquid compounds on its surface and that Jupiter's moon Europa might possess subsurface oceans of water.
This would make Europa potentially habitable.[17] Europa's subsurface ocean of water was later indirectly confirmed by the spacecraft Galileo. The mystery of Titan's reddish haze was also solved with Sagan's help. The reddish haze was revealed to be due to complex organic molecules constantly raining down onto Titan's surface.[18]

He further contributed insights regarding the atmospheres of Venus and Jupiter as well as seasonal changes on Mars. He also perceived global warming as a growing, man-made danger and likened it to the natural development of Venus into a hot, life-hostile planet through a kind of runaway greenhouse effect.[19] Sagan and his Cornell colleague Edwin Ernest Salpeter speculated about life in Jupiter's clouds, given the planet's dense atmospheric composition rich in organic molecules. He studied the observed color variations on Mars' surface and concluded that they were not seasonal or vegetational changes as most believed but shifts in surface dust caused by windstorms.

Sagan is best known, however, for his research on the possibilities of extraterrestrial life, including experimental demonstration of the production of amino acids from basic chemicals by radiation.[20]
He is also the 1994 recipient of the Public Welfare Medal, the highest award of the National Academy of Sciences for "distinguished contributions in the application of science to the public welfare".[21] He was denied membership in the Academy, reportedly because his media activities made him unpopular with many other scientists.[22][23][24]

Scientific and critical thinking advocacy

Sagan's ability to convey his ideas allowed many people to understand the cosmos better—simultaneously emphasizing the value and worthiness of the human race, and the relative insignificance of the Earth in comparison to the Universe. He delivered the 1977 series of Royal Institution Christmas Lectures in London.[25] He hosted and, with Ann Druyan, co-wrote and co-produced the highly popular thirteen-part Public Broadcasting Service (PBS) television series Cosmos: A Personal Voyage.[26]
Sagan in Cosmos (1980)

Cosmos covered a wide range of scientific subjects including the origin of life and a perspective of our place in the Universe. The series was first broadcast by PBS in 1980, winning an Emmy[27] and a Peabody Award. It has been broadcast in more than 60 countries and seen by over 500 million people,[3][28] making it the most widely watched PBS program in history.[29] In addition, Time magazine ran a cover story about Sagan soon after the show broadcast, referring to him as "creator, chief writer and host-narrator of the new public television series Cosmos, [and] takes the controls of his fantasy spaceship".[30] However, Sagan was criticized for putting too much attention into the series, with several of his classes at Cornell being cancelled and complaints from his colleagues.[15]

Sagan was a proponent of the search for extraterrestrial life. He urged the scientific community to listen with radio telescopes for signals from potential intelligent extraterrestrial life-forms. Sagan was so persuasive that by 1982 he was able to get a petition advocating SETI published in the journal Science and signed by 70 scientists, including seven Nobel Prize winners. This was a tremendous increase in the respectability of this controversial field. Sagan also helped Frank Drake write the Arecibo message, a radio message beamed into space from the Arecibo radio telescope on November 16, 1974, aimed at informing potential extraterrestrials about Earth.

Sagan was chief technology officer of the professional planetary research journal Icarus for twelve years. He co-founded The Planetary Society, the largest space-interest group in the world, with over 100,000 members in more than 149 countries, and was a member of the SETI Institute Board of Trustees. Sagan served as Chairman of the Division for Planetary Science of the American Astronomical Society, as President of the Planetology Section of the American Geophysical Union, and as Chairman of the Astronomy Section of the American Association for the Advancement of Science (AAAS).
The Planetary Society members at the organization's founding. Carl Sagan is seated on the right.

At the height of the Cold War, Sagan became involved in public awareness efforts for the effects of nuclear war when a mathematical climate model suggested that a substantial nuclear exchange could upset the delicate balance of life on Earth. He was one of five authors—the "S"—of the "TTAPS" report, as the research paper came to be known. He eventually co-authored the scientific paper hypothesizing a global nuclear winter following nuclear war.[31] He also co-authored the book A Path Where No Man Thought: Nuclear Winter and the End of the Arms Race, a comprehensive examination of the phenomenon of nuclear winter.

Sagan also wrote books to popularize science, such as Cosmos, which reflected and expanded upon some of the themes of A Personal Voyage and became the best-selling science book ever published in English;[32] The Dragons of Eden: Speculations on the Evolution of Human Intelligence, which won a Pulitzer Prize; and Broca's Brain: Reflections on the Romance of Science. Sagan also wrote the best-selling science fiction novel Contact in 1985, based on a film treatment he wrote with his wife in 1979, but he did not live to see the book's 1997 motion picture adaptation, which starred Jodie Foster and won the 1998 Hugo Award for Best Dramatic Presentation.

He wrote a sequel to Cosmos, Pale Blue Dot: A Vision of the Human Future in Space, which was selected as a notable book of 1995 by The New York Times. He appeared on PBS' Charlie Rose program in January 1995.[16] Sagan also wrote the introduction for Stephen Hawking's bestseller, A Brief History of Time. Sagan was also known for his popularization of science, his efforts to increase scientific understanding among the general public, and his positions in favor of scientific skepticism and against pseudoscience, such as his debunking of the Betty and Barney Hill abduction. To mark the tenth anniversary of Sagan's death, David Morrison, a former student of Sagan's, recalled "Sagan's immense contributions to planetary research, the public understanding of science, and the skeptical movement" in Skeptical Inquirer.[15]
Pale Blue Dot: Earth is a bright pixel when photographed from Voyager 1 six billion kilometers out (beyond Pluto). Sagan encouraged NASA to generate this image.

Sagan hypothesized in January 1991 that enough smoke from the 1991 Kuwaiti oil fires "might get so high as to disrupt agriculture in much of South Asia ..." He later conceded in The Demon-Haunted World that this prediction did not turn out to be correct: "it was pitch black at noon and temperatures dropped 4°–6 °C over the Persian Gulf, but not much smoke reached stratospheric altitudes and Asia was spared".[33] A 2007 study noted that modern computer models have been applied to the Kuwait oil fires, finding that individual smoke plumes are not able to loft smoke into the stratosphere, but that smoke from fires covering a large area, like some forest fires or the burning of cities that would be expected to follow a nuclear strike, would loft significant amounts of smoke into the stratosphere.[34][35][36][37]

In his later years Sagan advocated the creation of an organized search for near-Earth objects that might impact the Earth.[38] When others suggested creating large nuclear bombs that could be used to alter the orbit of a NEO that was predicted to hit the Earth, Sagan proposed the Deflection Dilemma: If we create the ability to deflect an asteroid away from the Earth, then we also create the ability to deflect an asteroid towards the Earth—providing an evil power with a true doomsday bomb.[39][40] His interest in the use of nuclear weapons in space grew out of his work in 1958 for the Armour Research Foundation's Project A119, concerning the possibility of detonating a nuclear device on the Lunar surface.[41]

Sagan was a critic of Plato. Sagan said of Plato: "Science and mathematics were to be removed from the hands of the merchants and the artisans. This tendency found its most effective advocate in a follower of Pythagoras named Plato." and "He (Plato) believed that ideas were far more real than the natural world. He advised the astronomers not to waste their time observing the stars and planets. It was better, he believed, just to think about them. Plato expressed hostility to observation and experiment. He taught contempt for the real world and disdain for the practical application of scientific knowledge. Plato's followers succeeded in extinguishing the light of science and experiment that had been kindled by Democritus and the other Ionians."[42]

Popularizing science

Speaking about his activities in popularizing science, Sagan said that there were at least two reasons for scientists to explain what science is about. Naked self-interest was one because much of the funding for science came from the public, and the public had a right to know how their money was being spent. If scientists increased public excitement about science, there was a good chance of having more public supporters. The other reason was the excitement of communicating one's own excitement about science to others.[43]

Phrase 'billions and billions'

 
Sagan with a model of the Viking lander which would land on Mars. Sagan examined possible landing sites for Viking along with Mike Carr and Hal Masursky.

From Cosmos and his frequent appearances on The Tonight Show Starring Johnny Carson, Sagan became associated with the catchphrase "billions and billions". Sagan said that he never actually used the phrase in the Cosmos series.[44] The closest that he ever came was in the book Cosmos, where he talked of "billions upon billions":[45]
A galaxy is composed of gas and dust and stars—billions upon billions of stars.
—Carl Sagan, Cosmos, page 3[19]
Precursor to Sagan, Richard Feynman is observed to use the phrase "billions and billions" multiple times in his "red books."

However, his frequent use of the word billions, and distinctive delivery emphasizing the "b" (which he did intentionally, in place of more cumbersome alternatives such as "billions with a 'b'", in order to distinguish the word from "millions" in viewers' minds),[44] made him a favorite target of comic performers, including Johnny Carson,[46] Gary Kroeger, Mike Myers, Bronson Pinchot, Penn Jillette, Harry Shearer, and others. Frank Zappa satirized the line in the song "Be in My Video", noting as well "atomic light". Sagan took this all in good humor, and his final book was entitled Billions and Billions, which opened with a tongue-in-cheek discussion of this catchphrase, observing that Carson was an amateur astronomer and that Carson's comic caricature often included real science.[44]

He is also known for expressing wonderment at the vastness of space and time, as in his phrase "The total number of stars in the Universe is larger than all the grains of sand on all the beaches of the planet Earth."

As a humorous tribute to Sagan and his association with the catchphrase "billions and billions", a sagan has been defined as a unit of measurement equivalent to a large number of anything.[47][48][49]

Social concerns

Sagan believed that the Drake equation, on substitution of reasonable estimates, suggested that a large number of extraterrestrial civilizations would form, but that the lack of evidence of such civilizations highlighted by the Fermi paradox suggests technological civilizations tend to self-destruct. This stimulated his interest in identifying and publicizing ways that humanity could destroy itself, with the hope of avoiding such a cataclysm and eventually becoming a spacefaring species.
Sagan's deep concern regarding the potential destruction of human civilization in a nuclear holocaust was conveyed in a memorable cinematic sequence in the final episode of Cosmos, called "Who Speaks for Earth?" Sagan had already resigned from the Air Force Scientific Advisory Board and voluntarily surrendered his top secret clearance in protest over the Vietnam War.[50] Following his marriage to his third wife (novelist Ann Druyan) in June 1981, Sagan became more politically active—particularly in opposing escalation of the nuclear arms race under President Ronald Reagan.
In March 1983, Reagan announced the Strategic Defense Initiative—a multi-billion dollar project to develop a comprehensive defense against attack by nuclear missiles, which was quickly dubbed the "Star Wars" program. Sagan spoke out against the project, arguing that it was technically impossible to develop a system with the level of perfection required, and far more expensive to build such a system than it would be for an enemy to defeat it through decoys and other means—and that its construction would seriously destabilize the nuclear balance between the United States and the Soviet Union, making further progress toward nuclear disarmament impossible.

When Soviet leader Mikhail Gorbachev declared a unilateral moratorium on the testing of nuclear weapons, which would begin on August 6, 1985—the 40th anniversary of the atomic bombing of Hiroshima—the Reagan administration dismissed the dramatic move as nothing more than propaganda, and refused to follow suit. In response, US anti-nuclear and peace activists staged a series of protest actions at the Nevada Test Site, beginning on Easter Sunday in 1986 and continuing through 1987. Hundreds of people were arrested, including Sagan, who was arrested on two separate occasions as he climbed over a chain-link fence at the test site.[51]

Personal life and beliefs

Sagan was married three times. In 1957, he married biologist Lynn Margulis, mother of Dorion Sagan and Jeremy Sagan. After Sagan and Margulis divorced, he married artist Linda Salzman in 1968, mother of Nick Sagan. During these marriages, Sagan focused heavily on his career, a factor which may have contributed to Sagan's first divorce.[15] In 1981, Sagan married author Ann Druyan, mother of Alexandra Rachel (Sasha) Sagan and Samuel Democritus Sagan. Sagan and Druyan remained married until his death in 1996.

Isaac Asimov described Sagan as one of only two people he ever met whose intellect surpassed his own. The other, he claimed, was the computer scientist and artificial intelligence expert Marvin Minsky.[52]

Sagan wrote frequently about religion and the relationship between religion and science, expressing his skepticism about the conventional conceptualization of God as a sapient being. For example:
Some people think God is an outsized, light-skinned male with a long white beard, sitting on a throne somewhere up there in the sky, busily tallying the fall of every sparrow. Others—for example Baruch Spinoza and Albert Einstein—considered God to be essentially the sum total of the physical laws which describe the universe. I do not know of any compelling evidence for anthropomorphic patriarchs controlling human destiny from some hidden celestial vantage point, but it would be madness to deny the existence of physical laws.[53]
In another description of his view on the concept of God, Sagan emphatically writes:
The idea that God is an oversized white male with a flowing beard who sits in the sky and tallies the fall of every sparrow is ludicrous. But if by God one means the set of physical laws that govern the universe, then clearly there is such a God. This God is emotionally unsatisfying ... it does not make much sense to pray to the law of gravity.[54]
On atheism, Sagan commented in 1981:
An atheist is someone who is certain that God does not exist, someone who has compelling evidence against the existence of God. I know of no such compelling evidence. Because God can be relegated to remote times and places and to ultimate causes, we would have to know a great deal more about the universe than we do now to be sure that no such God exists. To be certain of the existence of God and to be certain of the nonexistence of God seem to me to be the confident extremes in a subject so riddled with doubt and uncertainty as to inspire very little confidence indeed.[55]
Sagan also commented on Christianity, stating "My long-time view about Christianity is that it represents an amalgam of two seemingly immiscible parts, the religion of Jesus and the religion of Paul. Thomas Jefferson attempted to excise the Pauline parts of the New Testament. There wasn't much left when he was done, but it was an inspiring document."[56]

Regarding the relationship between spirituality and science, Sagan stated: "Science is not only compatible with spirituality; it is a profound source of spirituality. When we recognize our place in an immensity of light-years and in the passage of ages, when we grasp the intricacy, beauty, and subtlety of life, then that soaring feeling, that sense of elation and humility combined, is surely spiritual."[57]

An environmental appeal, "Preserving and Cherishing the Earth", signed by Sagan with other noted scientists in January 1990, stated that "The historical record makes clear that religious teaching, example, and leadership are powerfully able to influence personal conduct and commitment... Thus, there is a vital role for religion and science."[58]

In reply to a question in 1996 about his religious beliefs, Sagan answered, "I'm agnostic."[59] Sagan's views on religion have been interpreted as a form of pantheism comparable to Einstein's belief in Spinoza's God.[60] Sagan maintained that the idea of a creator of the Universe was difficult to prove or disprove and that the only conceivable scientific discovery that could challenge it would be an infinitely old Universe.[61] His last wife, Ann Druyan, stated:
When my husband died, because he was so famous and known for not being a believer, many people would come up to me—it still sometimes happens—and ask me if Carl changed at the end and converted to a belief in an afterlife. They also frequently ask me if I think I will see him again. Carl faced his death with unflagging courage and never sought refuge in illusions. The tragedy was that we knew we would never see each other again. I don't ever expect to be reunited with Carl.[62]
In 2006, Ann Druyan edited Sagan's 1985 Glasgow Gifford Lectures in Natural Theology into a book, The Varieties of Scientific Experience: A Personal View of the Search for God, in which he elaborates on his views of divinity in the natural world.
Carl Sagan (center) speaks with CDC employees in 1988.

Sagan is also widely regarded as a freethinker or skeptic; one of his most famous quotations, in Cosmos, was, "Extraordinary claims require extraordinary evidence"[63] (called the "Sagan Standard" by some[64]). This was based on a nearly identical statement by fellow founder of the Committee for the Scientific Investigation of Claims of the Paranormal, Marcello Truzzi, "An extraordinary claim requires extraordinary proof."[65][66] This idea had been earlier aphorized in Théodore Flournoy's work From India to the Planet Mars (1899) from a longer quote by Pierre-Simon Laplace (1749–1827), a French mathematician and astronomer, as the Principle of Laplace: "The weight of the evidence should be proportioned to the strangeness of the facts."[67]

Late in his life, Sagan's books elaborated on his skeptical, naturalistic view of the world. In The Demon-Haunted World, he presented tools for testing arguments and detecting fallacious or fraudulent ones, essentially advocating wide use of critical thinking and the scientific method. The compilation Billions and Billions: Thoughts on Life and Death at the Brink of the Millennium, published in 1997 after Sagan's death, contains essays written by Sagan, such as his views on abortion, and his widow Ann Druyan's account of his death as a skeptic, agnostic, and freethinker.

Sagan warned against humans' tendency towards anthropocentrism. He was the faculty adviser for the Cornell Students for the Ethical Treatment of Animals. In the Cosmos chapter "Blues For a Red Planet", Sagan wrote, "If there is life on Mars, I believe we should do nothing with Mars. Mars then belongs to the Martians, even if the Martians are only microbes."[68]

Sagan was a user and advocate of marijuana. Under the pseudonym "Mr. X", he contributed an essay about smoking cannabis to the 1971 book Marihuana Reconsidered.[69][70] The essay explained that marijuana use had helped to inspire some of Sagan's works and enhance sensual and intellectual experiences. After Sagan's death, his friend Lester Grinspoon disclosed this information to Sagan's biographer, Keay Davidson. The publishing of the biography, Carl Sagan: A Life, in 1999 brought media attention to this aspect of Sagan's life.[71][72][73] Not long after his death, widow Ann Druyan had gone on to preside over the board of directors of the National Organization for the Reform of Marijuana Laws (NORML), a non-profit organization dedicated to reforming cannabis laws.[74][75]

In 1994, engineers at Apple Computer code-named the Power Macintosh 7100 "Carl Sagan" in the hope that Apple would make "billions and billions" with the sale of the PowerMac 7100.[4] The name was only used internally, but Sagan was concerned that it would become a product endorsement and sent Apple a cease-and-desist letter. Apple complied, but engineers retaliated by changing the internal codename to "BHA" for “Butt-Head Astronomer”.[76][77] Sagan then sued Apple for libel, a form of defamation, in federal court. The court granted Apple's motion to dismiss Sagan's claims and opined in dicta that a reader aware of the context would understand Apple was "clearly attempting to retaliate in a humorous and satirical way", and that “It strains reason to conclude that Defendant was attempting to criticize Plaintiff's reputation or competency as an astronomer. One does not seriously attack the expertise of a scientist using the undefined phrase ‘butt-head’.”[76][78] Sagan then sued for Apple's original use of his name and likeness, but again lost.[79] Sagan appealed the ruling.[79] In November 1995, an out-of-court settlement was reached and Apple's office of trademarks and patents released a conciliatory statement that “Apple has always had great respect for Dr. Sagan. It was never Apple's intention to cause Dr. Sagan or his family any embarrassment or concern.”[80] Apple's third and final code name for the project was "LAW", short for "Lawyers are Wimps".[77]

Sagan briefly served as an adviser on Stanley Kubrick's film 2001: A Space Odyssey.[7]:168 Sagan proposed that the film suggest, rather than depict, extraterrestrial superintelligence.[81]

Gene

From Wikipedia, the free encyclopedia https://en.wikipedia.org/wiki/Gene Chromosome ...