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Tuesday, May 23, 2023

Gamma ray

From Wikipedia, the free encyclopedia
https://en.wikipedia.org/wiki/Gamma_ray
 
Illustration of an emission of a gamma ray (γ) from an atomic nucleus
 
Gamma rays are emitted during nuclear fission in nuclear explosions.
 
NASA guide to electromagnetic spectrum showing overlap of frequency between X-rays and gamma rays

A gamma ray, also known as gamma radiation (symbol γ or ), is a penetrating form of electromagnetic radiation arising from the radioactive decay of atomic nuclei. It consists of the shortest wavelength electromagnetic waves, typically shorter than those of X-rays. With frequencies above 30 exahertz (3×1019 Hz), it imparts the highest photon energy. Paul Villard, a French chemist and physicist, discovered gamma radiation in 1900 while studying radiation emitted by radium. In 1903, Ernest Rutherford named this radiation gamma rays based on their relatively strong penetration of matter; in 1900 he had already named two less penetrating types of decay radiation (discovered by Henri Becquerel) alpha rays and beta rays in ascending order of penetrating power.

Gamma rays from radioactive decay are in the energy range from a few kiloelectronvolts (keV) to approximately 8 megaelectronvolts (MeV), corresponding to the typical energy levels in nuclei with reasonably long lifetimes. The energy spectrum of gamma rays can be used to identify the decaying radionuclides using gamma spectroscopy. Very-high-energy gamma rays in the 100–1000 teraelectronvolt (TeV) range have been observed from sources such as the Cygnus X-3 microquasar.

Natural sources of gamma rays originating on Earth are mostly a result of radioactive decay and secondary radiation from atmospheric interactions with cosmic ray particles. However, there are other rare natural sources, such as terrestrial gamma-ray flashes, which produce gamma rays from electron action upon the nucleus. Notable artificial sources of gamma rays include fission, such as that which occurs in nuclear reactors, and high energy physics experiments, such as neutral pion decay and nuclear fusion.

Gamma rays and X-rays are both electromagnetic radiation, and since they overlap in the electromagnetic spectrum, the terminology varies between scientific disciplines. In some fields of physics, they are distinguished by their origin: Gamma rays are created by nuclear decay while X-rays originate outside the nucleus. In astrophysics, gamma rays are conventionally defined as having photon energies above 100 keV and are the subject of gamma ray astronomy, while radiation below 100 keV is classified as X-rays and is the subject of X-ray astronomy.

Gamma rays are ionizing radiation and are thus hazardous to life. Due to their high penetration power, they can damage bone marrow and internal organs. Unlike alpha and beta rays, they easily pass through the body and thus pose a formidable radiation protection challenge, requiring shielding made from dense materials such as lead or concrete. On Earth, the magnetosphere protects life from most types of lethal cosmic radiation other than gamma rays.

History of discovery

The first gamma ray source to be discovered was the radioactive decay process called gamma decay. In this type of decay, an excited nucleus emits a gamma ray almost immediately upon formation. Paul Villard, a French chemist and physicist, discovered gamma radiation in 1900, while studying radiation emitted from radium. Villard knew that his described radiation was more powerful than previously described types of rays from radium, which included beta rays, first noted as "radioactivity" by Henri Becquerel in 1896, and alpha rays, discovered as a less penetrating form of radiation by Rutherford, in 1899. However, Villard did not consider naming them as a different fundamental type. Later, in 1903, Villard's radiation was recognized as being of a type fundamentally different from previously named rays by Ernest Rutherford, who named Villard's rays "gamma rays" by analogy with the beta and alpha rays that Rutherford had differentiated in 1899. The "rays" emitted by radioactive elements were named in order of their power to penetrate various materials, using the first three letters of the Greek alphabet: alpha rays as the least penetrating, followed by beta rays, followed by gamma rays as the most penetrating. Rutherford also noted that gamma rays were not deflected (or at least, not easily deflected) by a magnetic field, another property making them unlike alpha and beta rays.

Gamma rays were first thought to be particles with mass, like alpha and beta rays. Rutherford initially believed that they might be extremely fast beta particles, but their failure to be deflected by a magnetic field indicated that they had no charge. In 1914, gamma rays were observed to be reflected from crystal surfaces, proving that they were electromagnetic radiation. Rutherford and his co-worker Edward Andrade measured the wavelengths of gamma rays from radium, and found they were similar to X-rays, but with shorter wavelengths and thus, higher frequency. This was eventually recognized as giving them more energy per photon, as soon as the latter term became generally accepted. A gamma decay was then understood to usually emit a gamma photon.

Sources

Natural sources of gamma rays on Earth include gamma decay from naturally occurring radioisotopes such as potassium-40, and also as a secondary radiation from various atmospheric interactions with cosmic ray particles. Some rare terrestrial natural sources that produce gamma rays that are not of a nuclear origin, are lightning strikes and terrestrial gamma-ray flashes, which produce high energy emissions from natural high-energy voltages. Gamma rays are produced by a number of astronomical processes in which very high-energy electrons are produced. Such electrons produce secondary gamma rays by the mechanisms of bremsstrahlung, inverse Compton scattering and synchrotron radiation. A large fraction of such astronomical gamma rays are screened by Earth's atmosphere. Notable artificial sources of gamma rays include fission, such as occurs in nuclear reactors, as well as high energy physics experiments, such as neutral pion decay and nuclear fusion.

A sample of gamma ray-emitting material that is used for irradiating or imaging is known as a gamma source. It is also called a radioactive source, isotope source, or radiation source, though these more general terms also apply to alpha and beta-emitting devices. Gamma sources are usually sealed to prevent radioactive contamination, and transported in heavy shielding.

Radioactive decay (gamma decay)

Gamma rays are produced during gamma decay, which normally occurs after other forms of decay occur, such as alpha or beta decay. A radioactive nucleus can decay by the emission of an
α
or
β
particle. The daughter nucleus that results is usually left in an excited state. It can then decay to a lower energy state by emitting a gamma ray photon, in a process called gamma decay.

The emission of a gamma ray from an excited nucleus typically requires only 10−12 seconds. Gamma decay may also follow nuclear reactions such as neutron capture, nuclear fission, or nuclear fusion. Gamma decay is also a mode of relaxation of many excited states of atomic nuclei following other types of radioactive decay, such as beta decay, so long as these states possess the necessary component of nuclear spin. When high-energy gamma rays, electrons, or protons bombard materials, the excited atoms emit characteristic "secondary" gamma rays, which are products of the creation of excited nuclear states in the bombarded atoms. Such transitions, a form of nuclear gamma fluorescence, form a topic in nuclear physics called gamma spectroscopy. Formation of fluorescent gamma rays are a rapid subtype of radioactive gamma decay.

In certain cases, the excited nuclear state that follows the emission of a beta particle or other type of excitation, may be more stable than average, and is termed a metastable excited state, if its decay takes (at least) 100 to 1000 times longer than the average 10−12 seconds. Such relatively long-lived excited nuclei are termed nuclear isomers, and their decays are termed isomeric transitions. Such nuclei have half-lifes that are more easily measurable, and rare nuclear isomers are able to stay in their excited state for minutes, hours, days, or occasionally far longer, before emitting a gamma ray. The process of isomeric transition is therefore similar to any gamma emission, but differs in that it involves the intermediate metastable excited state(s) of the nuclei. Metastable states are often characterized by high nuclear spin, requiring a change in spin of several units or more with gamma decay, instead of a single unit transition that occurs in only 10−12 seconds. The rate of gamma decay is also slowed when the energy of excitation of the nucleus is small.

An emitted gamma ray from any type of excited state may transfer its energy directly to any electrons, but most probably to one of the K shell electrons of the atom, causing it to be ejected from that atom, in a process generally termed the photoelectric effect (external gamma rays and ultraviolet rays may also cause this effect). The photoelectric effect should not be confused with the internal conversion process, in which a gamma ray photon is not produced as an intermediate particle (rather, a "virtual gamma ray" may be thought to mediate the process).

Decay schemes

Radioactive decay scheme of 60
Co

Gamma emission spectrum of cobalt-60

One example of gamma ray production due to radionuclide decay is the decay scheme for cobalt-60, as illustrated in the accompanying diagram. First, 60
Co
decays to excited 60
Ni
by beta decay emission of an electron of 0.31 MeV. Then the excited 60
Ni
decays to the ground state (see nuclear shell model) by emitting gamma rays in succession of 1.17 MeV followed by 1.33 MeV. This path is followed 99.88% of the time:

60
27
Co
 
→  60
28
Ni*
 

e
 

ν
e
 

γ
 
1.17 MeV
60
28
Ni*
 
→  60
28
Ni
 
       
γ
 
1.33 MeV

Another example is the alpha decay of 241
Am
to form 237
Np
; which is followed by gamma emission. In some cases, the gamma emission spectrum of the daughter nucleus is quite simple, (e.g. 60
Co
/60
Ni
) while in other cases, such as with (241
Am
/237
Np
and 192
Ir
/192
Pt
), the gamma emission spectrum is complex, revealing that a series of nuclear energy levels exist.

Particle physics

Gamma rays are produced in many processes of particle physics. Typically, gamma rays are the products of neutral systems which decay through electromagnetic interactions (rather than a weak or strong interaction). For example, in an electron–positron annihilation, the usual products are two gamma ray photons. If the annihilating electron and positron are at rest, each of the resulting gamma rays has an energy of ~ 511 keV and frequency of ~ 1.24×1020 Hz. Similarly, a neutral pion most often decays into two photons. Many other hadrons and massive bosons also decay electromagnetically. High energy physics experiments, such as the Large Hadron Collider, accordingly employ substantial radiation shielding. Because subatomic particles mostly have far shorter wavelengths than atomic nuclei, particle physics gamma rays are generally several orders of magnitude more energetic than nuclear decay gamma rays. Since gamma rays are at the top of the electromagnetic spectrum in terms of energy, all extremely high-energy photons are gamma rays; for example, a photon having the Planck energy would be a gamma ray.

Other sources

A few gamma rays in astronomy are known to arise from gamma decay (see discussion of SN1987A), but most do not.

Photons from astrophysical sources that carry energy in the gamma radiation range are often explicitly called gamma-radiation. In addition to nuclear emissions, they are often produced by sub-atomic particle and particle-photon interactions. Those include electron-positron annihilation, neutral pion decay, bremsstrahlung, inverse Compton scattering, and synchrotron radiation.

Laboratory sources

In October 2017, scientists from various European universities proposed a means for sources of GeV photons using lasers as exciters through a controlled interplay between the cascade and anomalous radiative trapping.

Terrestrial thunderstorms

Thunderstorms can produce a brief pulse of gamma radiation called a terrestrial gamma-ray flash. These gamma rays are thought to be produced by high intensity static electric fields accelerating electrons, which then produce gamma rays by bremsstrahlung as they collide with and are slowed by atoms in the atmosphere. Gamma rays up to 100 MeV can be emitted by terrestrial thunderstorms, and were discovered by space-borne observatories. This raises the possibility of health risks to passengers and crew on aircraft flying in or near thunderclouds.

Solar flares

The most effusive solar flares emit across the entire EM spectrum, including γ-rays. The first confident observation occurred in 1972.

Cosmic rays

Extraterrestrial, high energy gamma rays include the gamma ray background produced when cosmic rays (either high speed electrons or protons) collide with ordinary matter, producing pair-production gamma rays at 511 keV. Alternatively, bremsstrahlung are produced at energies of tens of MeV or more when cosmic ray electrons interact with nuclei of sufficiently high atomic number (see gamma ray image of the Moon near the end of this article, for illustration).

Image of entire sky in 100 MeV or greater gamma rays as seen by the EGRET instrument aboard the CGRO spacecraft. Bright spots within the galactic plane are pulsars while those above and below the plane are thought to be quasars.

Pulsars and magnetars

The gamma ray sky (see illustration at right) is dominated by the more common and longer-term production of gamma rays that emanate from pulsars within the Milky Way. Sources from the rest of the sky are mostly quasars. Pulsars are thought to be neutron stars with magnetic fields that produce focused beams of radiation, and are far less energetic, more common, and much nearer sources (typically seen only in our own galaxy) than are quasars or the rarer gamma-ray burst sources of gamma rays. Pulsars have relatively long-lived magnetic fields that produce focused beams of relativistic speed charged particles, which emit gamma rays (bremsstrahlung) when those strike gas or dust in their nearby medium, and are decelerated. This is a similar mechanism to the production of high-energy photons in megavoltage radiation therapy machines (see bremsstrahlung). Inverse Compton scattering, in which charged particles (usually electrons) impart energy to low-energy photons boosting them to higher energy photons. Such impacts of photons on relativistic charged particle beams is another possible mechanism of gamma ray production. Neutron stars with a very high magnetic field (magnetars), thought to produce astronomical soft gamma repeaters, are another relatively long-lived star-powered source of gamma radiation.

Quasars and active galaxies

More powerful gamma rays from very distant quasars and closer active galaxies are thought to have a gamma ray production source similar to a particle accelerator. High energy electrons produced by the quasar, and subjected to inverse Compton scattering, synchrotron radiation, or bremsstrahlung, are the likely source of the gamma rays from those objects. It is thought that a supermassive black hole at the center of such galaxies provides the power source that intermittently destroys stars and focuses the resulting charged particles into beams that emerge from their rotational poles. When those beams interact with gas, dust, and lower energy photons they produce X-rays and gamma rays. These sources are known to fluctuate with durations of a few weeks, suggesting their relatively small size (less than a few light-weeks across). Such sources of gamma and X-rays are the most commonly visible high intensity sources outside the Milky Way galaxy. They shine not in bursts (see illustration), but relatively continuously when viewed with gamma ray telescopes. The power of a typical quasar is about 1040 watts, a small fraction of which is gamma radiation. Much of the rest is emitted as electromagnetic waves of all frequencies, including radio waves.

A hypernova. Artist's illustration showing the life of a massive star as nuclear fusion converts lighter elements into heavier ones. When fusion no longer generates enough pressure to counteract gravity, the star rapidly collapses to form a black hole. Theoretically, energy may be released during the collapse along the axis of rotation to form a long duration gamma-ray burst.

Gamma-ray bursts

The most intense sources of gamma rays, are also the most intense sources of any type of electromagnetic radiation presently known. They are the "long duration burst" sources of gamma rays in astronomy ("long" in this context, meaning a few tens of seconds), and they are rare compared with the sources discussed above. By contrast, "short" gamma-ray bursts of two seconds or less, which are not associated with supernovae, are thought to produce gamma rays during the collision of pairs of neutron stars, or a neutron star and a black hole.

The so-called long-duration gamma-ray bursts produce a total energy output of about 1044 joules (as much energy as the Sun will produce in its entire life-time) but in a period of only 20 to 40 seconds. Gamma rays are approximately 50% of the total energy output. The leading hypotheses for the mechanism of production of these highest-known intensity beams of radiation, are inverse Compton scattering and synchrotron radiation from high-energy charged particles. These processes occur as relativistic charged particles leave the region of the event horizon of a newly formed black hole created during supernova explosion. The beam of particles moving at relativistic speeds are focused for a few tens of seconds by the magnetic field of the exploding hypernova. The fusion explosion of the hypernova drives the energetics of the process. If the narrowly directed beam happens to be pointed toward the Earth, it shines at gamma ray frequencies with such intensity, that it can be detected even at distances of up to 10 billion light years, which is close to the edge of the visible universe.

Properties

Penetration of matter

Alpha radiation consists of helium nuclei and is readily stopped by a sheet of paper. Beta radiation, consisting of electrons or positrons, is stopped by an aluminium plate, but gamma radiation requires shielding by dense material such as lead or concrete.

Due to their penetrating nature, gamma rays require large amounts of shielding mass to reduce them to levels which are not harmful to living cells, in contrast to alpha particles, which can be stopped by paper or skin, and beta particles, which can be shielded by thin aluminium. Gamma rays are best absorbed by materials with high atomic numbers (Z) and high density, which contribute to the total stopping power. Because of this, a lead (high Z) shield is 20–30% better as a gamma shield than an equal mass of another low-Z shielding material, such as aluminium, concrete, water, or soil; lead's major advantage is not in lower weight, but rather its compactness due to its higher density. Protective clothing, goggles and respirators can protect from internal contact with or ingestion of alpha or beta emitting particles, but provide no protection from gamma radiation from external sources.

The higher the energy of the gamma rays, the thicker the shielding made from the same shielding material is required. Materials for shielding gamma rays are typically measured by the thickness required to reduce the intensity of the gamma rays by one half (the half value layer or HVL). For example, gamma rays that require 1 cm (0.4 inch) of lead to reduce their intensity by 50% will also have their intensity reduced in half by 4.1 cm of granite rock, 6 cm (2.5 inches) of concrete, or 9 cm (3.5 inches) of packed soil. However, the mass of this much concrete or soil is only 20–30% greater than that of lead with the same absorption capability. Depleted uranium is used for shielding in portable gamma ray sources, but here the savings in weight over lead are larger, as a portable source is very small relative to the required shielding, so the shielding resembles a sphere to some extent. The volume of a sphere is dependent on the cube of the radius; so a source with its radius cut in half will have its volume (and weight) reduced by a factor of eight, which will more than compensate for uranium's greater density (as well as reducing bulk). In a nuclear power plant, shielding can be provided by steel and concrete in the pressure and particle containment vessel, while water provides a radiation shielding of fuel rods during storage or transport into the reactor core. The loss of water or removal of a "hot" fuel assembly into the air would result in much higher radiation levels than when kept under water.

Matter interaction

The total absorption coefficient of aluminium (atomic number 13) for gamma rays, plotted versus gamma energy, and the contributions by the three effects. As is usual, the photoelectric effect is largest at low energies, Compton scattering dominates at intermediate energies, and pair production dominates at high energies.
The total absorption coefficient of lead (atomic number 82) for gamma rays, plotted versus gamma energy, and the contributions by the three effects. Here, the photoelectric effect dominates at low energy. Above 5 MeV, pair production starts to dominate.

When a gamma ray passes through matter, the probability for absorption is proportional to the thickness of the layer, the density of the material, and the absorption cross section of the material. The total absorption shows an exponential decrease of intensity with distance from the incident surface:

where x is the thickness of the material from the incident surface, μ= nσ is the absorption coefficient, measured in cm−1, n the number of atoms per cm3 of the material (atomic density) and σ the absorption cross section in cm2.

As it passes through matter, gamma radiation ionizes via three processes:

  • The photoelectric effect: This describes the case in which a gamma photon interacts with and transfers its energy to an atomic electron, causing the ejection of that electron from the atom. The kinetic energy of the resulting photoelectron is equal to the energy of the incident gamma photon minus the energy that originally bound the electron to the atom (binding energy). The photoelectric effect is the dominant energy transfer mechanism for X-ray and gamma ray photons with energies below 50 keV (thousand electronvolts), but it is much less important at higher energies.
  • Compton scattering: This is an interaction in which an incident gamma photon loses enough energy to an atomic electron to cause its ejection, with the remainder of the original photon's energy emitted as a new, lower energy gamma photon whose emission direction is different from that of the incident gamma photon, hence the term "scattering". The probability of Compton scattering decreases with increasing photon energy. It is thought to be the principal absorption mechanism for gamma rays in the intermediate energy range 100 keV to 10 MeV. It is relatively independent of the atomic number of the absorbing material, which is why very dense materials like lead are only modestly better shields, on a per weight basis, than are less dense materials.
  • Pair production: This becomes possible with gamma energies exceeding 1.02 MeV, and becomes important as an absorption mechanism at energies over 5 MeV (see illustration at right, for lead). By interaction with the electric field of a nucleus, the energy of the incident photon is converted into the mass of an electron-positron pair. Any gamma energy in excess of the equivalent rest mass of the two particles (totaling at least 1.02 MeV) appears as the kinetic energy of the pair and in the recoil of the emitting nucleus. At the end of the positron's range, it combines with a free electron, and the two annihilate, and the entire mass of these two is then converted into two gamma photons of at least 0.51 MeV energy each (or higher according to the kinetic energy of the annihilated particles).

The secondary electrons (and/or positrons) produced in any of these three processes frequently have enough energy to produce much ionization themselves.

Additionally, gamma rays, particularly high energy ones, can interact with atomic nuclei resulting in ejection of particles in photodisintegration, or in some cases, even nuclear fission (photofission).

Light interaction

High-energy (from 80 GeV to ~10 TeV) gamma rays arriving from far-distant quasars are used to estimate the extragalactic background light in the universe: The highest-energy rays interact more readily with the background light photons and thus the density of the background light may be estimated by analyzing the incoming gamma ray spectra.

Gamma spectroscopy

Gamma spectroscopy is the study of the energetic transitions in atomic nuclei, which are generally associated with the absorption or emission of gamma rays. As in optical spectroscopy (see Franck–Condon effect) the absorption of gamma rays by a nucleus is especially likely (i.e., peaks in a "resonance") when the energy of the gamma ray is the same as that of an energy transition in the nucleus. In the case of gamma rays, such a resonance is seen in the technique of Mössbauer spectroscopy. In the Mössbauer effect the narrow resonance absorption for nuclear gamma absorption can be successfully attained by physically immobilizing atomic nuclei in a crystal. The immobilization of nuclei at both ends of a gamma resonance interaction is required so that no gamma energy is lost to the kinetic energy of recoiling nuclei at either the emitting or absorbing end of a gamma transition. Such loss of energy causes gamma ray resonance absorption to fail. However, when emitted gamma rays carry essentially all of the energy of the atomic nuclear de-excitation that produces them, this energy is also sufficient to excite the same energy state in a second immobilized nucleus of the same type.

Applications

Gamma-ray image of a truck with two stowaways taken with a VACIS (vehicle and container imaging system)

Gamma rays provide information about some of the most energetic phenomena in the universe; however, they are largely absorbed by the Earth's atmosphere. Instruments aboard high-altitude balloons and satellites missions, such as the Fermi Gamma-ray Space Telescope, provide our only view of the universe in gamma rays.

Gamma-induced molecular changes can also be used to alter the properties of semi-precious stones, and is often used to change white topaz into blue topaz.

Non-contact industrial sensors commonly use sources of gamma radiation in refining, mining, chemicals, food, soaps and detergents, and pulp and paper industries, for the measurement of levels, density, and thicknesses. Gamma-ray sensors are also used for measuring the fluid levels in water and oil industries. Typically, these use Co-60 or Cs-137 isotopes as the radiation source.

In the US, gamma ray detectors are beginning to be used as part of the Container Security Initiative (CSI). These machines are advertised to be able to scan 30 containers per hour.

Gamma radiation is often used to kill living organisms, in a process called irradiation. Applications of this include the sterilization of medical equipment (as an alternative to autoclaves or chemical means), the removal of decay-causing bacteria from many foods and the prevention of the sprouting of fruit and vegetables to maintain freshness and flavor.

Despite their cancer-causing properties, gamma rays are also used to treat some types of cancer, since the rays also kill cancer cells. In the procedure called gamma-knife surgery, multiple concentrated beams of gamma rays are directed to the growth in order to kill the cancerous cells. The beams are aimed from different angles to concentrate the radiation on the growth while minimizing damage to surrounding tissues.

Gamma rays are also used for diagnostic purposes in nuclear medicine in imaging techniques. A number of different gamma-emitting radioisotopes are used. For example, in a PET scan a radiolabeled sugar called fluorodeoxyglucose emits positrons that are annihilated by electrons, producing pairs of gamma rays that highlight cancer as the cancer often has a higher metabolic rate than the surrounding tissues. The most common gamma emitter used in medical applications is the nuclear isomer technetium-99m which emits gamma rays in the same energy range as diagnostic X-rays. When this radionuclide tracer is administered to a patient, a gamma camera can be used to form an image of the radioisotope's distribution by detecting the gamma radiation emitted (see also SPECT). Depending on which molecule has been labeled with the tracer, such techniques can be employed to diagnose a wide range of conditions (for example, the spread of cancer to the bones via bone scan).

Health effects

Gamma rays cause damage at a cellular level and are penetrating, causing diffuse damage throughout the body. However, they are less ionising than alpha or beta particles, which are less penetrating.

Low levels of gamma rays cause a stochastic health risk, which for radiation dose assessment is defined as the probability of cancer induction and genetic damage. High doses produce deterministic effects, which is the severity of acute tissue damage that is certain to happen. These effects are compared to the physical quantity absorbed dose measured by the unit gray (Gy).

Body response

When gamma radiation breaks DNA molecules, a cell may be able to repair the damaged genetic material, within limits. However, a study of Rothkamm and Lobrich has shown that this repair process works well after high-dose exposure but is much slower in the case of a low-dose exposure.

Risk assessment

The natural outdoor exposure in the United Kingdom ranges from 0.1 to 0.5 µSv/h with significant increase around known nuclear and contaminated sites. Natural exposure to gamma rays is about 1 to 2 mSv per year, and the average total amount of radiation received in one year per inhabitant in the USA is 3.6 mSv. There is a small increase in the dose, due to naturally occurring gamma radiation, around small particles of high atomic number materials in the human body caused by the photoelectric effect.

By comparison, the radiation dose from chest radiography (about 0.06 mSv) is a fraction of the annual naturally occurring background radiation dose.[21] A chest CT delivers 5 to 8 mSv. A whole-body PET/CT scan can deliver 14 to 32 mSv depending on the protocol. The dose from fluoroscopy of the stomach is much higher, approximately 50 mSv (14 times the annual background).

An acute full-body equivalent single exposure dose of 1 Sv (1000 mSv), or 1 Gy, will cause mild symptoms of acute radiation sickness, such as nausea and vomiting; and a dose of 2.0–3.5 Sv (2.0–3.5 Gy) causes more severe symptoms (i.e. nausea, diarrhea, hair loss, hemorrhaging, and inability to fight infections), and will cause death in a sizable number of cases —- about 10% to 35% without medical treatment. A dose of 5 Sv (5 Gy) is considered approximately the LD50 (lethal dose for 50% of exposed population) for an acute exposure to radiation even with standard medical treatment. A dose higher than 5 Sv (5 Gy) brings an increasing chance of death above 50%. Above 7.5–10 Sv (7.5–10 Gy) to the entire body, even extraordinary treatment, such as bone-marrow transplants, will not prevent the death of the individual exposed (see radiation poisoning). (Doses much larger than this may, however, be delivered to selected parts of the body in the course of radiation therapy.)

For low-dose exposure, for example among nuclear workers, who receive an average yearly radiation dose of 19 mSv, the risk of dying from cancer (excluding leukemia) increases by 2 percent. For a dose of 100 mSv, the risk increase is 10 percent. By comparison, risk of dying from cancer was increased by 32 percent for the survivors of the atomic bombing of Hiroshima and Nagasaki.

Units of measurement and exposure

The following table shows radiation quantities in SI and non-SI units:

Ionizing radiation related quantities view  talk  edit
Quantity Unit Symbol Derivation Year SI equivalent
Activity (A) becquerel Bq s−1 1974 SI unit
curie Ci 3.7 × 1010 s−1 1953 3.7×1010 Bq
rutherford Rd 106 s−1 1946 1,000,000 Bq
Exposure (X) coulomb per kilogram C/kg C⋅kg−1 of air 1974 SI unit
röntgen R esu / 0.001293 g of air 1928 2.58 × 10−4 C/kg
Absorbed dose (D) gray Gy J⋅kg−1 1974 SI unit
erg per gram erg/g erg⋅g−1 1950 1.0 × 10−4 Gy
rad rad 100 erg⋅g−1 1953 0.010 Gy
Equivalent dose (H) sievert Sv J⋅kg−1 × WR 1977 SI unit
röntgen equivalent man rem 100 erg⋅g−1 × WR 1971 0.010 Sv
Effective dose (E) sievert Sv J⋅kg−1 × WR × WT 1977 SI unit
röntgen equivalent man rem 100 erg⋅g−1 × WR × WT 1971 0.010 Sv

The measure of the ionizing effect of gamma and X-rays in dry air is called the exposure, for which a legacy unit, the röntgen was used from 1928. This has been replaced by kerma, now mainly used for instrument calibration purposes but not for received dose effect. The effect of gamma and other ionizing radiation on living tissue is more closely related to the amount of energy deposited in tissue rather than the ionisation of air, and replacement radiometric units and quantities for radiation protection have been defined and developed from 1953 onwards. These are:

  • The gray (Gy), is the SI unit of absorbed dose, which is the amount of radiation energy deposited in the irradiated material. For gamma radiation this is numerically equivalent to equivalent dose measured by the sievert, which indicates the stochastic biological effect of low levels of radiation on human tissue. The radiation weighting conversion factor from absorbed dose to equivalent dose is 1 for gamma, whereas alpha particles have a factor of 20, reflecting their greater ionising effect on tissue.
  • The rad is the deprecated CGS unit for absorbed dose and the rem is the deprecated CGS unit of equivalent dose, used mainly in the USA.

Distinction from X-rays

In practice, gamma ray energies overlap with the range of X-rays, especially in the higher-frequency region referred to as "hard" X-rays. This depiction follows the older convention of distinguishing by wavelength.

The conventional distinction between X-rays and gamma rays has changed over time. Originally, the electromagnetic radiation emitted by X-ray tubes almost invariably had a longer wavelength than the radiation (gamma rays) emitted by radioactive nuclei. Older literature distinguished between X- and gamma radiation on the basis of wavelength, with radiation shorter than some arbitrary wavelength, such as 10−11 m, defined as gamma rays. Since the energy of photons is proportional to their frequency and inversely proportional to wavelength, this past distinction between X-rays and gamma rays can also be thought of in terms of its energy, with gamma rays considered to be higher energy electromagnetic radiation than are X-rays.

However, since current artificial sources are now able to duplicate any electromagnetic radiation that originates in the nucleus, as well as far higher energies, the wavelengths characteristic of radioactive gamma ray sources vs. other types now completely overlap. Thus, gamma rays are now usually distinguished by their origin: X-rays are emitted by definition by electrons outside the nucleus, while gamma rays are emitted by the nucleus. Exceptions to this convention occur in astronomy, where gamma decay is seen in the afterglow of certain supernovas, but radiation from high energy processes known to involve other radiation sources than radioactive decay is still classed as gamma radiation.

The Moon as seen by the Compton Gamma Ray Observatory, in gamma rays of greater than 20 MeV. These are produced by cosmic ray bombardment of its surface. The Sun, which has no similar surface of high atomic number to act as target for cosmic rays, cannot usually be seen at all at these energies, which are too high to emerge from primary nuclear reactions, such as solar nuclear fusion (though occasionally the Sun produces gamma rays by cyclotron-type mechanisms, during solar flares). Gamma rays typically have higher energy than X-rays.

For example, modern high-energy X-rays produced by linear accelerators for megavoltage treatment in cancer often have higher energy (4 to 25 MeV) than do most classical gamma rays produced by nuclear gamma decay. One of the most common gamma ray emitting isotopes used in diagnostic nuclear medicine, technetium-99m, produces gamma radiation of the same energy (140 keV) as that produced by diagnostic X-ray machines, but of significantly lower energy than therapeutic photons from linear particle accelerators. In the medical community today, the convention that radiation produced by nuclear decay is the only type referred to as "gamma" radiation is still respected.

Due to this broad overlap in energy ranges, in physics the two types of electromagnetic radiation are now often defined by their origin: X-rays are emitted by electrons (either in orbitals outside of the nucleus, or while being accelerated to produce bremsstrahlung-type radiation), while gamma rays are emitted by the nucleus or by means of other particle decays or annihilation events. There is no lower limit to the energy of photons produced by nuclear reactions, and thus ultraviolet or lower energy photons produced by these processes would also be defined as "gamma rays". The only naming-convention that is still universally respected is the rule that electromagnetic radiation that is known to be of atomic nuclear origin is always referred to as "gamma rays", and never as X-rays. However, in physics and astronomy, the converse convention (that all gamma rays are considered to be of nuclear origin) is frequently violated.

In astronomy, higher energy gamma and X-rays are defined by energy, since the processes that produce them may be uncertain and photon energy, not origin, determines the required astronomical detectors needed. High-energy photons occur in nature that are known to be produced by processes other than nuclear decay but are still referred to as gamma radiation. An example is "gamma rays" from lightning discharges at 10 to 20 MeV, and known to be produced by the bremsstrahlung mechanism.

Another example is gamma-ray bursts, now known to be produced from processes too powerful to involve simple collections of atoms undergoing radioactive decay. This is part and parcel of the general realization that many gamma rays produced in astronomical processes result not from radioactive decay or particle annihilation, but rather in non-radioactive processes similar to X-rays. Although the gamma rays of astronomy often come from non-radioactive events, a few gamma rays in astronomy are specifically known to originate from gamma decay of nuclei (as demonstrated by their spectra and emission half life). A classic example is that of supernova SN 1987A, which emits an "afterglow" of gamma-ray photons from the decay of newly made radioactive nickel-56 and cobalt-56. Most gamma rays in astronomy, however, arise by other mechanisms.

Mutation breeding

From Wikipedia, the free encyclopedia

Mutation breeding, sometimes referred to as "variation breeding", is the process of exposing seeds to chemicals, radiation, or enzymes in order to generate mutants with desirable traits to be bred with other cultivars. Plants created using mutagenesis are sometimes called mutagenic plants or mutagenic seeds.

From 1930 to 2014 more than 3200 mutagenic plant varieties were released that have been derived either as direct mutants (70%) or from their progeny (30%). Crop plants account for 75% of released mutagenic species with the remaining 25% ornamentals or decorative plants. However, although the FAO/IAEA reported in 2014 that over 1,000 mutant varieties of major staple crops were being grown worldwide, it is unclear how many of these varieties are currently used in agriculture or horticulture around the world, as these seeds are not always identified or labeled as having a mutagenic provenance.

History

According to garden historian Paige Johnson:

After WWII, there was a concerted effort to find 'peaceful' uses for atomic energy. One of the ideas was to bombard plants with radiation and produce lots of mutations, some of which, it was hoped, would lead to plants that bore more heavily or were disease or cold-resistant or just had unusual colors. The experiments were mostly conducted in giant gamma gardens on the grounds of national laboratories in the US but also in Europe and countries of the [then-]USSR.

Processes

There are different kinds of mutagenic breeding such as using chemical mutagens like ethyl methanesulfonate and dimethyl sulfate, radiation or transposons to generate mutants. Mutation breeding is commonly used to produce traits in crops such as larger seeds, new colors, or sweeter fruits, that either cannot be found in nature or have been lost during evolution.

Radiation

Exposing plants to radiation is sometimes called radiation breeding and is a sub class of mutagenic breeding. Radiation breeding was discovered in the 1920s when Lewis Stadler of the University of Missouri used X-rays on maize and barley. In the case of barley, the resulting plants were white, yellow, pale yellow and some had white stripes. In 1928, Stadler first published his findings on radiation-induced mutagenesis in plants. During the period 1930–2004, radiation-induced mutant varieties were developed primarily using gamma rays (64%) and X-rays (22%).

Radiation breeding may take place in atomic gardens; and seeds have been sent into orbit in order to expose them to more cosmic radiation.

Ultraviolet has been used, for example to produce knockouts for the investigation of virulence mechanisms of plant pathogens.

Chemicals

High rates of chromosome aberrations resulting from ionizing radiation and the accompanied detrimental effects made researchers look for alternate sources for inducing mutations. As a result, an array of chemical mutagens has been discovered. The most widely used chemical mutagens are alkylating agents. Ethyl methanesulfonate (EMS) is the most popular because of its effectiveness and ease of handling, especially its detoxification through hydrolysis for disposal. Nitroso compounds are the other alkylating agents widely used, but they are light-sensitive and more precautions need to be taken because of their higher volatility. EMS has become a commonly used mutagen for developing large numbers of mutants for screening such as in developing TILLING populations. Although many chemicals are mutagens, only few have been used in practical breeding as the doses need to be optimised and also because the effectiveness is not high in plants for many.

Restriction endonucleases

Interest in the use of bacterial restriction endonucleases (RE) - for example Fok1 and CRISPR/Cas9 - to study double-stranded breaks in plant DNA began in the mid-nineties. These breaks in DNA, otherwise known as DSBs, were found to be the source of much chromosomal damage in eukaryotes, causing mutations in plant varieties. REs induce a result on plant DNA similar to that of ionizing radiation or radiomimetic chemicals. Blunt ended breaks in the DNA, unlike sticky ended breaks, were found to produce more variations in chromosomal damage, making them the more useful type of break for mutation breeding. While the connection of REs to chromosomal aberrations is mostly limited to research on mammalian DNA, success in mammalian studies caused scientists to conduct more studies of RE-induced chromosomal and DNA damage on barley genomes. Due to restriction endonucleases' ability to facilitate damage in chromosomes and DNA, REs have the capability of being used as a new method of mutagenesis to promote the proliferation of mutated plant varieties.

Space-breeding

The ability of plants to develop and thrive is dependent on conditions such as microgravity and cosmic radiation in space. China has been experimenting with this theory by sending seeds into space, testing to see if space flights will cause genetic mutations. Since 1987, China has cultivated 66 mutant varieties from space through their space-breeding program. Chromosomal aberrations greatly increased when seeds were sent into aerospace compared to their earth-bound counterparts. The effect of space flight on seeds depends on their species and variety. For example, space-bred wheat saw a large growth in seed germination in compared to its Earth-bound control, but space-bred rice had no visible advantage compared to its control. For the varieties that were positively mutated by space flight, their growth potential exceeded that of not only their Earth-grown counterparts, but also their irradiated counterparts on Earth. Compared to traditional mutagenic techniques, space-bred mutations have greater efficacy in that they experience positive effects on their first generation of mutation, whereas irradiated crops often see no advantageous mutations in their first generations. Though multiple experiments have shown the positive effects of space flight on seed mutation, there is no clear connection as to what aspect of aerospace has produced such advantageous mutations. There is much speculation around cosmic radiation being the source of chromosomal aberrations, but so far, there has been no concrete evidence of such connection. Though China's space-breeding program has been shown to be very successful, the program requires a large budget and technological support that many other countries are either unwilling or unable to provide, meaning this program is unfeasible outside of China. Due to such restraints, scientists have been trying to replicate space condition on Earth in order to promote the same expedient space-born mutations on Earth. One such replication is a magnetic field-free space (MF), which produces an area with a weaker magnetic field than that of Earth. MF treatment produced mutagenic results, and has been used to cultivate new mutant varieties of rice and alfalfa. Other replications of space conditions include irradiation of seeds by a heavy 7 Li-ion beam or mixed high-energy particles. These space-bred varieties are already being introduced to the public. In 2011, during the National Lotus Flowers Exhibition in China, a mutant lotus, called the "Outer Space Sun", was shown at the flower show.

Ion beam technology

Ion beams mutate DNA by deleting multiple bases from the genome. Compared to traditional sources of radiation, like gamma rays and X-rays, ion beams have been shown to cause more severe breaks in DNA that are more difficult to weave back together, causing the change in DNA to be more drastic than changes caused by traditional irradiation. Ion beams change DNA in a manner that makes it look vastly different than its original makeup, more so than when traditional irradiation techniques are used. Most experimentation, using ion beam technology, has been conducted in Japan. Notable facilities using this technology are TIARA of the Japan Atomic Energy Agency, RIKEN Accelerator Research Facility, and various other Japanese institutions. During the process of ion beam radiation, seeds are wedged between two kapton films and irradiated for roughly two minutes. Mutation frequencies are notably higher for ion beam radiation compared to electron radiation, and the mutation spectrum is broader for ion beam radiation compared to gamma ray radiation. The broader mutation spectrum was revealed through the largely varied amount of flower phenotypes produced by ion beams. Flowers mutated by the ion beams exhibited a variety of colors, patterns, and shapes. Through ion beam radiation, new varieties of plants have been cultivated. These plants had the characteristics of being ultraviolet light-B resistant, disease resistant, and chlorophyll-deficient. Ion beam technology has been used in the discovery of new genes responsible for the creation of more robust plants, but its most prevalent use is commercially for producing new flower phenotypes, like striped chrysanthemums.

Mature pollen treated with gamma radiation

Gamma radiation is used on mature rice pollen to produce parent plants used for crossing. The mutated traits in the parent plants are able to be inherited by their offspring plants. Because rice pollen has a very short lifespan, researchers had to blast gamma rays at cultured spikes from rice plants. Through experimentation, it was revealed that there was a greater variety of mutation in irradiated pollen rather than irradiated dry seeds. Pollen treated with 46Gy of gamma radiation showed an increase in grain size overall and other useful variations. Typically, the length of each grain was longer after the crossing of irradiated parent rice plants. The rice progeny also exhibited a less chalky visage, improving on the appearance of the parent rice plants. This technique was used to develop two new rice cultivars, Jiaohezaozhan and Jiafuzhan, in China. Along with facilitating the creation of these two rice cultivars, the irradiation of mature rice pollen has produced roughly two hundred mutant rice lines. Each of these lines produce rice grains of both a higher quality and larger size. The mutations produced by this technique vary with each generation, meaning further breeding of these mutated plants could produce new mutations. Traditionally, gamma radiation is used on solely adult plants, and not on pollen. The irradiation of mature pollen allows mutant plants to grow without being in direct contact with gamma radiation. This discovery is in contrast to what was previously believed about gamma radiation: that it could only elicit mutations in plants and not pollen.

Comparison to other techniques

In the debate over genetically modified foods, the use of transgenic processes is often compared and contrasted with mutagenic processes. While the abundance and variation of transgenic organisms in human food systems, and their effect on agricultural biodiversity, ecosystem health and human health is somewhat well documented, mutagenic plants and their role on human food systems is less well known, with one journalist writing "Though poorly known, radiation breeding has produced thousands of useful mutants and a sizable fraction of the world's crops...including varieties of rice, wheat, barley, pears, peas, cotton, peppermint, sunflowers, peanuts, grapefruit, sesame, bananas, cassava and sorghum." In Canada crops generated by mutation breeding face the same regulations and testing as crops obtained by genetic engineering. Mutagenic varieties tend to be made freely available for plant breeding, in contrast to many commercial plant varieties or germplasm that increasingly have restrictions on their use such as terms of use, patents and proposed genetic user restriction technologies and other intellectual property regimes and modes of enforcement.

Unlike genetically modified crops, which typically involve the insertion of one or two target genes, plants developed via mutagenic processes with random, multiple and unspecific genetic changes have been discussed as a concern but are not prohibited by any nation's organic standards. Reports from the US National Academy of Sciences state that there is no scientific justification for regulating genetic engineered crops while not doing so for mutation breeding crops.

Several organic food and seed companies promote and sell certified organic products that were developed using both chemical and nuclear mutagenesis. Several certified organic brands, whose companies support strict labeling or outright bans on GMO-crops, market their use of branded wheat and other varietal strains which were derived from mutagenic processes without any reference to this genetic manipulation. These organic products range from mutagenic barley and wheat ingredient used in organic beers to mutagenic varieties of grapefruits sold directly to consumers as organic.

Release by nation

As of 2011 the percentage of all mutagenic varieties released globally, by country, were:

Notable varieties per country include:

 Argentina

  • Colorado Irradiado groundnut (mutant created with X-rays; high fat content and yield, 80% of groundnuts grown in Argentina in the 1980s was Colorado Irradiado)
  • Puita INTA-CL rice mutant (herbicide resistance and good yield; also grown in Bolivia, Brazil, Costa Rica and Paraguay)
 Australia
  • Amaroo rice mutant variety (60-70% of rice grown in Australia was Amaroo in 2001)
 Bangladesh

  • Binasail, Iratom-24 and Binadhan-6 rice mutants
  • Binamoog-5 mung bean mutant variety
 Cuba

  • Maybel tomato mutant (excellent drought resistance)
  • GINES rice mutant (created using proton radiation; grows well in salty conditions)
 People's Republic of China

  • Henong series soybean mutants
  • Jiahezazhan and Jiafuzhan rice (mutations obtained by pollen irradiation; high yield and quality, very adaptable, resistant to plant hopper and blast)
  • Lumian Number 1 cotton
  • Purple Orchard 3 Sweet potato
  • Tiefeng 18 soybean
  • Yangdao Number 6 rice
  • Yangmai 156 wheat
  • Zhefu 802 rice mutant (irradiated with gamma rays; resistant to rice blast, good yield even in poor conditions, the most planted rice variety between 1986-1994)
  • 26Zhaizao indica rice mutant (created with gamma rays)

 Czech Republic

  • Diamant barley (high yield, short height mutant created with X-Rays)
 Egypt

  • Giza 176 and Sakha 101 high yield rice mutants
 Finland

  • Balder J barley mutant (better drought resistance, yield and sprouting)
  • Puhti and Ryhti stiff straw oat mutants
 France

  • High oleic sunflowers (covering more than 50 % of the sunflower acreage)
 Germany

  • Trumpf barley
 Ghana

  • Tek bankye mutant cassava (good poundability and increased dry matter content)
 India

  • Co-4, Pant Mung-2, and TAP mung bean mutants
  • MA-9 cotton - the world's first mutant cotton, released in 1948 (X-ray radiation; drought tolerance, high yielding)
  • PNR-381 Rice
  • Pusa 408 (Ajay), Pusa 413 (Atul), Pusa 417 (Girnar), and Pusa 547 chickpea mutants (resistant to Ascochyta blight and wilt diseases, and have high yields)
  • Sharbati Sonora wheat
  • Tau-1, MUM 2, BM 4, LGG 407, LGG 450, Co4, Dhauli (TT9E) and Pant moong-1 blackgram (YMC, (Yellow mosaic virus) resistance)
  • TG24 and TG37 groundnut mutants
 Italy

  • Durum wheat (especially Creso mutant, created with thermal neutrons)
 Japan

  • Osa Gold Pear (disease resistance) 
  • Most rice varieties grown in Japan have the sd1 mutant allele from the Reimei rice variety
 Myanmar

  • Shwewartun rice mutant (created by irradiating IR5 rice to give better yield, grain quality and earlier maturity)
 Pakistan

  • Basmati 370 short height rice mutant
  • NIAB-78 cotton mutant (high yielding, heat tolerant, early maturing)
  • CM-72 chickpea mutant (created with 150Gy of gamma rays; high yielding, blight resistant)
  • NM-28 mungbean mutant (short height, uniform and early maturing, high seed yield)
  • NIAB Masoor 2006 lentil mutant (created with 200Gy of radiation; early maturing, high yield, resistant to disease)
 Peru

  • UNA La Molina 95 barley mutant (developed in 1995 for growing above 3,000 m)
  • Centenario Amarinth "kiwicha" mutant (high quality grain and exported as a certified organic product)
  • Centenario II barley mutant (developed for growing in the Andean highlands with high yield, high quality flour and tolerance to hail)
 Sudan

  • Albeely banana mutant (better quality, high yield and better stand)
 Thailand

  • RD15 and RD6 aromatic indica rice mutants (created with gamma rays and released in 1977-8; RD 15 is early ripening, RD6 has a valuable glutinous endosperm). Thailand is the biggest exporter of aromatic rice in the world
 United Kingdom

  • Golden Promise barley (semi-dwarf, salt tolerant mutant created with gamma rays) Is used to make beer and whisky
 United States

  • Calrose 76 Rice (short height rice induced with gamma rays)
  • Luther and Pennrad barley (high yield mutant varieties; Pennrad also resistant to winter)
  • Murray Mitcham Peppermint (Verticillium wilt tolerance)
  • Sanilac bean (X-ray radiation; high yielding mutant - also the Gratiot and Sea-way bean varieties were cross-bred from Sanilac)
  • Stadler wheat (high yield mutant with resistance to loose smut and leaf rust and earlier maturity)
  • Star Ruby and Rio red varieties of the Rio Star Grapefruit (created using thermal neutron techniques)
  • Todd's Mitcham Peppermint (Verticillium wilt tolerance)
 Vietnam

  • VND 95-20, VND-99-1 and VN121 rice mutants (increased yield, improved quality, resistance to disease and pests)
  • DT84, DT96, DT99 and DT 2008 soybean mutants (developed using gamma rays to grow three crops a year, tolerance to heat and cold and resistance to disease)

In 2014, it was reported that 17 rice mutant varieties, 10 soybean, two maize and one chrysanthemum mutant varieties had been officially released to Vietnamese farmers. 15% of rice and 50% of soybean was produced from mutant varieties.

Authorship of the Bible

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