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Monday, July 1, 2019

History of alcoholic drinks

From Wikipedia, the free encyclopedia

Total recorded alcohol per capita consumption (15+), in litres of pure alcohol
 
Purposeful production of alcoholic drinks is common and often reflects cultural and religious peculiarities as much as geographical and sociological conditions. 

Discovery of late Stone Age jugs suggest that intentionally fermented beverages existed at least as early as the Neolithic period (c. 10000 BC).

Archaeological record

The ability to metabolize alcohol likely predates humanity with primates eating fermenting fruit.

The world's oldest brewery was discovered in 2018 in a prehistoric burial site in a cave near Haifa in Israel. Researchers have found residue of 13,000-year-old beer that they think might have been used for ritual feasts to honor the dead. The traces of a wheat-and-barley-based alcohol were found in stone mortars carved into the cave floor. It had been thought that beer-making originated in Babylon 5000 years ago. This new discovery precedes that by 8000 years.

As early as 7000 BC, chemical analysis of jars from the neolithic village Jiahu in the Henan province of northern China revealed traces of a mixed fermented beverage. According to a study published in the Proceedings of the National Academy of Sciences in December 2004, chemical analysis of the residue confirmed that a fermented drink made of grapes, hawthorn berries, honey, and rice was being produced in 7000–6650 BC. This is approximately the time when barley beer and grape wine were beginning to be made in the Middle East.

Evidence of alcoholic beverages has also been found dating from 5400-5000 BC in Hajji Firuz Tepe in Iran, 3150 BC in ancient Egypt, 3000 BC in Babylon, 2000 BC in pre-Hispanic Mexico and 1500 BC in Sudan. According to Guinness, the earliest firm evidence of wine production dates back to 6000 BC in Georgia.

The medicinal use of alcohol was mentioned in Sumerian and Egyptian texts dating from about 2100 BC. The Hebrew Bible recommends giving alcoholic drinks to those who are dying or depressed, so that they can forget their misery (Proverbs 31:6-7). 

Wine was consumed in Classical Greece at breakfast or at symposia, and in the 1st century BC it was part of the diet of most Roman citizens. Both the Greeks and the Romans generally drank diluted wine (the strength varying from 1 part wine and 1 part water, to 1 part wine and 4 parts water). 

In Europe during the Middle Ages, beer, often of very low strength, was an everyday drink for all classes and ages of people. A document from that time mentions nuns having an allowance of six pints of ale each day. Cider and pomace wine were also widely available; grape wine was the prerogative of the higher classes. 

By the time the Europeans reached the Americas in the 15th century, several native civilizations had developed alcoholic beverages. According to a post-conquest Aztec document, consumption of the local "wine" (pulque) was generally restricted to religious ceremonies but was freely allowed to those who were older than 70 years. The natives of South America produced a beer-like beverage from cassava or maize, which had to be chewed before fermentation in order to turn the starch into sugar. (Beverages of this kind are known today as cauim or chicha.) This chewing technique was also used in ancient Japan to make sake from rice and other starchy crops.

Ancient period

Ancient China

The earliest evidence of wine was found in what is now China, where jars from Jiahu which date to about 7000 BC were discovered. This early rice wine was produced by fermenting rice, honey, and fruit. What later developed into Chinese civilization grew up along the more northerly Yellow River and fermented a kind of huangjiu from millet. The Zhou attached great importance to alcohol and ascribed the loss of the mandate of Heaven by the earlier Xia and Shang as largely due to their dissolute and alcoholic emperors. An edict ascribed to c. 1116 BC makes it clear that the use of alcohol in moderation was believed to be prescribed by heaven.

Unlike the traditions in Europe and the Middle East, China abandoned the production of grape wine before the advent of writing and, under the Han, abandoned beer in favor of huangjiu and other forms of rice wine. These naturally fermented to a strength of about 20% ABV; they were usually consumed warmed and frequently flavored with additives as part of traditional Chinese medicine. They considered it spiritual food and extensive documentary evidence attests to the important role it played in religious life. "In ancient times people always drank when holding a memorial ceremony, offering sacrifices to gods or their ancestors, pledging resolution before going into battle, celebrating victory, before feuding and official executions, for taking an oath of allegiance, while attending the ceremonies of birth, marriage, reunions, departures, death, and festival banquets." Marco Polo's 14th century record indicates grain and rice wine were drunk daily and were one of the treasury's biggest sources of income. 

Alcoholic beverages were widely used in all segments of Chinese society, were used as a source of inspiration, were important for hospitality, were considered an antidote for fatigue, and were sometimes misused. Laws against making wine were enacted and repealed forty-one times between 1100 BC and AD 1400. However, a commentator writing around 650 BC asserted that people "will not do without beer. To prohibit it and secure total abstinence from it is beyond the power even of sages. Hence, therefore, we have warnings on the abuse of it."

The Chinese may have independently developed the process of distillation in the early centuries of the Common Era, during the Eastern Han dynasty.

Ancient Persia (or Ancient Iran)

A major step forward in our understanding of Neolithic winemaking came from the analysis of a yellowish residue excavated by Mary M. Voigt at the site of Hajji Firuz Tepe in the northern Zagros Mountains of Iran. The jar that once contained wine, with a volume of about 9 liters (2.5 gallons) was found together with five similar jars embedded in the earthen floor along one wall of a "kitchen" of a Neolithic mudbrick building, dated to c. 5400-5000 BC. In such communities, winemaking was the best technology they had for storing highly perishable grapes, although whether the resulting beverage was intended for intoxication as well as nourishment is not known.

Ancient Egypt

Brewing dates from the beginning of civilization in ancient Egypt, and alcoholic beverages were very important at that time. Egyptian brewing began in the city of Heirakonpolis around 3400 BC; its ruins contain the remains of the world’s oldest brewery, which was capable of producing up to three hundred gallons per day of beer. Symbolic of this is the fact that while many gods were local or familial, Osiris was worshiped throughout the entire country. Osiris was believed to be the god of the dead, of life, of vegetable regeneration, and of wine.

Both beer and wine were deified and offered to gods. Cellars and wine presses even had a god whose hieroglyph was a winepress. The ancient Egyptians made at least 17 types of beer and at least 24 varieties of wine. The most common type of beer was known as hqt. Beer was the drink of common laborers; financial accounts report that the Giza pyramid builders were allotted a daily beer ration of one and one-third gallons. Alcoholic beverages were used for pleasure, nutrition, medicine, ritual, remuneration and funerary purposes. The latter involved storing the beverages in tombs of the deceased for their use in the after-life. 

Numerous accounts of the period stressed the importance of moderation, and these norms were both secular and religious. While Egyptians did not generally appear to define drunkenness as a problem, they warned against taverns (which were often houses of prostitution) and excessive drinking. After reviewing extensive evidence regarding the widespread but generally moderate use of alcoholic beverages, the nutritional biochemist and historian William J. Darby makes a most important observation: all these accounts are warped by the fact that moderate users "were overshadowed by their more boisterous counterparts who added 'color' to history." Thus, the intemperate use of alcohol throughout history receives a disproportionate amount of attention.Those who abuse alcohol cause problems, draw attention to themselves, are highly visible and cause legislation to be enacted. The vast majority of drinkers, who neither experience nor cause difficulties, are not noteworthy. Consequently, observers and writers largely ignore moderation.

Evidence of distillation comes from alchemists working in Alexandria, Roman Egypt, in the 1st century AD. Distilled water has been known since at least c. 200 AD, when Alexander of Aphrodisias described the process.

Ancient Babylon

Beer was the major beverage among the Babylonians, and as early as 2700 BC they worshiped a wine goddess and other wine deities. Babylonians regularly used both beer and wine as offerings to their gods. Around 1750 BC, the famous Code of Hammurabi devoted attention to alcohol. However, there were no penalties for drunkenness; in fact, it was not even mentioned. The concern was fair commerce in alcohol. Although it was not a crime, the Babylonians were critical of drunkenness.

Ancient India

Alcohol distillation likely originated in India. Alcoholic beverages in the Indus Valley Civilization appeared in the Chalcolithic Era. These beverages were in use between 3000 BC and 2000 BC. Sura, a beverage brewed from rice meal, wheat, sugar cane, grapes, and other fruits, was popular among the Kshatriya warriors and the peasant population. Sura is considered to be a favorite drink of Indra.

The Hindu Ayurvedic texts describe both the beneficent uses of alcoholic beverages and the consequences of intoxication and alcoholic diseases. Ayurvedic texts concluded that alcohol was a medicine if consumed in moderation, but a poison if consumed in excess. Most of the people in India and China, have continued, throughout, to ferment a portion of their crops and nourish themselves with the alcoholic product. 

In ancient India, alcohol was also used by the orthodox population. Early Vedic literature suggests the use of alcohol by priestly classes.

The two great Hindu epics, Ramayana and Mahabharata, mention the use of alcohol. In Ramayana, alcohol consumption is depicted in a good/bad dichotomy. The bad faction members consumed meat and alcohol while the good faction members were abstinent vegetarians. However, in Mahabharata, the characters are not portrayed in such a black-white contrast.

Alcohol abstinence was promoted as a moral value in India by Mahavira, the founder of Jainism, and Adi Shankaracharya.

Distillation was known in the ancient Indian subcontinent, evident from baked clay retorts and receivers found at Taxila and Charsadda in modern Pakistan, dating back to the early centuries of the Common Era. These "Gandhara stills" were only capable of producing very weak liquor, as there was no efficient means of collecting the vapors at low heat.

Ancient Greece

While the art of wine making reached the Hellenic peninsula by about 2000 BC, the first alcoholic beverage to obtain widespread popularity in what is now Greece was mead, a fermented beverage made from honey and water. However, by 1700 BC, wine making was commonplace. During the next thousand years wine drinking assumed the same function so commonly found around the world: It was incorporated into religious rituals. It became important in hospitality, used for medicinal purposes, and became an integral part of daily meals. As a beverage, it was drunk in many ways: warm and chilled, pure and mixed with water, plain and spiced. Alcohol, specifically wine, was considered so important to the Greeks that consumption was considered a defining characteristic of the Hellenic culture between their society and the rest of the world; those who did not drink were considered barbarians.

While habitual drunkenness was rare, intoxication at banquets and festivals was not unusual. In fact, the symposium, a gathering of men for an evening of conversation, entertainment and drinking typically ended in intoxication. However, while there are no references in ancient Greek literature to mass drunkenness among the Greeks, there are references to it among foreign peoples. By 425 BC, warnings against intemperance, especially at symposia, appear to become more frequent.

Xenophon (431-351 BC) and Plato (429-347 BC) both praised the moderate use of wine as beneficial to health and happiness, but both were critical of drunkenness, which appears to have become a problem. Plato also believed that no one under the age of eighteen should be allowed to touch wine. Hippocrates (cir. 460-370 BC) identified numerous medicinal properties of wine, which had long been used for its therapeutic value. Later, both Aristotle (384-322 BC) and Zeno (cir. 336-264 BC) were very critical of drunkenness.

Among Greeks, the Macedonians viewed intemperance as a sign of masculinity and were well known for their drunkenness. Their king, Alexander the Great (356-323 BC), whose mother adhered to the Dionysian cult, developed a reputation for inebriety.

Pre-Columbian America

Several Native American civilizations developed alcoholic beverages. Many versions of these beverages are still produced today. 

Pulque, or octli is an alcoholic beverage made from the fermented juice of the maguey, and is a traditional native beverage of Mesoamerica. Though commonly believed to be a beer, the main carbohydrate is a complex form of fructose rather than starch. Pulque is depicted in Native American stone carvings from as early as AD 200. The origin of pulque is unknown, but because it has a major position in religion, many folk tales explain its origins. 

Balché is the name of a honey wine brewed by the Maya, associated with the Mayan deity Acan. The drink shares its name with the balché tree (Lonchocarpus violaceus), the bark of which is fermented in water together with honey from the indigenous stingless bee

Tepache is a mildly alcoholic beverage indigenous to Mexico that is created by fermenting pineapple, including the rind, for a short period of three days. 

Tejuino, traditional to the Mexican state of Jalisco, is a maize-based beverage that involves fermenting masa dough. 

Chicha is a Spanish word for any of variety of traditional fermented beverages from the Andes region of South America. It can be made of maize, manioc root (also called yuca or cassava) or fruits among other things. During the Inca Empire women were taught the techniques of brewing chicha in Acllahuasis (feminine schools). Chicha de jora is prepared by germinating maize, extracting the malt sugars, boiling the wort, and fermenting it in large vessels, traditionally huge earthenware vats, for several days. In some cultures, in lieu of germinating the maize to release the starches, the maize is ground, moistened in the chicha maker's mouth and formed into small balls which are then flattened and laid out to dry. Naturally occurring diastase enzymes in the maker's saliva catalyzes the breakdown of starch in the maize into maltose. Chicha de jora has been prepared and consumed in communities throughout in the Andes for millennia. The Inca used chicha for ritual purposes and consumed it in vast quantities during religious festivals. In recent years, however, the traditionally prepared chicha is becoming increasingly rare. Only in a small number of towns and villages in southern Peru and Bolivia is it still prepared. 

Cauim is a traditional alcoholic beverage of the Native American populations of Brazil since pre-Columbian times. It is still made today in remote areas throughout Panama and South America. Cauim is very similar to chicha and it is also made by fermenting manioc or maize, sometimes flavored with fruit juices. The Kuna Indians of Panama use plantains. A characteristic feature of the beverage is that the starting material is cooked, chewed, and re-cooked prior to fermentation. As in the making of chicha, enzymes from the saliva of the cauim maker breakdown the starches into fermentable sugars. 

Tiswin, or niwai is a mild, fermented, ceremonial beverage produced by various cultures living in the region encompassing the southwestern United States and northern Mexico. Among the Apache, tiswin was made from maize, while the Tohono O'odham brewed tiswin using saguaro sap. The Tarahumara variety, called tesgüino, can be made from a variety of different ingredients. Recent archaeological evidence has also revealed the production of a similar maize-based intoxicant among the ancestors of the Pueblo peoples. 

In addition, the Iroquois fermented sap from the sugar maple tree to produce a mildly alcoholic beverage.

Ancient Rome

Bacchus, the god of wine - for the Greeks, Dionysus - is the patron deity of agriculture and the theater. He was also known as the Liberator (Eleutherios), freeing one from one's normal self, by madness, ecstasy, or wine. The divine mission of Dionysus was to mingle the music of the aulos and to bring an end to care and worry. The Romans would hold dinner parties where wine was served to the guest all day along with a three course feast. Scholars have discussed Dionysus' relationship to the "cult of the souls" and his ability to preside over communication between the living and the dead.
The Roman belief that wine was a daily necessity made the drink "democratic" and ubiquitous: wine was available to slaves, peasants, women and aristocrats alike. To ensure the steady supply of wine to Roman soldiers and colonists, viticulture and wine production spread to every part of the empire. The Romans diluted their wine before drinking. Wine was also used for religious purposes, in the pouring of libations to deities. 

Though beer was drunk in Ancient Rome, it was replaced in popularity by wine. Tacitus wrote disparagingly of the beer brewed by the Germanic peoples of his day. Thracians were also known to consume beer made from rye, even since the 5th century BC, as the ancient Greek logographer Hellanicus of Lesbos says. Their name for beer was brutos, or brytos. The Romans called their brew cerevisia, from the Celtic word for it. Beer was apparently enjoyed by some Roman legionaries. For instance, among the Vindolanda tablets (from Vindolanda in Roman Britain, dated c. 97-103 AD), the cavalry decurion Masculus wrote a letter to prefect Flavius Cerialis inquiring about the exact instructions for his men for the following day. This included a polite request for beer to be sent to the garrison (which had entirely consumed its previous stock of beer).

Ancient Sub-Saharan Africa

Palm wine played an important social role in many African societies. 

Thin, gruel-like, alcoholic beverages have existed in traditional societies all across the African continent, created through the fermentation of sorghum, millet, bananas, or in modern times, maize or cassava.

Medieval period

Medieval Middle East

Schematic of a still
 
Middle-Eastern scientists used distillation extensively in their alchemical experiments, the most notable of whom were the Persian-Arab Jābir ibn Hayyān (Geber), the Arab Al-Kindi (Alkindus) and the other Persian scientist Muhammad ibn Zakariya al-Razi (Rhazes). Geber is acknowledged to be the father of the science of chemistry. He established the principle of classifying substances by their properties and invented equipment and techniques for isolating them. His technical innovations included the alembic still, whose principles still govern the production of alcoholic spirits.

Al-Kindi unambiguously described the true distillation of wine in the 9th century. As an alchemist, Razi is known for his study of sulfuric acid and for his discovery of ethanol and its refinement to use in medicine. He became chief physician of Rey and Baghdad hospitals. Razi invented what today is known as rubbing alcohol.

Medieval China and Medieval India

Distillation in China could have begun during the Eastern Han Dynasty (during the 1st & 2nd centuries), but the earliest archaeological evidence found so far indicates that the true distillation of alcohol began sometime during the Jin or Southern Song dynasties. A still has been found at an archaeological site in Qinglong, Hebei, dating to the 12th century.

In India, the true distillation of alcohol was introduced from the Middle East. It was in wide use in the Delhi Sultanate by the 14th century.

Medieval Europe

The process of distillation spread from the Middle East to Italy, where evidence of the distillation of alcohol appears from the School of Salerno in the 12th century. Fractional distillation was developed by Tadeo Alderotti in the 13th century.

In 1500, German alchemist Hieronymus Braunschweig published Liber de arte destillandi (The Book of the Art of Distillation), the first book solely dedicated to the subject of distillation, followed in 1512 by a much expanded version. In 1651, John French published The Art of Distillation the first major English compendium of practice, though it has been claimed that much of it derives from Braunschweig's work. This includes diagrams showing an industrial rather than bench scale of the operation. 

Names like "life water" have continued to be the inspiration for the names of several types of beverages, like Gaelic whisky, French eaux-de-vie and possibly vodka. Also, the Scandinavian akvavit spirit gets its name from the Latin phrase aqua vitae

At times and places of poor public sanitation (such as Medieval Europe), the consumption of alcoholic drinks was a way of avoiding water-borne diseases such as cholera. Small beer and faux wine in particular, were used for this purpose. Although alcohol kills bacteria, its low concentration in these beverages would have had only a limited effect. More important was that the boiling of water (required for the brewing of beer) and the growth of yeast (required for fermentation of beer and wine) would kill dangerous microorganisms. The alcohol content of these beverages allowed them to be stored for months or years in simple wood or clay containers without spoiling. For this reason, they were commonly kept aboard sailing vessels as an important (or even the sole) source of hydration for the crew, especially during the long voyages of the early modern period.

Modern period

Early modern period

During the early modern period (1500–1800), Protestant leaders such as Martin Luther, John Calvin, the leaders of the Anglican Church, and even the Puritans did not differ substantially from the teachings of the Catholic Church: alcohol was a gift of God and created to be used in moderation for pleasure, enjoyment and health; drunkenness was viewed as a sin

From this period through at least the beginning of the 18th century, attitudes toward drinking were characterized by a continued recognition of the positive nature of moderate consumption and an increased concern over the negative effects of drunkenness. The latter, which was generally viewed as arising out of the increased self-indulgence of the time, was seen as a threat to spiritual salvation and societal well being. Intoxication was also inconsistent with the emerging emphasis on rational mastery of self and world and on work and efficiency.

In spite of the ideal of moderation, consumption of alcohol was often high. In the 16th century, alcohol beverage consumption reached 100 liters per person per year in Valladolid, Spain, and Polish peasants consumed up to three liters of beer per day. In Coventry, England, the average amount of beer and ale consumed was about 17 pints per person per week, compared to about three pints today; nationwide, consumption was about one pint per day per capita. Swedish beer consumption may have been 40 times higher than in modern Sweden. English sailors received a ration of a gallon of beer per day, while soldiers received two-thirds of a gallon. In Denmark, the usual consumption of beer appears to have been a gallon per day for adult laborers and sailors. It is important to note that modern beer is much stronger than the beers of the past. While current beers are 3-5% alcohol, the beer drunk in the historical past was generally 1% or so. This was known as 'small beer'. 

However, the production and distribution of spirits spread slowly. Spirit drinking was still largely for medicinal purposes throughout most of the 16th century. It has been said of distilled alcohol that "the sixteenth century created it; the seventeenth century consolidated it; the eighteenth popularized it."

A beverage that clearly made its debut during the 17th century was sparkling champagne. The credit for that development goes primarily and erroneously to Dom Perignon, the wine-master in a French abbey. Although the oldest recorded sparkling wine is Blanquette de Limoux, in 1531, the English scientist and physician Christopher Merret documented the addition of sugar to a finished wine to create a second fermentation six years before Dom Perignon joined the Abbey of Hautvillers and almost 40 years before it was claimed that he invented Champagne. Around 1668, Perignon used strong bottles, invented a more efficient cork (and one that could contain the effervescence in those strong bottles), and began developing the technique of blending the contents. However, another century would pass before problems, especially bursting bottles, would be solved and champagne would become popular.

The original grain spirit, whisky (or whiskey in Hiberno-English) and its specific origins are unknown but the distillation of whisky has been performed in Ireland and Scotland for centuries. The first confirmed written record of whisky comes from 1405 in Ireland, the production of whisky from malted barley is first mentioned in Scotland in an entry from 1494, although both countries could have distilled grain alcohol before this date.

Distilled spirit was generally flavored with juniper berries. The resulting beverage was known as jenever, the Dutch word for "juniper." The French changed the name to genievre, which the English changed to "geneva" and then modified to "gin." Originally used for medicinal purposes, the use of gin as a social drink did not grow rapidly at first. However, in 1690, England passed "An Act for the Encouraging of the Distillation of Brandy and Spirits from Corn" and within four years the annual production of distilled spirits, most of which was gin, reached nearly one million gallons. "Corn" in the British English of the time meant "grain" in general, while in American English "corn" refers principally to maize

The dawn of the 18th century saw the British Parliament pass legislation designed to encourage the use of grain for distilling spirits. In 1685, consumption of gin had been slightly over one-half million gallons but by 1714 it stood at two million gallons. In 1727, official (declared and taxed) production reached five million gallons; six years later the London area alone produced eleven million gallons of gin. The English government actively promoted gin production to utilize surplus grain and to raise revenue. Encouraged by public policy, very cheap spirits flooded the market at a time when there was little stigma attached to drunkenness and when the growing urban poor in London sought relief from the newfound insecurities and harsh realities of urban life. Thus developed the so-called Gin Epidemic.

While the negative effects of that phenomenon may have been exaggerated, Parliament passed legislation in 1736 to discourage consumption by prohibiting the sale of gin in quantities of less than two gallons and raising the tax on it dramatically. However, the peak in consumption was reached seven years later, when the nation of six and one-half million people drank over 18 million gallons of gin. And most was consumed by the small minority of the population then living in London and other cities; people in the countryside largely consumed beer, ale and cider.

After its peak, gin consumption rapidly declined. From eighteen million gallons in 1743, it dropped to just over seven million gallons in 1751 and to less than two million by 1758, and generally declined to the end of the century. A number of factors appear to have converged to discourage consumption of gin. These include the production of higher quality beer of lower price, rising corn prices and taxes which eroded the price advantage of gin, a temporary ban on distilling, an increasing criticism of drunkenness, a newer standard of behavior that criticized coarseness and excess, increased tea and coffee consumption, an increase in piety and increasing industrialization with a consequent emphasis on sobriety and labor efficiency.

While drunkenness was still an accepted part of life in the 18th century, the 19th century would bring a change in attitudes as a result of increasing industrialization and the need for a reliable and punctual work force. Self-discipline was needed in place of self-expression, and task orientation had to replace relaxed conviviality. Drunkenness would come to be defined as a threat to industrial efficiency and growth.

Ethanol can produce a state of general anesthesia and historically has been used for this purpose (Dundee et al., 1969).

Problems commonly associated with industrialization and rapid urbanization were also attributed to alcohol. Thus, problems such as urban crime, poverty and high infant mortality rates were blamed on alcohol, although "it is likely that gross overcrowding and unemployment had much to do with these problems." Over time, more and more personal, social and religious/moral problems would be blamed on alcohol. And not only would it be enough to prevent drunkenness; any consumption of alcohol would come to be seen as unacceptable. Groups that began by promoting the moderate use of alcohol instead of its abuse- would ultimately form temperance movements and press for the complete and total prohibition of the production and distribution of beverage alcohol. Unfortunately, this would not eliminate social problems but would compound the situation by creating additional problems wherever it was implemented.

The Thirteen Colonies

Interior view of the Toll Gate Saloon in Black Hawk, Colorado (1897)
 
Alcoholic beverages played an important role in the Thirteen Colonies from their early days. For example, the Mayflower shipped more beer than water when it departed for the New World in 1620. While this may seem strange viewed from the modern context, note that drinking wine and beer at that time was safer than drinking water - which was usually taken from sources also used to dispose of sewage and garbage. Experience showed that it was safer to drink alcohol than the typically polluted water in Europe. Alcohol was also an effective analgesic, provided energy necessary for hard work, and generally enhanced the quality of life. 

For hundreds of years the English ancestors of the colonists had consumed beer and ale. Both in England and in the New World, people of both sexes and all ages typically drank beer with their meals. Because importing a continuing supply of beer was expensive, the early settlers brewed their own. However, it was difficult to make the beer they were accustomed to because wild yeasts caused problems in fermentation and resulted in a bitter, unappetizing brew. Although wild hops grew in New England, hop seeds were ordered from England in order to cultivate an adequate supply for traditional beer. In the meantime, the colonists improvised a beer made from red and black spruce twigs boiled in water, as well as a ginger beer

 
Beer was designated[by whom?] X, XX, or XXX according to its alcohol content. The colonists also learned to make a wide variety of wine from fruits. They additionally made wine from such products as flowers, herbs, and even oak leaves. Early on, French vine-growers were brought to the New World to teach settlers how to cultivate grapes. 

J.W. Swarts Saloon in Charleston, Arizona in 1885
 
Colonists adhered to the traditional belief that distilled spirits were aqua vitae, or water of life. However, rum was not commonly available until after 1650, when it was imported from the Caribbean. The cost of rum dropped after the colonists began importing molasses and cane sugar directly and distilled their own rum. By 1657, a rum distillery was operating in Boston. It was highly successful and within a generation the production of rum became colonial New England's largest and most prosperous industry. 

Almost every important town from Massachusetts to the Carolinas had a rum distillery to meet the local demand, which had increased dramatically. Rum was often enjoyed in mixed drinks, including flip. This was a popular winter beverage made of rum and beer sweetened with sugar and warmed by plunging a red-hot fireplace poker into the serving mug. Alcohol was viewed positively while its abuse was condemned. Increase Mather (d. 1723) expressed the common view in a sermon against drunkenness: "Drink is in itself a good creature of God, and to be received with thankfulness, but the abuse of drink is from Satan; the wine is from God, but the drunkard is from the Devil."

The United States of America

In the early 19th century, Americans had inherited a hearty drinking tradition. Many types of alcohol were consumed. One reason for this heavy drinking was attributed to an overabundance of corn on the western frontier, which encouraged the widespread production of cheap whiskey. It was at this time that alcohol became an important part of the American diet. In the 1820s, Americans drank seven gallons of alcohol per person annually.

In colonial America, water contamination was common. Two means to ensure that waterborne illness, for example typhoid and cholera, was not conveyed by water was to boil it in the process of making tea or coffee, or to use it to make alcohol. As a result, alcohol consumption was much higher in the nineteenth century than it is today -- 7.1 US gallons (27 l) of pure alcohol per person per year. Before the construction of the Erie Canal, transportation of grain from the west was cost prohibitive; farmers instead converted their grain to alcohol for shipping eastward. This dependence on alcohol as a revenue source led to the Whiskey Rebellion of 1794. Later in the nineteenth century opposition to alcohol grew in the form of the temperance movement, culminating in Prohibition in the United States from 1920 to 1933.

Sodium fluoroacetate

From Wikipedia, the free encyclopedia

Sodium fluoroacetate
Sodium-fluoroacetate-2D-skeletal.svg
Sodium-fluoroacetate-xtal-3D-SF.png
Multiple sodium fluoroacetate molecules arranged in a crystal. Fluorines are shown in green, sodium in purple, oxygen in red.
Names
IUPAC name
Sodium 2-fluoroacetate
Other names
1080; SFA; Sodium monofluoroacetate; Compound 1080
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.000.499
KEGG
PubChem CID
RTECS number AH9100000
Properties
NaFC2H2O2
Molar mass 100.0 g/mol
Appearance Fluffy, colorless-to-white powder
Odor odorless
Melting point 200 °C (392 °F; 473 K)
Boiling point Decomposes
soluble
Hazards
Main hazards Toxic, Flammable
R/S statement (outdated) R26 R27 R28
Flash point ?
Lethal dose or concentration (LD, LC):
LD50 (median dose)
1.7 mg/kg (rat, oral)
0.34 mg/kg (rabbit, oral)
0.1 mg/kg (rat, oral)
0.3 mg/kg (guinea pig, oral)
0.1 mg/kg (mouse, oral)
US health exposure limits (NIOSH):
PEL (Permissible)
TWA 0.05 mg/m3 [skin]
REL (Recommended)
TWA 0.05 mg/m3 ST 0.15 mg/m3 [skin]
IDLH (Immediate danger)
2.5 mg/m3
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Sodium fluoroacetate is the organofluorine chemical compound with the formula FCH2CO2Na. This colourless salt has a taste similar to that of sodium chloride and is used as a metabolic poison. Sodium fluoroacetate is a synthetic chemical compound, and does not occur naturally. Potassium fluoroacetate is a different compound, and does occur naturally as an anti-herbivore metabolite in various plants. Like sodium fluoroacetate, potassium fluoroacetate can also be produced synthetically. Both are derivatives of fluoroacetic acid, a carboxylic acid. The more common fluorinated acetic acid (trifluoroacetic acid) and its derivatives are far less toxic.

History and production

The effectiveness of sodium fluoroacetate as a rodenticide was reported in 1942. The name "1080" refers to the catalogue number of the poison, which became its brand name.

The salt is synthesized by treating sodium chloroacetate with potassium fluoride.

Occurrence

Dichapetalum cymosum
 
Potassium fluoroacetate, (as opposed to the commercially manufactured synthetic compound sodium fluoroacetate) occurs naturally in at least 40 plant species in Australia, New Zealand, Brazil, and Africa. It was first identified in Dichapetalum cymosum, commonly known as gifblaar (Afrikaans) or poison leaf, by Marais in 1944. As early as 1904, colonists in Sierra Leone used extracts of Chailletia toxicaria, which also contains fluoroacetic acid or its salts, to poison rats. Several native Australian plant genera contain the toxin, including Gastrolobium, Gompholobium, Oxylobium, Nemcia, and Acacia. New Zealand's native Puha contains 1080 in very low concentrations.

Potassium fluoroacetate occurrence in Gastrolobium species

Gastrolobium is a genus of flowering plants in the family Fabaceae. There are over 100 species in this genus, and all but two are native to the south west region of Western Australia, where they are known as "poison peas". Gastrolobium growing in south western Australia are unique in their ability to concentrate fluoroacetate from low fluorine soils. Brush-tailed possums, bush rats, and western grey kangaroos native to this region are capable of safely eating plants containing fluoroacetate, but livestock and introduced species from elsewhere in Australia are highly susceptible to the poison, as are species introduced from outside Australia, such as the red fox. The fact that many Gastrolobium species also have high secondary toxicity to non-native carnivores is thought to have limited the ability of cats to establish populations in locations where the plants form a major part of the understorey vegetation.

The presence of Gastrolobium species in the fields of farmers in Western Australia has often forced these farmers to 'scalp' their land — that is, remove the top soil and any poison pea seed which it may contain, and replace it with a new poison pea-free top soil sourced from elsewhere in which to sow crops. Similarly, following bushfires in north-western Queensland cattlemen have to move livestock before the poisonous Gastrolobium grandiflorum emerges from the ashes.

Toxicology

Sodium fluoroacetate is toxic to all obligate aerobic organisms, and highly toxic to mammals and insects. The oral dose of sodium fluoroacetate sufficient to be lethal in humans is 2–10 mg/kg.

The toxicity varies with species. The New Zealand Food Safety Authority established lethal doses for a number of species. Dogs, cats, and pigs appear to be most susceptible to poisoning.

The enzyme fluoroacetate dehalogenase has been discovered in a soil bacterium, which can detoxify fluoroacetate in the surrounding medium.

Mechanism of action

Fluoroacetate is similar to acetate, which has a pivotal role in cellular metabolism. Fluoroacetate disrupts the citric acid cycle (also known as the Krebs cycle) by combining with coenzyme A to form fluoroacetyl CoA, which reacts with citrate synthase to produce fluorocitrate which binds very tightly to aconitase, thereby halting the citric acid cycle. This inhibition results in an accumulation of citrate in the blood. Citrate and fluorocitrate are allosteric inhibitors of phosphofructokinase-1 (PFK-1), a key enzyme in glycolysis. When PFK-1 is inhibited, cells are no longer able to metabolize carbohydrates, depriving them of energy.

Symptoms

In humans, the symptoms of poisoning normally appear between 30 minutes and three hours after exposure. Initial symptoms typically include nausea, vomiting, and abdominal pain; sweating, confusion, and agitation follow. In significant poisoning, cardiac abnormalities including tachycardia or bradycardia, hypotension, and ECG changes develop. Neurological effects include muscle twitching and seizures; consciousness becomes progressively impaired after a few hours leading to coma. Death is normally due to ventricular arrhythmias, progressive hypotension unresponsive to treatment, and secondary lung infections.

Symptoms in domestic animals vary: dogs tend to show nervous system signs such as convulsions, vocalization, and uncontrollable running, whilst large herbivores such as cattle and sheep more predominantly show cardiac signs.

Sub-lethal doses of sodium fluoroacetate may cause damage to tissues with high energy needs — in particular, the brain, gonads, heart, lungs, and fetus. Sub-lethal doses are typically completely metabolised and excreted within four days.

Treatment

Effective antidotes are unknown. Research in monkeys has shown that the use of glyceryl monoacetate can prevent problems if given after ingestion of sodium fluoroacetate, and this therapy has been tested in domestic animals with some positive results. In theory, glyceryl monoacetate supplies acetate ions to allow continuation of cellular respiration which the sodium fluoroacetate had disrupted.

Experiments of Dr. Goncharov and co-workers resulted in development of a successful therapeutic complex, containing a phenothiazine compound, a dioic acid compound, and a pharmaceutically acceptable carrier. In another aspect the pharmaceutical composition can include a phenothiazine compound, a nitroester compound, ethanol, and a pharmaceutically acceptable carrier.

In clinical cases, use of muscle relaxants, anti-convulsants, mechanical ventilation, and other supportive measures may all be required. Few animals or people have been treated successfully after significant sodium fluoroacetate ingestions.

In one study, sheep gut bacteria were genetically engineered to contain the fluoroacetate dehalogenase enzyme that inactivates sodium fluoroacetate. The bacteria were administered to sheep, who then showed reduced signs of toxicity after sodium fluoroacetate ingestion.

Pesticide use

Common brushtail possum, an invasive pest in New Zealand whose population is controlled with sodium fluoroacetate
 
Sodium fluoroacetate is used as a pesticide, especially for mammalian pest species. Farmers and graziers use the poison to protect pastures and crops from various herbivorous mammals. In New Zealand and Australia it is also used to control invasive non-native mammals that prey on or compete with native wildlife and vegetation.

Australia

In Australia, sodium fluoroacetate was first used in rabbit control programmes in the early 1950s, where it is regarded as having "a long history of proven effectiveness and safety". It is seen as a critical component of the integrated pest-control programmes for rabbits, foxes, wild dogs, and feral pigs. Since 1994, broad-scale fox control using 1080 meat baits in Western Australia has significantly improved the population numbers of several native species and led, for the first time, to three species of mammals being taken off the state's endangered species list. In Australia, minor direct mortality of native animal populations from 1080 baits is regarded as acceptable, compared to the predatory and competitive effects of those introduced species being managed using 1080.

Western Shield is a project to boost populations of endangered mammals in south-west Australia conducted by the DEC. The project entails distributing fluoroacetate-baited meat from the air to kill predators. Wild dogs and foxes will readily eat the baited meat. Cats pose a greater difficulty as they are generally not interested in scavenging. However, an Australian RSPCA-commissioned study criticized 1080, calling it an inhumane killer. Some Western Australian herbivores (notably, the local subspecies of the tammar wallaby, Macropus eugenii derbianus, but not the subspecies M. e. eugenii of southern Australia and M. e. decres on Kangaroo Island) have, by natural selection, developed partial immunity to the effects of fluoroacetate, so that its use as a poison may reduce collateral damage to some native herbivores specific to that area. 

In 2011, over 3,750 toxic baits containing 3 ml of 1080 were laid across 520 properties over 48,000 hectares between the Tasmanian settlements of Southport and Hobart as part of an ongoing attempt at the world's biggest invasive animal eradication operation – the eradication of red foxes from the island state. The baits were spread at the rate of one per 10 hectares and were buried, to mitigate the risk to non-target wildlife species like Tasmanian devils. Native animals are also targeted with 1080. During May 2005 up to 200,000 Bennett's wallabies on King Island were intentionally killed in one of the largest coordinated 1080 poisonings seen in Tasmania.

In 2016 PAPP (para-amino propiophenone) became available for use, which the RSPCA has endorsed as a more humane alternative to 1080 due in part to its ability to kill faster, as well as having an antidote, which 1080 does not, though as of July 2018, 1080 was still being used in attempts to reduce feral cat populations.

New Zealand

Sign warning of poisonous sodium fluoroacetate baits on the West Coast of New Zealand

Worldwide, New Zealand is the largest user of sodium fluoroacetate. This high usage is attributable to the fact that, apart from two species of bat, New Zealand has no native land mammals, and some of those that have been introduced have had devastating effects on vegetation and native species. 1080 is used to control possums, rats, stoats, deer, and rabbits. The largest users, despite some vehement opposition, are OSPRI New Zealand and the Department of Conservation.

United States

Sodium fluoroacetate is used in the United States to kill coyotes. Prior to 1972 when the EPA cancelled all uses, sodium fluoroacetate was used much more widely as a cheap predacide and rodenticide; in 1985, the restricted-use "toxic collar" approval was finalized.

Other countries

1080 is used as a rodenticide in Mexico, Japan, Korea, and Israel.

Environmental impacts

Water

Because 1080 is highly water-soluble, it will be dispersed and diluted in the environment by rain, stream water and ground water. Sodium fluoroacetate at the concentrations found in the environment after standard baiting operations will break down in natural water containing living organisms, such as aquatic plants or micro-organisms. Water-monitoring surveys, conducted during the 1990s, have confirmed that significant contamination of waterways following aerial application of 1080 bait is possible, but unlikely. Research by NIWA showed that 1080 deliberately placed in small streams for testing was undetectable after 8 hours, as it washed downstream.

In New Zealand, surface water is routinely monitored after aerial application of 1080, and water samples are collected immediately after application, when there is the highest possibility of detecting contamination. Of 2442 water samples tested in New Zealand between 1990 and 2010, following aerial 1080 operations: 96.5% had no detectable 1080 at all and, of all the samples, only six were equal to, or above the Ministry of Health level for drinking water, and none of these came from drinking water supplies. Of 592 samples taken from human or stock drinking supplies, only four contained detectable 1080 residues at 0.1ppb (1 sample) and 0.2 ppb (3 samples) – all well below the Ministry of Health level of 2 ppb. 

In an experiment funded by the Animal Health Board and conducted by NIWA simulating the effects of rainfall on 1080 on a steep soil-covered hillside a few meters from a stream, it was found that 99.9% of the water containing 1080 leached straight into the soil and did not flow over the ground to the stream as had been expected. The experiment also measured contamination of soil water, which was described as the water carried through the soil underground at short horizontal distances (0.5-3m), downhill towards the stream. The experiment did not measure contamination of deeper soil and ground water immediately beneath the site of application.

Soil

The fate of 1080 in the soil has been established by research defining the degradation of naturally occurring fluoroacetate (Oliver, 1977). Sodium fluoroacetate is water-soluble, and residues from uneaten baits leach into the soil where they are degraded to non-toxic metabolites by soil microorganisms, including bacteria (Pseudomonas) and the common soil fungus (Fusarium solani) (David and Gardiner, 1966; Bong, Cole and Walker, 1979; Walker and Bong, 1981).

Birds

Although it is now infrequent, individual aerial 1080 operations can still sometimes affect local bird populations if not carried out with sufficient care. In New Zealand, individuals from 19 species of native birds and 13 species of introduced birds have been found dead after aerial 1080 drops. Most of these recorded bird deaths were associated with only four operations in the 1970s that used poor-quality carrot baits with many small fragments. On the other hand, many native New Zealand bird populations have been successfully protected by reducing predator numbers through aerial 1080 operations. Kokako, blue duck, New Zealand pigeon, kiwi, kaka, New Zealand falcon, tomtit, South Island robin, North Island robin, New Zealand parakeets (kakariki), and yellowhead have all responded well to pest control programmes using aerial 1080 operations, with increased chick and adult survival, and increases in population size. In contrast, seven of 38 tagged kea, the endemic alpine parrot, were killed during an aerial possum control operation in Okarito Forest conducted by DOC and AHB in August 2011. Because of their omnivorous feeding habits and inquisitive behaviour, kea are known to be particularly susceptible to 1080 poison baits, as well as other environmental poisons like the zinc and lead used in the flashings of backcountry huts and farm buildings. Recent research found that proximity to human-occupied sites where kea scrounge human food is inversely related to survival; the odds of survival increased by a factor of 6.9 for remote kea compared to those that lived near scrounging sites. High survival in remote areas is explained by innate neophobia and a short field-life of prefeed baits, which together preclude acceptance of poison baits as familiar food.

Reptiles and amphibians

Reptiles and amphibians are susceptible to 1080, although much less sensitive than mammals. Amphibian and reptile species that have been tested in Australia are generally more tolerant to 1080 poison than are most other animals. McIlroy (1992) calculated that even if lizards fed entirely on insects or other animals poisoned with 1080, they could never ingest enough poison to receive a lethal dose. Laboratory trials in New Zealand simulating worst-case scenarios indicate that both Leiopelma archeyi (Archey's frog) and L. hochstetteri (Hochstetter's frog) can absorb 1080 from contaminated water, substrate, or prey. The chance of this occurring in the wild is ameliorated by a variety of factors, including frog ecology. Captive maintenance and contamination problems rendered parts of this study inconclusive. Further population monitoring is recommended to provide more conclusive evidence than provided by this single study. In New Zealand, the secondary poisoning of feral cats and stoats following 1080 operations is likely to have a positive effect on the recovery of native skink and gecko populations. Killing rabbits and possums, which compete for food with skinks and geckos, may also have benefits.

Fish

Fish generally have very low sensitivity to 1080. Toxicity tests have been conducted in the US on bluegill sunfish, rainbow trout, and the freshwater invertebrate Daphnia magna. Tests at different 1080 concentrations on sunfish (for four days) and Daphnia (two days) showed that 1080 is "practically non-toxic" (a US EPA classification) to both these species. Rainbow trout were also tested over four days at four concentrations ranging from 39 to 170 mg 1080 per litre. From these results an LC50 (the concentration of 1080 per litre of water which theoretically kills 50% of the test fish) can be calculated. The LC50 for rainbow trout was calculated to be 54 mg 1080/litre – far in excess of any known concentration of 1080 found in water samples following 1080 aerial operations. Thus 1080 is unlikely to cause mortality in freshwater fish.

Invertebrates

Insects are susceptible to 1080 poisoning. Some field trials in New Zealand have shown that insect numbers can be temporarily reduced within 20 cm of toxic baits, but numbers return to normal levels within six days of the bait being removed. Other trials have found no evidence that insect communities are negatively affected. Another New Zealand study showed that weta, native ants, and freshwater crayfish excrete 1080 within one to two weeks. There is also evidence that 1080 aerial operations in New Zealand can benefit invertebrate species. Both possums and rats are a serious threat to endemic invertebrates in New Zealand, where around 90 per cent of spiders and insects are endemic and have evolved without predatory mammals. In a study on the diet of brushtail possums, 47.5 per cent of possum faeces examined between January 1979 and June 1983 contained invertebrates, mostly insects. One possum can eat up to 60 endangered native land snails (Powelliphanta spp.) in one night.

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