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Saturday, March 21, 2015

Nanorobotics


From Wikipedia, the free encyclopedia

Nanorobotics is the emerging technology field creating machines or robots whose components are at or close to the scale of a nanometer (10−9 meters).[1][2][3] More specifically, nanorobotics refers to the nanotechnology engineering discipline of designing and building nanorobots, with devices ranging in size from 0.1–10 micrometers and constructed of nanoscale or molecular components.[4][5] The names nanobots, nanoids, nanites, nanomachines, or nanomites have also been used to describe these devices currently under research and development.[6][7]

Nanomachines are largely in the research-and-development phase,[8] but some primitive molecular machines and nanomotors have been tested. An example is a sensor having a switch approximately 1.5 nanometers across, capable of counting specific molecules in a chemical sample. The first useful applications of nanomachines might be in medical technology,[9] which could be used to identify and destroy cancer cells.[10][11] Another potential application is the detection of toxic chemicals, and the measurement of their concentrations, in the environment. Rice University has demonstrated a single-molecule car developed by a chemical process and including buckyballs for wheels. It is actuated by controlling the environmental temperature and by positioning a scanning tunneling microscope tip.

Another definition is a robot that allows precision interactions with nanoscale objects, or can manipulate with nanoscale resolution. Such devices are more related to microscopy or scanning probe microscopy, instead of the description of nanorobots as molecular machine. Following the microscopy definition even a large apparatus such as an atomic force microscope can be considered a nanorobotic instrument when configured to perform nanomanipulation. For this perspective, macroscale robots or microrobots that can move with nanoscale precision can also be considered nanorobots.

Nanorobotics theory

According to Richard Feynman, it was his former graduate student and collaborator Albert Hibbs who originally suggested to him (circa 1959) the idea of a medical use for Feynman's theoretical micromachines (see nanotechnology). Hibbs suggested that certain repair machines might one day be reduced in size to the point that it would, in theory, be possible to (as Feynman put it) "swallow the doctor". The idea was incorporated into Feynman's 1959 essay There's Plenty of Room at the Bottom.[12]

Since nanorobots would be microscopic in size, it would probably be necessary for very large numbers of them to work together to perform microscopic and macroscopic tasks. These nanorobot swarms, both those incapable of replication (as in utility fog) and those capable of unconstrained replication in the natural environment (as in grey goo and its less common variants[clarification needed]), are found in many science fiction stories, such as the Borg nanoprobes in Star Trek and The Outer Limits episode The New Breed.

Some proponents of nanorobotics, in reaction to the grey goo scenarios that they earlier helped to propagate, hold the view that nanorobots capable of replication outside of a restricted factory environment do not form a necessary part of a purported productive nanotechnology, and that the process of self-replication, if it were ever to be developed, could be made inherently safe. They further assert that their current plans for developing and using molecular manufacturing do not in fact include free-foraging replicators.[13][14]

The most detailed theoretical discussion of nanorobotics, including specific design issues such as sensing, power communication, navigation, manipulation, locomotion, and onboard computation, has been presented in the medical context of nanomedicine by Robert Freitas. Some of these discussions remain at the level of unbuildable generality and do not approach the level of detailed engineering.

Approaches

Biochip

The joint use of nanoelectronics, photolithography, and new biomaterials provides a possible approach to manufacturing nanorobots for common medical applications, such as for surgical instrumentation, diagnosis and drug delivery.[15][16][17] This method for manufacturing on nanotechnology scale is currently in use in the electronics industry.[18] So, practical nanorobots should be integrated as nanoelectronics devices, which will allow tele-operation and advanced capabilities for medical instrumentation.[19][20]

Nubots

Nubot is an abbreviation for "nucleic acid robot." Nubots are organic molecular machines at the nanoscale.[21] DNA structure can provide means to assemble 2D and 3D nanomechanical devices. DNA based machines can be activated using small molecules, proteins and other molecules of DNA.[22][23][24] Biological circuit gates based on DNA materials have been engineered as molecular machines to allow in-vitro drug delivery for targeted health problems.[25] Such material based systems would work most closely to smart biomaterial drug system delivery,[26] while not allowing precise in vivo teleoperation of such engineered prototypes.

Surface-bound systems

A number of reports have demonstrated the attachment of synthetic molecular motors to surfaces.[27][28] These primitive nanomachines have been shown to undergo machine-like motions when confined to the surface of a macroscopic material. The surface anchored motors could potentially be used to move and position nanoscale materials on a surface in the manner of a conveyor belt.

Positional nanoassembly

Nanofactory Collaboration,[29] founded by Robert Freitas and Ralph Merkle in 2000 and involving 23 researchers from 10 organizations and 4 countries, focuses on developing a practical research agenda[30] specifically aimed at developing positionally-controlled diamond mechanosynthesis and a diamondoid nanofactory that would have the capability of building diamondoid medical nanorobots.

Bacteria-based

This approach proposes the use of biological microorganisms, like the bacterium Escherichia coli.[31] Thus the model uses a flagellum for propulsion purposes. Electromagnetic fields normally control the motion of this kind of biological integrated device.[32] Chemists at the University of Nebraska have created a humidity gauge by fusing a bacteria to a silicone computer chip.[33]

Virus-based

Retroviruses can be retrained to attach to cells and replace DNA. They go through a process called reverse transcription to deliver genetic packaging in a vector.[34] Usually, these devices are Pol – Gag genes of the virus for the Capsid and Delivery system. This process is called retroviral Gene Therapy, having the ability to re-engineer cellular DNA by usage of viral vectors.[35] This approach has appeared in the form of Retroviral, Adenoviral, and Lentiviral gene delivery systems.[36] These Gene Therapy vectors have been used in cats to send genes into the genetic modified animal "GMO" causing it display the trait. [37]

Open technology

A document with a proposal on nanobiotech development using open technology approaches has been addressed to the United Nations General Assembly.[38] According to the document sent to the UN, in the same way that Open Source has in recent years accelerated the development of computer systems, a similar approach should benefit the society at large and accelerate nanorobotics development. The use of nanobiotechnology should be established as a human heritage for the coming generations, and developed as an open technology based on ethical practices for peaceful purposes. Open technology is stated as a fundamental key for such an aim.

Nanorobot race

In the same ways that technology development had the space race and nuclear arms race, a race for nanorobots is occurring.[39][40][41][42][43] There is plenty of ground allowing nanorobots to be included among the emerging technologies.[44] Some of the reasons are that large corporations, such as General Electric, Hewlett-Packard, Synopsys, Northrop Grumman and Siemens have been recently working in the development and research of nanorobots;[45][46][47][48][49] surgeons are getting involved and starting to propose ways to apply nanorobots for common medical procedures;[50] universities and research institutes were granted funds by government agencies exceeding $2 billion towards research developing nanodevices for medicine;[51][52] bankers are also strategically investing with the intent to acquire beforehand rights and royalties on future nanorobots commercialization.[53]
Some aspects of nanorobot litigation and related issues linked to monopoly have already arisen.[54][55][56] A large number of patents has been granted recently on nanorobots, done mostly for patent agents, companies specialized solely on building patent portfolio, and lawyers. After a long series of patents and eventually litigations, see for example the Invention of Radio or about the War of Currents, emerging fields of technology tend to become a monopoly, which normally is dominated by large corporations.[57]

Potential applications

Nanomedicine

Potential applications for nanorobotics in medicine include early diagnosis and targeted drug-delivery for cancer,[58][59][60] biomedical instrumentation,[61] surgery,[62][63] pharmacokinetics,[10] monitoring of diabetes,[64][65][66] and health care.
In such plans, future medical nanotechnology is expected to employ nanorobots injected into the patient to perform work at a cellular level. Such nanorobots intended for use in medicine should be non-replicating, as replication would needlessly increase device complexity, reduce reliability, and interfere with the medical mission.

Nanotechnology provides a wide range of new technologies for developing customized solutions that optimize the delivery of pharmaceutical products. Today, harmful side effects of treatments such as chemotherapy are commonly a result of drug delivery methods that don't pinpoint their intended target cells accurately.[67] Researchers at Harvard and MIT, however, have been able to attach special RNA strands, measuring nearly 10 nm in diameter, to nano-particles, filling them with a chemotherapy drug. These RNA strands are attracted to cancer cells. When the nanoparticle encounters a cancer cell, it adheres to it, and releases the drug into the cancer cell.[68] This directed method of drug delivery has great potential for treating cancer patients while avoiding negative effects (commonly associated with improper drug delivery).[67][69] The first demonstration of nanomotors operating in living organism was carried out in 2014 at UCSD, San Diego.[70]

Another useful application of nanorobots is assisting in the repair of tissue cells alongside white blood cells.[71] The recruitment of inflammatory cells or white blood cells (which include neutrophils, lymphocytes, monocytes and mast cells) to the affected area is the first response of tissues to injury.[72] Because of their small size nanorobots could attach themselves to the surface of recruited white cells, to squeeze their way out through the walls of blood vessels and arrive at the injury site, where they can assist in the tissue repair process. Certain substances could possibly be utilized to accelerate the recovery.

The science behind this mechanism is quite complex. Passage of cells across the blood endothelium, a process known as transmigration, is a mechanism involving engagement of cell surface receptors to adhesion molecules, active force exertion and dilation of the vessel walls and physical deformation of the migrating cells. By attaching themselves to migrating inflammatory cells, the robots can in effect “hitch a ride” across the blood vessels, bypassing the need for a complex transmigration mechanism of their own.[71]

The US FDA currently regulates nanotechnology on the basis of size.[73] The FDA also regulates that which acts by chemical means as a drug, and that which acts by physical means as a device.[74] Single molecules can also be used as Turing machines, like their larger paper tape counterparts, capable of universal computation and exerting physical (or chemical) forces as a result of that computation. Safety systems are being developed so that if a drug payload were to be accidentally released, the payload would either be inert or another drug would be then released to counteract the first. Toxicological testing becomes convolved with software validation in such circumstances.With new advances in nanotechnology these small devices are being created with the ability to self-regulate and be ‘smarter’ than previous generations. As nanotechnology becomes more complex, how will regulatory agencies distinguish a drug from a device?[74] Drug molecules must undergo slower and more expensive testing (for example, preclinical toxicological testing) than devices, and the regulatory pathways for devices are simpler than for drugs. Perhaps smartness, if smart enough, will someday be used to justify a device classification for a single molecule nanomachine. Devices are generally approved more quickly than drugs, so device classification could be beneficial to patients and manufacturers.

Biorobotics


From Wikipedia, the free encyclopedia

Biorobotics is a term that loosely covers the fields of cybernetics, bionics and even genetic engineering as a collective study.

Biorobotics is often used to refer to a real subfield of robotics: studying how to make robots that emulate or simulate living biological organisms mechanically or even chemically. The term is also used in a reverse definition: making biological organisms as manipulatable and functional as robots, or making biological organisms as components of robots.

In the latter sense, biorobotics can be referred to as a theoretical discipline of comprehensive genetic engineering in which organisms are created and designed by artificial means. The creation of life from non-living matter for example, would be biorobotics. The field is in its infancy and is sometimes known as synthetic biology or bionanotechnology.

In fiction, biorobotics makes many appearances, like the biots of the novel Rendezvous with Rama or the replicants of the film Blade Runner.

Biorobotics in Fiction

Biorobotics has made many appearances in works of fiction, often in the form of synthetic biological organisms.

Augmentations feature as a major plot device in Deus Ex and its prequel Deus Ex: Human Revolution, with nano and mechanical variations, respectively. The advent of such augmentation that is conducive to previously inhuman feats results in widespread civil unrest, fundamentally challenging the self-perception and identity of humanity.

The robots featured in Rossum's Universal Robots, the play that originally coined the term robot, are presented as synthetic biological entities closer to biological organisms than the mechanical objects that the term robot came to refer to. The replicants in the film Blade Runner are biological in nature: they are organisms of living tissue and cells created artificially. In the novel The Windup Girl by Paolo Bacigalupi, "windups" or "New People" are genetically engineered organisms.

The word biot, a portmanteau of "biological robot", was originally coined by Arthur C. Clarke in his 1972 novel Rendezvous with Rama. Biots are depicted as artificial biological organisms created to perform specific tasks on the space vessel Rama. This affects their physical attributes and cognitive abilities.

Humanoid Cylons in the 2004 television series Battlestar Galactica are another example of biological robots in fictions. Almost undistinguishable from humans, they are artificial creations created by mechanical cylons.

The authors of the Star Wars book series The New Jedi Order reprised the term biot. The Yuuzhan Vong uses the term to designate their biotechnology.

The term bioroid, or biological android, as also been used to designate artificial biological organisms, like in the manga Appleseed. In 1985 the animated Robotech television series popularized the term when it reused the term from the 1984 Japanese series The Super Dimension Cavalry Southern Cross.

The term reploid, or replicate-android, is used in the Capcom video game series Mega ManX. Much like Blade Runner's replicants these beings are more human in thinking and emotional awareness then previous generations, despite some being made into animal shapes to purposely distinguish them from humans. Another further future form of these robots, seen in Mega Man Zero, have them being so close to humans that they can actually eat, sleep, and reproduce. The only thing setting them apart is their semi-inorganic skeletal systems. In another farther flung future version and evolution of these bio-machines in the series Mega Man ZX humans and robots have merged seemingly so closely they are no longer a separate race but in-fact two parts to a whole new race. The final future of the game series is Mega Man Legends where humans and robots are one being to the point they can actually get together and reproduce offspring without effort.

In Warhammer 40k Imperium (Warhammer 40,000) uses servitors, vat-grown humans with cybernetic parts replacing most parts of the body.They lack emotions or intelligence and are only capable of simple tasks. A more advanced imperial robots are used by the imperium, instead of using humans they are mostly machine and has biological brain and some other biological parts. Unlike servitors they are capable of having programmed instincts when killing but still they lack any true intelligence.

Practical experimentation

A biological brain, grown from cultured neurons which were originally separated, has been developed as the neurological entity subsequently embodied within a robot body by Kevin Warwick and his team at University of Reading. The brain receives input from sensors on the robot body and the resultant output from the brain provides the robot's only motor signals. The biological brain is the only brain of the robot.[1]

Cyborg


From Wikipedia, the free encyclopedia

A cyborg (short for "cybernetic organism") is a theoretical or fictional being with both organic and biomechatronic parts. The term was coined in 1960 by Manfred Clynes and Nathan S. Kline.[1] D. S. Halacy's Cyborg: Evolution of the Superman in 1965 featured an introduction which spoke of a "new frontier" that was "not merely space, but more profoundly the relationship between 'inner space' to 'outer space' – a bridge...between mind and matter."[2]
The term cyborg is not the same thing as bionic and often applied to an organism that has restored function or enhanced abilities due to the integration of some artificial component or technology that relies on some sort of feedback.[3][4] While cyborgs are commonly thought of as mammals, they might also conceivably be any kind of organism and the term "Cybernetic organism" has been applied to networks, such as road systems, corporations and governments, which have been classed as such. The term can also apply to micro-organisms which are modified to perform at higher levels than their unmodified counterparts. It is hypothesized that cyborg technology will form a part of the future human evolution.

In popular culture, some cyborgs may be represented as visibly mechanical (e.g. the Cybermen in the Doctor Who franchise or The Borg from Star Trek or Darth Vader from Star Wars); or as almost indistinguishable from humans (e.g. the Terminators from the Terminator films, the "Human" Cylons from the re-imagining of Battlestar Galactica etc.) The 1970s television series The Six Million Dollar Man featured one of the most famous fictional cyborgs, referred to as a bionic man; the series was based upon a novel by Martin Caidin titled Cyborg. Cyborgs in fiction often play up a human contempt for over-dependence on technology, particularly when used for war, and when used in ways that seem to threaten free will. Cyborgs are also often portrayed with physical or mental abilities far exceeding a human counterpart (military forms may have inbuilt weapons, among other things).

Overview

According to some definitions of the term, the physical attachments humanity has with even the most basic technologies have already made them cyborgs.[5] In a typical example, a human with an artificial cardiac pacemaker or implantable cardioverter-defibrillator would be considered a cyborg, since these devices measure voltage potentials in the body, perform signal processing, and can deliver electrical stimuli, using this synthetic feedback mechanism to keep that person alive. Implants, especially cochlear implants, that combine mechanical modification with any kind of feedback response are also cyborg enhancements. Some theorists[who?] cite such modifications as contact lenses, hearing aids, or intraocular lenses as examples of fitting humans with technology to enhance their biological capabilities; however, these modifications are as cybernetic as a pen or a wooden leg. As cyborgs currently are on the rise some theorists argue there is a need to develop new definitions of aging and for instance a bio-techno-social definition of aging has been suggested.[6]

The term is also used to address human-technology mixtures in the abstract. This includes not only commonly used pieces of technology such as phones, computers, the Internet, etc. but also artifacts that may not popularly be considered technology; for example, pen and paper, and speech and language. When augmented with these technologies and connected in communication with people in other times and places, a person becomes capable of much more than they were before. This is like a computer, which gains power by using Internet protocols to connect with other computers. Cybernetic technologies include highways, pipes, electrical wiring, buildings, electrical plants, libraries, and other infrastructure that we hardly notice, but which are critical parts of the cybernetics that we work within.

Bruce Sterling in his universe of Shaper/Mechanist suggested an idea of alternative cyborg called Lobster, which is made not by using internal implants, but by using an external shell (e.g. a Powered Exoskeleton).[7] Unlike human cyborgs that appear human externally while being synthetic internally, a Lobster looks inhuman externally but contains a human internally. The computer game Deus Ex: Invisible War prominently featured cyborgs called Omar, where "Omar" is a Russian translation of the word "Lobster" (since the Omar are of Russian origin in the game).

Origins

The concept of a man-machine mixture was widespread in science fiction before World War II. As early as 1843, Edgar Allan Poe described a man with extensive prostheses in the short story "The Man That Was Used Up". In 1908, Jean de la Hire introduced Nyctalope (perhaps the first true superhero was also the first literary cyborg) in the novel L'Homme Qui Peut Vivre Dans L'eau (The Man Who Can Live in the Water). Edmond Hamilton presented space explorers with a mixture of organic and machine parts in his novel The Comet Doom in 1928. He later featured the talking, living brain of an old scientist, Simon Wright, floating around in a transparent case, in all the adventures of his famous hero, Captain Future. He uses the term explicitly in the 1962 short story, "After a Judgment Day," to describe the "mechanical analogs" called "Charlies," explaining that "[c]yborgs, they had been called from the first one in the 1960s...cybernetic organisms." In the short story "No Woman Born" in 1944, C. L. Moore wrote of Deirdre, a dancer, whose body was burned completely and whose brain was placed in a faceless but beautiful and supple mechanical body.

The term was coined by Manfred E. Clynes and Nathan S. Kline in 1960 to refer to their conception of an enhanced human being who could survive in extraterrestrial environments:


Their concept was the outcome of thinking about the need for an intimate relationship between human and machine as the new frontier of space exploration was beginning to open up. A designer of physiological instrumentation and electronic data-processing systems, Clynes was the chief research scientist in the Dynamic Simulation Laboratory at Rockland State Hospital in New York.

The term first appears in print five months earlier when The New York Times reported on the Psychophysiological Aspects of Space Flight Symposium where Clynes and Kline first presented their paper.


A book titled Cyborg: Digital Destiny and Human Possibility in the Age of the Wearable computer was published by Doubleday in 2001.[10] Some of the ideas in the book were incorporated into the 35mm motion picture film Cyberman.

Cyborg tissues in engineering

Cyborgs tissues structured with carbon nanotubes and plant or fungal cells have been used in artificial tissue engineering to produce new materials for mechanical and electrical uses. The work was presented by Di Giacomo and Maresca at MRS 2013 Spring conference on Apr, 3rd, talk number SS4.04.[11] The cyborg obtained is inexpensive, light and has unique mechanical properties. It can also be shaped in desired forms. Cells combined with MWCNTs co-precipitated as a specific aggregate of cells and nanotubes that formed a viscous material.
Likewise, dried cells still acted as a stable matrix for the MWCNT network. When observed by optical microscopy the material resembled an artificial “tissue” composed of highly packed cells. The effect of cell drying is manifested by their “ghost cell” appearance. A rather specific physical interaction between MWCNTs and cells was observed by electron microscopy suggesting that the cell wall (the most outer part of fungal and plant cells) may play a major active role in establishing a CNTs network and its stabilization. This novel material can be used in a wide range of electronic applications from heating to sensing and has the potential to open important new avenues to be exploited in electromagnetic shielding for radio frequency electronics and aerospace technology. In particular using Candida albicans cells cyborg tissue materials with temperature sensing properties have been reported. [12]

Individual cyborgs


Neil Harbisson, cyborg activist and president of the Cyborg Foundation.[13]

Jens Naumann, a man with acquired blindness, being interviewed about his vision BCI on CBS's The Early Show

Generally, the term "cyborg" is used to refer to a human with bionic, or robotic, implants.

In current prosthetic applications, the C-Leg system developed by Otto Bock HealthCare is used to replace a human leg that has been amputated because of injury or illness. The use of sensors in the artificial C-Leg aids in walking significantly by attempting to replicate the user's natural gait, as it would be prior to amputation.[14] Prostheses like the C-Leg and the more advanced iLimb are considered by some to be the first real steps towards the next generation of real-world cyborg applications. Additionally cochlear implants and magnetic implants which provide people with a sense that they would not otherwise have had can additionally be thought of as creating cyborgs.

In vision science, direct brain implants have been used to treat non-congenital (acquired) blindness. One of the first scientists to come up with a working brain interface to restore sight was private researcher William Dobelle. Dobelle's first prototype was implanted into "Jerry", a man blinded in adulthood, in 1978. A single-array BCI containing 68 electrodes was implanted onto Jerry's visual cortex and succeeded in producing phosphenes, the sensation of seeing light. The system included cameras mounted on glasses to send signals to the implant. Initially, the implant allowed Jerry to see shades of grey in a limited field of vision at a low frame-rate. This also required him to be hooked up to a two-ton mainframe, but shrinking electronics and faster computers made his artificial eye more portable and now enable him to perform simple tasks unassisted.[15]

In 1997, Philip Kennedy, a scientist and physician designed the world's first human cyborg named Johnny Ray. Ray was a Vietnam veteran in Georgia who suffered a stroke. Unfortunately, Ray's body, as doctor's called it, was "locked in". Ray wanted his old life back so he agreed to Kennedy's experiment. Kennedy embedded a Neurotrophic Electrode near the part of Ray's brain so that Ray would be able to have some movement back in his body. The surgery went successfully, but in 2002, Johnny Ray died.[16]

In 2002, Canadian Jens Naumann, also blinded in adulthood, became the first in a series of 16 paying patients to receive Dobelle's second generation implant, marking one of the earliest commercial uses of BCIs. The second generation device used a more sophisticated implant enabling better mapping of phosphenes into coherent vision. Phosphenes are spread out across the visual field in what researchers call the starry-night effect. Immediately after his implant, Jens was able to use his imperfectly restored vision to drive slowly around the parking area of the research institute.[17]

In 2002, under the heading Project Cyborg, a British scientist, Kevin Warwick, had an array of 100 electrodes fired into his nervous system in order to link his nervous system into the Internet. With this in place he successfully carried out a series of experiments including extending his nervous system over the Internet to control a robotic hand, a loudspeaker and amplifier. This is a form of extended sensory input and the first direct electronic communication between the nervous systems of two humans.[18][19]

In 2004, under the heading Bridging the Island of the Colourblind Project, a British and completely color-blind artist, Neil Harbisson, started wearing an eyeborg on his head in order to perceive colors through hearing.[20] His prosthetic device was included within his 2004 passport photograph which has been claimed to confirm his cyborg status.[21] In 2012 at TEDGlobal,[22] Harbisson explained that he did not feel like a cyborg when he started to use the eyeborg, he started to feel like a cyborg when he noticed that the software and his brain had united and given him an extra sense.[22]

Animal cyborgs

The US-based company Backyard Brains released what they refer to as "The world's first commercially available cyborg" called the RoboRoach. The project started as a University of Michigan biomedical engineering student senior design project in 2010[23] and was launched as an available beta product on 25 February 2011.[24] The RoboRoach was officially released into production via a TED talk at the TED Global conference,[25] and via the crowdsourcing website Kickstarter in 2013,[26] the kit allows students to use microstimulation to momentarily control the movements of a walking cockroach (left and right) using a bluetooth-enabled smartphone as the controller. Other groups have developed cyborg insects, including researchers at North Carolina State University[27] and UC Berkeley,[28] but the RoboRoach was the first kit available to the general public and was funded by the National Institute of Mental Health as a device to serve as a teaching aid to promote an interest in neuroscience.[25] Several animal welfare organizations including the RSPCA [29] and PETA [30] have expressed concerns about the ethics and welfare of animals in this project.

Social cyborgs

More broadly, the full term "cybernetic organism" is used to describe larger networks of communication and control. For example, cities, networks of roads, networks of software, corporations, markets, governments, and the collection of these things together. A corporation can be considered as an artificial intelligence that makes use of replaceable human components to function. People at all ranks can be considered replaceable agents of their functionally intelligent government institutions, whether such a view is desirable or not. The example above is reminiscent of the "organic paradigm" popular in the late 19th century due to the era's breakthroughs in understanding of cellular biology.

Jaap van Till tries to quantify this effect with his Synthecracy Network Law: V ~ N !, where V is value and N is number of connected people. This factorial growth is what he claims leads to a herd or hive like thinking between large, electronically connected groups.

Cyborg proliferation in society

In finance

Due to advances in computer technology, investors are able to employ super computers to engage in financial activities such as trading, banking, brokering, and money management. Because of the increased reliance on artificial intelligence and advanced computerization, modern finance is becoming “cyborg finance” because the key players are part human and part machine.[31] One key characteristic of cyborg finance is the use of incredibly powerful and fast computers to analyze and execute trading opportunities based on complex mathematical models.
The software employing these algorithms is often proprietary and non-transparent, thus it is sometimes referred to as “black-box trading.”

In medicine

In medicine, there are two important and different types of cyborgs: the restorative and the enhanced. Restorative technologies "restore lost function, organs, and limbs".[32] The key aspect of restorative cyborgization is the repair of broken or missing processes to revert to a healthy or average level of function. There is no enhancement to the original faculties and processes that were lost.

On the contrary, the enhanced cyborg "follows a principle, and it is the principle of optimal performance: maximising output (the information or modifications obtained) and minimising input (the energy expended in the process)".[33] Thus, the enhanced cyborg intends to exceed normal processes or even gain new functions that were not originally present.

Although prostheses in general supplement lost or damaged body parts with the integration of a mechanical artifice, bionic implants in medicine allow model organs or body parts to mimic the original function more closely. Michael Chorost wrote a memoir of his experience with cochlear implants, or bionic ear, titled "Rebuilt: How Becoming Part Computer Made Me More Human."[34] Jesse Sullivan became one of the first people to operate a fully robotic limb through a nerve-muscle graft, enabling him a complex range of motions beyond that of previous prosthetics.[35] By 2004, a fully functioning artificial heart was developed.[36] The continued technological development of bionic and nanotechnologies begins to raise the question of enhancement, and of the future possibilities for cyborgs which surpass the original functionality of the biological model. The ethics and desirability of "enhancement prosthetics" have been debated; their proponents include the transhumanist movement, with its belief that new technologies can assist the human race in developing beyond its present, normative limitations such as aging and disease, as well as other, more general incapacities, such as limitations on speed, strength, endurance, and intelligence. Opponents of the concept describe what they believe to be biases which propel the development and acceptance of such technologies; namely, a bias towards functionality and efficiency that may compel assent to a view of human people which de-emphasizes as defining characteristics actual manifestations of humanity and personhood, in favor of definition in terms of upgrades, versions, and utility.[37]

A brain-computer interface, or BCI, provides a direct path of communication from the brain to an external device, effectively creating a cyborg. Research of Invasive BCIs, which utilize electrodes implanted directly into the grey matter of the brain, has focused on restoring damaged eyesight in the blind and providing functionality to paralyzed people, most notably those with severe cases, such as Locked-In syndrome. This technology could enable people who are missing a limb or are in a wheelchair the power to control the devices that aide them through neural signals sent from the brain implants directly to computers or the devices. It is possible that this technology will also eventually be used with healthy people.[38]

Deep brain stimulation is a neurological surgical procedure used for therapeutic purposes. This process has aided in treating patients diagnosed with Parkinson's disease, Alzheimer's disease, Tourette syndrome, epilepsy, chronic headaches, and mental disorders. After the patient is unconscious, through anesthesia, brain pacemakers or electrodes, are implanted into the region of the brain where the cause of the disease is present. The region of the brain is then stimulated by bursts of electrical current to disrupt the oncoming surge of seizures. Like all invasive procedures, deep brain stimulation may put the patient at a higher risk. However, there have been more improvements in recent years with deep brain stimulation than any available drug treatment.[39]

Retinal implants are another form of cyborgization in medicine. The theory behind retinal stimulation to restore vision to people suffering from retinitis pigmentosa and vision loss due to aging (conditions in which people have an abnormally low amount of ganglion cells) is that the retinal implant and electrical stimulation would act as a substitute for the missing ganglion cells (cells which connect the eye to the brain.)

While work to perfect this technology is still being done, there have already been major advances in the use of electronic stimulation of the retina to allow the eye to sense patterns of light. A specialized camera is worn by the subject, such as on the frames of their glasses, which converts the image into a pattern of electrical stimulation. A chip located in the user's eye would then electrically stimulate the retina with this pattern by exciting certain nerve endings which transmit the image to the optic centers of the brain and the image would then appear to the user. If technological advances proceed as planned this technology may be used by thousands of blind people and restore vision to most of them.

A similar process has been created to aide people who have lost their vocal cords. This experimental device would do away with previously used robotic sounding voice simulators. The transmission of sound would start with a surgery to redirect the nerve that controls the voice and sound production to a muscle in the neck, where a nearby sensor would be able to pick up its electrical signals. The signals would then move to a processor which would control the timing and pitch of a voice simulator. That simulator would then vibrate producing a multitonal sound which could be shaped into words by the mouth.[40]

An August 26, 2012 article from Harvard University's homepage, by Peter Reuell of the Harvard Gazette, proceeds to discuss three-dimensional cyborg tissue research, published in the journal Nature Materials, with possible medical implications done by Charles M. Lieber, the Mark Hyman Jr. Professor of Chemistry, and Daniel Kohane, a Harvard Medical School Anesthesiology Professor at Boston Children's Hospital.[41]

In the military

Military organizations' research has recently focused on the utilisation of cyborg animals for the purposes of a supposed tactical advantage. DARPA has announced its interest in developing "cyborg insects" to transmit data from sensors implanted into the insect during the pupal stage. The insect's motion would be controlled from a Micro-Electro-Mechanical System (MEMS) and could conceivably survey an environment or detect explosives and gas.[42] Similarly, DARPA is developing a neural implant to remotely control the movement of sharks. The shark's unique senses would then be exploited to provide data feedback in relation to enemy ship movement or underwater explosives.[43]

In 2006, researchers at Cornell University invented[44] a new surgical procedure to implant artificial structures into insects during their metamorphic development.[45][46] The first insect cyborgs, moths with integrated electronics in their thorax, were demonstrated by the same researchers.[47][48] The initial success of the techniques has resulted in increased research and the creation of a program called Hybrid-Insect-MEMS, HI-MEMS. Its goal, according to DARPA's Microsystems Technology Office, is to develop "tightly coupled machine-insect interfaces by placing micro-mechanical systems inside the insects during the early stages of metamorphosis".[49]

The use of neural implants has recently been attempted, with success, on roaches. Surgically applied electrodes were put on the insect, which were remotely controlled by a human. The results, although sometimes different, basically showed that the roach could be controlled by the impulses it received through the electrodes. DARPA is now funding this research because of its obvious beneficial applications to the military and other areas[50]

In 2009 at the Institute of Electrical and Electronics Engineers (IEEE) Micro-electronic mechanical systems (MEMS) conference in Italy, researchers demonstrated the first "wireless" flying-beetle cyborg.[51] Engineers at the University of California at Berkeley have pioneered the design of a "remote controlled beetle", funded by the DARPA HI-MEMS Program. Filmed evidence of this can be viewed here.[52] This was followed later that year by the demonstration of wireless control of a "lift-assisted" moth-cyborg.[53]

Eventually researchers plan to develop HI-MEMS for dragonflies, bees, rats and pigeons.[54][55] For the HI-MEMS cybernetic bug to be considered a success, it must fly 100 metres (330 ft) from a starting point, guided via computer into a controlled landing within 5 metres (16 ft) of a specific end point. Once landed, the cybernetic bug must remain in place.[54]

In art

The concept of the cyborg is often associated with science fiction. However, many artists have tried to create public awareness of cybernetic organisms; these can range from paintings to installations. Some artists who create such works are Neil Harbisson, Moon Ribas, Patricia Piccinini, Steve Mann, Orlan, H. R. Giger, Lee Bul, Wafaa Bilal, Tim Hawkinson and Stelarc.

Stelarc is a performance artist who has visually probed and acoustically amplified his body. He uses medical instruments, prosthetics, robotics, virtual reality systems, the Internet and biotechnology to explore alternate, intimate and involuntary interfaces with the body. He has made three films of the inside of his body and has performed with a third hand and a virtual arm. Between 1976–1988 he completed 25 body suspension performances with hooks into the skin. For 'Third Ear' he surgically constructed an extra ear within his arm that was internet enabled, making it a publicly accessible acoustical organ for people in other places.[56] He is presently performing as his avatar from his second life site.[57]

Tim Hawkinson promotes the idea that bodies and machines are coming together as one, where human features are combined with technology to create the Cyborg. Hawkinson's piece Emoter presented how society is now dependent on technology.[58]

Wafaa Bilal is an Iraqi-American performance artist who had a small 10 megapixel digital camera surgically implanted into the back of his head, part of a project entitled 3rd I.[59] For one year, beginning 15 December 2010, an image is captured once per minute 24 hours a day and streamed live to www.3rdi.me and the Mathaf: Arab Museum of Modern Art. The site also displays Bilal's location via GPS. Bilal says that the reason why he put the camera in the back of the head was to make an "allegorical statement about the things we don't see and leave behind."[60] As a professor at NYU, this project has raised privacy issues, and so Bilal has been asked to ensure that his camera does not take photographs in NYU buildings.[60]

Machines are becoming more ubiquitous in the artistic process itself, with computerized drawing pads replacing pen and paper, and drum machines becoming nearly as popular as human drummers. This is perhaps most notable in generative art and music. Composers such as Brian Eno have developed and utilized software which can build entire musical scores from a few basic mathematical parameters.[61]

Scott Draves is a generative artist whose work is explicitly described as a "cyborg mind". His Electric Sheep project generates abstract art by combining the work of many computers and people over the internet.[62]

Artists as cyborgs

Artists have explored the term cyborg from a perspective involving imagination. Some work to make an abstract idea of technological and human-bodily union apparent to reality in an art form utilizing varying mediums, from sculptures and drawings to digital renderings. Artists that seek to make cyborg-based fantasies a reality often call themselves cyborg artists, or may consider their artwork "cyborg". How an artist or their work may be considered cyborg will vary depending upon the interpreter's flexibility with the term. Scholars that rely upon a strict, technical description of cyborg, often going by Norbert Wiener's cybernetic theory and Manfred E. Clynes and Nathan S. Kline's first use of the term, would likely argue that most cyborg artists do not qualify to be considered cyborgs.[63] Scholars considering a more flexible description of cyborgs may argue it incorporates more than cybernetics.[64]
Others may speak of defining subcategories, or specialized cyborg types, that qualify different levels of cyborg at which technology influences an individual. This may range from technological instruments being external, temporary, and removable to being fully integrated and permanent.[65] Nonetheless, cyborg artists are artists. Being so, it can be expected for them to incorporate the cyborg idea rather than a strict, technical representation of the term,[66] seeing how their work will sometimes revolve around other purposes outside of cyborgism.[63]

In body modification

As medical technology becomes more advanced, some techniques and innovations are adopted by the body modification community. While not yet cyborgs in the strict definition of Manfred Clynes and Nathan Kline, technological developments like implantable silicon silk electronics,[67] augmented reality[68] and QR codes[69] are bridging the disconnect between technology and the body. Hypothetical technologies such as digital tattoo interfaces[70][71] would blend body modification aesthetics with interactivity and functionality, bringing a transhumanist way of life into present day reality.

In addition, it is quite plausible for anxiety expression to manifest. Individuals may experience pre-implantation feelings of fear and nervousness. To this end, individuals may also embody feelings of uneasiness, particularly in a socialized setting, due to their post-operative, technologically augmented bodies, and mutual unfamiliarity with the mechanical insertion. Anxieties may be linked to notions of otherness or a cyborged identity.[72]

In popular culture

Cyborgs have become a well-known part of science fiction literature and other media. Although many of these characters may be technically androids, they are often referred to as cyborgs. Well-known examples from film and television include RoboCop, Terminators, Evangelion, The Six Million Dollar Man, Replicants from Blade Runner, Daleks and Cybermen from Doctor Who, the Borg from Star Trek, Darth Vader and General Grievous from Star Wars, Inspector Gadget, and Cylons from the 2004 Battlestar Galactica series. From manga and anime are characters such as 8 Man (the inspiration for RoboCop), Kamen Rider, Ghost in the Shell's Motoko Kusanagi, as well as characters from western comic books like Tony Stark (after his Extremis and Bleeding Edge armor) and Victor "Cyborg" Stone. The Deus Ex videogame series deals extensively with the near-future rise of cyborgs and their corporate ownership, as does the Syndicate series.

Cyborgization in critical deaf studies

Joseph Michael Valente, describes "cyborgization" as an attempt to codify "normalization" through cochlear implantation in young deaf children. Drawing from Paddy Ladd's work on Deaf epistemology and Donna Haraway's Cyborg ontology, Valente "use[s] the concept of the cyborg as a way of agitating constructions of cyborg perfection (for the deaf child that would be to become fully hearing)". He claims that cochlear implant manufacturers advertise and sell cochlear implants as a mechanical device as well as an uncomplicated medical "miracle cure". Valente criticizes cochlear implant researchers whose studies largely to date do not include cochlear implant recipients, despite cochlear implants having been approved by the United States Food and Drug Administration (FDA) since 1984.[73] Pamela J. Kincheloe discusses the representation of the cochlear implant in media and popular culture as a case study for present and future responses to human alteration and enhancement.[74]

Cyborg Foundation

In 2010, the Cyborg Foundation became the world's first international organization dedicated to help humans become cyborgs.[75] The foundation was created by cyborg Neil Harbisson and Moon Ribas as a response to the growing amount of letters and emails received from people around the world interested in becoming a cyborg.[76]
The foundation's main aims are to extend human senses and abilities by creating and applying cybernetic extensions to the body,[77] to promote the use of cybernetics in cultural events and to defend cyborg rights.[78] In 2010, the foundation, based in Mataró (Barcelona), was the overall winner of the Cre@tic Awards, organized by Tecnocampus Mataró.[79]

In 2012, Spanish film director Rafel Duran Torrent, created a short film about the Cyborg Foundation. In 2013, the film won the Grand Jury Prize at the Sundance Film Festival's Focus Forward Filmmakers Competition and was awarded with $100,000 USD.[80]

Profane (religion)

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