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Wednesday, August 6, 2014

Higgs boson

Higgs boson

Condensed from Wikipedia, the free encyclopedia
   
Higgs boson
Candidate Higgs Events in ATLAS and CMS.png
Candidate Higgs boson events from collisions between protons in the LHC. The top event in the CMS experiment shows a decay into two photons (dashed yellow lines and green towers). The lower event in the ATLAS experiment shows a decay into 4 muons (red tracks).[Note 1]
CompositionElementary particle
StatisticsBosonic
StatusA Higgs boson of mass ≈125 GeV has been tentatively confirmed by CERN on 14 March 2013,[1][2][3] although unclear as yet which model the particle best supports or whether multiple Higgs bosons exist.[2]
(See: Current status)
SymbolH0
TheorisedR. Brout, F. Englert, P. Higgs, G. S. Guralnik, C. R. Hagen, and T. W. B. Kibble (1964)
DiscoveredPreviously unknown boson confirmed to exist on 4 July 2012, by the ATLAS and CMS teams at the Large Hadron Collider; tentatively confirmed as a Higgs boson of some kind on 14 March 2013 (see above).
Mass125.03+0.26
−0.27
 
(stat) +0.13
−0.15
 
(sys) GeV/c2
,[4]
125.36 ± 0.37 (stat) ± 0.18 (sys) GeV/c2[5]
Mean lifetime1.56×10−22 s[Note 2] (predicted in the Standard Model)
Decays into(observed) W and Z bosons, two photons. (Others still being studied)
Electric charge0
Color charge0
Spin0 (tentatively confirmed at 125 GeV)[1]
Parity+1 (tentatively confirmed at 125 GeV)[1]
The Higgs boson or Higgs particle is an elementary particle initially theorised in 1964,[2][6] whose discovery was announced at CERN on 4 July 2012.[7] The discovery has been called "monumental"[8][9] because it appears to confirm the existence of the Higgs field,[10][11] which is pivotal to the Standard Model and other theories within particle physics. It would explain why some fundamental particles have mass when the symmetries controlling their interactions should require them to be massless, and why the weak force has a much shorter range than the electromagnetic force. The discovery of a Higgs boson should allow physicists to finally validate the last untested area of the Standard Model's approach to fundamental particles and forces, guide other theories and discoveries in particle physics, and potentially lead to developments in "new" physics.[12]

This unanswered question in fundamental physics is of such importance[10][11] that it led to a search of more than 40 years for the Higgs boson and finally the construction of one of the world's most expensive and complex experimental facilities to date, the Large Hadron Collider,[13] able to create Higgs bosons and other particles for observation and study. On 4 July 2012, it was announced that a previously unknown particle with a mass between 125 and 127 GeV/c2 (134.2 and 136.3 amu) had been detected; physicists suspected at the time that it was the Higgs boson.[14][9][15] By March 2013, the particle had been proven to behave, interact and decay in many of the ways predicted by the Standard Model, and was also tentatively confirmed to have positive parity and zero spin,[1] two fundamental attributes of a Higgs boson. This appears to be the first elementary scalar particle discovered in nature.[16] More data are needed to determine whether the particle discovered exactly matches the predictions of the Standard Model, or whether, as predicted by some theories, multiple Higgs bosons exist.[3]

The Higgs boson is named after Peter Higgs, one of six physicists who, in 1964, proposed the mechanism that suggested the existence of such a particle. Although Higgs's name has come to be associated with this theory, several researchers between about 1960 and 1972 each independently developed different parts of it. In mainstream media the Higgs boson has often been called the "God particle", from a 1993 book on the topic; the nickname is strongly disliked by many physicists, including Higgs, who regard it as inappropriate sensationalism.[17][18] In 2013 two of the original researchers, Peter Higgs and François Englert, were awarded the Nobel Prize in Physics for their work and prediction.[19] Englert's co-researcher Robert Brout had died in 2011 and the Nobel is not given posthumously except in unusual circumstances.

In the Standard Model, the Higgs particle is a boson with no spin, electric charge, or color charge. It is also very unstable, decaying into other particles almost immediately. It is a quantum excitation of one of the four components of the Higgs field. The latter constitutes a scalar field, with two neutral and two electrically charged components, and forms a complex doublet of the weak isospin SU(2) symmetry. The field has a "Mexican hat" shaped potential with nonzero strength everywhere (including otherwise empty space), which in its vacuum state breaks the weak isospin symmetry of the electroweak interaction. When this happens, three components of the Higgs field are "absorbed" by the SU(2) and U(1) gauge bosons (the "Higgs mechanism") to become the longitudinal components of the now-massive W and Z bosons of the weak force. The remaining electrically neutral component separately couples to other particles known as fermions (via Yukawa couplings), causing these to acquire mass as well. Some versions of the theory predict more than one kind of Higgs fields and bosons. Alternative "Higgsless" models would have been considered if the Higgs boson were not discovered.

Overview

In particle physics, elementary particles and forces give rise to the world around us. Nowadays, physicists explain the behaviour of these particles and how they interact using the Standard Model—a widely accepted and "remarkably" accurate[21] framework based on gauge invariance and symmetries, believed to explain almost everything in the world we see, other than gravity.[22]
But by around 1960 all attempts to create a gauge invariant theory for two of the four fundamental forces had consistently failed at one crucial point: although gauge invariance seemed extremely important, it seemed to make any theory of electromagnetism and the weak force go haywire, by demanding that either many particles with mass were massless or that non-existent forces and massless particles had to exist. Scientists had no idea how to get past this point.

Work done on superconductivity and "broken" symmetries around 1960 led physicist Philip Anderson to suggest in 1962 a new kind of solution that might hold the key. In 1964 a theory was created by 3 different groups of researchers, that showed the problems could be resolved if an unusual kind of field existed throughout the universe. It would cause existing particles to acquire mass instead of new massless particles being formed. By 1972 it had been developed into a comprehensive theory and proved capable of giving "sensible" results. Although there was not yet any proof of such a field, calculations consistently gave answers and predictions that were confirmed by experiments, including very accurate predictions of several other particles,[Note 7] so scientists began to believe this might be true and to search for proof whether or not a Higgs field exists in nature.

If this field did exist, this would be a monumental discovery for science and human knowledge, and is expected to open doorways to new knowledge in many fields. If not, then other more complicated theories would need to be explored. The easiest proof whether or not the field existed was by searching for a new kind of particle it would have to give off, known as "Higgs bosons" or the "Higgs particle". These would be extremely difficult to find, so it was only many years later that experimental technology became sophisticated enough to answer the question.

While several symmetries in nature are spontaneously broken through a form of the Higgs mechanism, in the context of the Standard Model the term "Higgs mechanism" almost always means symmetry breaking of the electroweak field. It is considered proven, but the exact cause has been exceedingly difficult to prove. After 50 years, the Higgs boson's existence – apparently proven in 2013 – would finally confirm that the Standard Model is essentially correct and allow further development, while its non-existence would mean that other theories are needed instead.
Various analogies have also been invented to describe the Higgs field and boson, including analogies with well-known symmetry breaking effects such as the rainbow and prism, electric fields, ripples, and resistance of macro objects moving through media, like people moving through crowds or some objects moving through syrup or molasses. However, analogies based on simple resistance to motion are inaccurate as the Higgs field does not work by resisting motion.

Significance

Scientific impact

Evidence of the Higgs field and its properties would be extremely significant scientifically, for many reasons. The Higgs boson's importance is largely that it is able to be examined using existing knowledge and experimental technology, as a way to confirm and study the entire Higgs field theory.[10][11] Conversely, proof that the Higgs field and boson do not exist would also be significant. In discussion form, the relevance includes:
Validating the Standard Model, or choosing between extensions and alternativesDoes the Higgs field exist, which fundamentally validates the Standard Model? If it does, then which more advanced extensions are suggested or excluded based upon measurements of its properties? What else can we learn about this fundamental field, now that we have the experimental means to study its behavior and interactions? Alternatively, if the Higgs field doesn't exist, which alternatives and modifications to the Standard Model are likely to be preferred? Will the data suggest an extension, or a completely different approach (such as supersymmetry or string theory)? Related to this, a belief generally exists among physicists that there is likely to be "new" physics beyond the Standard Model—the Standard Model will at some point be extended or superseded. The Higgs field and related issues present a promising "doorway" to understand better the places where the Standard Model might become inadequate or fail, and could provide considerable evidence guiding researchers into future enhancements or successors.
Finding how symmetry breaking happens within the electroweak interactionBelow an extremely high temperature, electroweak symmetry breaking causes the electroweak interaction to manifest in part as the short-ranged weak force, which is carried by massive gauge bosons. Without this, the universe we see around us could not exist, because atoms and other structures could not form, and reactions in stars such as our Sun would not occur. But it is not clear how this actually happens in nature. Is the Standard Model correct in its approach, and can it be made more exact with actual experimental measurements? If not the Higgs field, then what is breaking symmetry in its place?
Finding how certain particles acquire massElectroweak symmetry breaking (due to a Higgs field or otherwise) is believed proven responsible for the masses of fundamental particles such as elementary fermions (including electrons and quarks) and the massive W and Z gauge bosons. Finding how this happens is pivotal to particle physics. It is worth noting that the Higgs field does not 'create' mass out of nothing (which would violate the law of conservation of energy). Nor is the Higgs field responsible for the mass of all particles. For example, about 99% of the mass of baryons (composite particles such as the proton and neutron) is due instead to the kinetic energy of quarks and to the energies of (massless) gluons of the strong interaction inside the baryons.[23] In Higgs-based theories, the property of 'mass' is a manifestation of potential energy transferred to particles when they interact ("couple") with the Higgs field, which had contained that mass in the form of energy.[24]
Evidence whether or not scalar fields exist in nature, and "new" physicsProof of a scalar field such as the Higgs field would be hard to overestimate: "[The] verification of real scalar fields would be nearly as important as its role in generating mass". [9] Rolf-Dieter Heuer, director general of CERN, stated in a 2011 talk on the Higgs field:[25]
"All the matter particles are spin-1/2 fermions. All the force carriers are spin-1 bosons. Higgs particles are spin-0 bosons (scalars). The Higgs is neither matter nor force. The Higgs is just different. This would be the first fundamental scalar ever discovered. The Higgs field is thought to fill the entire universe. Could it give some handle of dark energy (scalar field)? Many modern theories predict other scalar particles like the Higgs. Why, after all, should the Higgs be the only one of its kind? [The] LHC can search for and study new scalars with precision."
Insight into cosmic inflationThere has been considerable scientific research on possible links between the Higgs field and the inflaton – a hypothetical field suggested as the explanation for the expansion of space during the first fraction of a second of the universe (known as the "inflationary epoch"). Some theories suggest that a fundamental scalar field might be responsible for this phenomenon; the Higgs field is such a field and therefore has led to papers analysing whether it could also be the inflaton responsible for this exponential expansion of the universe during the Big Bang. Such theories are highly tentative and face significant problems related to unitarity, but may be viable if combined with additional features such as large non-minimal coupling, a Brans–Dicke scalar, or other "new" physics, and have received treatments suggesting that Higgs inflation models are still of interest theoretically.
Insight into the nature of the universe, and its possible fates
Higgs-Mass-MetaStability.svg
Diagram showing the Higgs boson and top quark masses, which could indicate whether our universe is stable, or a long-lived 'bubble'. As of 2012, the 2σ ellipse based on Tevatron and LHC data still allows for both possibilities.[26]
For decades, scientific models of our universe have included the possibility that it exists as a long-lived, but not completely stable, sector of space, which could potentially at some time be destroyed upon 'toppling' into a more stable vacuum state.[27][28][29][30][31] If the masses of the Higgs boson and top quark are known more exactly, and the Standard Model provides a correct description of particle physics up to extreme energies of the Planck scale, then it is possible to calculate whether the universe's present vacuum state is stable or merely long-lived.[32][33][34] (This was sometimes misreported as the Higgs boson "ending" the universe[38]). A 125 – 127 GeV Higgs mass seems to be extremely close to the boundary for stability (estimated in 2012 as 123.8 – 135.0 GeV[26]) but a definitive answer requires much more precise measurements of the top quark's pole mass.[26]
If measurements of the Higgs boson suggest that our universe lies within a false vacuum of this kind, then it would imply – more than likely in many billions of years[39][Note 8] – that the universe's forces, particles, and structures could cease to exist as we know them (and be replaced by different ones), if a true vacuum happened to nucleate.[39][Note 9] It also suggests that the Higgs self-coupling λ and its βλ function could be very close to zero at the Planck scale, with "intriguing" implications, including theories of gravity and Higgs-based inflation.[26]:218[41][42] A future electron–positron collider would be able to provide the precise measurements of the top quark needed for such calculations.[26]
Insight into the 'energy of the vacuum'More speculatively, the Higgs field has also been proposed as the energy of the vacuum, which at the extreme energies of the first moments of the Big Bang caused the universe to be a kind of featureless symmetry of undifferentiated extremely high energy. In this kind of speculation, the single unified field of a Grand Unified Theory is identified as (or modeled upon) the Higgs field, and it is through successive symmetry breakings of the Higgs field or some similar field at phase transitions that the present universe's known forces and fields arise.[43]
Link to the 'cosmological constant' problemThe relationship (if any) between the Higgs field and the presently observed vacuum energy density of the universe has also come under scientific study. As observed, the present vacuum energy density is extremely close to zero, but the energy density expected from the Higgs field, supersymmetry, and other current theories are typically many orders of magnitude larger. It is unclear how these should be reconciled. This cosmological constant problem remains a further major unanswered problem in physics.
Further information: Zero-point energy and Vacuum state

"Real world" impact[edit]

As yet, there are no known immediate technological benefits of finding the Higgs particle. However, observers in both media and science point out that when fundamental discoveries are made about our world, their practical uses can take decades to emerge, but are often world-changing when they do.[44][45][46] A common pattern for fundamental discoveries is for practical applications to follow later, once the discovery has been explored further, at which point they become the basis for social change and new technologies.

For example, in the first half of the 20th century it was not expected that quantum mechanics would make possible transistors and microchips, mobile phones and computers, lasers and M.R.I. scanners.[47] Radio waves were described by their co-discoverer in 1888 as "an interesting laboratory experiment" with "no useful purpose" whatsoever,[48] and are now used in innumerable ways (radar, weather prediction, medicine, television, wireless computing and emergency response), positrons are used in hospital tomography scans, and special and general relativity, which explain black holes also enable satellite-based GPS and satellite navigation ("satnav").[47] Electric power generation and transmission, motors, and lighting all stemmed from previous theoretical work on electricity and magnetism; air conditioning and refrigeration resulted from thermodynamics. It is impossible to predict how seemingly esoteric knowledge may affect society in the future.[44][46]

Other observers highlight technological spin-offs from this and related particle physics activities, which have already brought major developments to society. For example, the World Wide Web as used today was created by physicists working in global collaborations on particle experiments at CERN to share their results, and the results of massive amounts of data produced by the Large Hadron Collider have already led to significant advances in distributed and cloud computing, now well established within mainstream services.[45]

Theoretical properties

Theoretical need for the Higgs

"Symmetry breaking illustrated": – At high energy levels (left) the ball settles in the center, and the result is symmetrical. At lower energy levels (right), the overall "rules" remain symmetrical, but the "Mexican hat" potential comes into effect: "local" symmetry inevitably becomes broken since eventually the ball must at random roll one way or another.

Gauge invariance is an important property of modern particle theories such as the Standard Model, partly due to its success in other areas of fundamental physics such as electromagnetism and the strong interaction (quantum chromodynamics). However, there were great difficulties in developing gauge theories for the weak nuclear force or a possible unified electroweak interaction. Fermions with a mass term would violate gauge symmetry and therefore cannot be gauge invariant. (This can be seen by examining the Dirac Lagrangian for a fermion in terms of left and right handed components; we find none of the spin-half particles could ever flip helicity as required for mass, so they must be massless.[Note 12]) W and Z bosons are observed to have mass, but a boson mass term contains terms, which clearly depend on the choice of gauge and therefore these masses too cannot be gauge invariant. Therefore it seems that none of the standard model fermions or bosons could "begin" with mass as an inbuilt property except by abandoning gauge invariance. If gauge invariance were to be retained, then these particles had to be acquiring their mass by some other mechanism or interaction. Additionally, whatever was giving these particles their mass, had to not "break" gauge invariance as the basis for other parts of the theories where it worked well, and had to not require or predict unexpected massless particles and long-range forces (seemingly an inevitable consequence of Goldstone's theorem) which did not actually seem to exist in nature.

A solution to all of these overlapping problems came from the discovery of a previously unnoticed borderline case hidden in the mathematics of Goldstone's theorem,[Note 10] that under certain conditions it might theoretically be possible for a symmetry to be broken without disrupting gauge invariance and without any new massless particles or forces, and having "sensible" (renormalisable) results mathematically: this became known as the Higgs mechanism.

The Standard Model hypothesizes a field which is responsible for this effect, called the Higgs field (symbol: \phi), which has the unusual property of a non-zero amplitude in its ground state; i.e., a non-zero vacuum expectation value. It can have this effect because of its unusual "Mexican hat" shaped potential whose lowest "point" is not at its "centre". Below a certain extremely high energy level the existence of this non-zero vacuum expectation spontaneously breaks electroweak gauge symmetry which in turn gives rise to the Higgs mechanism and triggers the acquisition of mass by those particles interacting with the field. This effect occurs because scalar field components of the Higgs field are "absorbed" by the massive bosons as degrees of freedom, and couple to the fermions via Yukawa coupling, thereby producing the expected mass terms. In effect when symmetry breaks under these conditions, the Goldstone bosons that arise interact with the Higgs field (and with other particles capable of interacting with the Higgs field) instead of becoming new massless particles, the intractable problems of both underlying theories "neutralise" each other, and the residual outcome is that elementary particles acquire a consistent mass based on how strongly they interact with the Higgs field. It is the simplest known process capable of giving mass to the gauge bosons while remaining compatible with gauge theories.[86] Its quantum would be a scalar boson, known as the Higgs boson.[87]
Summary of interactions between certain particles described by the Standard Model.

Properties of the Standard Model Higgs

In the Standard Model, the Higgs field consists of four components, two neutral ones and two charged component fields. Both of the charged components and one of the neutral fields are Goldstone bosons, which act as the longitudinal third-polarization components of the massive W+, W, and Z bosons. The quantum of the remaining neutral component corresponds to (and is theoretically realised as) the massive Higgs boson.[88] Since the Higgs field is a scalar field (meaning it does not transform under Lorentz transformations), the Higgs boson has no spin. The Higgs boson is also its own antiparticle and is CP-even, and has zero electric and colour charge.[89]

The Minimal Standard Model does not predict the mass of the Higgs boson.[90] If that mass is between 115 and 180 GeV/c2, then the Standard Model can be valid at energy scales all the way up to the Planck scale (1019 GeV).[91] Many theorists expect new physics beyond the Standard Model to emerge at the TeV-scale, based on unsatisfactory properties of the Standard Model.[92] The highest possible mass scale allowed for the Higgs boson (or some other electroweak symmetry breaking mechanism) is 1.4 TeV; beyond this point, the Standard Model becomes inconsistent without such a mechanism, because unitarity is violated in certain scattering processes.[93]

It is also possible, although experimentally difficult, to estimate the mass of the Higgs boson indirectly. In the Standard Model, the Higgs boson has a number of indirect effects; most notably, Higgs loops result in tiny corrections to masses of W and Z bosons. Precision measurements of electroweak parameters, such as the Fermi constant and masses of W/Z bosons, can be used to calculate constraints on the mass of the Higgs. As of July 2011, the precision electroweak measurements tell us that the mass of the Higgs boson is likely to be less than about 161 GeV/c2 at 95% confidence level (this upper limit would increase to 185 GeV/c2 if the lower bound of 114.4 GeV/c2 from the LEP-2 direct search is allowed for[85]). These indirect constraints rely on the assumption that the Standard Model is correct. It may still be possible to discover a Higgs boson above these masses if it is accompanied by other particles beyond those predicted by the Standard Model.[94]

Production

Feynman diagrams for Higgs production
Gluon fusion
Gluon fusion
Higgs Strahlung
Higgs Strahlung
Vector boson fusion
Vector boson fusion
Top fusion
Top fusion
If Higgs particle theories are correct, then a Higgs particle can be produced much like other particles that are studied, in a particle collider. This involves accelerating a large number of particles to extremely high energies and extremely close to the speed of light, then allowing them to smash together. Protons and lead ions (the bare nuclei of lead atoms) are used at the LHC. In the extreme energies of these collisions, the desired esoteric particles will occasionally be produced and this can be detected and studied; any absence or difference from theoretical expectations can also be used to improve the theory. The relevant particle theory (in this case the Standard Model) will determine the necessary kinds of collisions and detectors.
The Standard Model predicts that Higgs bosons could be formed in a number of ways,[95][96][97] although the probability of producing a Higgs boson in any collision is always expected to be very small—for example, only 1 Higgs boson per 10 billion collisions in the Large Hadron Collider.[Note 13] The most common expected processes for Higgs boson production are:
  • Gluon fusion. If the collided particles are hadrons such as the proton or antiproton—as is the case in the LHC and Tevatron—then it is most likely that two of the gluons binding the hadron together collide. The easiest way to produce a Higgs particle is if the two gluons combine to form a loop of virtual quarks. Since the coupling of particles to the Higgs boson is proportional to their mass, this process is more likely for heavy particles. In practice it is enough to consider the contributions of virtual top and bottom quarks (the heaviest quarks). This process is the dominant contribution at the LHC and Tevatron being about ten times more likely than any of the other processes.[95][96]
  • Higgs Strahlung. If an elementary fermion collides with an anti-fermion—e.g., a quark with an anti-quark or an electron with a positron—the two can merge to form a virtual W or Z boson which, if it carries sufficient energy, can then emit a Higgs boson. This process was the dominant production mode at the LEP, where an electron and a positron collided to form a virtual Z boson, and it was the second largest contribution for Higgs production at the Tevatron. At the LHC this process is only the third largest, because the LHC collides protons with protons, making a quark-antiquark collision less likely than at the Tevatron. Higgs Strahlung is also known as associated production.[95][96][97]
  • Weak boson fusion. Another possibility when two (anti-)fermions collide is that the two exchange a virtual W or Z boson, which emits a Higgs boson. The colliding fermions do not need to be the same type. So, for example, an up quark may exchange a Z boson with an anti-down quark. This process is the second most important for the production of Higgs particle at the LHC and LEP.[95][97]
  • Top fusion. The final process that is commonly considered is by far the least likely (by two orders of magnitude). This process involves two colliding gluons, which each decay into a heavy quark–antiquark pair. A quark and antiquark from each pair can then combine to form a Higgs particle.[95][96]

Decay

The Standard Model prediction for the decay width of the Higgs particle depends on the value of its mass.

Quantum mechanics predicts that if it is possible for a particle to decay into a set of lighter particles, then it will eventually do so.[99] This is also true for the Higgs boson. The likelihood with which this happens depends on a variety of factors including: the difference in mass, the strength of the interactions, etc. Most of these factors are fixed by the Standard Model, except for the mass of the Higgs boson itself. For a Higgs boson with a mass of 126 GeV/c2 the SM predicts a mean life time of about 1.6×10−22 s.[Note 2]
The Standard Model prediction for the branching ratios of the different decay modes of the Higgs particle depends on the value of its mass.

Since it interacts with all the massive elementary particles of the SM, the Higgs boson has many different processes through which it can decay. Each of these possible processes has its own probability, expressed as the branching ratio; the fraction of the total number decays that follows that process. The SM predicts these branching ratios as a function of the Higgs mass (see plot).
One way that the Higgs can decay is by splitting into a fermion–antifermion pair. As general rule, the Higgs is more likely to decay into heavy fermions than light fermions, because the mass of a fermion is proportional to the strength of its interaction with the Higgs.[101] By this logic the most common decay should be into a top–antitop quark pair. However, such a decay is only possible if the Higgs is heavier than ~346 GeV/c2, twice the mass of the top quark. For a Higgs mass of 126 GeV/c2 the SM predicts that the most common decay is into a bottom–antibottom quark pair, which happens 56.1% of the time.[100] The second most common fermion decay at that mass is a tau–antitau pair, which happens only about 6% of the time.[100]

Another possibility is for the Higgs to split into a pair of massive gauge bosons. The most likely possibility is for the Higgs to decay into a pair of W bosons (the light blue line in the plot), which happens about 23.1% of the time for a Higgs boson with a mass of 126 GeV/c2.[100] The W bosons can subsequently decay either into a quark and an antiquark or into a charged lepton and a neutrino. However, the decays of W bosons into quarks are difficult to distinguish from the background, and the decays into leptons cannot be fully reconstructed (because neutrinos are impossible to detect in particle collision experiments). A cleaner signal is given by decay into a pair of Z-bosons (which happens about 2.9% of the time for a Higgs with a mass of 126 GeV/c2),[100] if each of the bosons subsequently decays into a pair of easy-to-detect charged leptons (electrons or muons).

Decay into massless gauge bosons (i.e., gluons or photons) is also possible, but requires intermediate loop of virtual heavy quarks (top or bottom) or massive gauge bosons.[101] The most common such process is the decay into a pair of gluons through a loop of virtual heavy quarks. This process, which is the reverse of the gluon fusion process mentioned above, happens approximately 8.5% of the time for a Higgs boson with a mass of 126 GeV/c2.[100] Much rarer is the decay into a pair of photons mediated by a loop of W bosons or heavy quarks, which happens only twice for every thousand decays.[100] However, this process is very relevant for experimental searches for the Higgs boson, because the energy and momentum of the photons can be measured very precisely, giving an accurate reconstruction of the mass of the decaying particle.[101]

Richard Dawkins talks about GMO crops

Richard Dawkins talks about GMO crops


Richard_Dawkins_Cooper_Union_Shankbone
For New Year’s Day, I’m republishing the top 10 articles I wrote in 2013. Well, actually top 9, plus 1 from 2012 that just keeps going.
#2. This article was published on 12 June 2013, and has had nearly 40,000 views. GMO’s cause so much unscientific drama, that when Richard Dawkins, a “saint” for the a lot of pro-science people, makes it known that being against GMO’s is anti-science, it causes the time-space continuum to break. 

Thirteen years ago, Richard Dawkins, noted secularist, author and evolutionary biologist, wrote an open letter to Prince Charles, noted promoter of pseudoscience and heir apparent to the British throne, about the Prince’s hostility to science. Even though the letter was written more than a decade ago, the salient points still ring true today:
…Sir, I think you may have an exaggerated idea of the natural-ness of ‘traditional’ or ‘organic’ agriculture. Agriculture has always been unnatural. Our species began to depart from our natural hunter-gatherer lifestyle as recently as 10,000 years ago – too short to measure on the evolutionary timescale.
Wheat, be it ever so wholemeal and stoneground, is not a natural food for Homo sapiens. Nor is milk, except for children. Almost every morsel of our food is genetically modified – admittedly by artificial selection not artificial mutation, but the end result is the same. A wheat grain is a genetically modified grass seed, just as a pekinese is a genetically modified wolf. Playing God? We’ve been playing God for centuries!
Wheat was domesticated around 11,000 years ago (but some forms of wheat may have been domesticated 25,000 years ago). Part of the domestication process was forcing it into tetraploidy (4 sets of chromosomes) or hexaploidy (6 sets of chromosomes). Corn was domesticated 7500-10,000 years ago in central America from a plant, still extant in that area, teosintes, which looks like grass. If you walked by a teosintes plant, you would probably not think it was corn.

Plants like legumes (peanuts, beans and other similar crops) incorporate Rhizobia bacteria in their roots to fix nitrogen from the atmosphere for nutrition for the plant. According to the Endosymbiotic theory of evolution, mitochondria and chloroplasts, important cellular structures for most organisms, were free-living organisms incorporated by other cells. In other words, genetic and cellular modification of organisms have been happening for billions of years. Unless you ascribe to the Naturalistic Fallacy, which states only natural things are “good”, the differences between human modification of the genome and so-called “natural” ones are nonexistent.

But let’s continue with Dawkins’ letter.
The large, anonymous crowds in which we now teem began with the agricultural revolution, and without agriculture we could survive in only a tiny fraction of our current numbers. Our high population is an agricultural (and technological and medical) artifact. It is far more unnatural than the population-limiting methods condemned as unnatural by the Pope. Like it or not, we are stuck with agriculture, and agriculture – all agriculture – is unnatural. We sold that pass 10,000 years ago.
Does that mean there’s nothing to choose between different kinds of agriculture when it comes to sustainable planetary welfare? Certainly not. Some are much more damaging than others, but it’s no use appealing to ‘nature’, or to ‘instinct’ in order to decide which ones. You have to study the evidence, soberly and reasonably – scientifically. Slashing and burning (incidentally, no agricultural system is closer to being ‘traditional’) destroys our ancient forests. Overgrazing (again, widely practised by ‘traditional’ cultures) causes soil erosion and turns fertile pasture into desert. Moving to our own modern tribe, monoculture, fed by powdered fertilisers and poisons, is bad for the future; indiscriminate use of antibiotics to promote livestock growth is worse.
Once again, the Appeal to Nature logical fallacy has no meaning. Natural is not better, especially if the “natural” system was lost thousands of years ago. As Dawkins says, maybe some parts of agriculture need to be fixed, but if by fixing we actually mean “let’s go back to the way it was”, that’s a long way back, and it’s going to starve a lot of people just for a belief rather than science.
Incidentally, one worrying aspect of the hysterical opposition to the possible risks from GM crops is that it diverts attention from definite dangers which are already well understood but largely ignored. The evolution of antibiotic-resistant strains of bacteria is something that a Darwinian might have foreseen from the day antibiotics were discovered. Unfortunately the warning voices have been rather quiet, and now they are drowned by the baying cacophony: ‘GM GM GM GM GM GM!’
Moreover if, as I expect, the dire prophecies of GM doom fail to materialise, the feeling of let-down may spill over into complacency about real risks. Has it occurred to you that our present GM brouhaha may be a terrible case of crying wolf?
And it’s crying wolf, when there is no evidence that the wolf was even here. That’s the worst part. There isn’t even a pretend wolf running around. Not even a picture of a wolf.
Even if agriculture could be natural, and even if we could develop some sort of instinctive rapport with the ways of nature, would nature be a good role model? Here, we must think carefully. There really is a sense in which ecosystems are balanced and harmonious, with some of their constituent species becoming mutually dependent. This is one reason the corporate thuggery that is destroying the rainforests is so criminal.
On the other hand, we must beware of a very common misunderstanding of Darwinism. Tennyson was writing before Darwin but he got it right. Nature really is red in tooth and claw. Much as we might like to believe otherwise, natural selection, working within each species, does not favour long-term stewardship. It favours short-term gain. Loggers, whalers, and other profiteers who squander the future for present greed, are only doing what all wild creatures have done for three billion years. 
No wonder T.H. Huxley, Darwin’s bulldog, founded his ethics on a repudiation of Darwinism. Not a repudiation of Darwinism as science, of course, for you cannot repudiate truth. But the very fact that Darwinism is true makes it even more important for us to fight against the naturally selfish and exploitative tendencies of nature. We can do it. Probably no other species of animal or plant can. We can do it because our brains (admittedly given to us by natural selection for reasons of short-term Darwinian gain) are big enough to see into the future and plot long-term consequences. Natural selection is like a robot that can only climb uphill, even if this leaves it stuck on top of a measly hillock. There is no mechanism for going downhill, for crossing the valley to the lower slopes of the high mountain on the other side. There is no natural foresight, no mechanism for warning that present selfish gains are leading to species extinction – and indeed, 99 per cent of all species that have ever lived are extinct.
The human brain, probably uniquely in the whole of evolutionary history, can see across the valley and can plot a course away from extinction and towards distant uplands. Long-term planning – and hence the very possibility of stewardship – is something utterly new on the planet, even alien. It exists only in human brains. The future is a new invention in evolution. It is precious. And fragile. We must use all our scientific artifice to protect it.
Dawkins is making a critical point here. To make the earth better, to feed the people, to deal with “nature”, we actually have to behave against nature, because…
It may sound paradoxical, but if we want to sustain the planet into the future, the first thing we must do is stop taking advice from nature. Nature is a short-term Darwinian profiteer. Darwin himself said it: ‘What a book a devil’s chaplain might write on the clumsy, wasteful, blundering, low, and horridly cruel works of nature.’ 
Of course that’s bleak, but there’s no law saying the truth has to be cheerful; no point shooting the messenger – science – and no sense in preferring an alternative world view just because it feels more comfortable. In any case, science isn’t all bleak. Nor, by the way, is science an arrogant know-all. Any scientist worthy of the name will warm to your quotation from Socrates: ‘Wisdom is knowing that you don’t know.’ What else drives us to find out?
I know that some of the anti-GMO argument is based on poor evidence published in junk science journals with low impact factor. But a big chunk of the anti-GMO crowd has this belief that somehow the world was better 50, 100, 200 years ago. It wasn’t. I participated in a discussion where people were making a claim that cancers and childhood mortality have somehow increased over the past few decades. But, that’s just not true.

The doors have been opened to GMO crops 10,000 years ago. There is no way to go back in time, unless some of you know something that the rest of us don’t. We cannot possibly feed the world without specialized crops that can grow to be pest-restistent, drought-tolerant, or whatever we need.
Science isn’t perfect, so there might be errors along the way, but in general, they will be minor mistakes, and the greatest thing about science is that it is completely self-correcting. If we “design” a corn that costs too much, we design a better one.

Genetic engineering is a fact of life. Millions of people are kept alive with genetically engineered insulin, that is the human insulin gene is inserted into bacteria so that factories can produce billions of vials of the important hormone. Without it, a Type 1 diabetic will die painfully and sadly within a few days. Before the 1980′s, insulin was extracted from pig pancreas, because it was close enough. But it didn’t work as well as human insulin. And there were all kinds of allergic reactions. If you want to go back in time to a more natural world, a child with diabetes would die. And that doesn’t seem like a good choice.

If, like Prince Charles, your argument is going to be based on Appeals to Nature or the Naturalistic Fallacy or the Nirvana Fallacy. Or if your argument is going to use terrible science that wouldn’t meet the standards of a high school science fair by publishing a paper about pigs being less healthy on a GMO diet, but it’s in a horrible journal because no respectable journal would publish such an incredibly bad study. Or if you’re going to use a strawman by bashing Monsanto 24/7. Well, then we’re not going to improve the world. We’re not going to feed the 10 billion people that will be on the planet in just a few years. Instead, by just yelling out that GMO’S ARE EVIL, with no evidence whatsoever, just makes most of us with a science background shrug our shoulders and proceed. As long as there’s no evidence that GMO’s are dangerous, as long as we need to feed people, we just move ahead.

There are discussions that need to be a part of the GMO discourse. Biodiversity is one, but I’m not even convinced as of yet that that is an issue. Agriculture is not about biodiversity, it’s about maximizing the amount of food calories produced per acre. There are more efficient and, frankly, effective ways of protecting biodiversity. But screaming about how bad they are, well, that’s going to lead us nowhere.

There is a discussion that needs to be made about genetically modified crops. Richard Dawkins said so 13 years ago. Unfortunately, all we get are science deniers who keep saying “GMO’s are bad”, when there is a more nuanced and important discussion to be had. But it’s just so hard to deal with science denialist because, as Sam Harris once said:
Water is two parts hydrogen and one part oxygen. What if someone says, “Well, that’s not how I choose to think about water”? All we can do is appeal to scientific values. And if he doesn’t share those values, the conversation is over. If someone doesn’t value evidence, what evidence are you going to provide to prove they should value it? If someone doesn’t value logic, what logical argument could you provide to show the importance of logic?
It’s hard to have a rational discussion with the anti-GMO crowd. They don’t share our values in the importance of science and how to accumulate evidence.

One more thing. There’s really no black and white to the GMO discussion. Except that one side keeps saying “it’s only black” leaving little room for those of us who think it’s white with some grey streaks here and there. Maybe someone will listen to Dawkins. Because Prince Charles hasn’t.
Note: Link to full text of the letter.

Tuesday, August 5, 2014

It's precisely this power that makes Showalter's biomedical research possible.

Scientist uses giant spectrometer to search for cure for cancer

Scientist uses giant spectrometer to search for cure for cancer
Scott Showalter, a researcher and associate professor of chemistry, in his lab in the Chemistry Building. Credit: Lauren Ingram
A pro at navigating the labyrinthine hallways in the Chemistry Building, Scott Showalter, researcher and associate professor of chemistry in Penn State's Eberly College of Science, maneuvers from his office, class and a handful of laboratories throughout the day. But it's one workspace in particular, home to the ScholarSphere, a drum-shaped hunk of machinery—essentially a gigantic MRI on stilts—where Showalter is moving closer to the biomedical breakthrough he so desires.

Showalter wants to help find a cure for cancer.

By harnessing the power of the mammoth instrument, a nuclear magnetic resonance (NMR) spectrometer, he is able to study the chemical structures of invisible-to-the-eye atoms stored in vials no larger than ballpoint pens.

The irony of the disproportion is not lost on him.

"We're using this gigantic machine to fine-tune new methods for studying disordered proteins of microscopic proportions—of which 70 percent can be disease causing," Showalter said.

Proteins are important to health because they regulate gene expression and execute cell function, which can, for example, play a role in determining whether or not a pancreas creates enough insulin or if a cellular mutation will become cancerous.

"These disordered proteins are too small to study under a microscope, but the behavior of the infinitesimal magnets in the atoms that comprise the proteins are the key to our work," Showalter explained. "So, we're putting the atoms in the presence of the biggest magnet we can find to get them dancing: a NMR spectrometer."

The spectrometer uses an ultrastrong magnet and radio frequency circuitry similar to an FM radio to analyze the atom's structure in ways other tools can't.

Scientist uses giant spectrometer to search for cure for cancer
Showalter uses a nuclear magnetic resonance (NMR) spectrometer to fine-tune new methods for studying disordered proteins. Credit: Lauren Ingram
Used by Penn State scientists for all kinds of research, the spectrometer packs a punch so strong—emitting a magnetic field nearly half a million times stronger than that of the earth below State College—that any smartphone, laptop or pacemaker that comes within its vicinity is fried.
It's precisely this power that makes Showalter's possible.

By developing original methods for understanding these intrinsically disordered proteins (a relatively new field of biochemistry), Showalter and his team can provide researchers around the world with the knowledge and resources they need to design drug targets for treating such maladies as cancer, diabetes and hepatitis C.

"Unlike the other two-thirds of the proteins in our bodies, these disordered proteins are constantly changing form. At this point, scientists don't understand them well enough to efficiently design drug molecules that can interact with them," said Showalter. "Our primary goal is to understand them better on a fundamental level because the process of finding a drug is either going to be a very expensive, unguided fishing expedition or a well-informed, strategic collaboration."
As one of the preliminary steps in this process, Showalter and his team are not only writing the code for and running the new experiments; they also are sharing their potentially life-saving findings with the world.

"Developing the code to conduct experiments on the NMR spectrometer is not easy. There are many, many scientists who are capable of using these instruments but who don't consider themselves to be code developers," Showalter said. "We're broadly disseminating data files other people can upload to their NMR spectrometers so they can do the experiments, too."
As part of his for publicly disseminating his research findings (a mandate of his National Science Foundation grant), Showalter shares the results of his original experiments in research journals and also uploads the code for the experiments into ScholarSphere, Penn State's digital repository for curating and preserving research and scholarly data.

Scientist uses giant spectrometer to search for cure for cancer
The atoms Showalter and his team study are placed in vials the sizes of ballpoint pens and tested in the NMR spectrometer. Credit: Lauren Ingram

By openly sharing the original experiments with scientists around the world using the repository service, Showalter and his team are widening the net of researchers who can use the same NMR techniques to conduct their own biomedical research.
So far, it's working.

After reading a paper written by Showalter and team in the Journal of Physical Chemistry Letters, which linked to the experiment's code in ScholarSphere, a scientist at the Scripps Research Institute in Florida downloaded the data set and reached out to Showalter with some follow-up questions.

Scientist uses giant spectrometer to search for cure for cancer
Bastidas prepares a sample for the spectrometer. Credit: Penn State
It's having this kind of broad impact that gets Showalter out of bed in the morning.
"Our field is growing really quickly, and it's been a lot of fun to be part of a new area of biochemistry and to be able to make major contributions with a technique that I care about. It has been pretty inspiring," Showalter said. "I'm not a medical doctor, so anything that we might be able to do that can influence biomedicine and build bridges to the doctors and nurses who have a direct effect on a patient's health is my goal. I can't get there on my own, but hopefully together, we can help make innovations happen faster."
Explore further: Minuscule chips for NMR spectroscopy promise portability, parallelization

Waldorf education

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