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Sunday, April 27, 2025

Child mortality

From Wikipedia, the free encyclopedia
Share of children born alive that die before the age of 5 (2017)
Breakdown of child mortality by cause, OWID

Child mortality is the death of children under the age of five. The child mortality rate (also under-five mortality rate) refers to the probability of dying between birth and exactly five years of age expressed per 1,000 live births.

It encompasses neonatal mortality and infant mortality (the probability of death in the first year of life).

Reduction of child mortality is reflected in several of the United Nations' Sustainable Development Goals. Target 3.2 states that "by 2030, the goal is to end preventable deaths of newborns and children under 5 years of age with all countries aiming to reduce under‑5 mortality to as low as 25 per 1,000 live births."

Child mortality rates have decreased in the last 40 years. Rapid progress has resulted in a significant decline in preventable child deaths since 1990 with the global under-5 mortality rate declining by over half between 1990 and 2016. While in 1990, 12.6 million children under age five died and in 2016, that number fell to 5.6 million children and then in 2020, the global number fell again to 5 million. However, despite advances, there are still 15,000 under-five deaths per day from largely preventable causes. About 80 percent of these occur in sub-Saharan Africa and South Asia and just 6 countries account for half of all under-five deaths: China, India, Pakistan, Nigeria, Ethiopia and the Democratic Republic of the Congo. 45% of these children died during the first 28 days of life. Death rates were highest among children under age 1, followed by children ages 15 to 19, 1 to 4 and 5 to 14.

Types of Child Mortality

Child mortality refers to number of child deaths under the age of 5 per 1,000 live births. More specific terms include:

  • Perinatal mortality rate: Number of child deaths within the first week of birth divided by total number of births.
  • Neonatal mortality rate: Number of child deaths within the first 28 days of life divided by total number of births.
  • Infant mortality rate: Number of child deaths within the first 12 months of life divided by total number of births.
  • Under 5 mortality rates: Number of child deaths within the 5th birthday divided by total number of births.
  • Child Mortality refers to the premature deaths of any child under the age of 5 years old. However, within those 5 years, there are 5 smaller groups. Perinatal refers to a fetus, a living organism, but not yet born. Typically, peri neonate deaths are due to premature birth or birth defects. Neonatal refers to child death within one month or 28 days of birth. Neonate deaths are reflected in the type of care the hospital is providing as well as birth defects and complications. Infant death refers to the death of a child before their first birthday or within 12 months of life. Some of the main causes include premature birth, SIDS, low birth weight, malnutrition and infectious diseases. And lastly, the under-5 mortality rate refers to children who die under the age of 5 years old or within the first 5 years of life.

Causes

The leading causes of death of children under five include:

There is variation of child mortality around the world. Countries that are in the second or third stage of the Demographic Transition Mode (DTM) have higher rates of child mortality than countries in the fourth or fifth stage. Chad infant mortality is about 96 per 1,000 live births compared to only 2.2 per 1,000 live births in Japan. In 2010, there was a global estimate of 7.6 million child deaths especially in less developed countries and among those, 4.7 million died from infection and disorder. Child mortality is not only caused by infection and disorder, it is also caused by premature birth, birth defect, new born infection, birth complication and diseases like malaria, sepsis, and diarrhea. In less developed countries, malnutrition is the main cause of child mortality. Pneumonia, diarrhea and malaria together are the cause of one out of every three deaths before the age of 5 while nearly half of under-five deaths globally are attributable to under-nutrition.

Prevention

Child survival is a field of public health concerned with reducing child mortality. Child survival interventions are designed to address the most common causes of child deaths that occur, which include diarrhea, pneumonia, malaria, and neonatal conditions. Out of the number of children under the age of 5 alone, an estimated 5.6 million children die each year mostly from such preventable causes.

The child survival strategies and interventions are in line with the fourth Millennium Development Goals (MDGs) which focused on reducing child mortality by 2/3 of children under five before the year 2015. In 2015, the MDGs were replaced with the Sustainable Development Goals (SDGs) which aim to end these deaths by 2030. In order to achieve SDG targets, progress must be accelerated in more than 1/4 of all countries (most of which are in sub-Saharan Africa) in order to achieve targets for under-5 mortality and in 60 countries (many in sub-Saharan Africa and South Asia) to achieve targets for neonatal mortality. Without accelerated progress, 60 million children under age five will die between 2017 and 2030, about half of which would be newborns. China achieved its target of reduction in under-5 mortality rates well ahead of schedule.

Low-cost interventions

Child sits with a doctor to receive medical care

Two-thirds of child deaths are preventable. Most of the children who die each year could be saved by low-tech, evidence-based, cost-effective measures such as vaccines, antibiotics, micronutrient supplementation, insecticide-treated bed nets, improved family care and breastfeeding practices, and oral rehydration therapy. Empowering women, removing financial and social barriers to accessing basic services, developing innovations that make the supply of critical services more available to the poor and increasing local accountability of health systems are policy interventions that have allowed health systems to improve equity and reduce mortality.

In developing countries, child mortality rates related to respiratory and diarrheal diseases can be reduced by introducing simple behavioral changes such as handwashing with soap. This simple action can reduce the rate of mortality from these diseases by almost 50 per cent.

Proven cost-effective interventions can save the lives of millions of children per year. The UN Vaccine division as of 2014 supported 36% of the world's children in order to best improve their survival chances, yet still, low-cost immunization interventions do not reach 30 million children despite success in reducing polio, tetanus, and measles. Measles and tetanus still kill more than 1 million children under 5 each year. Vitamin A supplementation costs only $0.02 for each capsule and given 2–3 times a year will prevent blindness and death. Although vitamin A supplementation has been shown to reduce all-cause mortality by 12 to 24 per cent but only 70 per cent of targeted children were reached in 2015. Between 250,000 and 500,000 children become blind every year with 70 percent of them dying within 12 months. Oral rehydration therapy (ORT) is an effective treatment for lost liquids through diarrhea; yet only 4 in 10 (44 per cent) of children diagnosed with diarrhea are treated with ORT.

Essential newborn care - including immunizing mothers against tetanus, ensuring clean delivery practices in a hygienic birthing environment, drying and wrapping the baby immediately after birth, providing necessary warmth and promoting immediate and continued breastfeeding, immunization, and treatment of infections with antibiotics - could save the lives of 3 million newborns annually. Improved sanitation and access to clean drinking water can reduce childhood infections and diarrhea. As of 2017, approximately 26% of the world's population do not have access to basic sanitation and 785 million people use unsafe sources of drinking water.

Efforts

Agencies promoting and implementing child survival activities worldwide include UNICEF and non-governmental organizations; major child survival donors worldwide include the World Bank, the British Government's Department for International Development, the Canadian International Development Agency and the United States Agency for International Development. In the United States, most non-governmental child survival agencies belong to the CORE Group, a coalition working through collaborative action to save the lives of young children in the world's poorest countries.

Substantial global progress has been made in reducing child deaths since 1990. The total number of under-5 deaths worldwide has declined from 12.6 million in 1990 to approximately 5.5 million in 2020. Since 1990, the global under-5 mortality rate has dropped by 59%, from 93 deaths per 1000 live births in 1990 to 36 in 2020. This is equivalent to 1 in 11 children dying before reaching age 5 in 1990 compared to 1 in 27 in 2019. The Sustainable Development Goals has set 2 new goals to reduce under-5 and newborn mortality. The goals set newborn mortality for 12 per 1,000 live births in every country and for under 5 mortality 25 per 1,000 livebirths in every country. In 2019, 122 countries met this and every 10 years, 20 more are expected to follow. World Health Organization (WHO) states they support health equity and universal health care so that all countries may have proper health care with no finances involved.

Epidemiology

Mortality in the first five years of life from 1960 to 2017.

Child mortality has been dropping as each country reaches a high stage of DTM. From 2000 to 2010, child mortality has dropped from 9.6 million to 7.6 million. In order to reduce child mortality rates, there need to be better education, higher standards of healthcare and more caution in childbearing. Child mortality could be reduced by attendance of professionals at birth and by breastfeeding and through access to clean water, sanitation, and immunization. In 2016, the world average was 41 (4.1%), down from 93 (9.3%) in 1990. This is equivalent to 5.6 million children less than five years old dying in 2016.

Variation

Huge disparities in under-5 mortality rates exist. Globally, the risk of a child dying in the country with the highest under-5 mortality rate is about 60 times higher than in the country with the lowest under-5 mortality rate. Sub-Saharan Africa remains the region with the highest under-5 mortality rates in the world: All six countries with rates above 100 deaths per 1,000 live births are in sub-Saharan Africa, with Somalia having the highest under-5 mortality rates.

Furthermore, approximately 80% of under-5 deaths occur in only two regions: sub-Saharan Africa and South Asia. 6 countries account for half of the global under-5 deaths, namely, India, Nigeria, Pakistan, the Democratic Republic of the Congo, Ethiopia and China. India and Nigeria alone account for almost a third (32 per cent) of the global under-five deaths. Within low- and middle-income countries, there is also substantial variation in child mortality rates across administrative divisions.

Likewise, there are disparities between wealthy and poor households in developing countries. According to a Save the Children paper, children from the poorest households in India are three times more likely to die before their fifth birthday than those from the richest households. A systematic study reports for all the low- and middle-income countries (not including China), the children among the poorest households are twice as likely to die before the age of 5 years old compare to those in the richest household.

A large team of researchers published a major study on the global distribution of child mortality in Nature in October 2019. It was the first global study that mapped child death on the level of subnational district (17,554 units). The study was described as an important step to make action possible that further reduces child mortality.

The child survival rate of nations varies with factors such as fertility rate and income distribution; the change in distribution shows a strong correlation between child survival and income distribution as well as fertility rate where increasing child survival allows the average income to increase as well as the average fertility rate to decrease.

COVID-19 and child mortality

Child mortality unlike mortality throughout other ages actually dropped in 2020 when the COVID-19 pandemic hit the world. Children were among the lowest group of deaths in the world due to COVID-19. About 3.7 million deaths occurred and only 0.4% of them occurred in adolescents under 20 years of age making about 13,400 deaths in adolescents. Out of that small proportion, 42% occurred in children under the age of 9 years old.

Exploitation of natural resources

From Wikipedia, the free encyclopedia
https://en.wikipedia.org/wiki/Exploitation_of_natural_resources

Natural resources, often non-renewable or limited, can be taken advantage of in an unethical manner ('exploited') for economic growth or development. Environmental degradation, human insecurity, and social conflict frequently accompany natural resource exploitation. The impacts of the depletion of natural resources include the decline of economic growth in local areas; however, the abundance of natural resources does not always correlate with a country's material prosperity. Many resource-rich countries, especially in the Global South, face distributional conflicts, where local bureaucracies mismanage or disagree on how resources should be used. Foreign industries also contribute to resource exploitation, where raw materials are outsourced from developing countries, with the local communities receiving little profit from the exchange. This is often accompanied by negative effects of economic growth around the affected areas such as inequality and pollution

The exploitation of natural resources started to emerge on an industrial scale in the 19th century as the extraction and processing of raw materials (such as in mining, steam power, and machinery) expanded much further than it had in pre-industrial areas. During the 20th century, energy consumption rapidly increased. Today, about 80% of the world's energy consumption is sustained by the extraction of fossil fuels, which consists of oil, coal and natural gas.

Another non-renewable resource humans exploit is subsoil minerals, such as precious metals, mainly used to produce industrial commodities. Intensive agriculture is an example of a mode of production that hinders many aspects of the natural environment, for example the degradation of forests in a terrestrial ecosystem and water pollution in an aquatic ecosystem. As the world population rises and economic growth occurs, the depletion of natural resources influenced by the unsustainable extraction of raw materials becomes an increasing concern. The continuous alteration of the environment through water, mineral, and forest exploitation poses increased risks of climate-based displacement and conflict stemming from scarcity, which threaten to perpetuate social inequities.

Revenue from mineral exports makes up a large portion of the Democratic Republic of Congo's economy. While Congo is rich in mineral resources, these deposits require extensive manual labor to extract, often under life-threatening conditions. Mining of cobalt is leading to human rights being abused in ways such as unsafe worksites, child labor, and forced Congolese labor, in addition to environmental degradation.

Causes

  • Advancing technology: Increasing technology sophistication enables faster rates of natural resource extraction. For example, in the past, it could take a long time to log a small amount of trees using only saws. Due to better technology, the rates of deforestation have greatly increased.
  • Overconsumption has created a high demand for natural resources, further exacerbating natural resource exploitation 
  • Development of new technologies, such as electric vehicles and portable technologies, i.e, Smartphones, also heavily rely on cobalt mining, often leading to loss of green cover and detrimental health impacts for surrounding communities, often in developing countries like the D.R. of Congo where mining occurs.
  • Consumerism: Unsustainable consumption, driven by both population growth and materialistic ideologies, increases the demand for production and, thereby, the extraction of the natural resources needed to supply this demand. For instance, the consumption of fine jewelry leads to increased mining of gold and diamonds. The extraction of precious metals like gold has degradation effects on the environment, such as loss of forestry during construction of the mining facilities, increased exposure to toxic materials, and disturbance of the nearby ecosystem.
  • Management thinking: In relation to the previous point, companies have adopted the idea according to which the rarer the resource, the more it contributes to the company's competitive advantage. When it comes to natural resources, such an idea leads to natural resource exhaustion.
  • A general lack of respect for native land rights leads to increased exploitation of natural resources on and around native land.

Consequences of exploitation of resources

A group of people in blue shirts walking across a field with multiple piles of branches.
A deforestation in Nigeria team patrolling the deforestation site. Nigeria has experienced an increase in deforestation in part due to expansion of agriculture, lumbering, and urban growth. These land-use changes are driven by population increase and poverty.

Natural resources are not limitless, and the following consequences can arise from the careless and excessive consumption of these resources:

  • Deforestation: Removal of trees for use as resources, such as in agriculture or industry, can lead to large-scale destruction of forests. Around 40% of the Earth's original forest cover has been lost in the last 8000 years.
  • Desertification: Human-led changes in land management practices lead to changes in the ecological characteristics of a region. Land mismanagement and climate change can lead to a loss of ecosystem services, such as through degradation of soil. Together, these losses can result in desertification seen in arid and dry areas.
  • Decrease in natural resources: When resources are exploited faster than they can be replenished, it results in an overall decrease in natural resources in an area.
  • Extinction of species: Processes involved in resource exploitation can directly or indirectly lead to the extinction of species. Animals used for resources can be directly hunted, while destruction of environments, such as through harvesting timber, can also cause extinctions.
  • Forced migration
  • Soil erosion
  • Oil depletion
  • Ozone depletion
  • Greenhouse gas increase
  • Water gasification
  • Natural hazard/Natural disaster
  • Metals and minerals depletion.
  • Indigenous groups have limited ways to relate to the environment and survive on traditional food and water sources 

Economic consequences

Natural resources are vital for human survival, however, if their consumption surpasses their natural replenishment rate, the resources can become depleted. According to the United Nations Food and Agriculture Organization, around 33% of the Earth's soils are presently classified as moderately to highly degraded, with projections indicating that more than 90% could face degradation by the year 2050 and thus cause significant economic consequences. With such rate of erosion of fertile soil, agricultural commodity prices tend to increase significantly. The connection between the consumption rate and the supply rate of resources holds significant implications for long-term economic growth, as sustained high consumption rates of certain resources ultimately jeopardize economic sustainability. For instance, in the case of extracting soil minerals, supply rate is exceedingly slow over geological time spans, inevitably leading to a consumption rate surpassing the supply rate. Such a scenario is evidently unsustainable in the long run. To ensure sustainability, the consumption rate must remain equal to or less than the supply rate.

There has been an ongoing debate among scholars and researchers on the economic implications of dependence on natural resources. Natural resources yield economic rents that can be allocated towards public welfare initiatives and other projects beneficial to local communities. However, in the long term, uncertainties linked to potentially unstable terms of trade for commodities might lead to decline in public finances and deter investment. For instance, if oil prices decline, it may lead to fiscal unease in significant petroleum-producing countries such as Russia, Qatar, and Saudi Arabia. Resource abundance challenges the progress of political and governance institutions by nurturing a culture of rentierism. For instance, revenues obtained from resources can be used for political manipulation. Additionally, extra capital from resources can dilute government accountability to both citizens and businesses by abandoning taxation completely, which leads to lack of government incentive to support economic growth through innovation. At the same time, citizens may lack the motives to advocate for better governance and transparency.

Because of environmental pollution, cities whose economies rely on natural resources face difficulties in attracting technology-driven businesses and skilled labor, posing significant challenges to their economic transformation and advancement. These resource-centric cities face disadvantages in the competition among local governments striving for environmental quality. Analyzing panel data spanning from 2005 to 2017 for 30 coal-mining cities, it's been discovered that environmental regulations offer a new approach to potentially reversing the adverse effects of resource dependence, and thus fueling greener sustainable development in coal-mining regions.

Despite the inevitability of environmental contamination associated with resource extraction because of current mining technologies, this pollution delays residents' engagement in agricultural and aqua cultural activities, which are negatively influenced by environmental conditions. As a result, these cities tend to rely heavily on a singular economic development model centered around resource exploitation, making them ill-equipped to address environmental crises effectively. Economic gains from natural resources are mostly beneficial when directed towards initiatives such as job creation, skill enhancement, capacity building, and pursuit of long-term developmental objectives. Thus, reliance on one or more natural resources holds financial risk when aiming for a stable economic growth.

Impacts of settler colonialism

Multiple scholars have explained how Settler colonialism has had profound influence on the dynamics of resource exploitation throughout history, especially in regions where settler populations have previously asserted dominance over indigenous peoples and their territories. Among these scholars Dina Gilio-Whitaker, an expert in Native American Studies from California State University explains that, “Indigenous peoples fighting for political autonomy from the hegemony of the State are fighting the forces of colonialism while simultaneously fighting capitalism—all aimed at control of land and resources" This encompasses the establishment of permanent settler communities, typically accompanied by the displacement, marginalization, or even extermination of indigenous populations. Settler Colonial exploration is most often driven by the pursuit of land and resources which has historically created the exploitation of natural wealth to fuel economic growth, infrastructure development, and territorial expansion.

One of the key way which settler colonialism drives resource exploitation is through the appropriation of indigenous lands and natural resources. Kyle Powys Whyte, an expert in natural resources and the environment highlights how the continued legacy of settler colonialism continues to harm indigenous communities. In his piece “The Dakota Access Pipeline, Environmental Injustice, and US Settler Colonialism” he writes, “as climate change becomes more apparent in its homelands, the shifting plant and animal habitats tied to agriculture, wildlife, and ceremonial species, as well as the loss of territory and resources as a result of US settler colonialism, will make it harder to adjust.”

Settler societies often view the land as a commodity to be exploited for economic gain, leading to the establishment of extractive industries such as mining, logging, and agriculture on indigenous territories. This exploitation is facilitated by legal frameworks that prioritize settler property rights over indigenous land tenure systems, resulting in the dispossession and displacement of indigenous communities from their ancestral lands. Moreover, settler colonialism often entails the imposition of Western concepts of land ownership and resource management that marginalize indigenous knowledge and practices, further exacerbating environmental degradation and social injustice.

Dakota Access Pipeline protest

Impacts of industrialization and globalization

Industrialization, the large scale growth of industry, has had profound impacts on natural resource exploitation. As societies undergo industrialization, there is an increased demand for raw materials to fuel manufacturing, construction, and energy production. As outlined by Farhan Ahmed, professor of economics and finance, industrialization can bring a myriad of challenges for natural resources. In his piece “The environmental impact of industrialization and foreign direct investment: empirical evidence from Asia-Pacific region” Ahmed writes “In addition to the many benefits of foreign direct investment and industrialization that have affected economic growth, both have significant potential for environmental degradation because most of their activities are related to the production and exploitation of natural resources." This demand often leads to intensified extraction activities, such as mining, logging, and drilling, which can result in extensive habitat destruction, deforestation, and ecosystem degradation. Additionally, industrial processes often generate pollution and waste, further exacerbating environmental impacts and threatening ecosystems and biodiversity. industrialization has been associated with the commodification of natural resources, where resources are valued primarily for their economic potential rather than their intrinsic ecological or cultural value. This commodification mindset often leads to unsustainable exploitation practices, as resources are overexploited for short-term economic gain without consideration for long-term environmental sustainability.

Globalization has significantly impacted resource exploitation by reshaping patterns of production, consumption, and trade on a global scale. The interconnectedness of economies and the proliferation of multinational corporations have led to increased competition for access to natural resources, such as minerals, fossil fuels, timber, and agricultural products, in diverse regions around the world. This heightened demand for resources has driven intensified extraction activities, often in environmentally sensitive areas, and has contributed to the overexploitation and depletion of finite resources. Haiying Liu, professor of economics, explains how globalization results in more environmental stress in her piece “Impact of governance and globalization on natural resources volatility”. In this piece she writes, “In addition to natural resources exported from the region, the technical capability required to explore natural resources is also dependent on economic globalization. Environmental pressure increases as a result of globalization.” Globalization has spurred the development of complex supply chains and trade networks that connect resource-rich regions with centers of production and consumption across the globe. While this interconnectedness has fueled economic growth and development in some regions, it has also led to the commodification and commercialization of natural resources, where resources are valued primarily for their economic potential rather than their intrinsic ecological or cultural value. Globalization has contributed to the unequal distribution of benefits and burdens associated with resource exploitation, with marginalized communities often bearing the environmental and social costs of resource extraction while multinational corporations and rich nations reap the profits

Effects on local communities

Papua New Guinea

Human Resources Macon, Georgia, 1909

When a mining company enters a developing country in the global south to extract raw materials, advocating the advantages of the industry's presence and minimizing the potential negative effects gain the cooperation of the local people. Advantageous factors are primarily in economic development establishments, such as health centers, police departments, and schools, that the government may not provide. However, these advantages are not always distributed evenly among local populations, and the income generated from extracting natural resources can result in internal conflict within the developing country. In addition to unequal distribution, the adaption of consumerist values also results in conflict over resources within local communities.

Despite being rich in natural resources, the Democratic Republic of Congo is one country in the global south suffering from the effects of the resource curse. Its valuable copper and cobalt mineral deposits make Congo vulnerable to local and international conflict over the distribution of resources. These conflicts, along with the environmental degradation effects of mining, exacerbate high poverty rates, which approximately 64% of the Congolese population live under. Natural resource extraction and climate change are intertwined in Congo, as mining for copper and cobalt creates a biodiversity loss as green covers are cleared for constructing artisanal mines and roadways. Conflict over resources, poverty, and environmental degradation leaves a large number of the Congolese population vulnerable to internal displacement, lacking resources to adapt to climate change. Beyond climate impacts, mineral mining has also been linked with adverse health impacts, such as high levels of cobalt in urine and blood samples in populations located on or near industrial mines. Mining ores pose health risks long after mining has ceased, as wastelands generate toxic metal-rich dust. The injustice perpetrated by unsafe mining ores is not exclusive to the adult and child laborers. Instead, it impacts the whole country as low wages for high-risk mining worsen poverty rates, exacerbating negative social impacts such as conflict, higher crime rates, and child mortality.

The effects of the exploitation of natural resources in the local community of a developing country are also exhibited in the impacts from the Ok Tedi Mine. After BHP entered into Papua New Guinea to exploit copper and gold, the economy of the indigenous peoples boomed. Although their quality of life has improved, initially disputes were common among the locals in terms of land rights and who should be getting the benefits from the mining project. The consequences of the Ok Tedi environmental disaster illustrate the potential negative effects from the exploitation of natural resources. The resulting mining pollution includes toxic contamination of the natural water supply for communities along the Ok Tedi River, causing widespread killing of aquatic life. When a mining company ends a project after extracting the raw materials from an area of a developing country, the local people are left to manage with the environmental damage done to their community and the long run sustainability of the economic benefits stimulated by the mining company's presence becomes a concern.

Responses and solutions

Responses and solutions to natural resource exploitation have emerged across the globe as communities and stakeholders grapple with the environmental, social, and economic impacts of unsustainable practices. These movements often employ a variety of tactics, including protests, legal challenges, boycotts, and direct actions, to challenge destructive practices and promote alternatives that prioritize environmental sustainability, social justice, and community well-being. Additionally, there has been growing recognition of the importance of indigenous knowledge, traditional ecological practices, and community-based approaches in addressing the root causes of resource exploitation and advancing sustainable development goals.

Resistance to mining in Peru

Resistance to natural resource exploitation in the developing countries is often intertwined with broader social and economic struggles. Many communities facing exploitation are marginalized and economically disadvantaged which exacerbates the unequal power dynamics at play. Resistance movements often demand not only environmental justice but also fair compensation, employment opportunities, and community development initiatives. Solidarity networks, both within countries and internationally, have been crucial in amplifying the voices of affected communities and exerting pressure on governments and corporations to adopt more sustainable and equitable practices. Despite facing significant challenges, these movements continue to inspire hope for a more just and sustainable future in the Global South and beyond.

Anti-mining protests in Peru have emerged as a significant expression of resistance against large-scale mining projects that pose environmental and social threats to local communities. One notable instance is the resistance against the Conga mining project in the Cajamarca region. José Manuyama Ahuit, a native Peruvian activist working against local mining, was quoted saying, “The river forms part of our spirit and culture. If the river dies, so does our human dignity, now this river is doomed. The colour of the water is changing, and the same devastation in other mining areas is beginning to be reproduced here in the Nanay. Local communities, including farmers and indigenous groups, have vehemently opposed the project due to concerns of water contamination and depletion. The proposed mining operation, led by multinational corporations, has been met with widespread demonstrations, blockades, and legal challenges. These protests underscore broader issues of environmental protection and indigenous rights, as communities seek to safeguard their lands and livelihoods from the detrimental impacts of resource extraction.

In response to the anti-mining protests, Peruvian authorities have often deployed security forces to quell dissent, leading to clashes and instances of violence. These clashes have resulted in injuries and fatalities on both sides, escalating tensions between mining companies, local communities, and the government. Efforts to find a peaceful resolution to the conflict have been disrupted by deep-seated mistrust and differing interests among the stakeholders involved.

Resistance in Native American communities

Resistance to natural resource exploitation in native communities has been a recurring theme throughout history, as indigenous people  have sought to protect their lands, cultures, and ways of life from the adverse impacts of extractive industries. In many cases, indigenous resistance movements have emerged as powerful forces advocating for environmental justice, indigenous rights, and sovereignty over ancestral territories. These movements often mobilize around issues such as land rights, resource extraction, and environmental protection, employing a variety of tactics, including protests, legal challenges, direct actions, and advocacy campaigns to assert indigenous control over natural resources and resist exploitative practices.

The Dakota Access Pipeline resistance, also known as the Standing Rock movement, emerged as a significant indigenous-led protest against the construction of the Dakota Access Pipeline in the United States. The pipeline, proposed by Energy Transfer Partners, was intended to transport crude oil from North Dakota to Illinois, traversing ancestral lands and sacred sites of the Standing Rock Sioux Tribe, as well as posing potential threats to water sources, including the Missouri River, which serves as a vital water supply for the tribe and millions of others downstream. The resistance movement, which began in 2016, brought together indigenous activists, environmentalists, and allies from across the country and around the world in a unified effort to oppose the pipeline's construction. Nick Estes, a scholar of American Indian studies who has followed the Dakota Access Pipeline protests closely, points out that the tactics being used in protest of the Dakota Access Pipeline have been used for generations. In his piece  “Our History is The Future”  he writes, “Our history and long traditions of Indigenous resistance provide possibilities for futures premised on justice. After all, Indigenous resistance is animated by our ancestors' refusal to be forgotten, and it is our resolute refusal to forget our ancestors and our history that animates our visions for liberation.

The Dakota Access Pipeline resistance garnered widespread attention and support, drawing thousands of people to the Standing Rock Indian Reservation in North Dakota to stand in solidarity with the Standing Rock Sioux Tribe and protect their lands and water. Among the supporters was activist and performing artists Dallas Goldtooth of the Dakota tribe. Goldtooth highlighted the importance of social media in modern protests saying, “social media allowed immediate direct one-on-one access and kind of this perception of unfiltered access – unfiltered access to what was happening on the ground"

The movement was characterized by nonviolent protests, prayer ceremonies, and acts of civil disobedience, as well as legal challenges aimed at halting the pipeline's construction and holding the government and energy companies accountable for violating indigenous rights and environmental regulations. The resistance movement also sparked a broader conversation about indigenous sovereignty, environmental justice, and the impacts of fossil fuel infrastructure on indigenous communities and the environment.

Prenatal development

From Wikipedia, the free encyclopedia
Human embryo at 7-8 weeks from conception.

Prenatal development (from Latin natalis 'relating to birth') involves the development of the embryo and of the fetus during a viviparous animal's gestation. Prenatal development starts with fertilization, in the germinal stage of embryonic development, and continues in fetal development until birth. The term "prenate" is used to describe an unborn offspring at any stage of gestation.

In human pregnancy, prenatal development is also called antenatal development. The development of the human embryo follows fertilization, and continues as fetal development. By the end of the tenth week of gestational age, the embryo has acquired its basic form and is referred to as a fetus. The next period is that of fetal development where many organs become fully developed. This fetal period is described both topically (by organ) and chronologically (by time) with major occurrences being listed by gestational age.

The very early stages of embryonic development are the same in all mammals, but later stages of development, and the length of gestation varies.

Terminology

In the human:

Stages during pregnancy. Embryonic development is marked in green. Weeks and months are numbered by gestation.

Different terms are used to describe prenatal development, meaning development before birth. A term with the same meaning is the "antepartum" (from Latin ante "before" and parere "to give birth") Sometimes "antepartum" is however used to denote the period between the 24th/26th week of gestational age until birth, for example in antepartum hemorrhage.

The perinatal period (from Greek peri, "about, around" and Latin nasci "to be born") is "around the time of birth". In developed countries and at facilities where expert neonatal care is available, it is considered from 22 completed weeks (usually about 154 days) of gestation (the time when birth weight is normally 500 g) to 7 completed days after birth. In many of the developing countries the starting point of this period is considered 28 completed weeks of gestation (or weight more than 1000 g).

Fertilization

A sperm cell fertilizing an egg cell

Fertilization marks the first germinal stage of embryonic development. When semen is released into the vagina, the spermatozoa travel through the cervix, along the body of the uterus, and into one of the fallopian tubes where fertilization usually takes place in the ampulla. A great many sperm cells are released with the possibility of just one managing to adhere to and enter the thick protective layer surrounding the egg cell (ovum). The first sperm cell to successfully penetrate the egg cell donates its genetic material (DNA) to combine with the DNA of the egg cell resulting in a new one-celled zygote. The term "conception" refers variably to either fertilization or to formation of the conceptus after its implantation in the uterus, and this terminology is controversial.

The zygote will develop into a male if the egg is fertilized by a sperm that carries a Y chromosome, or a female if the sperm carries an X chromosome. The Y chromosome contains a gene, SRY, which will switch on androgen production at a later stage leading to the development of a male body type. In contrast, the mitochondrial DNA of the zygote comes entirely from the egg cell.

Development of the embryo

The initial stages of human embryogenesis

Following fertilization, the embryonic stage of development continues until the end of the 10th week (gestational age) (8th week fertilization age). The first two weeks from fertilization is also referred to as the germinal stage or preembryonic stage.

The zygote spends the next few days traveling down the fallopian tube dividing several times to form a ball of cells called a morula. Further cellular division is accompanied by the formation of a small cavity between the cells. This stage is called a blastocyst. Up to this point there is no growth in the overall size of the embryo, as it is confined within a glycoprotein shell, known as the zona pellucida. Instead, each division produces successively smaller cells.

The blastocyst reaches the uterus at roughly the fifth day after fertilization. The blastocyst hatches from the zona pellucida allowing the blastocyst's outer cell layer of trophoblasts to come into contact with, and adhere to, the endometrial cells of the uterus. The trophoblasts will eventually give rise to extra-embryonic structures, such as the placenta and the membranes. The embryo becomes embedded in the endometrium in a process called implantation. In most successful pregnancies, the embryo implants 8 to 10 days after ovulation. The embryo, the extra-embryonic membranes, and the placenta are collectively referred to as a conceptus, or the "products of conception".

Rapid growth occurs and the embryo's main features begin to take form. This process is called differentiation, which produces the varied cell types (such as blood cells, kidney cells, and nerve cells). A spontaneous abortion, or miscarriage, in the first trimester of pregnancy is usually due to major genetic mistakes or abnormalities in the developing embryo. During this critical period the developing embryo is also susceptible to toxic exposures, such as:

Nutrition

The embryo passes through 3 phases of acquisition of nutrition from the mother:

  1. Absorption phase: Zygote is nourished by cellular cytoplasm and secretions in fallopian tubes and uterine cavity.
  2. Histoplasmic transfer: After nidation and before establishment of uteroplacental circulation, embryonic nutrition is derived from decidual cells and maternal blood pools that open up as a result of eroding activity of trophoblasts.
  3. Hematotrophic phase: After third week of gestation, substances are transported passively via intervillous space.

Development of the fetus

The first ten weeks of gestational age is the period of embryogenesis and together with the first three weeks of prenatal development make up the first trimester of pregnancy.

From the 10th week of gestation (8th week of development), the developing embryo is called a fetus. All major structures are formed by this time, but they continue to grow and develop. Because the precursors of the organs are now formed, the fetus is not as sensitive to damage from environmental exposure as the embryo was. Instead, toxic exposure often causes physiological abnormalities or minor congenital malformation.

Development of organ systems

Development continues throughout the life of the fetus and through into life after birth. Significant changes occur to many systems in the period after birth as they adapt to life outside the uterus.

Fetal blood

Hematopoiesis first takes place in the yolk sac. The function is transferred to the liver by the 10th week of gestation and to the spleen and bone marrow beyond that. The total blood volume is about 125 ml/kg of fetal body weight near term.

Red blood cells

Megaloblastic red blood cells are produced early in development, which become normoblastic near term. Life span of prenatal RBCs is 80 days. Rh antigen appears at about 40 days of gestation.

White blood cells

The fetus starts producing leukocytes at 2 months gestational age, mainly from the thymus and the spleen. Lymphocytes derived from the thymus are called T lymphocytes (T cells), whereas those derived from bone marrow are called B lymphocytes (B cells). Both of these populations of lymphocytes have short-lived and long-lived groups. Short-lived T cells usually reside in thymus, bone marrow and spleen; whereas long-lived T cells reside in the blood stream. Plasma cells are derived from B cells and their life in fetal blood is 0.5 to 2 days.

Glands

The thyroid is the first gland to develop in the embryo at the 4th week of gestation. Insulin secretion in the fetus starts around the 12th week of gestation.

Cognitive development

Electrical brain activity is first detected at the end of week 5 of gestation. Synapses do not begin to form until week 17. Neural connections between the sensory cortex and thalamus develop as early as 24 weeks' gestational age, but the first evidence of their function does not occur until around 30 weeks, when minimal consciousness, dreaming, and the ability to feel pain emerges.

Initial knowledge of the effects of prenatal experience on later neuropsychological development originates from the Dutch Famine Study, which researched the cognitive development of individuals born after the Dutch famine of 1944–45. The first studies focused on the consequences of the famine to cognitive development, including the prevalence of intellectual disability. Such studies predate David Barker's hypothesis about the association between the prenatal environment and the development of chronic conditions later in life. The initial studies found no association between malnourishment and cognitive development, but later studies found associations between malnourishment and increased risk for schizophrenia, antisocial disorders, and affective disorders.

There is evidence that the acquisition of language begins in the prenatal stage. After 26 weeks of gestation, the peripheral auditory system is already fully formed. Also, most low-frequency sounds (less than 300 Hz) can reach the fetal inner ear in the womb of mammals. Those low-frequency sounds include pitch, rhythm, and phonetic information related to language. Studies have indicated that fetuses react to and recognize differences between sounds. Such ideas are further reinforced by the fact that newborns present a preference for their mother's voice, present behavioral recognition of stories only heard during gestation, and (in monolingual mothers) present preference for their native language. A more recent study with EEG demonstrated different brain activation in newborns hearing their native language compared to when they were presented with a different language, further supporting the idea that language learning starts while in gestation.

Growth rate

The growth rate of a fetus is linear up to 37 weeks of gestation, after which it plateaus. The growth rate of an embryo and infant can be reflected as the weight per gestational age, and is often given as the weight put in relation to what would be expected by the gestational age. A baby born within the normal range of weight for that gestational age is known as appropriate for gestational age (AGA). An abnormally slow growth rate results in the infant being small for gestational age, while an abnormally large growth rate results in the infant being large for gestational age. A slow growth rate and preterm birth are the two factors that can cause a low birth weight. Low birth weight (below 2000 grams) can slightly increase the likelihood of schizophrenia.

The growth rate can be roughly correlated with the fundal height of the uterus which can be estimated by abdominal palpation. More exact measurements can be performed with obstetric ultrasonography.

Factors influencing development

Intrauterine growth restriction is one of the causes of low birth weight associated with over half of neonatal deaths.

Poverty

Poverty has been linked to poor prenatal care and has been an influence on prenatal development. Women in poverty are more likely to have children at a younger age, which results in low birth weight. Many of these expecting mothers have little education and are therefore less aware of the risks of smoking, drinking alcohol, and drug use – other factors that influence the growth rate of a fetus.

Mother's age

The term Advanced maternal age is used to describe women who are over 35 during pregnancy. Women who give birth over the age of 35 are more likely to experience complications ranging from preterm birth and delivery by Caesarean section, to an increased risk of giving birth to a child with chromosomal abnormalities such as Down syndrome. The chances of stillbirth and miscarriage also increase with maternal age as do the chances of the mother suffering from Gestational diabetes or high blood pressure during pregnancy. Some sources suggest that health problems are also associated with teenage pregnancy. These may include high blood pressure, low birth weight and premature birth. Some studies note that adolescent pregnancy is often associated with poverty, low education, and inadequate family support. Stigma and social context tend to create and exacerbate some of the challenges of adolescent pregnancy.

Drug use

An estimated 5 percent of fetuses in the United States are exposed to illicit drug use during pregnancy. Maternal drug use occurs when drugs ingested by the pregnant woman are metabolized in the placenta and then transmitted to the fetus. Recent research displays that there is a correlation between fine motor skills and prenatal risk factors such as the use of psychoactive substances and signs of abortion during pregnancy. As well as perinatal risk factors such as gestation time, duration of delivery, birth weight and postnatal risk factors such as constant falls.

Cannabis

When using cannabis, there is a greater risk of birth defects, low birth weight, and a higher rate of death in infants or stillbirths. Drug use will influence extreme irritability, crying, and risk for SIDS once the fetus is born. Marijuana will slow the fetal growth rate and can result in premature delivery. It can also lead to low birth weight, a shortened gestational period and complications in delivery. Cannabis use during pregnancy was unrelated to risk of perinatal death or need for special care, but, the babies of women who used cannabis at least once per week before and throughout pregnancy were 216g lighter than those of non‐users, had significantly shorter birth lengths and smaller head circumferences.

Opioids

Opioids including heroin will cause interrupted fetal development, stillbirths, and can lead to numerous birth defects. Heroin can also result in premature delivery, creates a higher risk of miscarriages, result in facial abnormalities and head size, and create gastrointestinal abnormalities in the fetus. There is an increased risk for SIDS, dysfunction in the central nervous system, and neurological dysfunctions including tremors, sleep problems, and seizures. The fetus is also put at a great risk for low birth weight and respiratory problems.

Cocaine

Cocaine use results in a smaller brain, which results in learning disabilities for the fetus. Cocaine puts the fetus at a higher risk of being stillborn or premature. Cocaine use also results in low birthweight, damage to the central nervous system, and motor dysfunction. The vasoconstriction of the effects of cocaine lead to a decrease in placental blood flow to the fetus that results in fetal hypoxia (oxygen deficiency) and decreased fetal nutrition; these vasoconstrictive effects on the placenta have been linked to the number of complications in malformations that are evident in the newborn.

Methamphetamine

Prenatal methamphetamine exposure has shown to negatively impact brain development and behavioral functioning. A 2019 study further investigated neurocognitive and neurodevelopmental effects of prenatal methamphetamine exposure. This study had two groups, one containing children who were prenatally exposed to methamphetamine but no other illicit drugs and one containing children who met diagnosis criteria for ADHD but were not prenatally exposed to any illicit substance. Both groups of children completed intelligence measures to compute an IQ. Study results showed that the prenatally exposed children performed lower on the intelligence measures than their non-exposed peers with ADHD. The study results also suggest that prenatal exposure to methamphetamine may negatively impact processing speed as children develop.

Alcohol

Maternal alcohol use leads to disruptions of the fetus' brain development, interferes with the fetus' cell development and organization, and affects the maturation of the central nervous system. Even small amounts of alcohol use can cause lower height, weight and head size at birth and higher aggressiveness and lower intelligence during childhood. Fetal alcohol spectrum disorder is a developmental disorder that is a consequence of heavy alcohol intake by the mother during pregnancy. Children with FASD have a variety of distinctive facial features, heart problems, and cognitive problems such as developmental disabilities, attention difficulties, and memory deficits.

Tobacco use

Tobacco smoking during pregnancy exposes the fetus to nicotine, tar, and carbon monoxide. Nicotine results in less blood flow to the fetus because it constricts the blood vessels. Carbon monoxide reduces the oxygen flow to the fetus. The reduction of blood and oxygen flow may result in miscarriage, stillbirth, low birth weight, and premature births. Exposure to secondhand smoke leads to higher risks of low birth weight and childhood cancer.

Infections

If a mother is infected with a disease, the placenta cannot always filter out the pathogens. Viruses such as rubella, chicken pox, mumps, herpes, and human immunodeficiency virus (HIV) are associated with an increased risk of miscarriage, low birth weight, prematurity, physical malformations, and intellectual disabilities. HIV can lead to acquired immune deficiency syndrome (AIDS). Untreated HIV carries a risk of between 10 and 20 per cent of being passed on to the fetus. Bacterial or parasitic diseases may also be passed on to the fetus, and include chlamydia, syphilis, tuberculosis, malaria, and commonly toxoplasmosis. Toxoplasmosis can be acquired through eating infected undercooked meat or contaminated food, and by drinking contaminated water. The risk of fetal infection is lowest during early pregnancy, and highest during the third trimester. However, in early pregnancy the outcome is worse, and can be fatal.

Maternal nutrition

Adequate nutrition is needed for a healthy fetus. Mothers who gain less than 20 pounds during pregnancy are at increased risk for having a preterm or low birth weight infant. Iron and iodine are especially important during prenatal development. Mothers who are deficient in iron are at risk for having a preterm or low birth weight infant. Iodine deficiencies increase the risk of miscarriage, stillbirth, and fetal brain abnormalities. Adequate prenatal care gives an improved result in the newborn.

Low birth weight

Low birth weight increases an infants risk of long-term growth and cognitive and language deficits. It also results in a shortened gestational period and can lead to prenatal complications.

Stress

Stress during pregnancy can have an impact the development of the embryo. Reilly (2017) states that stress can come from many forms of life events such as community, family, financial issues, and natural causes. While a woman is pregnant, stress from outside sources can take a toll on the growth in the womb that may affect the child's learning and relationships when born. For instance, they may have behavioral problems and might be antisocial. The stress that the mother experiences affects the fetus and the fetus' growth which can include the fetus' nervous system (Reilly, 2017). Stress can also lead to low birth weight. Even after avoiding other factors like alcohol, drugs, and being healthy, stress can have its impacts whether families know it or not. Many women who deal with maternal stress do not seek treatment. Similar to stress, Reilly stated that in recent studies, researchers have found that pregnant women who show depressive symptoms are not as attached and bonded to their child while it is in the womb (2017).

Environmental toxins

Exposure to environmental toxins in pregnancy lead to higher rates of miscarriage, sterility, and birth defects. Toxins include fetal exposure to lead, mercury, and ethanol or hazardous environments. Prenatal exposure to mercury may lead to physical deformation, difficulty in chewing and swallowing, and poor motoric coordination. Exposure to high levels of lead prenatally is related to prematurity, low birth weight, brain damage, and a variety of physical defects. Exposure to persistent air pollution from traffic and smog may lead to reduced infant head size, low birth weight, increased infant death rates, impaired lung and immune system development.

Probabilistic numerics

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