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In philosophy, rationalism is the epistemological view that "regards reason as the chief source and test of knowledge" or "any view appealing to reason as a source of knowledge or justification". More formally, rationalism is defined as a methodology or a theory "in which the criterion of the truth is not sensory but intellectual and deductive".

In an old controversy, rationalism was opposed to empiricism, where the rationalists believed that reality has an intrinsically logical structure. Because of this, the rationalists argued that certain truths exist and that the intellect can directly grasp these truths. That is to say, rationalists asserted that certain rational principles exist in logic, mathematics, ethics, and metaphysics that are so fundamentally true that denying them causes one to fall into contradiction. The rationalists had such a high confidence in reason that empirical proof and physical evidence were regarded as unnecessary to ascertain certain truths – in other words, "there are significant ways in which our concepts and knowledge are gained independently of sense experience".

Different degrees of emphasis on this method or theory lead to a range of rationalist standpoints, from the moderate position "that reason has precedence over other ways of acquiring knowledge" to the more extreme position that reason is "the unique path to knowledge". Given a pre-modern understanding of reason, rationalism is identical to philosophy, the Socratic life of inquiry, or the zetetic (skeptical) clear interpretation of authority (open to the underlying or essential cause of things as they appear to our sense of certainty). In recent decades, Leo Strauss sought to revive "Classical Political Rationalism" as a discipline that understands the task of reasoning, not as foundational, but as maieutic.

In the 17th-century Dutch Republic, the rise of early modern rationalism – as a highly systematic school of philosophy in its own right for the first time in history – exerted an immense and profound influence on modern Western thought in general, with the birth of two influential rationalistic philosophical systems of Descartes (who spent most of his adult life and wrote all his major work in the United Provinces of the Netherlands) and Spinoza–namely Cartesianism and Spinozism. It was the 17th-century arch-rationalists like Descartes, Spinoza and Leibniz who have given the "Age of Reason" its name and place in history.

In politics, rationalism, since the Enlightenment, historically emphasized a "politics of reason" centered upon rational choice, utilitarianism, secularism, and irreligion – the latter aspect's antitheism was later softened by the adoption of pluralistic reasoning methods practicable regardless of religious or irreligious ideology. In this regard, the philosopher John Cottingham noted how rationalism, a methodology, became socially conflated with atheism, a worldview:

In the past, particularly in the 17th and 18th centuries, the term 'rationalist' was often used to refer to free thinkers of an anti-clerical and anti-religious outlook, and for a time the word acquired a distinctly pejorative force (thus in 1670 Sanderson spoke disparagingly of 'a mere rationalist, that is to say in plain English an atheist of the late edition...'). The use of the label 'rationalist' to characterize a world outlook which has no place for the supernatural is becoming less popular today; terms like 'humanist' or 'materialist' seem largely to have taken its place. But the old usage still survives.

Philosophical usage