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Technology transfer, also called transfer of technology (TOT), is the process of transferring (disseminating) technology from the person or organization that owns or holds it to another person or organization. It occurs along various axes: among universities, from universities to businesses (and vice versa), from large businesses to smaller ones (and vice versa), from governments to businesses (and vice versa), across geopolitical borders, both formally and informally, and both openly and surreptitiously. Often it occurs by concerted effort to share skills, knowledge, technologies, methods of manufacturing, samples of manufacturing, and facilities among governments or universities and other institutions to ensure that scientific and technological developments are accessible to a wider range of users who can then further develop and exploit the technology into new products, processes, applications, materials, or services. It is closely related to (and may arguably be considered a subset of) knowledge transfer. Horizontal transfer is the movement of technologies from one area to another. At present transfer of technology (TOT) is primarily horizontal. Vertical transfer occurs when technologies are moved from applied research centers to research and development departments.

Technology transfer is promoted at conferences organized by such groups as the Ewing Marion Kauffman Foundation and the Association of University Technology Managers, and at "challenge" competitions by organizations such as the Center for Advancing Innovation in Maryland. Local venture capital organizations such as the Mid-Atlantic Venture Association (MAVA) also sponsor conferences at which investors assess the potential for commercialization of technology.

Technology brokers are people who discovered how to bridge the emergent worlds and apply scientific concepts or processes to new situations or circumstances. A related term, used almost synonymously, especially in Europe, is "technology valorisation". While conceptually the practice has been utilized for many years (in ancient times, Archimedes was notable for applying science to practical problems), the present-day volume of research, combined with high-profile failures at Xerox PARC and elsewhere, has led to a focus on the process itself.

Whereas technology transfer can involve the dissemination of highly complex technology from capital-intensive origins to low-capital recipients (and can involve aspects of dependency and fragility of systems), it also can involve appropriate technology, not necessarily high-tech or expensive, that is better disseminated, yielding robustness and independence of systems.

Transfer process