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The law of truly large numbers (a statistical adage), attributed to Persi Diaconis and Frederick Mosteller, states that with a large enough number of samples, any outrageous (i.e. unlikely in any single sample) thing is likely to be observed. Because we never find it notable when likely events occur, we highlight unlikely events and notice them more. The law is often used to falsify different pseudo-scientific claims, as such it and its use are sometimes criticized by fringe scientists.

The law is meant to make a statement about probabilities and statistical significance: in large enough masses of statistical data, even minuscule fluctuations attain statistical significance. Thus in truly large numbers of observations, it is paradoxically easy to find significant correlations, in large numbers, which still do not lead to causal theories (see: spurious correlation), and which by their collective number, might lead to obfuscation as well.

The law can be rephrased as "large numbers also deceive", something which is counter-intuitive to a descriptive statistician. More concretely, skeptic Penn Jillette has said, "Million-to-one odds happen eight times a day in New York" (population about 8,000,000).

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