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Responsible drug use maximizes the benefits and reduces the risk of negative impact on the lives of the user. For illegal psychoactive drugs that are not diverted prescription controlled substances, some critics believe that illegal recreational use is inherently irresponsible, due to the unpredictable and unmonitored strength and purity of the drugs and the risks of addiction, infection, and other side effects.
 
Nevertheless, harm-reduction advocates claim that the user can be responsible by employing the same general principles applicable to the use of alcohol: avoiding hazardous situations, excessive doses, and hazardous combinations of drugs; avoiding injection; and not using drugs at the same time as activities that may be unsafe without a sober state. Drug use can be thought of as an activity that can be simultaneously beneficial but risky, similar to driving a car, skiing, skydiving, surfing, or mountain climbing, the risks of which can be minimized by using caution and common sense. These advocates also point out that government action (or inaction) makes responsible drug use more difficult, such as by making drugs of known purity and strength unavailable.

Principles