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19th century German philosopher Karl Marx, the founder and primary theorist of Marxism viewed religion as "the soul of soulless conditions" or the "opium of the people". At the same time, Marx saw religion as a form of protest by the working classes against their poor economic conditions and their alienation. In the Marxist–Leninist interpretation, all modern religions and churches are considered as "organs of bourgeois reaction" used for "the exploitation and the stupefaction of the working class". Due to this, a number of Marxist–Leninist governments in the 20th century, such as the Soviet Union after Vladimir Lenin and the People's Republic of China under Mao Zedong, implemented rules introducing state atheism.

Marxist political theorists and revolutionaries on religion