A Medley of Potpourri

Monday, February 10, 2025

Genocide Convention

From Wikipedia, the free encyclopedia
https://en.wikipedia.org/wiki/Genocide_Convention

Genocide Convention
Convention on the Prevention and Punishment of the Crime of Genocide
Signed	9 December 1948
Location	Palais de Chaillot, Paris, France
Effective	12 January 1951
Signatories	39
Parties	153
Depositary	Secretary-General of the United Nations

The Convention on the Prevention and Punishment of the Crime of Genocide (CPPCG), or the Genocide Convention, is an international treaty that criminalizes genocide and obligates state parties to pursue the enforcement of its prohibition. It was the first legal instrument to codify genocide as a crime, and the first human rights treaty unanimously adopted by the United Nations General Assembly, on 9 December 1948, during the third session of the United Nations General Assembly. The Convention entered into force on 12 January 1951 and has 153 state parties as of June 2024.

The Genocide Convention was conceived largely in response to World War II, which saw atrocities such as the Holocaust that lacked an adequate description or legal definition. Polish-Jewish lawyer Raphael Lemkin, who had coined the term genocide in 1944 to describe Nazi policies in occupied Europe and the Armenian genocide, campaigned for its recognition as a crime under international law. Lemkin also linked colonialism with genocide, mentioning colonial genocides outside of Europe in his writings. In a 1946 resolution, the General Assembly recognized genocide as an international crime and called for the creation of a binding treaty to prevent and punish its perpetration. Subsequent discussions and negotiations among UN member states resulted in the CPPCG.

The Convention defines genocide as any of five "acts committed with intent to destroy, in whole or in part, a national, ethnic, racial or religious group." These five acts include killing members of the group, causing them serious bodily or mental harm, imposing living conditions intended to destroy the group, preventing births, and forcibly transferring children out of the group. Victims are targeted because of their real or perceived membership of a group, not randomly. The convention further criminalizes "complicity, attempt, or incitement of its commission." Member states are prohibited from engaging in genocide and obligated to pursue the enforcement of this prohibition. All perpetrators are to be tried regardless of whether they are private individuals, public officials, or political leaders with sovereign immunity.

The CPPCG has influenced law at both the national and international level. Its definition of genocide has been adopted by international and hybrid tribunals, such as the International Criminal Court, and incorporated into the domestic law of several countries. Its provisions are widely considered to be reflective of customary law and therefore binding on all nations whether or not they are parties. The International Court of Justice (ICJ) has likewise ruled that the principles underlying the Convention represent a peremptory norm against genocide that no government can derogate. The Genocide Convention authorizes the mandatory jurisdiction of the ICJ to adjudicate disputes, leading to international litigation such as the Rohingya genocide case and dispute over the 2022 Russian invasion of Ukraine.

Definition of genocide

Article 2 of the Convention defines genocide as:

... any of the following acts committed with intent to destroy, in whole or in part, a national, ethnical, racial or religious group, as such:
(a) Killing members of the group;
(b) Causing serious bodily or mental harm to members of the group;
(c) Deliberately inflicting on the group conditions of life calculated to bring about its physical destruction in whole or in part;
(d) Imposing measures intended to prevent births within the group;
(e) Forcibly transferring children of the group to another group.
— Convention on the Prevention and Punishment of the Crime of Genocide, Article 2

Article 3 defines the crimes that can be punished under the convention:

(a) Genocide;
(b) Conspiracy to commit genocide;
(c) Direct and public incitement to commit genocide;
(d) Attempt to commit genocide;
(e) Complicity in genocide.
— Convention on the Prevention and Punishment of the Crime of Genocide, Article 3

The convention was passed to outlaw actions similar to the Armenian genocide and the Holocaust.

The first draft of the Convention included political killing, but the USSR along with some other nations would not accept that actions against groups identified as holding similar political opinions or social status would constitute genocide, so these stipulations were subsequently removed in a political and diplomatic compromise.

Early drafts also included acts of cultural destruction in the concept of genocide, but these were opposed by former European colonial powers and some settler countries. Such acts, which Lemkin saw as part and parcel of the concept of genocide, have since often been discussed as cultural genocide (a term also not enshrined in international law). In June 2021, the International Criminal Court issued new guidelines for how cultural destruction, when occurring alongside other recognized acts of genocide, can potentially be corroborating evidence for the intent of the crime of genocide.

The Genocide Convention establishes five prohibited acts that, when committed with the requisite intent, amount to genocide. Genocide is not just defined as wide scale massacre-style killings that are visible and well-documented. International law recognizes a broad range of forms of violence in which the crime of genocide can be enacted.

Killing members of the group Article II(a)

While mass killing is not necessary for genocide to have been committed, it has been present in almost all recognized genocides. In certain instances, men and adolescent boys are singled out for murder in the early stages, such as in the genocide of the Yazidis by Daesh, the Ottoman Turks' attack on the Armenians, and the Burmese security forces' attacks on the Rohingya. Men and boys are typically subject to "fast" killings, such as by gunshot. Women and girls are more likely to die slower deaths by slashing, burning, or as a result of sexual violence. The jurisprudence of the International Criminal Tribunal for Rwanda (ICTR), among others, shows that both the initial executions and those that quickly follow other acts of extreme violence, such as rape and torture, are recognized as falling under the first prohibited act.

A less settled discussion is whether deaths that are further removed from the initial acts of violence can be addressed under this provision of the Genocide Convention. Legal scholars have posited, for example, that deaths resulting from other genocidal acts including causing serious bodily or mental harm or the successful deliberate infliction of conditions of life calculated to bring about physical destruction should be considered genocidal killings.

Causing serious bodily or mental harm to members of the group Article II(b)

This second prohibited act can encompass a wide range of non-fatal genocidal acts. The ICTR and International Criminal Tribunal for the former Yugoslavia (ICTY) have held that rape and sexual violence may constitute the second prohibited act of genocide by causing both physical and mental harm. In its landmark Akayesu decision, the ICTR held that rapes and sexual violence resulted in "physical and psychological destruction". Sexual violence is a hallmark of genocidal violence, with most genocidal campaigns explicitly or implicitly sanctioning it. It is estimated that 250,000 to 500,000 women were raped in the three months of the Rwandan genocide, many of whom were subjected to multiple rapes or gang rape. In Darfur, a systemic campaign of rape and often sexual mutilation was carried out and in Burma public mass rapes and gang rapes were inflicted on the Rohingya by Burmese security forces. Sexual slavery was documented in the Armenian genocide by the Ottoman Turks and Daesh's genocide of the Yazidi.

Torture and other cruel, inhuman, or degrading treatment or punishment, when committed with the requisite intent, are also genocide by causing serious bodily or mental harm to members of the group. The ICTY found that both experiencing a failed execution and watching the murder of one's family members may constitute torture. The Syrian Commission of Inquiry (COI) also found that enslavement, removal of one's children into indoctrination or sexual slavery, and acts of physical and sexual violence rise to the level of torture, as well. While it was subject to some debate, the ICTY and, later, the Syrian COI held that under some circumstances deportation and forcible transfer may also cause serious bodily or mental harm.

Deliberately inflicting on the group conditions of life calculated to bring about its physical destruction Article II(c)

The third prohibited act is distinguished from the genocidal act of killing because the deaths are not immediate (or may not even come to pass), but rather create circumstances that do not support prolonged life. Due to the longer period of time before the actual destruction would be achieved, the ICTR held that courts must consider the duration of time the conditions are imposed as an element of the act. In the 19th century the United States federal government supported the extermination of bison, which Native Americans in the Great Plains relied on as a source of food. This was done for various reasons, primarily to pressure them onto reservations during times of conflict. Some genocide experts describe this as an example of genocide that involves removing the means of survival.

The ICTR provided guidance into what constitutes a violation of the third act. In Akayesu, it identified "subjecting a group of people to a subsistence diet, systematic expulsion from homes and the reduction of essential medical services below minimum requirement" as rising to genocide. In Kayishema and Ruzindana, it extended the list to include: "lack of proper housing, clothing, hygiene and medical care or excessive work or physical exertion" among the conditions. It further noted that, in addition to deprivation of necessary resources, rape could also fit within this prohibited act. In August 2023, founding chief prosecutor of the International Criminal Court (ICC) Luis Moreno Ocampo published a report presenting evidence that Azerbaijan was committing genocide against the ethnic Armenians of Artsakh Nagorno-Karabakh under Article II(c) of the Genocide Convention by placing their historic land under a comprehensive blockade, cutting all access to food, medical supplies, electricity, gas, internet, and stopping all movement of people to and from Armenia.

Imposing measures intended to prevent births within the group Article II(d)

The fourth prohibited act is aimed at preventing the protected group from regenerating through reproduction. It encompasses acts affecting reproduction and intimate relationships, such as involuntary sterilization, forced abortion, the prohibition of marriage, and long-term separation of men and women intended to prevent procreation. Rape has been found to violate the fourth prohibited act on two bases: where the rape was committed with the intent to impregnate a woman and thereby force her to carry a child of another group (in societies where group identity is determined by patrilineal identity) and where the person raped subsequently refuses to procreate as a result of the trauma. Accordingly, it can take into account both physical and mental measures imposed by the perpetrators.

Forcibly transferring children of the group to another group Article II(e)

The final prohibited act is the only prohibited act that does not lead to physical or biological destruction, but rather to destruction of the group as a cultural and social unit. It occurs when children of the protected group are transferred to the perpetrator group. Boys are typically taken into the group by changing their names to those common of the perpetrator group, converting their religion, and using them for labor or as soldiers. Girls who are transferred are not generally converted to the perpetrator group, but instead treated as chattel, as played out in both the Yazidi and Armenian genocides.

Parties

As of June 2024, there are 153 state parties to the Genocide Convention—representing the vast majority of sovereign nations—with the most recent being Zambia in April 2022; one state, the Dominican Republic, has signed but not ratified the treaty. Forty-four states have neither signed nor ratified the convention.

Despite its delegates playing a key role in drafting the convention, the United States did not become a party until 1988—a full forty years after it was opened for signature—and did so only with reservations precluding punishment of the country if it were ever accused of genocide. These were due to traditional American suspicion of any international authority that could override US law. U.S. ratification of the convention was owed in large part to campaigning by Senator William Proxmire, who addressed the Senate in support of the treaty every day it was in session between 1967 and 1986.

Reservations

Immunity from prosecutions

Several parties conditioned their ratification of the Convention on reservations that grant immunity from prosecution for genocide without the consent of the national government:


Parties making reservations from prosecution	Note
Bahrain
Bangladesh
China
India
Malaysia	Opposed by Netherlands, United Kingdom
Morocco
Myanmar
Singapore	Opposed by Netherlands, United Kingdom
United Arab Emirates
United States of America	Opposed by Denmark, Estonia, Finland, Greece, Ireland, Italy, Mexico, Netherlands, Norway, Spain, Sweden, Turkey and United Kingdom
Venezuela
Vietnam	Opposed by United Kingdom
Yemen	Opposed by United Kingdom

Application to non-self-governing territories

Any Contracting Party may at any time, by notification addressed to the Secretary-General of the United Nations, extend the application of the present Convention to all or any of the territories for the conduct of whose foreign relations that Contracting Party is responsible
— Convention on the Prevention and Punishment of the Crime of Genocide, Article 12

Several countries opposed this article, considering that the convention automatically also should apply to Non-Self-Governing Territories:

Albania
Belarus
Bulgaria
Hungary
Mongolia
Myanmar
Poland
Romania
Russian Federation
Ukraine

The opposition of those countries were in turn opposed by:

Australia
Belgium
Brazil
Ecuador
China
Netherlands
Sri Lanka
United Kingdom

(However, exceptionally, Australia did make such a notification at the same time as the ratification of the convention for Australia proper, 8 July 1949, with the effect that the convention did apply also to all territories under Australian control simultaneously, as the USSR et alii had demanded. The European colonial powers in general did not then make such notifications.)

Litigation

United States

One of the first accusations of genocide submitted to the UN after the Convention entered into force concerned the treatment of Black Americans. The Civil Rights Congress drafted a 237-page petition arguing that even after 1945, the United States had been responsible for hundreds of wrongful deaths, both legal and extra-legal, as well as numerous other supposedly genocidal abuses. Leaders from the Black community and left activists William Patterson, Paul Robeson, and W. E. B. Du Bois presented this petition to the UN in December 1951. It was rejected as a misuse of the intent of the treaty. Charges under We Charge Genocide entailed the lynching of more than 10,000 African Americans with an average of more than 100 per year, with the full number being unconfirmed at the time due to unreported murder cases.

Yugoslavia

The first state and parties to be found in breach of the Genocide Convention were Serbia and Montenegro, and numerous Bosnian Serb leaders. In Bosnia and Herzegovina v. Serbia and Montenegro, the International Court of Justice presented its judgment on 26 February 2007. It cleared Serbia of direct involvement in genocide during the Bosnian war. International Tribunal findings have addressed two allegations of genocidal events, including the 1992 ethnic cleansing campaign in municipalities throughout Bosnia, as well as the convictions found in regards to the Srebrenica massacre of 1995 in which the tribunal found, "Bosnian Serb forces committed genocide, they targeted for extinction, the 40,000 Bosnian Muslims of Srebrenica ... the trial chamber refers to the crimes by their appropriate name, genocide ..." However, individual convictions applicable to the 1992 ethnic cleansings have not been secured. A number of domestic courts and legislatures have found these events to have met the criteria of genocide, and the ICTY found the acts of, and intent to destroy to have been satisfied, the "dolus specialis" still in question and before the MICT, a UN war crimes court, but ruled that Belgrade did breach international law by failing to prevent the 1995 Srebrenica genocide, and for failing to try or transfer the persons accused of genocide to the ICTY, in order to comply with its obligations under Articles I and VI of the Genocide Convention, in particular in respect of General Ratko Mladić.

Myanmar

Myanmar has been accused of genocide against its Rohingya community in Rakhine State after around 800,000 Rohingya fled at gunpoint to neighbouring Bangladesh in 2016 and 2017, while their home villages were systematically burned. The International Court of Justice has given its first circular in 2018 asking Myanmar to protect its Rohingya from genocide. Myanmar's civilian government was overthrown by the military on 1 February 2021; since the military is widely seen as the main culprit of the genocide, the coup presents a further challenge to the ICJ.

Russia

Russian accusations of genocide by Ukraine

In February 2022, Russia invaded Ukraine, claiming that it acted, among other reasons, in order to protect Russian-speaking Ukrainians from genocide. This unfounded and false Russian charge has been widely condemned, and has been called by genocide experts accusation in a mirror, a powerful, historically recurring, form of incitement to genocide.

Russian atrocities in Ukraine

Russian forces committed numerous atrocities and war crimes in Ukraine, including all five of the potentially genocidal acts listed in the Genocide Convention. Canada, Czechia, Estonia, Ireland, Latvia, Lithuania, Poland, and Ukraine have accused Russia of genocide. In April 2022 Genocide Watch issued a genocide alert for Ukraine. A May 2022 report by 35 legal and genocide experts concluded that Russia has violated the Genocide Convention by the direct and public incitement to commit genocide, and that a pattern of Russian atrocities implies the intent to destroy the Ukrainian national group, and the consequent serious risk of genocide triggers the obligation to prevent it on signatory states.

Israel

In December 2023 South Africa formally accused Israel of violating the Genocide Convention, filing the case South Africa v. Israel (Genocide Convention), due to Israel's actions during the Israel-Hamas War. In addition to starting the litigation process, South Africa also asked the International Court of Justice to demand that Israel cease their military operations in the Gaza Strip as a provisional measure.

Circular reporting

From Wikipedia, the free encyclopedia
https://en.wikipedia.org/wiki/Circular_reporting

Circular reporting, or false confirmation, is a situation in source criticism where a piece of information appears to come from multiple independent sources, but in reality comes from only one source. In many cases, the problem happens mistakenly through sloppy reporting or intelligence-gathering. However, the situation can also be intentionally contrived by the source or reporter as a way of reinforcing the widespread belief in its information.

Circular reporting occurs in a variety of fields, including intelligence gathering, journalism, and scholarly research. It is of particular concern in military intelligence because the original source has a higher likelihood of wanting to pass on misinformation, and because the chain of reporting is more prone to being obscured. It is also a problem in journalism and the development of conspiracy theories, in which the primary goal of a source spreading unlikely or hard-to-believe information is to make it appear to be widely known.

The case of the 2002 Niger uranium forgeries was a classic instance of circular reporting by intelligence agencies.

Examples of circular reporting

1976 novel Roots

Author Alex Haley grew up hearing the oral history that his family's first ancestor to enter the United States was a young man named Kunta Kinte, who lived near the Kamby Bolongo, or Gambia River, and was kidnapped into slavery when out gathering wood. As an adult, Haley researched his family genealogy for what would become the 1976 novel Roots: The Saga of an American Family, and he traveled to the Gambia in an attempt to confirm the family history of Kinte. Haley told the story of Kinte to a seminar of Gambian tribal experts, who searched for a griot—an oral historian—who might be able to confirm the story. Ultimately, Haley met a man named Kebba Fofana in the town of Juffure who was able to relate a story of Kunta Kinte that was strikingly similar to Haley's lifelong family history, an apparent confirmation that grounded Haley's novel (as well as the landmark 1977 miniseries adapted from the novel). After publication, however, it was discovered that griot oral histories were not reliable for dates before the 19th century, that Fofana was not a true griot, and that Fofana's confirmation of Haley's history was ultimately a retelling of the story Haley himself told Gambian experts.

Iraq War

In 2001, the Niger uranium forgeries, documents initially released by SISMI (the former military intelligence agency of Italy), seemed to depict an attempt made by Saddam Hussein in Iraq to purchase yellowcake uranium powder from Niger during the Iraq disarmament crisis. They were referenced by other intelligence agencies to convince their governments or public that such a purchase had taken place.

In 2004, the Chairman of the US Senate Report on Pre-war Intelligence on Iraq told NBC's Tim Russert that a single informant, 'Curveball' "had really provided 98 percent of the assessment as to whether or not the Iraqis had a biological weapon." This was despite the fact that "nobody inside the U.S. government had ever actually spoken to the informant—except [for a single] Pentagon analyst, who concluded the man was an alcoholic and utterly useless as a source."

Other examples

In early 2012, a TV Tropes user named Tunafish claimed that a bug existed in Civilization that caused Gandhi to be much more aggressive. Tunafish did not provide any proof. The repetition of this false information led to the "Nuclear Gandhi" internet meme.

In 2018, Shehroze Chaudhry was identified as an active member of the Islamic State who participated in the killing of several individuals, through reporting involving a New York Times podcast, among others. The podcast and other outlets referenced blog posts authored by Chaudhry starting in 2016. The podcast was taken by government officials and others as evidence of the crime; however, the original posts were unverified and later renounced by the author.

Circular reporting on Wikipedia

Wikipedia is sometimes criticized for being used as a source of circular reporting, particularly a variant where an unsourced claim in a Wikipedia article is repeated by a reliable source, often without citing the article; which is then added as a source to the claim on Wikipedia.

History of citogenesis

The *xkcd* comic strip that coined the term *citogenesis*

The first recorded use of the term citogenesis to describe this phenomenon was in November 2011, when Randall Munroe used it in an xkcd comic strip. The neologism is attributed as being a homophonic wordplay on 'cytogenesis', the formation, development and variation of biological cells.

An article in the magazine Slate referenced the four-step process described in the comic, to raise awareness about citogenesis as facilitated by Wikipedia. This type of circular reporting has been described as particularly hard-to-catch because of the speed of revisions of modern webpages, and the lack of "as of" timestamps in citations and "last updated" timestamps on pages online.

Inspired by the comic, Wikipedia editors have since maintained an internal list of citogenesis incidents to monitor its prevalence.

Wikipedia advises researchers and journalists to be wary of, and generally avoid, using Wikipedia as a direct source, and to focus instead on verifiable information found in an article's cited references. Researchers and Wikipedians alike are advised to note the retrieved-on date of any web citation, to support identification of the earliest source of a claim.

Examples on Wikipedia

Prominent examples of false claims that were propagated on Wikipedia and in news sources because of circular reporting:

2007: Wikipedia and The Independent propagated the false information that comedian Sacha Baron Cohen had worked at Goldman Sachs.
2008: A student arbitrarily added, "also known as....Brazilian Aardvarks" to the article on the coati, leading to subsequent commentary on the mammal that mentioned this nickname. Outlets repeating the nickname included The Independent, the Daily Express, the Metro, The Daily Telegraph, the Daily Mail, a book published by the University of Chicago, and a scholarly work published by the University of Cambridge.
2009: The middle name "Wilhelm" was falsely added into Karl-Theodor zu Guttenberg's name. This was propagated by a raft of publications, including German and international press.
2009: An incorrect release year of 1991 was added to the Wikipedia article of the Casio F-91W watch. The BBC repeated this in a 2011 article. Communication with primary sources repeatedly confirmed a 1989 release year, but because the BBC is usually a reliable secondary source, their use of 1991 made the misinformation difficult to remove. In 2019, KSNV cited this incident as another example of citogenesis. The correct year was only restored after that review, with the KSNV article becoming cited in the article to support restoring the 1989 release date.
2014: A statement was anonymously added to the Wikipedia page on UK comedian Dave Gorman stating that he had "taken a career break for a sponsored hitchhike around the Pacific Rim countries". When this was questioned, an article published at a later date (September 2014) in The Northern Echo, a daily regional newspaper in North East England was cited as evidence. Gorman repudiated the claim in episode 3, season 4 of his UK television show Modern Life Is Goodish (first broadcast 22 November 2016).
2022: A hoax article about Alan MacMasters, purported inventor of the toaster, was discovered to have been picked up in news media later used as citations.

Blood substitute

From Wikipedia, the free encyclopedia

A blood substitute (also called artificial blood or blood surrogate) is a substance used to mimic and fulfill some functions of biological blood. It aims to provide an alternative to blood transfusion, which is transferring blood or blood-based products from one person into another. Thus far, there are no well-accepted oxygen-carrying blood substitutes, which is the typical objective of a red blood cell transfusion; however, there are widely available non-blood volume expanders for cases where only volume restoration is required. These are helping doctors and surgeons avoid the risks of disease transmission and immune suppression, address the chronic blood donor shortage, and address the concerns of Jehovah's Witnesses and others who have religious objections to receiving transfused blood.^{[citation needed]}

The main categories of "oxygen-carrying" blood substitutes being pursued are hemoglobin-based oxygen carriers (HBOC) and perfluorocarbon emulsions. Oxygen therapeutics are in clinical trials in the U.S. and European Union, and Hemopure is available in South Africa.

History

After William Harvey discovered blood pathways in 1616, many people tried to use fluids such as beer, urine, milk, and non-human animal blood as blood substitute. Sir Christopher Wren suggested wine and opium as blood substitute.

At the beginning of the 20th century, the development of modern transfusion medicine initiated through the work of Landsteiner and co-authors opened the possibility to understanding the general principle of blood group serology. Simultaneously, significant progress was made in the fields of heart and circulation physiology as well as in the understanding of the mechanism of oxygen transport and tissue oxygenation.

Restrictions in applied transfusion medicine, especially in disaster situations such as World War II, laid the grounds for accelerated research in the field of blood substitutes. Early attempts and optimism in developing blood substitutes were very quickly confronted with significant side effects, which could not be promptly eliminated due to the level of knowledge and technology available at that time. The emergence of HIV in the 1980s renewed impetus for development of infection-safe blood substitutes. Public concern about the safety of the blood supply was raised further by mad cow disease. The continuous decline of blood donation combined with the increased demand for blood transfusion (increased ageing of population, increased incidence of invasive diagnostic, chemotherapy and extensive surgical interventions, terror attacks, international military conflicts) and positive estimation of investors in biotechnology branch made for a positive environment for further development of blood substitutes.

Efforts to develop blood substitutes have been driven by a desire to replace blood transfusion in emergency situations, in places where infectious disease is endemic and the risk of contaminated blood products is high, where refrigeration to preserve blood may be lacking, and where it might not be possible or convenient to find blood type matches.

In 2023, DARPA announced funding twelve universities and labs for synthetic blood research. Human trials would be expected to happen between 2028-2030.

Approaches

Efforts have focused on molecules that can carry oxygen, and most work has focused on recombinant hemoglobin, which normally carries oxygen, and perfluorocarbons (PFC), chemical compounds which can carry and release oxygen.

The first approved oxygen-carrying blood substitute was a perfluorocarbon-based product called Fluosol-DA-20, manufactured by Green Cross of Japan. It was approved by the Food and Drug Administration (FDA) in 1989. Because of limited success, complexity of use and side effects, it was withdrawn in 1994. However, Fluosol-DA remains the only oxygen therapeutic ever fully approved by the FDA. As of 2017 no hemoglobin-based product had been approved.

Perfluorocarbon based

Perfluorochemicals are not water soluble and will not mix with blood, therefore emulsions must be made by dispersing small drops of PFC in water. This liquid is then mixed with antibiotics, vitamins, nutrients and salts, producing a mixture that contains about 80 different components, and performs many of the vital functions of natural blood. PFC particles are about ⁠1/40⁠ the size of the diameter of a red blood cell (RBC). This small size can enable PFC particles to traverse capillaries through which no RBCs are flowing. In theory this can benefit damaged, blood-starved tissue, which conventional red cells cannot reach. PFC solutions can carry oxygen so well that mammals, including humans, can survive breathing liquid PFC solution, called liquid breathing.

Perfluorocarbon-based blood substitutes are completely man-made; this provides advantages over blood substitutes that rely on modified hemoglobin, such as unlimited manufacturing capabilities, ability to be heat-sterilized, and PFCs' efficient oxygen delivery and carbon dioxide removal. PFCs in solution act as an intravascular oxygen carrier to temporarily augment oxygen delivery to tissues. PFCs are removed from the bloodstream within 48 hours by the body's normal clearance procedure for particles in the blood – exhalation. PFC particles in solution can carry several times more oxygen per cubic centimeter (cc) than blood, while being 40 to 50 times smaller than hemoglobin.

Fluosol was made mostly of perfluorodecalin or perfluorotributylamine suspended in an albumin emulsion. It was developed in Japan and first tested in the United States in November 1979. In order to "load" sufficient amounts of oxygen into it, people who had been given it had to breathe pure oxygen by mask or in a hyperbaric chamber. It was approved by the FDA in 1989, and was approved in eight other countries. Its use was associated with a reduction in ischemic complications and with an increase in pulmonary edema and congestive heart failure. Due to difficulty with the emulsion storage of Fluosol use (frozen storage and rewarming), its popularity declined and its production ended in 1994.

Name	Sponsor	Description
Oxycyte	Oxygen Biotherapeutics	Tested in a Phase II-b Trials in the United States. Targeted as an oxygen therapeutic rather than a blood substitute, with successful small-scale open label human trials treating traumatic brain injury at Virginia Commonwealth University. The trial was later terminated.
PHER-O ₂	Sanguine Corp	In research
Perftoran	Russia	Contains perfluorodecalin and perfluoro-N-(4-methylcyclohexyl)-piperidine along with a surfactant, Proxanol-268. It was developed in Russia and as of 2005 was marketed there.
NVX-108	NuvOx Pharma	In a Phase Ib/II clinical trial where it raises tumor oxygen levels prior to radiation therapy in order to radiosensitize them.

Oxygent was a second-generation, lecithin-stabilized emulsion of a PFC that was under development by Alliance Pharmaceuticals. In 2002 a Phase III study was halted early due an increase in incidences of strokes in the study arm.

Haemoglobin based

Haemoglobin is the main component of red blood cells, comprising about 33% of the cell mass. Haemoglobin-based products are called haemoglobin-based oxygen carriers (HBOCs).

Unmodified cell-free haemoglobin is not useful as a blood substitute because its oxygen affinity is too high for effective tissue oxygenation, the half-life within the intravascular space that is too short to be clinically useful, it has a tendency to undergo dissociation in dimers with resultant kidney damage and toxicity, and because free haemoglobin tends to take up nitric oxide, causing vasoconstriction.

Efforts to overcome this toxicity have included making genetically engineered versions, cross-linking, polymerization, and encapsulation.

HemAssist, a diaspirin cross-linked haemoglobin (DCLHb) was developed by Baxter Healthcare; it was the most widely studied of the haemoglobin-based blood substitutes, used in more than a dozen animal and clinical studies. It reached Phase III clinical trials, in which it failed due to increased mortality in the trial arm, mostly due to severe vasoconstriction complications. The results were published in 1999.

Hemolink (Hemosol Inc., Mississauga, Canada) was a haemoglobin solution that contained cross-linked an o-rafinose polymerised human haemoglobin. Hemosol struggled after Phase II trials were halted in 2003 on safety concerns and declared bankruptcy in 2005.

Hemopure was developed by Biopure Corp and was a chemically stabilized, cross-linked bovine (cow) haemoglobin in a salt solution intended for human use; the company developed the same product under the trade name Oxyglobin for veterinary use in dogs. Oxyglobin was approved in the US and Europe and was introduced to veterinary clinics and hospitals in March 1998. Hemopure was approved in South Africa and Russia. Biopure filed for bankruptcy protection in 2009. Its assets were subsequently purchased by HbO2 Therapeutics in 2014.

PolyHeme was developed over 20 years by Northfield Laboratories and began as a military project following the Vietnam War. It is human haemoglobin, extracted from red blood cells, then polymerized, then incorporated into an electrolyte solution. In April 2009, the FDA rejected Northfield's Biologic License Application and in June 2009, Northfield filed for bankruptcy.

Dextran-Haemoglobin was developed by Dextro-Sang Corp as a veterinary product, and was a conjugate of the polymer dextran with human haemoglobin.

Hemotech was developed by HemoBiotech and was a chemically modified haemoglobin.

Somatogen developed a genetically engineered and crosslinked tetramer it called Optro. It failed in a phase II trial and development was halted.

A pyridoxylated Hb conjugated with polyoxyethylene was created by scientists at Ajinomoto and eventually developed by Apex Biosciences, a subsidiary of Curacyte AG; it was called "PHP" and failed in a Phase III trial published in 2014, due to increased mortality in the control arm, which led to Curacyte shutting down.

Similarly, Hemospan was developed by Sangart, and was a pegylated haemoglobin provided in a powdered form. While early trials were promising Sangart ran out of funding and closed down.

Stem cells

Stem cells offer a possible means of producing transfusable blood. A study performed by Giarratana et al. describes a large-scale ex-vivo production of mature human blood cells using hematopoietic stem cells. The cultured cells possessed the same haemoglobin content and morphology as native red blood cells. The authors contend that the cells had a near-normal lifespan, when compared to natural red blood cells.

Scientists from the experimental arm of the United States Department of Defense began creating artificial blood for use in remote areas and transfuse blood to wounded soldiers more quickly in 2010. The blood is made from the hematopoietic stem cells removed from the umbilical cord between human mother and newborn using a method called blood pharming. Pharming has been used in the past on animals and plants to create medical substances in large quantities. Each cord can produce approximately 20 units of blood. The blood is being produced for the Defense Advanced Research Projects Agency by Arteriocyte. The Food and Drug Administration has examined and approved the safety of this blood from previously submitted O-negative blood. Using this particular artificial blood will reduce the costs per unit of blood from $5,000 to equal or less than $1,000. This blood will also serve as a blood donor to all common blood types.

Sunday, February 9, 2025

Mental state

From Wikipedia, the free encyclopedia

https://en.wikipedia.org/wiki/Mental_state

A mental state, or a mental property, is a state of mind of a person. Mental states comprise a diverse class, including perception, pain/pleasure experience, belief, desire, intention, emotion, and memory. There is controversy concerning the exact definition of the term. According to epistemic approaches, the essential mark of mental states is that their subject has privileged epistemic access while others can only infer their existence from outward signs. Consciousness-based approaches hold that all mental states are either conscious themselves or stand in the right relation to conscious states. Intentionality-based approaches, on the other hand, see the power of minds to refer to objects and represent the world as the mark of the mental. According to functionalist approaches, mental states are defined in terms of their role in the causal network independent of their intrinsic properties. Some philosophers deny all the aforementioned approaches by holding that the term "mental" refers to a cluster of loosely related ideas without an underlying unifying feature shared by all. Various overlapping classifications of mental states have been proposed. Important distinctions group mental phenomena together according to whether they are sensory, propositional, intentional, conscious or occurrent. Sensory states involve sense impressions like visual perceptions or bodily pains. Propositional attitudes, like beliefs and desires, are relations a subject has to a proposition. The characteristic of intentional states is that they refer to or are about objects or states of affairs. Conscious states are part of the phenomenal experience while occurrent states are causally efficacious within the owner's mind, with or without consciousness. An influential classification of mental states is due to Franz Brentano, who argues that there are only three basic kinds: presentations, judgments, and phenomena of love and hate.

Mental states are usually contrasted with physical or material aspects. For (non-eliminative) physicalists, they are a kind of high-level property that can be understood in terms of fine-grained neural activity. Property dualists, on the other hand, claim that no such reductive explanation is possible. Eliminativists may reject the existence of mental properties, or at least of those corresponding to folk psychological categories such as thought and memory. Mental states play an important role in various fields, including philosophy of mind, epistemology and cognitive science. In psychology, the term is used not just to refer to the individual mental states listed above but also to a more global assessment of a person's mental health.

Definition

Various competing theories have been proposed about what the essential features of all mental states are, sometimes referred to as the search for the "mark of the mental". These theories can roughly be divided into epistemic approaches, consciousness-based approaches, intentionality-based approaches and functionalism. These approaches disagree not just on how mentality is to be defined but also on which states count as mental. Mental states encompass a diverse group of aspects of an entity, like this entity's beliefs, desires, intentions, or pain experiences. The different approaches often result in a satisfactory characterization of only some of them. This has prompted some philosophers to doubt that there is a unifying mark of the mental and instead see the term "mental" as referring to a cluster of loosely related ideas. Mental states are usually contrasted with physical or material aspects. This contrast is commonly based on the idea that certain features of mental phenomena are not present in the material universe as described by the natural sciences and may even be incompatible with it.

Epistemic and consciousness-based approaches

Epistemic approaches emphasize that the subject has privileged access to all or at least some of their mental states. It is sometimes claimed that this access is direct, private and infallible. Direct access refers to non-inferential knowledge. When someone is in pain, for example, they know directly that they are in pain, they do not need to infer it from other indicators like a body part being swollen or their tendency to scream when it is touched. But we arguably also have non-inferential knowledge of external objects, like trees or cats, through perception, which is why this criterion by itself is not sufficient. Another epistemic privilege often mentioned is that mental states are private in contrast to public external facts. For example, the fallen tree lying on a person's leg is directly open to perception by the bystanders while the victim's pain is private: only they know it directly while the bystanders have to infer it from their screams. It was traditionally often claimed that we have infallible knowledge of our own mental states, i.e. that we cannot be wrong about them when we have them. So when someone has an itching sensation, for example, they cannot be wrong about having this sensation. They can only be wrong about the non-mental causes, e.g. whether it is the consequence of bug bites or of a fungal infection. But various counterexamples have been presented to claims of infallibility, which is why this criterion is usually not accepted in contemporary philosophy. One problem for all epistemic approaches to the mark of the mental is that they focus mainly on conscious states but exclude unconscious states. A repressed desire, for example, is a mental state to which the subject lacks the forms of privileged epistemic access mentioned.

One way to respond to this worry is to ascribe a privileged status to conscious mental states. On such a consciousness-based approach, conscious mental states are non-derivative constituents of the mind while unconscious states somehow depend on their conscious counterparts for their existence.An influential example of this position is due to John Searle, who holds that unconscious mental states have to be accessible to consciousness to count as "mental" at all. They can be understood as dispositions to bring about conscious states. This position denies that the so-called "deep unconscious", i.e. mental contents inaccessible to consciousness, exists. Another problem for consciousness-based approaches, besides the issue of accounting for the unconscious mind, is to elucidate the nature of consciousness itself. Consciousness-based approaches are usually interested in phenomenal consciousness, i.e. in qualitative experience, rather than access consciousness, which refers to information being available for reasoning and guiding behavior. Conscious mental states are normally characterized as qualitative and subjective, i.e. that there is something it is like for a subject to be in these states. Opponents of consciousness-based approaches often point out that despite these attempts, it is still very unclear what the term "phenomenal consciousness" is supposed to mean. This is important because not much would be gained theoretically by defining one ill-understood term in terms of another. Another objection to this type of approach is to deny that the conscious mind has a privileged status in relation to the unconscious mind, for example, by insisting that the deep unconscious exists.

Intentionality-based approaches

Intentionality-based approaches see intentionality as the mark of the mental. The originator of this approach is Franz Brentano, who defined intentionality as the characteristic of mental states to refer to or be about objects. One central idea for this approach is that minds represent the world around them, which is not the case for regular physical objects. So a person who believes that there is ice cream in the fridge represents the world as being a certain way. The ice cream can be represented but it does not itself represent the world. This is why a mind is ascribed to the person but not to the ice cream, according to the intentional approach. One advantage of it in comparison to the epistemic approach is that it has no problems to account for unconscious mental states: they can be intentional just like conscious mental states and thereby qualify as constituents of the mind. But a problem for this approach is that there are also some non-mental entities that have intentionality, like maps or linguistic expressions. One response to this problem is to hold that the intentionality of non-mental entities is somehow derivative in relation to the intentionality of mental entities. For example, a map of Addis Ababa may be said to represent Addis Ababa not intrinsically but only extrinsically because people interpret it as a representation. Another difficulty is that not all mental states seem to be intentional. So while beliefs and desires are forms of representation, this seems not to be the case for pains and itches, which may indicate a problem without representing it. But some theorists have argued that even these apparent counterexamples should be considered intentional when properly understood.

Behaviorism and functionalism

Behaviorist definitions characterize mental states as dispositions to engage in certain publicly observable behavior as a reaction to particular external stimuli. On this view, to ascribe a belief to someone is to describe the tendency of this person to behave in certain ways. Such an ascription does not involve any claims about the internal states of this person, it only talks about behavioral tendencies. A strong motivation for such a position comes from empiricist considerations stressing the importance of observation and the lack thereof in the case of private internal mental states. This is sometimes combined with the thesis that we could not even learn how to use mental terms without reference to the behavior associated with them. One problem for behaviorism is that the same entity often behaves differently despite being in the same situation as before. This suggests that explanation needs to make reference to the internal states of the entity that mediate the link between stimulus and response. This problem is avoided by functionalist approaches, which define mental states through their causal roles but allow both external and internal events in their causal network.On this view, the definition of pain-state may include aspects such as being in a state that "tends to be caused by bodily injury, to produce the belief that something is wrong with the body and ... to cause wincing or moaning".

One important aspect of both behaviorist and functionalist approaches is that, according to them, the mind is multiply realizable. This means that it does not depend on the exact constitution of an entity for whether it has a mind or not. Instead, only its behavioral dispositions or its role in the causal network matter. The entity in question may be a human, an animal, a silicon-based alien or a robot. Functionalists sometimes draw an analogy to the software-hardware distinction where the mind is likened to a certain type of software that can be installed on different forms of hardware. Closely linked to this analogy is the thesis of computationalism, which defines the mind as an information processing system that is physically implemented by the neural activity of the brain.

One problem for all of these views is that they seem to be unable to account for the phenomenal consciousness of the mind emphasized by consciousness-based approaches. It may be true that pains are caused by bodily injuries and themselves produce certain beliefs and moaning behavior. But the causal profile of pain remains silent on the intrinsic unpleasantness of the painful experience itself. Some states that are not painful to the subject at all may even fit these characterizations.

Externalism

Theories under the umbrella of externalism emphasize the mind's dependency on the environment. According to this view, mental states and their contents are at least partially determined by external circumstances. For example, some forms of content externalism hold that it can depend on external circumstances whether a belief refers to one object or another. The extended mind thesis states that external circumstances not only affect the mind but are part of it. The closely related view of enactivism holds that mental processes involve an interaction between organism and environment.

Classifications of mental states

There is a great variety of types of mental states, which can be classified according to various distinctions. These types include perception, belief, desire, intention, emotion and memory. Many of the proposed distinctions for these types have significant overlaps and some may even be identical. Sensory states involve sense impressions, which are absent in non-sensory states. Propositional attitudes are mental states that have propositional contents, in contrast to non-propositional states. Intentional states refer to or are about objects or states of affairs, a feature which non-intentional states lack. A mental state is conscious if it belongs to a phenomenal experience. Unconscious mental states are also part of the mind but they lack this phenomenal dimension. Occurrent mental states are active or causally efficacious within the owner's mind while non-occurrent or standing states exist somewhere in the back of one's mind but do not currently play an active role in any mental processes. Certain mental states are rationally evaluable: they are either rational or irrational depending on whether they obey the norms of rationality. But other states are arational: they are outside the domain of rationality. A well-known classification is due to Franz Brentano, who distinguishes three basic categories of mental states: presentations, judgments, and phenomena of love and hate.

Types of mental states

There is a great variety of types of mental states including perception, bodily awareness, thought, belief, desire, motivation, intention, deliberation, decision, pleasure, emotion, mood, imagination and memory. Some of these types are precisely contrasted with each other while other types may overlap. Perception involves the use of senses, like sight, touch, hearing, smell and taste, to acquire information about material objects and events in the external world. It contrasts with bodily awareness in this sense, which is about the internal ongoings in our body and which does not present its contents as independent objects. The objects given in perception, on the other hand, are directly (i.e. non-inferentially) presented as existing out there independently of the perceiver. Perception is usually considered to be reliable but our perceptual experiences may present false information at times and can thereby mislead us. The information received in perception is often further considered in thought, in which information is mentally represented and processed. Both perceptions and thoughts often result in the formation of new or the change of existing beliefs. Beliefs may amount to knowledge if they are justified and true. They are non-sensory cognitive propositional attitudes that have a mind-to-world direction of fit: they represent the world as being a certain way and aim at truth. They contrast with desires, which are conative propositional attitudes that have a world-to-mind direction of fit and aim to change the world by representing how it should be. Desires are closely related to agency: they motivate the agent and are thus involved in the formation of intentions. Intentions are plans to which the agent is committed and which may guide actions. Intention-formation is sometimes preceded by deliberation and decision, in which the advantages and disadvantages of different courses of action are considered before committing oneself to one course. It is commonly held that pleasure plays a central role in these considerations. "Pleasure" refers to experience that feels good, that involves the enjoyment of something. The topic of emotions is closely intertwined with that of agency and pleasure. Emotions are evaluative responses to external or internal stimuli that are associated with a feeling of pleasure or displeasure and motivate various behavioral reactions. Emotions are quite similar to moods, some differences being that moods tend to arise for longer durations at a time and that moods are usually not clearly triggered by or directed at a specific event or object. Imagination is even further removed from the actual world in that it represents things without aiming to show how they actually are. All the aforementioned states can leave traces in memory that make it possible to relive them at a later time in the form of episodic memory.

Sensation, propositional attitudes and intentionality

An important distinction among mental states is between sensory and non-sensory states. Sensory states involve some form of sense impressions like visual perceptions, auditory impressions or bodily pains. Non-sensory states, like thought, rational intuition or the feeling of familiarity, lack sensory contents. Sensory states are sometimes equated with qualitative states and contrasted with propositional attitude states. Qualitative states involve qualia, which constitute the subjective feeling of having the state in question or what it is like to be in it. Propositional attitudes, on the other hand, are relations a subject has to a proposition. They are usually expressed by verbs like believe, desire, fear or hope together with a that-clause. So believing that it will rain today, for example, is a propositional attitude. It has been argued that the contrast between qualitative states and propositional attitudes is misleading since there is some form of subjective feel to certain propositional states like understanding a sentence or suddenly thinking of something. This would suggest that there are also non-sensory qualitative states and some propositional attitudes may be among them. Another problem with this contrast is that some states are both sensory and propositional. This is the case for perception, for example, which involves sensory impressions that represent what the world is like. This representational aspect is usually understood as involving a propositional attitude.

Closely related to these distinctions is the concept of intentionality. Intentionality is usually defined as the characteristic of mental states to refer to or be about objects or states of affairs. The belief that the moon has a circumference of 10921 km, for example, is a mental state that is intentional in virtue of being about the moon and its circumference. It is sometimes held that all mental states are intentional, i.e. that intentionality is the "mark of the mental". This thesis is known as intentionalism. But this view has various opponents, who distinguish between intentional and non-intentional states. Putative examples of non-intentional states include various bodily experiences like pains and itches. Because of this association, it is sometimes held that all sensory states lack intentionality. But such a view ignores that certain sensory states, like perceptions, can be intentional at the same time. It is usually accepted that all propositional attitudes are intentional. But while the paradigmatic cases of intentionality are all propositional as well, there may be some intentional attitudes that are non-propositional. This could be the case when an intentional attitude is directed only at an object. In this view, Elsie's fear of snakes is a non-propositional intentional attitude while Joseph's fear that he will be bitten by snakes is a propositional intentional attitude.

Conscious and unconscious

A mental state is conscious if it belongs to phenomenal experience. The subject is aware of the conscious mental states it is in: there is some subjective feeling to having them. Unconscious mental states are also part of the mind but they lack this phenomenal dimension. So it is possible for a subject to be in an unconscious mental state, like a repressed desire, without knowing about it. It is usually held that some types of mental states, like sensations or pains, can only occur as conscious mental states. But there are also other types, like beliefs and desires, that can be both conscious and unconscious. For example, many people share the belief that the moon is closer to the earth than to the sun. When considered, this belief becomes conscious, but it is unconscious most of the time otherwise. The relation between conscious and unconscious states is a controversial topic. It is often held that conscious states are in some sense more basic with unconscious mental states depending on them. One such approach states that unconscious states have to be accessible to consciousness, that they are dispositions of the subject to enter their corresponding conscious counterparts.On this position there can be no "deep unconscious", i.e. unconscious mental states that can not become conscious.

The term "consciousness" is sometimes used not in the sense of phenomenal consciousness, as above, but in the sense of access consciousness. A mental state is conscious in this sense if the information it carries is available for reasoning and guiding behavior, even if it is not associated with any subjective feel characterizing the concurrent phenomenal experience. Being an access-conscious state is similar but not identical to being an occurrent mental state, the topic of the next section.

Occurrent and standing

A mental state is occurrent if it is active or causally efficacious within the owner's mind. Non-occurrent states are called standing or dispositional states. They exist somewhere in the back of one's mind but currently play no active role in any mental processes. This distinction is sometimes identified with the distinction between phenomenally conscious and unconscious mental states. It seems to be the case that the two distinctions overlap but do not fully match despite the fact that all conscious states are occurrent. This is the case because unconscious states may become causally active while remaining unconscious. A repressed desire may affect the agent's behavior while remaining unconscious, which would be an example of an unconscious occurring mental state. The distinction between occurrent and standing is especially relevant for beliefs and desires. At any moment, there seems to be a great number of things we believe or things we want that are not relevant to our current situation. These states remain inactive in the back of one's head even though one has them. For example, while Ann is engaged in her favorite computer game, she still believes that dogs have four legs and desires to get a pet dog on her next birthday. But these two states play no active role in her current state of mind. Another example comes from dreamless sleep when most or all of our mental states are standing states.

Rational, irrational and arational

Certain mental states, like beliefs and intentions, are rationally evaluable: they are either rational or irrational depending on whether they obey the norms of rationality. But other states, like urges, experiences of dizziness or hunger, are arational: they are outside the domain of rationality and can be neither rational nor irrational. An important distinction within rationality concerns the difference between theoretical and practical rationality. Theoretical rationality covers beliefs and their degrees while practical rationality focuses on desires, intentions and actions. Some theorists aim to provide a comprehensive account of all forms of rationality but it is more common to find separate treatments of specific forms of rationality that leave the relation to other forms of rationality open.

There are various competing definitions of what constitutes rationality but no universally accepted answer. Some accounts focus on the relation between mental states for determining whether a given state is rational. In one view, a state is rational if it is well-grounded in another state that acts as its source of justification. For example, Scarlet's belief that it is raining in Manchester is rational because it is grounded in her perceptual experience of the rain while the same belief would be irrational for Frank since he lacks such a perceptual ground. A different version of such an approach holds that rationality is given in virtue of the coherence among the different mental states of a subject. This involves an holistic outlook that is less concerned with the rationality of individual mental states and more with the rationality of the person as a whole. Other accounts focus not on the relation between two or several mental states but on responding correctly to external reasons. Reasons are usually understood as facts that count in favor or against something. On this account, Scarlet's aforementioned belief is rational because it responds correctly to the external fact that it is raining, which constitutes a reason for holding this belief.

Classification according to Brentano

An influential classification of mental states is due to Franz Brentano. He argues that there are three basic kinds: presentations, judgments, and phenomena of love and hate. All mental states either belong to one of these kinds or are constituted by combinations of them. These different types differ not in content or what is presented but in mode or how it is presented. The most basic kind is presentation, which is involved in every mental state. Pure presentations, as in imagination, just show their object without any additional information about the veridical or evaluative aspects of their object. A judgment, on the other hand, is an attitude directed at a presentation that asserts that its presentation is either true or false, as is the case in regular perception. Phenomena of love and hate involve an evaluative attitude towards their presentation: they show how things ought to be, and the presented object is seen as either good or bad. This happens, for example, in desires. More complex types can be built up through combinations of these basic types. To be disappointed about an event, for example, can be construed as a judgment that this event happened together with a negative evaluation of it. Brentano's distinction between judgments, phenomena of love and hate, and presentations is closely related to the more recent idea of direction of fit between mental state and world, i.e. mind-to-world direction of fit for judgments, the world-to-mind direction of fit for phenomena of love and hate and null direction of fit for mere presentations. Brentano's tripartite system of classification has been modified in various ways by Brentano's students. Alexius Meinong, for example, divides the category of phenomena of love and hate into two distinct categories: feelings and desires. Uriah Kriegel is a contemporary defender of Brentano's approach to the classification of mental phenomena.

Academia

Discussions about mental states can be found in many areas of study.

In cognitive psychology and the philosophy of mind, a mental state is a kind of hypothetical state that corresponds to thinking and feeling, and consists of a conglomeration of mental representations and propositional attitudes. Several theories in philosophy and psychology try to determine the relationship between the agent's mental state and a proposition.

Instead of looking into what a mental state is, in itself, clinical psychology and psychiatry determine a person's mental health through a mental status examination.

Epistemology

Mental states also include attitudes towards propositions, of which there are at least two—factive and non-factive, both of which entail the mental state of acquaintance. To be acquainted with a proposition is to understand its meaning and be able to entertain it. The proposition can be true or false, and acquaintance requires no specific attitude towards that truth or falsity. Factive attitudes include those mental states that are attached to the truth of the proposition—i.e. the proposition entails truth. Some factive mental states include "perceiving that", "remembering that", "regretting that", and (more controversially) "knowing that". Non-factive attitudes do not entail the truth of the propositions to which they are attached. That is, one can be in one of these mental states and the proposition can be false. An example of a non-factive attitude is believing—people can believe a false proposition and people can believe a true proposition. Since there is the possibility of both, such mental states do not entail truth, and therefore, are not factive. However, belief does entail an attitude of assent toward the presumed truth of the proposition (whether or not it is so), making it and other non-factive attitudes different from a mere acquaintance.

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