Base rates and prevalence
About 8% of children and adolescents suffer from depression.
 This year, 51 percent of students (teens) who visited a counseling 
center reported having anxiety, followed by depression (41 percent), 
relationship concerns (34 percent) and suicidal ideation (20.5 percent).
 Many students reported experiencing multiple conditions at once. 
Research suggests that the prevalence of young depression sufferers in 
Western cultures ranges from 1.9% to 3.4% among primary school children 
and 3.2% to 8.9% among adolescents.
 Studies have also found that among children diagnosed with a depressive
 episode, there is a 70% rate of recurrence within five years. Furthermore, 50% of children with depression will have a recurrence at least once during their adulthood.
 While there is no gender difference in depression rates up until age 
15, after that age the rate among women doubles compared to men. 
However, in terms of recurrence rates and symptom severity, there is no 
gender difference.
 In an attempt to explain these findings, one theory asserts that 
preadolescent women, on average, have more risk factors for depression 
than men. These risk factors then combine with the typical stresses and 
challenges of adolescent development to trigger the onset of depression.
Suicidal intent
Like
 their adult counterparts, children and adolescent depression sufferers 
are at an increased risk of attempting or committing suicide. Suicide is the third leading cause of death among 15-19 year olds. Adolescent males may be at an even higher risk of suicidal behavior if they also present with a conduct disorder. In the 1990s, the National Institute of Mental Health (NIMH) found that up to 7% of adolescents who develop major depressive disorder may commit suicide as young adults.
 Such statistics demonstrate the importance of interventions by family 
and friends, as well as the importance of early diagnosis and treatment 
by medical staff, to prevent suicide among depressed or at-risk youth.
However, some data showed an opposite conclusion. Most depression 
symptoms are reported more frequently by females; such as sadness 
(reported by 85.1% of women and 54.3% of men), and crying (approximately
 63.4% of women and 42.9% of men). Women have a higher probability to 
experience depression than men, with the prevalences of 19.2% and 13.5% 
respectively.
Risk factor
In
 childhood, boys and girls appear to be at equal risk for depressive 
disorders; during adolescence, however, girls are twice as likely as 
boys to develop depression. Before adolescence rates of depression are 
about the same in girls and boys, it is not until between the ages of 
11-13 that is begins to change. Young girls around this age, physically,
 go through more changes than young boys which put that a higher risk 
for depression and hormonal imbalance. The gender gap in depression 
between adolescent men and women is mostly due to young women's lower 
levels of positive thinking, need for approval, and self-focusing 
negative conditions.
 Frequent exposure to victimization or bullying was related to high 
risks of depression, ideation and suicide attempts compare to those not 
involved in bullying. Nicotine dependence is also associated with depression, anxiety, and poor dieting, mostly in young men.  Although causal direction has not been established, involvement in any sex or drug use is cause for concern.
 Children who develop major depression are more likely to have a family 
history of the disorder (often a parent who experienced depression at an
 early age) than patients with adolescent- or adult-onset depression. 
Adolescents with depression are also likely to have a family history of 
depression, though the correlation is not as high as it is for children.
Comorbidity
Research has shown that there is a high rate of comorbidity with depression in children with dysthymia.
 There is also a substantial comorbidity rate with depression in 
children with anxiety disorder, conduct disorder, and impaired social 
functioning. Particularly, there is a high comorbidity rate with anxiety, ranging from 15.9% to 75%.
 Conduct disorders also have a significant comorbidity with depression 
in children and adolescents, with a rate of 23% in one longitudinal 
study.
 Beyond other clinical disorders, there is also an association between 
depression in childhood and poor psychosocial and academic outcomes, as 
well as a higher risk for substance abuse and suicide.
The prevalence of psychiatric comorbidities during adolescence may vary by race and ethnicity.
Diagnosis
According to the DSM-IV,
 children must exhibit either a depressed mood or a loss of interest or 
pleasure in normal activities. These activities may include school, 
extracurricular activities, or peer interactions. Depressive moods in 
children can be expressed as being unusually irritable, which may be 
displayed by "acting out," behaving recklessly, or often reacting with 
anger or hostility. Children who do not have the cognitive or language 
development to properly express mood states can also exhibit their mood 
through physical complaints such as showing sad facial expressions 
(frowning) and poor eye contact. A child must also exhibit four other 
symptoms in order to be clinically diagnosed. However, according to the 
Omnigraphics Health References Series: Depression Sourcebook, Third Edition,
 a more calculated evaluation must be given by a medical or mental 
health professional such as a physiologist or psychiatrist. Following 
the bases of symptoms, signs include, but are not limited to, an unusual
 change in sleep habits (for example, trouble sleeping or overly 
indulged sleeping hours); a significant amount of weight gain/loss by 
lack or excessive eating; experiencing aches/pains for no apparent 
reason that can found; and an inability to concentrate on tasks or 
activities. If these symptoms are present for a period of two weeks or 
longer, it is safe to make the assumption that the child, or anybody 
else for that matter, is falling into major depression.
Correlation between adolescent depression and adulthood obesity
According
 to research conducted by Laura P. Richardson et al., major depression 
occurred in 7% of the cohort during early adolescence (11, 13, and 15 
years of age) and 27% during late adolescence (18 and 21 years of age). 
At 26 years of age, 12% of study members were obese. After adjusting for
 each individual's baseline body mass index (calculated as the weight in
 kilograms divided by the square of height in meters), depressed late 
adolescent girls were at a greater than 2-fold increased risk for 
obesity in adulthood compared with their non-depressed female peers 
(relative risk, 2.32; 95% confidence interval, 1.29-3.83). A 
dose-response relationship between the number of episodes of depression 
during adolescence, and risk for adult obesity was also observed in 
female subjects. The association was not observed for late adolescent 
boys or for early adolescent boys or girls.
Correlation between child depression and adolescent cardiac risks
According
 to research by RM Carney et al., any history of child depression 
influences the occurrence of adolescent cardiac risk factors, even if 
individuals no longer suffer from depression. They are much more likely 
to develop heart disease as adults.
Distinction from major depressive disorder in adults
While
 there are many similarities to adult depression, especially in 
expression of symptoms, there are many differences that create a 
distinction between the two diagnoses. Research has shown that when a 
child’s age is younger at diagnosis, typically there will be a more 
noticeable difference in expression of symptoms from the classic signs 
in adult depression.
 One major difference between the symptoms exhibited in adults and in 
children is that children have higher rates of internalization; 
therefore, symptoms of child depression are more difficult to recognize.
 One major cause of this difference is that many of the neurobiological 
effects in the brain of adults with depression are not fully developed 
until adulthood. Therefore, in a neurological sense, children and 
adolescents express depression differently.
History
Professionals
 first became aware of child abuse in the early 1980s, so it is possible
 that some of the young people identified with depressive disorders may 
have had a history of sexual abuse, which was not disclosed. This raises
 the question of what the outcome would have been in those young people 
if they had disclosed the abuse and received appropriate therapeutic 
interventions. It is well-known that childhood sexual abuse is a 
significant factor in the history of some adults with depressive 
syndromes. 
In the past, attention deficit hyperactivity disorder (ADHD) was not recognized, and hyperkinetic disorder
 was only rarely diagnosed. Some young people, especially those with 
comorbid conduct disorder and major depressive disorder, may have had 
undiagnosed and untreated ADHD. Before the use of psycho-stimulants, 
some young people may have been more vulnerable to development of 
depressive syndromes because of untreated attentional and other 
behavioural problems which reduce their self-esteem. 
Although antidepressants
 were used by child and adolescent psychiatrists to treat major 
depressive disorder, they may not always have been used in young people 
with a comorbid conduct disorder because of the risks of overdose in 
such a population. Tricyclic antidepressant were the predominant antidepressants used at that time in this population. With the advent of selective serotonin re-uptake inhibitors
 (SSRIs), child and adolescent psychiatrists probably began prescribing 
more anti-depressants in the comorbid conduct disorder/major depressive 
group because of the lower risk of serious harm in overdose. This raises
 the possibility that more effective treatment of these young people 
might also improve their outcomes in adult life.
Assessments
Among
 the psychological assessments for identifying whether or not children 
and adolescents are experiencing depression or depressive symptoms is 
the Children's Depression Inventory.
 In early 2016, the USPSTF released an updated recommendation for the 
screening of adolescents ages 12 to 18 years for major depressive 
disorder (MDD). Appropriate treatment and follow-up should be provided 
for adolescents who screen positive.
Treatment
There are multiple treatments that can be effective in treating children diagnosed with depression. Psychotherapy
 and medications are commonly used treatment options. In some research, 
adolescents showed a preference for psychotherapy rather than 
antidepressant medication for treatment. For adolescents, cognitive behavioral therapy and interpersonal therapy have been empirically supported as effective treatment options.
 The use of antidepressant medication in children is often seen as a 
last resort; however, studies have shown that a combination of 
psychotherapy and medication is the most effective treatment. Pediatric massage therapy
 may have an immediate effect on a child's emotional state at the time 
of the massage, but sustained effects on depression have not been 
identified.
Treatment programs have been developed that help reduce the 
symptoms of depression. These treatments focus on immediate symptom 
reduction by concentrating on teaching children skills pertaining to 
primary and secondary control. While much research is still needed to 
confirm this treatment program’s efficacy, one study showed it to be 
effective in children with mild or moderate depressive symptoms.
Talk therapy
There are three common types of talk therapy. These can assist people to live more fully and have a better life.
 Men are encouraged to open up more emotionally and communicate their 
personal distress, while women are encouraged to be assertive of their 
own strengths.
Cognitive therapy
Cognitive therapy
 aims to change harmful ways of thinking and reframe negative thoughts 
in a more positive way. Aims of cognitive therapy include various steps 
of patient learning. They learn to monitor their negative thoughts, to 
become aware of the link between their thoughts, the affect their 
thoughts have on them & their behavior, to become aware of and 
change the negative, depressive thoughts which affect their health and 
state of mind 
Behavioral therapy
Behavioral therapy helps change harmful ways of acting and gain control over behavior which is causing problems.
Interpersonal therapy
Interpersonal therapy helps one learn to relate better with others, express feelings, and develop better social skills.
Psychotherapy
Psychotherapy teaches coping skills while allowing the teens or children to explore feelings and events in a safe environment.
Family therapy
The principles of group dynamics are relevant to family therapists who must not only work with individuals, but with entire family systems.
 Two key concepts that influence family therapy are the distinction 
between the process and content of group discussions, and role theory.
Therapists strive to understand not just what the group members 
say, but how these ideas are communicated (process). Therapists can help
 families improve the way they relate and thus enhance their own 
capacity to deal with the content of their problems by focusing on the 
process of their discussions.  Virginia Satir expanded on the concept of
 how individuals behave and communicate in groups by describing several 
family roles that can serve to stabilize expected characteristic 
behavior patterns in a family. For instance, if one child is considered 
to be a "rebel child", a sibling may take on the role of the "good 
child" to alleviate some of the stress in the family. This concept of 
role reciprocity is helpful in understanding family dynamics because the
 complementary nature of roles makes behaviors more resistant to change.
Controversies
Throughout
 the development and research of this disorder, controversies have 
emerged over the legitimacy of depression in childhood and adolescence 
as a diagnosis, the proper measurement and validity of scales to 
diagnose, and the safety of particular treatments.
Legitimacy as a diagnosis
In
 early research of depression in children, there was debate as to 
whether or not children could clinically fit the criteria for major depressive disorder.
 However, since the 1970s, it has been accepted among the psychological 
community that depression in children can be clinically significant.
 The more pertinent controversy in psychology today centers around the 
clinical significance of subthreshold mood disorders. This controversy 
stems from the debate regarding the definition of the specific criteria 
for a clinically significant depressed mood in relation to the cognitive
 and behavioral symptoms. Some psychologists argue that the effects of 
mood disorders in children and adolescents that exist (but do not fully 
meet the criteria for depression) do not have severe enough risks. Children in this area of severity, they argue, should receive some sort of treatment since the effects could still be severe.
 However, since there has yet to be enough research or scientific 
evidence to support that children that fall within the area just shy of a
 clinical diagnosis require treatment, other psychologists are hesitant 
to support the dispensation of treatment.
Diagnosis controversy
In
 order to diagnose a child with depression, different screening measures
 and reports have been developed to help clinicians make a proper 
decision. However, the accuracy and effectiveness of certain measures 
that help psychologists diagnose children have come into question. Questions have also surfaced about the safety and effectiveness of antidepressant medications.
Measurement reliability
The
 effectiveness of dimensional child self-report checklists has been 
criticized. Although literature has documented strong psychometric 
properties, other studies have shown a poor specificity at the top end 
of scales, resulting in most children with high scores not meeting the 
diagnostic criteria for depression.
  Another issue with reliability of measurement for diagnosis occurs in 
parent, teacher, and child reports. One study, which observed the 
similarities between child self-report and parent reports on the child's
 symptoms of depression, acknowledged that on more subjective symptom 
reports measures, the agreement was not significant enough to be 
considered reliable.
 Two self-report scales demonstrated an erroneous classification of 25% 
of children in both the depressed and controlled samples.
 A large concern in the use of self-report scales is the accuracy of the
 information collected. The main controversy is caused by uncertainty 
about how the data from these multiple informants can or should be 
combined to determine whether a child can be diagnosed with depression.
Treatment issues
The controversy over the use of antidepressants
 began in 2003 when Great Britain's Department of Health stated that, 
based on data collected by the Medicines and Healthcare products 
Regulatory Agency, paroxetine (an antidepressant) should not be used on patients under the age of 18. Since then, the United States Food and Drug Administration
 (FDA) has issued a warning describing the increased risk of adverse 
effects of antidepressants used as treatment in those under the age of 
18. The main concern is whether the risks outweigh the benefits of the 
treatment. In order to decide this, studies often look at the adverse 
effects caused by the medication in comparison to the overall symptom 
improvement.
 While multiple studies have shown an improvement or efficacy rate of 
over 50%, the concern of severe side effects – such as suicidal ideation
 or suicidal attempts, worsening of symptoms, or increase in hostility –
 are still concerns when using antidepressants.
 However, an analysis of multiple studies argues that while the risk of 
suicidal ideation or attempt is present, the benefits significantly 
outweigh the risks.
 Due to the variability of these studies, it is currently recommended 
that if antidepressants are chosen as a method of treatment for children
 or adolescents, the clinician monitor closely for adverse symptoms, 
since there is still no definitive answer on the safety and overall 
efficacy.
