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Native Americans in the United States have historically had extreme difficulty with the use of alcohol. Problems continue among contemporary Native Americans; 11.7% of the deaths among Native Americans and Alaska Natives are alcohol-related. Use of alcohol varies by age, gender and tribe with women, and older women in particular, being least likely to be regular drinkers. Native Americans, particularly women, are more likely to abstain entirely from alcohol than the general US population. Frequency of use among Native Americans is generally less than the general population, but the quantity consumed when it is consumed is generally greater.