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Social epidemiology focuses on the patterns in morbidity and mortality rates that emerge as a result of social characteristics. While an individual's lifestyle choices or family history may place him or her at an increased risk for developing certain illnesses, there are social inequalities in health that cannot be explained by individual factors. Variations in health outcomes in the United States are attributed to several social characteristics, such as gender, race, socioeconomic status, the environment, and educational attainment. Inequalities in any or all of these social categories can contribute to health disparities, with some groups placed at an increased risk for acquiring chronic diseases than others.

For example, cardiovascular disease is the leading cause of death in the United States, followed closely by cancer, with the fifth most deadly being diabetes. The general risk factors associated with these diseases include obesity and poor diet, tobacco and alcohol use, physical inactivity, and access to medical care and health information. Although it may seem that many these risk factors arise solely from individual health choices, such a view neglects the structural patterns in the choices that individuals make. Consequently, a person's likelihood for developing heart disease, cancer, or diabetes is in part correlated with social factors. Among all racial groups, individuals who are impoverished or low income, have lower levels of educational attainment, and/or live in lower-income neighborhoods are all more likely to develop chronic diseases, such as heart disease, cancer, and diabetes.

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