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Discrimination against drug addicts is a form of discrimination against individuals who suffer from a drug addiction. In the process of stigmatization, drug addicts are stereotyped as having a particular set of undesirable traits, in turn causing other individuals to act in a fearful or prejudicial manner toward them. Drug use discrimination also leads to many users being secretive about drug use. As it relates to healthcare stigmatizing attitudes surrounding drug use can cause barriers to treatment uptake and engagement. In some of its manifestations, discrimination against drug addicts involves a violation of human rights.

Drug abusers are often depicted as human beings who are not capable of staying drug free and are often addressed using derogatory terms. The reasoning for not helping patients seek the treatments needed are often due to the terms used to identify them, such as "crackhead" or "junkie". The name calling and stigma places a sense of shame for drug users for a disease that takes control of them physically and psychologically. Discrimination against drug abusers is very common in the workplace, and the most familiar example happens when employers give random drug test to see if the employee will pass it. However, according to the Rehabilitation Act of 1973, employers are supposed to ensure that alcoholics and other drug addicts get help and the accommodations that they need. The lack of job opportunities and treatment for drug addicts often results in relapses or in jail.

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