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Saturday, September 23, 2023

Animal Liberation Front

From Wikipedia, the free encyclopedia
 
Animal Liberation Front
FoundedJune 1976; 47 years ago
FocusAnimal rights
Location
  • Active in over 40 countries
OriginsUnited Kingdom
MethodDirect action
Websiteanimalliberationfrontline.com

The Animal Liberation Front (ALF) is an international, leaderless, decentralized political and social resistance movement that advocates and engages in what it calls non-violent direct action in protest against incidents of animal cruelty. It originated in the 1970s from the Bands of Mercy. Participants state it is a modern-day Underground Railroad, removing animals from laboratories and farms, destroying facilities, arranging safe houses, veterinary care and operating sanctuaries where the animals subsequently live. Critics have labelled them as eco-terrorists.

Active in over 40 countries, ALF cells operate clandestinely, consisting of small groups of friends and sometimes just one person, which makes internal movements difficult for the authorities to monitor. Robin Webb of the Animal Liberation Press Office has said: "That is why the ALF cannot be smashed, it cannot be effectively infiltrated, it cannot be stopped. You, each and every one of you: you are the ALF."

Activists say the movement is non-violent. According to the ALF's code, any act that furthers the cause of animal liberation, where all reasonable precautions are taken not to harm human or non-human life, may be claimed as an ALF action, including acts of vandalism causing economic damage. American activist Rod Coronado said in 2006: "One thing that I know that separates us from the people we are constantly accused of being—that is, terrorists, violent criminals—is the fact that we have harmed no one."

There has nevertheless been widespread criticism that ALF spokespersons and activists have either failed to condemn acts of violence or have themselves engaged in it, either in the name of the ALF or under another banner. The criticism has been accompanied by dissent within the animal rights movement itself about the use of violence, and increasing attention from the police and intelligence communities. In 2002, the Southern Poverty Law Center (SPLC), which monitors extremism in the United States, noted the involvement of the ALF in the Stop Huntingdon Animal Cruelty campaign, which SPLC identified as using terrorist tactics—though a later SPLC report also noted that they have not killed anyone. In 2005, the ALF was included in a United States Department of Homeland Security planning document listing a number of domestic terrorist threats on which the U.S. government expected to focus resources. That same year FBI deputy assistant director John Lewis stated that "eco terrorism" and the "animal rights movement" were "the number one domestic terrorism threat." In the UK, ALF actions are regarded as examples of domestic extremism, and are handled by the National Extremism Tactical Coordination Unit, set up in 2004 to monitor ALF and other illegal animal rights activity.

Origins

Band of Mercy

The roots of the ALF trace back to December 1963, when British journalist John Prestige was assigned to cover a Devon and Somerset Staghounds event, where he watched hunters chase and kill a pregnant deer. In protest, he formed the Hunt Saboteurs Association (HSA), which evolved into groups of volunteers trained to thwart the hunts' hounds by blowing horns and laying false scents.

Animal rights writer Noel Molland writes that one of these HSA groups was formed in 1971 by a law student from Luton named Ronnie Lee. In 1972, Lee and fellow activist Cliff Goodman decided more militant tactics were needed. They revived the name of a 19th-century RSPCA youth group, The Bands of Mercy, and with about half a dozen activists set up the Band of Mercy, which attacked hunters' vehicles by slashing tires and breaking windows, designed to stop the hunt from even beginning, rather than thwarting it once underway.

In 1973, the Band learned that Hoechst Pharmaceuticals was building a research laboratory in Milton Keynes. On 10 November 1973, two activists set fire to the building, causing £26,000 worth of damage, returning six days later to set fire to what was left of it. It was the animal liberation movement's first known act of arson. In June 1974, two Band activists set fire to boats taking part in the annual seal cull off the coast of Norfolk, which Molland writes was the last time the cull took place. Between June and August 1974, the Band launched eight raids against animal-testing laboratories, and others against chicken breeders and gun shops, damaging buildings or vehicles. Its first act of "animal liberation" took place during the same period when activists removed half a dozen guinea pigs from a guinea pig farm in Wiltshire, after which the owner closed the business, fearing further incidents. Then, as now, property crime caused a split within the fledgling movement. In July 1974, the Hunt Saboteurs Association offered a £250 reward for information leading to the identification of the Band of Mercy, telling the press, "We approve of their ideals, but are opposed to their methods."

ALF formed

In August 1974, Lee and Goodman were arrested for taking part in a raid on Oxford Laboratory Animal Colonies in Bicester, earning them the moniker the "Bicester Two". Daily demonstrations took place outside the court during their trial; Lee's local Labour MP, Ivor Clemitson, was one of their supporters. They were sentenced to three years in prison, during which Lee went on the movement's first hunger strike to obtain vegan food and clothing. They were paroled after 12 months, Lee emerging in the spring of 1976 more militant than ever. He gathered together the remaining Band of Mercy activists and two dozen new recruits, 30 in all. Molland writes that the Band of Mercy name sounded wrong as a description of what Lee saw as a revolutionary movement. Lee wanted a name that would haunt those who used animals, according to Molland. Thus, the Animal Liberation Front was born.

Structure and aims

Underground and above-ground

The movement has underground and above-ground components, and is entirely decentralized with no formal hierarchy, the absence of which acts as a firebreak when it comes to legal responsibility. Volunteers are expected to stick to the ALF's stated aims when using its banner:

  • To inflict economic damage on those who profit from the misery and exploitation of animals.
  • To liberate animals from places of abuse, i.e. laboratories, factory farms, fur farms etc., and place them in good homes where they may live out their natural lives, free from suffering.
  • To reveal the horror and atrocities committed against animals behind locked doors, by performing nonviolent direct actions and liberations
  • To take all necessary precautions against harming any animal, human and non-human.
  • Any group of people who are vegans and who carry out actions according to ALF guidelines have the right to regard themselves as part of the ALF.

A number of above-ground groups exist to support covert volunteers. The Animal Liberation Front Supporters Group (ALF SG) adopts activists in jail as prisoners of conscience; anyone can join the ALFSG for a small monthly fee. The Vegan Prisoners Support Group, created in 1994 when British activist Keith Mann was first jailed, works with prison authorities in the UK to ensure that ALF prisoners have access to vegan supplies. The Animal Liberation Press Office receives and publicizes anonymous communiqués from volunteers; it operates as an ostensibly independent group funded by public donations, though the High Court in London ruled in 2006 that its press officer in the UK, Robin Webb, was a pivotal figure in the ALF.

There are three publications associated with the ALF. Arkangel was a British bi-annual magazine founded by Ronnie Lee. Bite Back is a website where activists leave claims of responsibility; it published a "Direct Action Report" in 2005 stating that, in 2004 alone, ALF activists had removed 17,262 animals from facilities, and had claimed 554 acts of vandalism and arson. No Compromise is a San Francisco-based website that also reports on ALF actions.

Philosophy of direct action

ALF activists argue that animals should not be viewed as property, and that scientists and industry have no right to assume ownership of living beings who are the "subjects-of-a-life" in the words of philosopher Tom Regan. In the view of the ALF, to fail to recognize this is an example of speciesism—the ascription of different values to beings on the basis of their species membership alone, which they argue is as ethically flawed as racism or sexism. They reject the animal welfarist position that more humane treatment is needed for animals; they say their aim is empty cages, not bigger ones. Activists argue that the animals they remove from laboratories or farms are "liberated", not "stolen", because they were never rightfully owned in the first place.

"Labs raided, locks glued, products spiked, depots ransacked, windows smashed, construction halted, mink set free, fences torn down, cabs burnt out, offices in flames, car tyres es slashed, cages emptied, phone lines severed, slogans daubed, muck spread, damage done, electrics cut, site flooded, hunt dogs stolen, fur coats slashed, buildings destroyed, foxes freed, kennels attacked, businesses burgled, uproar, anger, outrage, balaclava clad thugs. It's an ALF thing!" — Keith Mann

Although the ALF members reject violence against people, many activists support property crime, comparing the destruction of animal laboratories and other facilities to resistance fighters blowing up gas chambers in Nazi Germany. Their argument for sabotage is that the removal of animals from a laboratory simply means they will be quickly replaced, but if the laboratory itself is destroyed, it not only slows down the restocking process, but increases costs, possibly to the point of making animal research prohibitively expensive; this, they argue, will encourage the search for alternatives. An ALF activist involved in an arson attack on the University of Arizona told No Compromise in 1996: "[I]t is much the same thing as the abolitionists who fought against slavery going in and burning down the quarters or tearing down the auction block ... Sometimes when you just take animals and do nothing else, perhaps that is not as strong a message."

The provision against violence in the ALF code has triggered divisions within the movement and allegations of hypocrisy from the ALF's critics. In 1998, terrorism expert Paul Wilkinson called the ALF and its splinter groups "the most serious domestic terrorist threat within the United Kingdom." In 1993, ALF was listed as an organization that has "claimed to have perpetrated acts of extremism in the United States" in the Report to Congress on the Extent and Effects of Domestic and International Terrorism on Animal Enterprises. It was named as a terrorist threat by the U.S. Department of Homeland Security in January 2005. In March 2005, a speech from the Counterterrorism Division of the FBI stated that: "The eco-terrorist movement has given rise and notoriety to groups such as the Animal Liberation Front, or ALF, and the Earth Liberation Front (ELF). These groups exist to commit serious acts of vandalism, and to harass and intimidate owners and employees of the business sector." In hearings held on 18 May 2005, before a Senate panel, officials of the FBI and the Bureau of Alcohol, Tobacco, Firearms, and Explosives (ATF) stated that "violent animal rights extremists and eco-terrorists now pose one of the most serious terrorism threats to the nation."  The use of the terrorist label has been criticized, however; the Southern Poverty Law Center, which tracks U.S. domestic extremism, writes that "for all the property damage they have wreaked, eco-radicals have killed no one." Philosopher and animal rights activist Steven Best writes that "given the enormity and magnitude of animal suffering ... one should notice that the ALF has demonstrated remarkable restraint in their war of liberation."

Best and trauma surgeon Jerry Vlasak, both of whom have volunteered for the North American press office, were banned from entering the UK in 2004 and 2005 after making statements that appeared to support violence against people. Vlasak told an animal rights conferences in 2003: "I don't think you'd have to kill—assassinate—too many vivisectors before you would see a marked decrease in the amount of vivisection going on. And I think for five lives, 10 lives, 15 human lives, we could save a million, two million, 10 million non-human animals." Best coined the term "extensional self-defence" to describe actions carried out in defense of animals by human beings acting as proxies. He argues that activists have the moral right to engage in acts of sabotage or even violence because animals are unable to fight back themselves. Best argues that the principle of extensional self-defense mirrors the penal code statues known as the necessity defense, which can be invoked when a defendant believes the illegal act was necessary to avoid imminent and great harm. Best argues that "extensional self defense" is not just a theory, but put into practice in some African countries, where hired armed soldiers occasionally use lethal force against poachers who would kill rhinos, elephants and other endangered animals for their body parts to be sold in international markets.

The nature of the ALF as a leaderless resistance means support for Vlasak and Best is hard to measure. An anonymous volunteer interviewed in 2005 for CBS's 60 Minutes said of Vlasak: "[H]e doesn't operate with our endorsement or our support or our appreciation, the support of the ALF. We have a strict code of non-violence ... I don't know who put Dr. Vlasak in the position he's in. It wasn't us, the ALF."

Philosopher Peter Singer of Princeton University has argued that ALF direct action can only be regarded as a just cause if it is non-violent, and that the ALF is at its most effective when uncovering evidence of animal abuse that other tactics could not expose. He cites 1984's "Unnecessary Fuss" campaign, when ALF raided the University of Pennsylvania's head-injury research clinic and removed footage showing researchers laughing at the brain damage of conscious baboons, as an example. The university responded that the treatment of the animals conformed to National Institutes of Health (NIH) guidelines, but as a result of the publicity, the lab was closed down, the chief veterinarian fired, and the university placed on probation. Barbara Orlans, a former animal researcher with the NIH, now with the Kennedy Institute of Ethics, writes that the case stunned the biomedical community, and is today considered one of the most significant cases in the ethics of using animals in research. Singer argues that if the ALF would focus on this kind of direct action, instead of sabotage, it would appeal to the minds of reasonable people. Against this, Steven Best writes that industries and governments have too much institutional and financial bias for reason to prevail.

Peter Hughes of the University of Sunderland cites a 1988 raid in the UK led by ALF activist Barry Horne as an example of positive ALF direct action. Horne and four other activists decided to free Rocky, a dolphin who had lived in a small concrete pool in Marineland in Morecambe for 20 years, by moving him 180 metres (590 ft) from his pool to the sea. The police spotted them carrying a homemade dolphin stretcher, and they were convicted of conspiracy to steal, but they continued to campaign for Rocky's release. Marineland eventually agreed to sell him for £120,000, money that was raised with the help of the Born Free Foundation and the Mail on Sunday, and in 1991 Rocky was transferred to an 80-acre (320,000 m2) lagoon reserve in the Turks and Caicos Islands, then released. Hughes writes that the ALF action helped to create a paradigm shift in the UK toward seeing dolphins as "individual actors", as a result of which, he writes, there are now no captive dolphins in the UK.

Early tactics and ideology

Rachel Monaghan of the University of Ulster writes that, in their first year of operation alone, ALF actions accounted for £250,000 worth of damage, targeting butcher shops, furriers, circuses, slaughterhouses, breeders, and fast-food restaurants. She writes that the ALF philosophy was that violence can only take place against sentient life forms, and therefore focusing on property destruction and the removal of animals from laboratories and farms was consistent with a philosophy of non-violence, despite the damage they were causing. In 1974, Ronnie Lee insisted that direct action be "limited only by reverence of life and hatred of violence", and in 1979, he wrote that many ALF raids had been called off because of the risk to life.

Kim Stallwood, a national organiser for the British Union for the Abolition of Vivisection (BUAV) in the 1980s, writes that the public's response to early ALF raids that removed animals was very positive, in large measure because of the non-violence policy. When Mike Huskisson removed three beagles from a tobacco study at ICI in June 1975, the media portrayed him as a hero. Robin Webb writes that ALF volunteers were viewed as the "Robin Hoods of the animal welfare world".

Stallwood writes that they saw ALF activism as part of their opposition to the state, rather than as an end-in-itself, and did not want to adhere to non-violence. In the early 1980s, the BUAV, an anti-vivisection group founded by Frances Power Cobbe in 1898, was among the ALF's supporters. Stallwood writes that it donated part of its office space rent-free to the ALF Supporters Group, and gave ALF actions uncritical support in its newspaper, The Liberator. In 1982, a group of ALF activists, including Roger Yates, now a sociologist at University College, Dublin, and Dave McColl, a director of Sea Shepherd Conservation Society, became members of the BUAV's executive committee, and used their position to radicalize the organization. Stallwood writes that the new executive believed all political action to be a waste of time, and wanted the BUAV to devote its resources exclusively to direct action. Whereas the earliest activists had been committed to rescuing animals, and destroyed property only where it contributed to the former, by the mid-1980s, Stallwood believed the ALF had lost its ethical foundation, and had become an opportunity "for misfits and misanthropes to seek personal revenge for some perceived social injustice". He writes: "Where was the intelligent debate about tactics and strategies that went beyond the mindless rhetoric and emotional elitism pervading much of the self-produced direct action literature? In short, what had happened to the animals' interests?" In 1984, the BUAV board reluctantly voted to expel the ALF SG from its premises and withdraw its political support, after which, Stallwood writes, the ALF became increasingly isolated.

Development of the ALF in the U.S.

There are conflicting accounts of when the ALF first emerged in the United States. The FBI writes that animal rights activists had a history of committing low-level criminal activity in the U.S. dating back to the 1970s. Freeman Wicklund and Kim Stallwood say that the first ALF action in the U.S. was on 29 May 1977, when researchers Ken LeVasseur and Steve Sipman released two dolphins, Puka and Kea, into the ocean from the University of Hawaii's Marine Mammal Laboratory. The North American Animal Liberation Press Office attributes the dolphin release to a group called Undersea Railroad, and says the first ALF action in the U.S. was, in fact, a raid on the New York University Medical Center on 14 March 1979, when activists removed one cat, two dogs, and two guinea pigs.

Kathy Snow Guillermo writes in Monkey Business that the first U.S. ALF action was the removal, on 22 September 1981, of the Silver Spring monkeys, 17 lab monkeys in the legal custody of People for the Ethical Treatment of Animals (PETA), after a researcher who had been experimenting on them was arrested for alleged violations of cruelty legislation. When the court ruled that the monkeys be returned to the researcher, they mysteriously disappeared, only to reappear five days later when PETA learned that legal action against the researcher could not proceed without the monkeys as evidence. Ingrid Newkirk, the president of PETA, writes that the first ALF cell was set up in late 1982, after a police officer she calls "Valerie" responded to the publicity triggered by the Silver Spring monkeys case, and flew to England to be trained by the ALF. Posing as a reporter, Valerie was put in touch with Ronnie Lee by Kim Stallwood, who at the time was working for the BUAV. Lee directed her to a training camp, where she was taught how to break into laboratories. Newkirk writes that Valerie returned to Maryland and set up an ALF cell, with the first raid taking place on 24 December 1982 against Howard University, where 24 cats were removed, some of whose back legs had been crippled. Jo Shoesmith, an American attorney and animal rights activist, says Newkirk's account of "Valerie" is not only fictionalized, as Newkirk acknowledges, but totally fictitious.

Two early ALF raids led to the closure of several university studies. A 28 May 1984 raid on the University of Pennsylvania's head injury clinic caused $60,000 worth of damage and saw the removal of 60 hours of tapes, which showed the researchers laughing as they used a hydraulic device to cause brain damage to baboons. The tapes were turned over to PETA, who produced a 26-minute video called Unnecessary Fuss. The head injury clinic was closed, the university's chief veterinarian was fired, and the university was put on probation.

On 20 April 1985, acting on a tip-off from a student, the ALF raided a laboratory in the University of California, Riverside, causing $700,000 in damages and removing 468 animals. These included Britches, a five-week-old macaque, who had been separated from his mother at birth and left alone with his eyes sewn shut and a sonar device on his head as part of a study into blindness. The raid, which was taped by the ALF, caused eight of the laboratory's seventeen active research projects to be shut down, and the university said years of medical research were lost. The raid prompted National Institutes of Health director James Wyngaarden to argue that the raids should be regarded as acts of terrorism.

Animal Rights Militia and Justice Department

Monaghan writes that, around 1982, there was a noticeable shift in the non-violent position, and not one approved by everyone in the movement. Some activists began to make personal threats against individuals, followed by letter bombs and threats to contaminate food, the latter representing yet another shift to threatening the general public, rather than specific targets.

In 1982, letter bombs were sent to all four major party leaders in the UK, including Prime Minister Margaret Thatcher. The first major food scare happened in November 1984, with the ALF claiming to the media that it had contaminated Mars Bars as part of a campaign to force the Mars company to stop conducting tooth decay tests on monkeys. On 17 November, the Sunday Mirror received a call from the ALF saying it had injected Mars Bars in stores throughout the country with rat poison. The call was followed by a letter containing a Mars Bar, presumed to be contaminated, and the claim that these were on sale in London, Leeds, York, Southampton, and Coventry. Millions of bars were removed from shelves and Mars halted production, at a cost to the company of $4.5 million. The ALF admitted the claims had been a hoax. Similar contamination claims were later made against L'Oréal and Lucozade.

The letter bombs were claimed by the Animal Rights Militia (ARM), although the initial statement in November 1984 by David Mellor, then a Home Office minister, stated that it was the Animal Liberation Front who had claimed responsibility. This is an early example of the shifting of responsibility from one banner to another depending on the nature of the act, with the ARM and another nom de guerre, the Justice Department—the latter first used in 1993—emerging as names for direct action that violated the ALF's "no harm to living beings" principle. Ronnie Lee, who had earlier insisted on the importance of the ALF's non-violence policy, seemed to support the idea. An article signed by RL—presumed to be Ronnie Lee—in the October 1984 ALF Supporters Group newsletter, suggested that activists set up "fresh groups ... under new names whose policies do not preclude the use of violence toward animal abusers".

No activist is known to have conducted operations under both the ALF and ARM banners, but overlap is assumed. Terrorism expert Paul Wilkinson has written that the ALF, the Justice Department, and the ARM are essentially the same thing, and Robert Garner of the University of Leicester writes that it would be pointless to argue otherwise, given the nature of the movement as a leaderless resistance. Robin Webb of the British Animal Liberation Press Office has acknowledged that the activists may be the same people: "If someone wishes to act as the Animal Rights Militia or the Justice Department, simply put, the ... policy of the Animal Liberation Front, to take all reasonable precautions not to endanger life, no longer applies."

From 1983 onwards, a series of fire bombs exploded in department stores that sold fur, with the intention of triggering the sprinkler systems in order to cause damage, although several stores were partly or completely destroyed. In September 1985, incendiary devices were placed under the cars of Sharat Gangoli and Stuart Walker, both animal researchers with the British Industrial Biological Research Association (BIBRA), wrecking both vehicles but with no injuries, and the ARM claimed responsibility. In January 1986, the ARM said it had placed devices under the cars of four employees of Huntingdon Life Sciences, timed to explode an hour apart from each other. A further device was placed under the car of Andor Sebesteny, a researcher for the Imperial Cancer Research Fund, which he spotted before it exploded. The next major attacks on individual researchers took place in 1990, when the cars of two veterinary researchers were destroyed by sophisticated explosive devices in two separate explosions. In February 1989, an explosion damaged the Senate House bar in Bristol University, an attack claimed by the unknown "Animal Abused Society". In June 1990, two days apart, bombs exploded in the cars of Margaret Baskerville, a veterinary surgeon working at Porton Down, a chemical research defence establishment, and Patrick Max Headley, a physiologist at Bristol University. Baskerville escaped without injury by jumping through the window of her mini-jeep when a bomb using a mercury-tilt device exploded next to the fuel tank. During the attack on Headley—which New Scientist writes involved the use of plastic explosives—a 13-month-old baby in a push-chair suffered flash burns, shrapnel wounds, and a partially severed finger. A wave of letter bombs followed in 1993, one of which was opened by the head of the Hereford site of GlaxoSmithKline, causing burns to his hands and face. Eleven similar devices were intercepted in postal sorting offices.

False flags and plausible deniability

The nature of the ALF exposes its name to the risk of being used by activists who reject its non-violence platform, or by opponents conducting so-called "false-flag" operations, designed to make the ALF appear violent. That same uncertainty provides genuine ALF activists with plausible deniability should an operation go wrong, by denying that the act was "authentically ALF".

Several incidents in 1989 and 1990 were described by the movement as false flag operations. In February 1989, an explosion damaged the Senate House bar in Bristol University, an attack claimed by the unknown "Animal Abused Society". In June 1990, two days apart, bombs exploded in the cars of Margaret Baskerville, a veterinary surgeon working at Porton Down, a chemical research defence establishment, and Patrick Max Headley, a professor of physiology at Bristol University. Baskerville escaped without injury by jumping through the window of her mini-jeep when a bomb using a mercury-tilt device exploded next to the fuel tank. During the attack on Headley—which New Scientist writes involved the use of plastic explosives—a 13-month-old baby in a push-chair suffered flash burns, shrapnel wounds to his back, and a partially severed finger.

No known entity claimed responsibility for the attacks, which were condemned within the animal rights movement and by ALF activists. Keith Mann writes that it did not seem plausible that activists known for making simple incendiary devices from household components would suddenly switch to mercury-tilt switches and plastic explosives, then never be heard from again. A few days after the bombings, the unknown "British Animal Rights Society" claimed responsibility for attaching a nail bomb to a Huntsman's Land Rover in Somerset. Forensic evidence led police to arrest the owner of the vehicle, who admitted he had bombed his own car to discredit the animal rights movement, and asked for two similar offences to be taken into consideration. He was jailed for nine months. The Baskerville and Headley bombers were never apprehended.

In 2018 the London Metropolitan Police apologised for the activities of one of their undercover agents who had infiltrated the group. A police officer using the name "Christine Green" had been involved in the illegal release of a large number of mink from a farm in Ringwood in 1998. The mission had been approved by senior officers in the police.

1996–present

Property destruction began to increase substantially after several high-profile campaigns closed down facilities perceived to be abusive to animals. Consort Kennels, a facility breeding beagles for animal testing; Hillgrove Farm, which bred cats; and Newchurch Farm, which bred guinea pigs, were all closed after being targeted by animal rights campaigns that appeared to involve the ALF. In the UK, the financial year 1991–1992 saw around 100 refrigerated meat trucks destroyed by incendiary devices at a cost of around £5 million. Butchers' locks were superglued, shrink-wrapped meats were pierced in supermarkets, slaughterhouses and refrigerated meat trucks were set on fire.

In 1999, ALF activists became involved in the international Stop Huntingdon Animal Cruelty (SHAC) campaign to close Huntingdon Life Sciences (HLS), Europe's largest animal-testing laboratory. The Southern Poverty Law Center, which monitors U.S. domestic extremism, has described SHAC's modus operandi as "frankly terroristic tactics similar to those of anti-abortion extremists". ALF activist Donald Currie was jailed for 12 years and placed on probation for life in December 2006 after being found guilty of planting homemade bombs on the doorsteps of businessmen with links to HLS. HLS director Brian Cass was attacked by men wielding pick-axe handles in February 2001. David Blenkinsop was one of those convicted of the attack, someone who in the past had conducted actions in the name of the ALF.

Also in 1999, a freelance reporter, Graham Hall, said he had been attacked after producing a documentary critical of the ALF, which was aired on Channel 4. The documentary showed ALF press officer Robin Webb appearing to give Hall—who was filming undercover while purporting to be an activist—advice about how to make an improvised explosive device, though Webb said his comments had been used out of context. Hall said that, as a result of the documentary, he was abducted, tied to a chair, and had the letters "ALF" branded on his back, before being released 12 hours later with a warning not to tell the police.

In June 2006, members of the ALF claimed responsibility for a firebomb attack on UCLA researcher Lynn Fairbanks, after a firebomb was placed on the doorstep of a house occupied by her 70-year-old tenant; according to the FBI, it was powerful enough to have killed the occupants, but failed to ignite. The attack was credited by the acting chancellor of UCLA as helping to shape the Animal Enterprise Terrorism Act. Animal liberation press officer Jerry Vlasak said of the attack: "force is a poor second choice, but if that's the only thing that will work ... there's certainly moral justification for that." As of 2008, activists were increasingly taking protests to the homes of researchers, staging "home demonstrations", which can involve making noise during the night, writing slogans on the researchers' property, smashing windows and spreading rumours to neighbours.

Operation Backfire

On 20 January 2006, as part of Operation Backfire, the U.S. Department of Justice announced charges against nine Americans and two Canadian activists calling themselves the "family". At least 9 of the 11 pleaded guilty to conspiracy and arson for their parts in a string of 20 arsons from 1996 through 2001, damage totalled $40 million. The Department of Justice called the acts examples of domestic terrorism. The incidents included arson attacks against meat-processing plants, lumber companies, a high-tension power line, and a ski centre, in Oregon, Wyoming, Washington, California and Colorado between 1996 and 2001.

Lobes of the brain

From Wikipedia, the free encyclopedia
 
Lobes of the cerebral cortex
(right hemisphere view)
Lateral surface. Four lobes visible.
 
Medial surface. Five lobes visible.
 
Identifiers
NeuroNames1210
NeuroLex IDbirnlex_922
TA98A14.1.09.005
TA25431
FMA77800

The lobes of the brain are the major identifiable zones of the human cerebral cortex, and they comprise the surface of each hemisphere of the cerebrum. The two hemispheres are roughly symmetrical in structure, and are connected by the corpus callosum. They traditionally have been divided into four lobes, but are today considered as having six lobes each. The lobes are large areas that are anatomically distinguishable, and are also functionally distinct to some degree. Each lobe of the brain has numerous ridges, or gyri, and furrows, the sulci that constitute further subzones of the cortex. The expression "lobes of the brain" usually refers only to those of the cerebrum, not to the distinct areas of the cerebellum.

Frontal lobe

The frontal lobe is located at the front of each cerebral hemisphere and positioned in front of the parietal lobe and above and in front of the temporal lobe. It is separated from the parietal lobe by a space between tissues called the central sulcus, and from the temporal lobe by a deep fold called the lateral sulcus also called the Sylvian fissure. The precentral gyrus, which forms the posterior border of the frontal lobe, contains the primary motor cortex (area 4 under the Brodmann area architecture) which controls voluntary movements of specific body parts. The precentral region also contains the premotor cortex (Brodmann area 6).

The frontal lobe contains most of the dopamine-delicate neurons in the cerebral cortex. The dopamine system is associated with reward, attention, short-term memory tasks, planning, and motivation. Dopamine tends to limit and select sensory information arriving from the thalamus to the forebrain. A report from the National Institute of Mental Health says a gene variant that reduces dopamine activity in the prefrontal cortex is related to poorer performance and inefficient functioning of that brain region during working memory tasks, and to a slightly increased risk for schizophrenia.

The frontal lobe consists of the prefrontal cortex which is located in the most anterior (farthest away) section of the frontal lobe. It is critical for one's working memory and executive control which helps keep goals and complex tasks organized.

The divisions of the prefrontal cortex include orbital, medial, and lateral prefrontal cortex. Within the lateral prefrontal cortex there are two different divisions: the dorsolateral and ventrolateral prefrontal cortex. The dorsolateral prefrontal cortex is located on top of the ventrolateral prefrontal cortex and is mainly responsible for the executive control and manipulation of memories that are retrieved through episodic memory. The ventrolateral prefrontal cortex is important for the regulation of meaningful stimuli that a person experiences throughout their lifetime, such as images, letters, and names.

Damage to the prefrontal cortex can result in issues with one's long term and short-term memories, as well as create changes in people's behaviors and their abilities to plan and organize.

Damage can result from lesions or tumors that have been surgically removed, and traumatic brain injuries (TBI) experienced from a severe hit to the head causing damage to the brain from swelling. Most often a TBI is experienced within a person's childhood from playing competitive sports or an accident from normal play. Having a traumatic brain injury can increase your chances of developing neurological psychiatric problems and abusing substances, such as cannabis, is known to be a risk factor in developing symptoms associated with schizophrenia. A study found that schizophrenia symptoms (hearing voices, talking to people who were not there, etc.) worsened after the usage of cannabis, suggesting that a TBI from childhood can enhance a development of psychosis due to the changes seen in the white matter within the frontal-temporal areas.

Parietal lobe

The parietal lobe is positioned above the occipital lobe and behind the frontal lobe and central sulcus.

The parietal lobe integrates sensory information among various modalities, including spatial sense and navigation (proprioception), the main sensory receptive area for the sense of touch (mechanoreception) in the somatosensory cortex which is just posterior to the central sulcus in the postcentral gyrus, and the dorsal stream of the visual system. The major sensory inputs from the skin (touch, temperature, and pain receptors), relay through the thalamus to the parietal lobe.

Several areas of the parietal lobe are important in language processing. The somatosensory cortex can be illustrated as a distorted figure — the homunculus (Latin: "little man"), in which the body parts are rendered according to how much of the somatosensory cortex is devoted to them. The superior parietal lobule and inferior parietal lobule are the primary areas of body or spatial awareness. A lesion commonly in the right superior or inferior parietal lobule leads to hemineglect.

Occipital lobe

The occipital lobe is the visual processing center of the mammalian brain containing most of the anatomical region of the visual cortex. The primary visual cortex is Brodmann area 17, commonly called V1 (visual one). Human V1 is located on the medial side of the occipital lobe within the calcarine sulcus; the full extent of V1 often continues onto the posterior pole of the occipital lobe. V1 is often also called striate cortex because it can be identified by a large stripe of myelin, the Stria of Gennari. Visually driven regions outside V1 are called extrastriate cortex. There are many extrastriate regions, and these are specialized for different visual tasks, such as visuospatial processing, color differentiation, and motion perception.

Temporal lobe

The temporal lobe is located beneath the lateral fissure on both cerebral hemispheres of the mammalian brain.

The temporal lobe is involved in processing sensory input into derived meanings for the appropriate retention of visual memories, language comprehension, and emotion association.

Within the temporal lobe is an area of the brain called the hippocampus which is associated with forming new memories and learning new things. The hippocampus has been studied many times in the past for its correlation with epilepsy showing there to be damage of this area. Although it has been difficult to determine the exact link between the temporal lobe and epilepsy, Chauvière (2020) suggests that there is a positive connection between the circuitry reorganization within the neurons and temporal lobe structure impacting rhythmic activities that are important for cognition.

Limbic lobe

The limbic lobe is an arc-shaped region of cortex on the medial surface of each cerebral hemisphere of the mammalian brain, consisting of parts of the frontal, parietal and temporal lobes. The term is ambiguous, with some authors including the paraterminal gyrus, the subcallosal area, the cingulate gyrus, the parahippocampal gyrus, the dentate gyrus, the hippocampus and the subiculum; while the Terminologia Anatomica includes the cingulate sulcus, the cingulate gyrus, the isthmus of cingulate gyrus, the fasciolar gyrus, the parahippocampal gyrus, the parahippocampal sulcus, the dentate gyrus, the fimbrodentate sulcus, the fimbria of hippocampus, the collateral sulcus, and the rhinal sulcus, and omits the hippocampus.

Insular cortex

The insular cortex is a portion of the cerebral cortex folded deep within the lateral sulcus (the fissure separating the temporal lobe from the parietal and frontal lobes). The insular cortex has an important function for sending axons to the amygdala and responding to tones and somatosensory stimulation.

Berret, et al. (2019) used mice to study the fear response that is associated with perceived threats from their memory of previously being shocked on their foot, finding adverse reflex responses in shocking stimulation whenever the insular cortex was silenced. This finding supports that the insular cortex takes information to specific amygdala subdivisions creating different components for fear behaviors.

The insulae are believed to be involved in consciousness and play a role in diverse functions usually linked to emotion or the regulation of the body's homeostasis. These functions include perception, motor control, self-awareness, cognitive functioning, and interpersonal experience. In relation to these, it is involved in psychopathology.

The insular cortex is divided into two parts: the larger anterior insula and the smaller posterior insula in which more than a dozen field areas have been identified. The cortical area overlying the insula toward the lateral surface of the brain is the operculum (meaning lid). The opercula are formed from parts of the enclosing frontal, temporal, and parietal lobes.

Parietal lobe

From Wikipedia, the free encyclopedia
 
Parietal lobe
Principal fissures and lobes of the cerebrum viewed laterally. (Parietal lobe is shown in yellow)
 
Lateral surface of left cerebral hemisphere, viewed from the side. (Parietal lobe is shown in orange.)
Details
Pronunciation/pəˈr.ə.tl/)
Part ofCerebrum
ArteryAnterior cerebral
Middle cerebral
VeinSuperior sagittal sinus
Identifiers
Latinlobus parietalis
MeSHD010296
NeuroNames95
NeuroLex IDbirnlex_1148
TA98A14.1.09.123
TA25467
FMA61826

The parietal lobe is one of the four major lobes of the cerebral cortex in the brain of mammals. The parietal lobe is positioned above the temporal lobe and behind the frontal lobe and central sulcus.

The parietal lobe integrates sensory information among various modalities, including spatial sense and navigation (proprioception), the main sensory receptive area for the sense of touch in the somatosensory cortex which is just posterior to the central sulcus in the postcentral gyrus, and the dorsal stream of the visual system. The major sensory inputs from the skin (touch, temperature, and pain receptors), relay through the thalamus to the parietal lobe.

Several areas of the parietal lobe are important in language processing. The somatosensory cortex can be illustrated as a distorted figure – the cortical homunculus (Latin: "little man") in which the body parts are rendered according to how much of the somatosensory cortex is devoted to them. The superior parietal lobule and inferior parietal lobule are the primary areas of body or spatial awareness. A lesion commonly in the right superior or inferior parietal lobule leads to hemineglect.

The name comes from the parietal bone, which is named from the Latin paries-, meaning "wall".

Structure

Animation. Parietal lobe (red) of left cerebral hemisphere.

The parietal lobe is defined by three anatomical boundaries: The central sulcus separates the parietal lobe from the frontal lobe; the parieto-occipital sulcus separates the parietal and occipital lobes; the lateral sulcus (sylvian fissure) is the most lateral boundary, separating it from the temporal lobe; and the longitudinal fissure divides the two hemispheres. Within each hemisphere, the somatosensory cortex represents the skin area on the contralateral surface of the body.

Immediately posterior to the central sulcus, and the most anterior part of the parietal lobe, is the postcentral gyrus (Brodmann area 3), the primary somatosensory cortical area. Separating this from the posterior parietal cortex is the postcentral sulcus.

The posterior parietal cortex can be subdivided into the superior parietal lobule (Brodmann areas 5 + 7) and the inferior parietal lobule (39 + 40), separated by the intraparietal sulcus (IPS). The intraparietal sulcus and adjacent gyri are essential in guidance of limb and eye movement, and—based on cytoarchitectural and functional differences—is further divided into medial (MIP), lateral (LIP), ventral (VIP), and anterior (AIP) areas.

Function

Functions of the parietal lobe include:

  • Two point discrimination – through touch alone without other sensory input (e.g. visual)
  • Graphesthesia – recognizing writing on skin by touch alone
  • Touch localization (bilateral simultaneous stimulation)

The parietal lobe plays important roles in integrating sensory information from various parts of the body, knowledge of numbers and their relations, and in the manipulation of objects. Its function also includes processing information relating to the sense of touch. Portions of the parietal lobe are involved with visuospatial processing. Although multisensory in nature, the posterior parietal cortex is often referred to by vision scientists as the dorsal stream of vision (as opposed to the ventral stream in the temporal lobe). This dorsal stream has been called both the "where" stream (as in spatial vision) and the "how" stream (as in vision for action). The posterior parietal cortex (PPC) receives somatosensory and visual input, which then, through motor signals, controls movement of the arm, hand, and eyes.

Various studies in the 1990s found that different regions of the posterior parietal cortex in macaques represent different parts of space.

  • The lateral intraparietal (LIP) area contains a map of neurons (retinotopically-coded when the eyes are fixed[11]) representing the saliency of spatial locations, and attention to these spatial locations. It can be used by the oculomotor system for targeting eye movements, when appropriate.
  • The ventral intraparietal (VIP) area receives input from a number of senses (visual, somatosensory, auditory, and vestibular). Neurons with tactile receptive fields represent space in a head-centered reference frame. The cells with visual receptive fields also fire with head-centered reference frames but possibly also with eye-centered coordinates
  • The medial intraparietal (MIP) area neurons encode the location of a reach target in eye-centered coordinates.
  • The anterior intraparietal (AIP) area contains neurons responsive to shape, size, and orientation of objects to be grasped as well as for manipulation of the hands themselves, both to viewed and remembered stimuli. The AIP has neurons that are responsible for grasping and manipulating objects through motor and visual inputs. The AIP and ventral premotor together are responsible for visuomotor transformations for actions of the hand.

More recent fMRI studies have shown that humans have similar functional regions in and around the intraparietal sulcus and parietal-occipital junction. The human "parietal eye fields" and "parietal reach region", equivalent to LIP and MIP in the monkey, also appear to be organized in gaze-centered coordinates so that their goal-related activity is "remapped" when the eyes move.

Emerging evidence has linked processing in the inferior parietal lobe to declarative memory. Bilateral damage to this brain region does not cause amnesia however the strength of memory is diminished, details of complex events become harder to retrieve, and subjective confidence in memory is very low. This has been interpreted as reflecting either deficits in internal attention, deficits in subjective memory states, or problems with the computation that allows evidence to accumulate, thus allowing decisions to be made about internal representations.

Clinical significance

Features of parietal lobe lesions are as follows:

  • Unilateral parietal lobe
    • Contralateral hemisensory loss
    • Astereognosis – inability to determine 3-D shape by touch.
    • Agraphaesthesia – inability to read numbers or letters drawn on hand, with eyes shut.
    • Contralateral homonymous inferior quadrantanopia
    • Asymmetry of optokinetic nystagmus (OKN)
    • Sensory seizures
  • Dominant hemisphere
    • Conduction aphasia
    • Dyslexia – a general term for disorders that can involve difficulty in learning to read or interpret words, letters, and other symbols
    • Apraxia – inability to perform complex movements in the presence of normal motor, sensory and cerebellar function
    • Gerstmann syndrome – characterized by acalculia, agraphia, finger agnosia, and left-right disorientation
  • Non-dominant hemisphere
  • Bilateral hemispheres

Damage to this lobe in the right hemisphere results in the loss of imagery, visualization of spatial relationships and neglect of left-side space and left side of the body. Even drawings may be neglected on the left side. Damage to this lobe in the left hemisphere will result in problems in mathematics, long reading, writing, and understanding symbols. The parietal association cortex enables individuals to read, write, and solve mathematical problems. The sensory inputs from the right side of the body go to the left side of the brain and vice versa.

The syndrome of hemispatial neglect is usually associated with large deficits of attention of the non-dominant hemisphere. Optic ataxia is associated with difficulties reaching toward objects in the visual field opposite to the side of the parietal damage. Some aspects of optic ataxia have been explained in terms of the functional organization described above.

Apraxia is a disorder of motor control which can be referred neither to "elemental" motor deficits nor to general cognitive impairment. The concept of apraxia was shaped by Hugo Liepmann about a hundred years ago. Apraxia is predominantly a symptom of left brain damage, but some symptoms of apraxia can also occur after right brain damage.

Amorphosynthesis is a loss of perception on one side of the body caused by a lesion in the parietal lobe. Usually, left-sided lesions cause agnosia, a full-body loss of perception, while right-sided lesions cause lack of recognition of the person's left side and extrapersonal space. The term amorphosynthesis was coined by D. Denny-Brown to describe patients he studied in the 1950s.

Can also result in sensory impairment where one of the affected person's senses (sight, hearing, smell, touch, taste and spatial awareness) is no longer normal.

Toxin

From Wikipedia, the free encyclopedia
The Amanita muscaria mushroom, an iconic toxic mushroom.

A toxin is a naturally occurring organic poison produced by metabolic activities of living cells or organisms. They occur especially as proteins, often conjugated. The term was first used by organic chemist Ludwig Brieger (1849–1919) and is derived from the word "toxic".

Toxins can be small molecules, peptides, or proteins that are capable of causing disease on contact with or absorption by body tissues interacting with biological macromolecules such as enzymes or cellular receptors. They vary greatly in their toxicity, ranging from usually minor (such as a bee sting) to potentially fatal even at extremely low doses (such as botulinum toxin).

Terminology

Toxins are often distinguished from other chemical agents strictly based on their biological origin.

Less strict understandings embrace naturally occurring non-organic toxins, such as arsenic. Other understandings embrace synthetic analogs of naturally occurring organic poisons as toxins, and may or may not embrace naturally occurring non-organic poisons. It is important to confirm usage if a common understanding is critical.

Toxins are a subset of toxicants. The term toxicant is preferred when the poison is man-made and therefore artificial. The human and scientific genetic assembly of a natural-based toxin should be considered a toxin as it is identical to its natural counterpart. The debate is one of linguistic semantics.

The word toxin does not specify method of delivery (as opposed to venom, a toxin delivered via a bite, sting, etc.). Poison is a related but broader term that encompasses both toxins and toxicants; poisons may enter the body through any means - typically inhalation, ingestion, or skin absorption. Toxin, toxicant, and poison are often used interchangeably despite these subtle differences in definition. The term toxungen has also been proposed to refer to toxins that are delivered onto the body surface of another organism without an accompanying wound.

A rather informal terminology of individual toxins relates them to the anatomical location where their effects are most notable:

On a broader scale, toxins may be classified as either exotoxins, excreted by an organism, or endotoxins, which are released mainly when bacteria are lysed.

Biological

The term "biotoxin" is sometimes used to explicitly confirm the biological origin as opposed to environmental or anthropogenic origins. Biotoxins can be classified by their mechanism of delivery as poisons (passively transferred via ingestion, inhalation, or absorption across the skin), toxungens (actively transferred to the target's surface by spitting, spraying, or smearing), or venoms (delivered through a wound generated by a bite, sting, or other such action). They can also be classified by their source, such as fungal biotoxins, microbial toxins, plant biotoxins, or animal biotoxins.

Toxins produced by microorganisms are important virulence determinants responsible for microbial pathogenicity and/or evasion of the host immune response.

Biotoxins vary greatly in purpose and mechanism, and can be highly complex (the venom of the cone snail can contain over 100 unique peptides, which target specific nerve channels or receptors).

Biotoxins in nature have two primary functions:

Some of the more well known types of biotoxins include:

Weaponry

Many living organisms employ toxins offensively or defensively. A relatively small number of toxins are known to have the potential to cause widespread sickness or casualties, but these may be appealing to those who would use them nefariously for several reasons. They are often inexpensive and easily available, and in some cases it is possible to refine them outside the laboratory. As biotoxins act quickly, and are highly toxic even at low doses, they can be more efficient than chemical agents. Due to these factors, it is vital to raise awareness of the clinical symptoms of biotoxin poisoning, and to develop effective countermeasures including rapid investigation, response, and treatment.

Environmental

The term "environmental toxin" can sometimes explicitly include synthetic contaminants such as industrial pollutants and other artificially made toxic substances. As this contradicts most formal definitions of the term "toxin", it is important to confirm what the researcher means when encountering the term outside of microbiological contexts.

Environmental toxins from food chains that may be dangerous to human health include:

Research

In general, when scientists determine the amount of a substance that may be hazardous for humans, animals and/or the environment they determine the amount of the substance likely to trigger effects and if possible establish a safe level. In Europe, the European Food Safety Authority produced risk assessments for more than 4,000 substances in over 1,600 scientific opinions and they provide open access summaries of human health, animal health and ecological hazard assessments in their OpenFoodTox database. The OpenFoodTox database can be used to screen potential new foods for toxicity.

The Toxicology and Environmental Health Information Program (TEHIP) at the United States National Library of Medicine (NLM) maintains a comprehensive toxicology and environmental health web site that includes access to toxins-related resources produced by TEHIP and by other government agencies and organizations. This web site includes links to databases, bibliographies, tutorials, and other scientific and consumer-oriented resources. TEHIP also is responsible for the Toxicology Data Network (TOXNET), an integrated system of toxicology and environmental health databases that are available free of charge on the web.

TOXMAP is a Geographic Information System (GIS) that is part of TOXNET. TOXMAP uses maps of the United States to help users visually explore data from the United States Environmental Protection Agency's (EPA) Toxics Release Inventory and Superfund Basic Research Programs.

Uncertainty quantification

From Wikipedia, the free encyclopedia https://en.wikipedia.org/wiki/Uncertainty_quantification ...