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Sleep-learning (also known as hypnopædia, or hypnopedia) is an attempt to convey information to a sleeping person, typically by playing a sound recording to them while they sleep. Although often used in pop culture as a way to introduce new information (see 'In Fiction'), sleep is considered an important period for memory consolidation.

Although learning new information during sleep has not been considered possible, at least to the extent it is used in fiction, the term hypnopedia has also been used to refer to the technique of exposing someone to sounds or odors during sleep in attempts to boost memory for previously learned information. Hypnopedia, in this sense, is related to a technique now known as Targeted Memory Reactivation (TMR). Unlike the pop-culture idea of sleep-learning, or learning new information during sleep, TMR pairs newly acquired information with sounds that can later be played, or cued, during electroencephalography (EEG) verified sleep to strengthen memory. This type of sleep reactivation in humans has been found successful in strengthening memory in a number of different paradigms including language learning, motor-skill learning, and spatial memory. Research in TMR has shown that cueing sounds that are associated with previously learned material over a period of sleep is more beneficial to memory than a similar period of wake. Likewise, cued material is also better preserved than material that is not cued during sleep.

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