Propagator

From Wikipedia, the free encyclopedia

In quantum mechanics and quantum field theory, the propagator is a function that specifies the probability amplitude for a particle to travel from one place to another in a given time, or to travel with a certain energy and momentum. In Feynman diagrams, which serve to calculate the rate of collisions in quantum field theory, virtual particles contribute their propagator to the rate of the scattering event described by the respective diagram. These may also be viewed as the inverse of the wave operator appropriate to the particle, and are, therefore, often called (causal) Green's functions (called "causal" to distinguish it from the elliptic Laplacian Green's function).

Non-relativistic propagators

In non-relativistic quantum mechanics, the propagator gives the probability amplitude for a particle to travel from one spatial point at one time to another spatial point at a later time. It is the Green's function (fundamental solution) for the Schrödinger equation. This means that, if a system has Hamiltonian H, then the appropriate propagator is a function

${\displaystyle G(x,t;x',t')={\frac {1}{i\hbar }}\Theta (t-t')K(x,t;x',t')}$

satisfying

${\displaystyle \left(i\hbar {\frac {\partial }{\partial t}}-H_{x}\right)G(x,t;x',t')=\delta (x-x')\delta (t-t')~,}$

where H_x denotes the Hamiltonian written in terms of the x coordinates, δ(x) denotes the Dirac delta-function, Θ(t) is the Heaviside step function and K(x, t ;x′, t′) is the kernel of the differential operator in question, often referred to as the propagator instead of G in this context, and henceforth in this article. This propagator can also be written as

${\displaystyle K(x,t;x',t')=\left\langle x\mid {\hat {U}}(t,t')\mid x'\right\rangle ,}$

where Û(t, t′) is the unitary time-evolution operator for the system taking states at time t′ to states at time t.

The quantum mechanical propagator may also be found by using a path integral,

${\displaystyle K(x,t;x',t')=\int \exp \left[{\frac {i}{\hbar }}\int _{t}^{t'}L({\dot {q}},q,t)\,dt\right]D[q(t)]}$

where the boundary conditions of the path integral include q(t) = x, q(t′) = x′. Here L denotes the Lagrangian of the system. The paths that are summed over move only forwards in time, and are integrated with the differential ${\displaystyle D[q(t)]}$ which follows the path in time.

In non-relativistic quantum mechanics, the propagator lets you find the wave function of a system given an initial wave function and a time interval. The new wave function is given by the equation

${\displaystyle \psi (x,t)=\int _{-\infty }^{\infty }\psi (x',t')K(x,t;x',t')\,dx'.}$

If K(x,t;x′,t′) only depends on the difference x − x′, this is a convolution of the initial wave function and the propagator. This kernel is the kernel of integral transform.

Basic examples: propagator of free particle and harmonic oscillator

For a time-translationally invariant system, the propagator only depends on the time difference t − t′, so it may be rewritten as

${\displaystyle K(x,t;x',t')=K(x,x';t-t').}$

The propagator of a one-dimensional free particle, with the far-right expression obtained via saddle-point methods, is then

${\displaystyle K(x,x';t)={\frac {1}{2\pi }}\int _{-\infty }^{+\infty }dk\,e^{ik(x-x')}e^{-{\frac {i\hbar k^{2}t}{2m}}}=\left({\frac {m}{2\pi i\hbar t}}\right)^{\frac {1}{2}}e^{-{\frac {m(x-x')^{2}}{2i\hbar t}}}.}$

Similarly, the propagator of a one-dimensional quantum harmonic oscillator is the Mehler kernel,^[3][4]

${\displaystyle K(x,x';t)=\left({\frac {m\omega }{2\pi i\hbar \sin \omega t}}\right)^{\frac {1}{2}}\exp \left(-{\frac {m\omega ((x^{2}+x'^{2})\cos \omega t-2xx')}{2i\hbar \sin \omega t}}\right)~.}$

The latter may be obtained from the previous free particle result upon making use of van Kortryk's SU(2) Lie-group identity,

${\displaystyle \exp \left(-{\frac {it}{\hbar }}\left({\frac {1}{2m}}~{\mathsf {p}}^{2}+{\frac {1}{2}}~m\omega ^{2}{\mathsf {x}}^{2}\right)\right)}$

${\displaystyle =\exp \left(-{\frac {im\omega }{2\hbar }}~{\mathsf {x}}^{2}\tan \left({\frac {\omega t}{2}}\right)\right)\exp \left(-{\frac {i}{2m\omega \hbar }}~{\mathsf {p}}^{2}\sin \left(\omega t\right)\right)\exp \left(-{\frac {im\omega }{2\hbar }}~{\mathsf {x}}^{2}\tan \left({\frac {\omega t}{2}}\right)\right)~,}$

valid for operators ${\displaystyle {\mathsf {x}}}$ and ${\displaystyle {\mathsf {p}}}$ satisfying the Heisenberg relation ${\displaystyle [{\mathsf {x}},{\mathsf {p}}]=i\hbar }$.
For the N-dimensional case, the propagator can be simply obtained by the product

${\displaystyle K({\vec {x}},{\vec {x}}';t)=\prod _{q=1}^{N}K(x_{q},x_{q}';t)~.}$

Relativistic propagators

In relativistic quantum mechanics and quantum field theory the propagators are Lorentz invariant. They give the amplitude for a particle to travel between two spacetime points.

Scalar propagator

In quantum field theory, the theory of a free (non-interacting) scalar field is a useful and simple example which serves to illustrate the concepts needed for more complicated theories. It describes spin zero particles. There are a number of possible propagators for free scalar field theory. We now describe the most common ones.

Position space

The position space propagators are Green's functions for the Klein–Gordon equation. This means they are functions G(x, y) which satisfy

${\displaystyle (\square _{x}+m^{2})G(x,y)=-\delta (x-y)}$

where:

• x, y are two points in Minkowski spacetime.
• ${\displaystyle \square _{x}={\tfrac {\partial ^{2}}{\partial t^{2}}}-\nabla ^{2}}$ is the d'Alembertian operator acting on the x coordinates.
• δ(x − y) is the Dirac delta-function.

(As typical in relativistic quantum field theory calculations, we use units where the speed of light, c, and Planck's reduced constant, ħ, are set to unity.)

We shall restrict attention to 4-dimensional Minkowski spacetime. We can perform a Fourier transform of the equation for the propagator, obtaining

${\displaystyle \left(-p^{2}+m^{2}\right)G(p)=-1.}$

This equation can be inverted in the sense of distributions noting that the equation xf(x)=1 has the solution, (see Sokhotski-Plemelj theorem)

${\displaystyle f(x)={\frac {1}{x\pm i\varepsilon }}={\frac {1}{x}}\mp i\pi \delta (x),}$

with ε implying the limit to zero. Below, we discuss the right choice of the sign arising from causality requirements.

The solution is

${\displaystyle G(x,y)={\frac {1}{(2\pi )^{4}}}\int d^{4}p\,{\frac {e^{-ip(x-y)}}{p^{2}-m^{2}\pm i\varepsilon }}~,}$

where

${\displaystyle p(x-y):=p_{0}(x^{0}-y^{0})-{\vec {p}}\cdot ({\vec {x}}-{\vec {y}})}$

is the 4-vector inner product.

The different choices for how to deform the integration contour in the above expression lead to various forms for the propagator. The choice of contour is usually phrased in terms of the ${\displaystyle p_{0}}$ integral.

The integrand then has two poles at

${\displaystyle p_{0}=\pm {\sqrt {{\vec {p}}^{2}+m^{2}}}}$

so different choices of how to avoid these lead to different propagators.

Causal propagators

Retarded propagator

A contour going clockwise over both poles gives the causal retarded propagator. This is zero if x-y is spacelike or if x ⁰< y ⁰ (i.e. if y is to the future of x).

This choice of contour is equivalent to calculating the limit,

${\displaystyle G_{\text{ret}}(x,y)=\lim _{\varepsilon \to 0}{\frac {1}{(2\pi )^{4}}}\int d^{4}p\,{\frac {e^{-ip(x-y)}}{(p_{0}+i\varepsilon )^{2}-{\vec {p}}^{2}-m^{2}}}=-{\frac {\Theta (x-y)}{2\pi }}\delta (\tau _{xy}^{2})+\Theta (x-y)\Theta (\tau _{xy}^{2}){\frac {mJ_{1}(m\tau _{xy})}{4\pi \tau _{xy}}}}$

Here

${\displaystyle \Theta (x):={\begin{cases}1&x\geq 0\\0&x<0 annotation="" cases="" end="">$

is the Heaviside step function and

${\displaystyle \tau _{xy}:={\sqrt {(x^{0}-y^{0})^{2}-({\vec {x}}-{\vec {y}})^{2}}}}$

is the proper time from x to y and ${\displaystyle J_{1}}$ is a Bessel function of the first kind. The expression ${\displaystyle y\prec x}$ means y causally precedes x which, for Minkowski spacetime, means

${\displaystyle y^{0}$ and ${\displaystyle \tau _{xy}^{2}\geq 0~.}$

This expression can be related to the vacuum expectation value of the commutator of the free scalar field operator,

${\displaystyle G_{\text{ret}}(x,y)=i\langle 0|\left[\Phi (x),\Phi (y)\right]|0\rangle \Theta (x^{0}-y^{0})}$

where

${\displaystyle \left[\Phi (x),\Phi (y)\right]:=\Phi (x)\Phi (y)-\Phi (y)\Phi (x)}$

is the commutator.

Advanced propagator

A contour going anti-clockwise under both poles gives the causal advanced propagator. This is zero if x-y is spacelike or if x ⁰> y ⁰ (i.e. if y is to the past of x).

This choice of contour is equivalent to calculating the limit

${\displaystyle G_{\text{adv}}(x,y)=\lim _{\varepsilon \to 0}{\frac {1}{(2\pi )^{4}}}\int d^{4}p\,{\frac {e^{-ip(x-y)}}{(p_{0}-i\varepsilon )^{2}-{\vec {p}}^{2}-m^{2}}}=-{\frac {\Theta (y-x)}{2\pi }}\delta (\tau _{xy}^{2})+\Theta (y-x)\Theta (\tau _{xy}^{2}){\frac {mJ_{1}(m\tau _{xy})}{4\pi \tau _{xy}}}}$

This expression can also be expressed in terms of the vacuum expectation value of the commutator of the free scalar field. In this case,

${\displaystyle G_{\text{adv}}(x,y)=-i\langle 0|\left[\Phi (x),\Phi (y)\right]|0\rangle \Theta (y^{0}-x^{0})~.}$

Feynman propagator

A contour going under the left pole and over the right pole gives the Feynman propagator.
This choice of contour is equivalent to calculating the limit^[5]

${\displaystyle G_{F}(x,y)=\lim _{\varepsilon \to 0}{\frac {1}{(2\pi )^{4}}}\int d^{4}p\,{\frac {e^{-ip(x-y)}}{p^{2}-m^{2}+i\varepsilon }}={\begin{cases}-{\frac {1}{4\pi }}\delta (s)+{\frac {m}{8\pi {\sqrt {s}}}}H_{1}^{(2)}(m{\sqrt {s}})&s\geq 0\\-{\frac {im}{4\pi ^{2}{\sqrt {-s}}}}K_{1}(m{\sqrt {-s}})&s<0 .="" annotation="" cases="" end="">$

Here

${\displaystyle s:=(x^{0}-y^{0})^{2}-({\vec {x}}-{\vec {y}})^{2},}$

where x and y are two points in Minkowski spacetime, and the dot in the exponent is a four-vector inner product. H₁⁽²⁾ is a Hankel function and K₁ is a modified Bessel function.

This expression can be derived directly from the field theory as the vacuum expectation value of the time-ordered product of the free scalar field, that is, the product always taken such that the time ordering of the spacetime points is the same,

${\displaystyle {\begin{aligned}G_{F}(x-y)&=-i\langle 0|T(\Phi (x)\Phi (y))|0\rangle \\[4pt]&=-i\left\langle 0|\left[\Theta (x^{0}-y^{0})\Phi (x)\Phi (y)+\Theta (y^{0}-x^{0})\Phi (y)\Phi (x)\right]|0\right\rangle .\end{aligned}}}$

This expression is Lorentz invariant, as long as the field operators commute with one another when the points x and y are separated by a spacelike interval.

The usual derivation is to insert a complete set of single-particle momentum states between the fields with Lorentz covariant normalization, and to then show that the Θ functions providing the causal time ordering may be obtained by a contour integral along the energy axis, if the integrand is as above (hence the infinitesimal imaginary part), to move the pole off the real line.

The propagator may also be derived using the path integral formulation of quantum theory.

Momentum space propagator

The Fourier transform of the position space propagators can be thought of as propagators in momentum space. These take a much simpler form than the position space propagators.

They are often written with an explicit ε term although this is understood to be a reminder about which integration contour is appropriate (see above). This ε term is included to incorporate boundary conditions and causality (see below).

For a 4-momentum p the causal and Feynman propagators in momentum space are:

${\displaystyle {\tilde {G}}_{\text{ret}}(p)={\frac {1}{(p_{0}+i\varepsilon )^{2}-{\vec {p}}^{2}-m^{2}}}}$

${\displaystyle {\tilde {G}}_{\text{adv}}(p)={\frac {1}{(p_{0}-i\varepsilon )^{2}-{\vec {p}}^{2}-m^{2}}}}$

${\displaystyle {\tilde {G}}_{F}(p)={\frac {1}{p^{2}-m^{2}+i\varepsilon }}.}$

For purposes of Feynman diagram calculations, it is usually convenient to write these with an additional overall factor of −i (conventions vary).

Faster than light?

The Feynman propagator has some properties that seem baffling at first. In particular, unlike the commutator, the propagator is nonzero outside of the light cone, though it falls off rapidly for spacelike intervals. Interpreted as an amplitude for particle motion, this translates to the virtual particle travelling faster than light. It is not immediately obvious how this can be reconciled with causality: can we use faster-than-light virtual particles to send faster-than-light messages?
The answer is no: while in classical mechanics the intervals along which particles and causal effects can travel are the same, this is no longer true in quantum field theory, where it is commutators that determine which operators can affect one another.

So what does the spacelike part of the propagator represent? In QFT the vacuum is an active participant, and particle numbers and field values are related by an uncertainty principle; field values are uncertain even for particle number zero. There is a nonzero probability amplitude to find a significant fluctuation in the vacuum value of the field Φ(x) if one measures it locally (or, to be more precise, if one measures an operator obtained by averaging the field over a small region). Furthermore, the dynamics of the fields tend to favor spatially correlated fluctuations to some extent. The nonzero time-ordered product for spacelike-separated fields then just measures the amplitude for a nonlocal correlation in these vacuum fluctuations, analogous to an EPR correlation. Indeed, the propagator is often called a two-point correlation function for the free field.

Since, by the postulates of quantum field theory, all observable operators commute with each other at spacelike separation, messages can no more be sent through these correlations than they can through any other EPR correlations; the correlations are in random variables.

Regarding virtual particles, the propagator at spacelike separation can be thought of as a means of calculating the amplitude for creating a virtual particle-antiparticle pair that eventually disappears into the vacuum, or for detecting a virtual pair emerging from the vacuum. In Feynman's language, such creation and annihilation processes are equivalent to a virtual particle wandering backward and forward through time, which can take it outside of the light cone. However, no signaling back in time is allowed.

Explanation using limits

This can be made clearer by writing the propagator in the following form for a massless photon,

${\displaystyle G_{F}^{\varepsilon }(x,y)={\frac {\varepsilon }{(x-y)^{2}+i\varepsilon ^{2}}}~.}$

This is the usual definition but normalised by a factor of ${\displaystyle \varepsilon }$. Then the rule is that one only takes the limit ${\displaystyle \varepsilon \rightarrow 0}$ at the end of a calculation.

One sees that

${\displaystyle G_{F}^{\varepsilon }(x,y)={\frac {1}{\varepsilon }}}$   if   ${\displaystyle (x-y)^{2}=0}$

and

${\displaystyle \lim _{\varepsilon \rightarrow 0}G_{F}^{\varepsilon }(x,y)=0}$   if   ${\displaystyle (x-y)^{2}\neq 0}$

Hence this means a single photon will always stay on the light cone. It is also shown that the total probability for a photon at any time must be normalised by the reciprocal of the following factor:

${\displaystyle \lim _{\varepsilon \rightarrow 0}\int \left|G_{F}^{\varepsilon }(0,x)\right|^{2}\,dx^{3}=\lim _{\varepsilon \rightarrow 0}\int {\frac {\varepsilon ^{2}}{({\mathbf {x} }^{2}-t^{2})^{2}+\varepsilon ^{4}}}\,dx^{3}=2\pi ^{2}|t|~.}$

We see that the parts outside the light cone usually are zero in the limit and only are important in Feynman diagrams.

Propagators in Feynman diagrams

The most common use of the propagator is in calculating probability amplitudes for particle interactions using Feynman diagrams. These calculations are usually carried out in momentum space. In general, the amplitude gets a factor of the propagator for every internal line, that is, every line that does not represent an incoming or outgoing particle in the initial or final state. It will also get a factor proportional to, and similar in form to, an interaction term in the theory's Lagrangian for every internal vertex where lines meet. These prescriptions are known as Feynman rules.

Internal lines correspond to virtual particles. Since the propagator does not vanish for combinations of energy and momentum disallowed by the classical equations of motion, we say that the virtual particles are allowed to be off shell. In fact, since the propagator is obtained by inverting the wave equation, in general, it will have singularities on the shell.

The energy carried by the particle in the propagator can even be negative. This can be interpreted simply as the case in which, instead of a particle going one way, its antiparticle is going the other way, and therefore carrying an opposing flow of positive energy. The propagator encompasses both possibilities. It does mean that one has to be careful about minus signs for the case of fermions, whose propagators are not even functions in the energy and momentum (see below).

Virtual particles conserve energy and momentum. However, since they can be off the shell, wherever the diagram contains a closed loop, the energies and momenta of the virtual particles participating in the loop will be partly unconstrained, since a change in a quantity for one particle in the loop can be balanced by an equal and opposite change in another. Therefore, every loop in a Feynman diagram requires an integral over a continuum of possible energies and momenta. In general, these integrals of products of propagators can diverge, a situation that must be handled by the process of renormalization.

Other theories

Spin ​¹⁄₂

If the particle possesses spin then its propagator is in general somewhat more complicated, as it will involve the particle's spin or polarization indices. The differential equation satisfied by the propagator for a spin ​¹⁄₂ particle is given by^[6]

${\displaystyle (i\not \nabla '-m)S_{F}(x',x)=I_{4}\delta ^{4}(x'-x),}$

where I₄ is the unit matrix in four dimensions, and employing the Feynman slash notation. This is the Dirac equation for a delta function source in spacetime. Using the momentum representation,

${\displaystyle S_{F}(x',x)=\int {\frac {d^{4}p}{(2\pi )^{4}}}\exp {\left[-ip\cdot (x'-x)\right]}{\tilde {S}}_{F}(p),}$

the equation becomes

${\displaystyle {\begin{aligned}&(i\not \nabla '-m)\int {\frac {d^{4}p}{(2\pi )^{4}}}{\tilde {S}}_{F}(p)\exp {\left[-ip\cdot (x'-x)\right]}\\[6pt]={}&\int {\frac {d^{4}p}{(2\pi )^{4}}}(\not p-m){\tilde {S}}_{F}(p)\exp {\left[-ip\cdot (x'-x)\right]}\\[6pt]={}&\int {\frac {d^{4}p}{(2\pi )^{4}}}I_{4}\exp {\left[-ip\cdot (x'-x)\right]}\\[6pt]={}&I_{4}\delta ^{4}(x'-x),\end{aligned}}}$

where on the right-hand side an integral representation of the four-dimensional delta function is used. Thus

${\displaystyle (\not p-mI_{4}){\tilde {S}}_{F}(p)=I_{4}.}$

By multiplying from the left with

${\displaystyle (\not p+m)}$

(dropping unit matrices from the notation) and using properties of the gamma matrices,

${\displaystyle {\begin{aligned}\not p\not p&={\frac {1}{2}}(\not p\not p+\not p\not p)\\[6pt]&={\frac {1}{2}}(\gamma _{\mu }p^{\mu }\gamma _{\nu }p^{\nu }+\gamma _{\nu }p^{\nu }\gamma _{\mu }p^{\mu })\\[6pt]&={\frac {1}{2}}(\gamma _{\mu }\gamma _{\nu }+\gamma _{\nu }\gamma _{\mu })p^{\mu }p^{\nu }\\[6pt]&=g_{\mu \nu }p^{\mu }p^{\nu }=p_{\nu }p^{\nu }=p^{2},\end{aligned}}}$

the momentum-space propagator used in Feynman diagrams for a Dirac field representing the electron in quantum electrodynamics is found to have form

${\displaystyle {\tilde {S}}_{F}(p)={\frac {(\not p+m)}{p^{2}-m^{2}+i\varepsilon }}={\frac {(\gamma ^{\mu }p_{\mu }+m)}{p^{2}-m^{2}+i\varepsilon }}.}$

The iε downstairs is a prescription for how to handle the poles in the complex p₀-plane. It automatically yields the Feynman contour of integration by shifting the poles appropriately. It is sometimes written

${\displaystyle {\tilde {S}}_{F}(p)={1 \over \gamma ^{\mu }p_{\mu }-m+i\varepsilon }={1 \over \not p-m+i\varepsilon }}$

for short. It should be remembered that this expression is just shorthand notation for (γ_μp^μ − m)⁻¹. "One over matrix" is otherwise nonsensical. In position space one has

${\displaystyle S_{F}(x-y)=\int {\frac {d^{4}p}{(2\pi )^{4}}}\,e^{-ip\cdot (x-y)}{\frac {\gamma ^{\mu }p_{\mu }+m}{p^{2}-m^{2}+i\varepsilon }}=\left({\frac {\gamma ^{\mu }(x-y)_{\mu }}{|x-y|^{5}}}+{\frac {m}{|x-y|^{3}}}\right)J_{1}(m|x-y|).}$

This is related to the Feynman propagator by

${\displaystyle S_{F}(x-y)=(i\not \partial +m)G_{F}(x-y)}$

where ${\displaystyle \not \partial :=\gamma ^{\mu }\partial _{\mu }}$.

Spin 1

The propagator for a gauge boson in a gauge theory depends on the choice of convention to fix the gauge. For the gauge used by Feynman and Stueckelberg, the propagator for a photon is

${\displaystyle {-ig^{\mu \nu } \over p^{2}+i\varepsilon }.}$

The propagator for a massive vector field can be derived from the Stueckelberg Lagrangian. The general form with gauge parameter λ reads

${\displaystyle {\frac {g_{\mu \nu }-{\frac {k_{\mu }k_{\nu }}{m^{2}}}}{k^{2}-m^{2}+i\varepsilon }}+{\frac {\frac {k_{\mu }k_{\nu }}{m^{2}}}{k^{2}-{\frac {m^{2}}{\lambda }}+i\varepsilon }}.}$

With this general form one obtains the propagator in unitary gauge for λ = 0, the propagator in Feynman or 't Hooft gauge for λ = 1 and in Landau or Lorenz gauge for λ = ∞. There are also other notations where the gauge parameter is the inverse of λ. The name of the propagator, however, refers to its final form and not necessarily to the value of the gauge parameter.

Unitary gauge:

${\displaystyle {\frac {g_{\mu \nu }-{\frac {k_{\mu }k_{\nu }}{m^{2}}}}{k^{2}-m^{2}+i\varepsilon }}.}$

Feynman ('t Hooft) gauge:

${\displaystyle {\frac {g_{\mu \nu }}{k^{2}-m^{2}+i\varepsilon }}.}$

Landau (Lorenz) gauge:

${\displaystyle {\frac {g_{\mu \nu }-{\frac {k_{\mu }k_{\nu }}{k^{2}}}}{k^{2}-m^{2}+i\varepsilon }}.}$

Graviton propagator

The graviton propagator for Minkowski space in general relativity is

${\displaystyle G={\frac {{\mathcal {P}}^{2}}{k^{2}}}-{\frac {{\mathcal {P}}_{s}^{0}}{2k^{2}}},}$

where ${\displaystyle {\mathcal {P}}^{2}}$ is the transverse and traceless spin-2 projection operator and ${\displaystyle {\mathcal {P}}_{s}^{0}}$ is a spin-0 scalar multiplet. The graviton propagator for (Anti) de Sitter space is

${\displaystyle G={\frac {{\mathcal {P}}^{2}}{k^{2}+2H^{2}}}-{\frac {{\mathcal {P}}_{s}^{0}}{2(k^{2}-4H^{2})}},}$

where ${\displaystyle H}$ is the Hubble constant. Note that upon taking the limit ${\displaystyle H\to 0}$, the AdS propagator reduces to the Minkowski propagator.^[7]

Related singular functions

The scalar propagators are Green's functions for the Klein–Gordon equation. There are related singular functions which are important in quantum field theory. We follow the notation in Bjorken and Drell.^[8] See also Bogolyubov and Shirkov (Appendix A). These functions are most simply defined in terms of the vacuum expectation value of products of field operators.

Solutions to the Klein–Gordon equation

Pauli–Jordan function

The commutator of two scalar field operators defines the Pauli–Jordan function ${\displaystyle \Delta (x-y)}$ by^[8]

${\displaystyle \langle 0|\left[\Phi (x),\Phi (y)\right]|0\rangle =i\,\Delta (x-y)}$

with

${\displaystyle \,\Delta (x-y)=G_{\text{adv}}(x-y)-G_{\text{ret}}(x-y)}$

This satisfies

${\displaystyle \Delta (x-y)=-\Delta (y-x)}$

and is zero if ${\displaystyle (x-y)^{2}<0 annotation="">$.

Positive and negative frequency parts (cut propagators)

We can define the positive and negative frequency parts of ${\displaystyle \Delta (x-y)}$, sometimes called cut propagators, in a relativistically invariant way.

This allows us to define the positive frequency part:

${\displaystyle \Delta _{+}(x-y)=\langle 0|\Phi (x)\Phi (y)|0\rangle ,}$

and the negative frequency part:

${\displaystyle \Delta _{-}(x-y)=\langle 0|\Phi (y)\Phi (x)|0\rangle .}$

These satisfy^[8]

${\displaystyle \,i\Delta =\Delta _{+}-\Delta _{-}}$

and

${\displaystyle (\Box _{x}+m^{2})\Delta _{\pm }(x-y)=0.}$

Auxiliary function

The anti-commutator of two scalar field operators defines ${\displaystyle \Delta _{1}(x-y)}$ function by

${\displaystyle \langle 0|\left\{\Phi (x),\Phi (y)\right\}|0\rangle =\Delta _{1}(x-y)}$

with

${\displaystyle \,\Delta _{1}(x-y)=\Delta _{+}(x-y)+\Delta _{-}(x-y).}$

This satisfies ${\displaystyle \,\Delta _{1}(x-y)=\Delta _{1}(y-x).}$

Green's functions for the Klein–Gordon equation

The retarded, advanced and Feynman propagators defined above are all Green's functions for the Klein–Gordon equation.

They are related to the singular functions by^[8]

${\displaystyle G_{\text{ret}}(x-y)=-\Delta (x-y)\Theta (x_{0}-y_{0})}$

${\displaystyle G_{\text{adv}}(x-y)=\Delta (x-y)\Theta (y_{0}-x_{0})}$

${\displaystyle 2G_{F}(x-y)=-i\,\Delta _{1}(x-y)+\varepsilon (x_{0}-y_{0})\,\Delta (x-y)}$

where

${\displaystyle \,\varepsilon (x_{0}-y_{0})=2\Theta (x_{0}-y_{0})-1.}$

A noninvasive method for deep-brain stimulation for brain disorders

Could make deep-brain stimulation less risky, less expensive, and more available to patients and researchers

June 11, 2017
Original link:  http://www.kurzweilai.net/a-noninvasive-method-for-deep-brain-stimulation-for-brain-disorders

External electrical waves excite an area in the mouse hippocampus, shown in bright green. (credit: Nir Grossman, Ph.D., Suhasa B. Kodandaramaiah, Ph.D., and Andrii Rudenko, Ph.D.)

MIT researchers and associates have come up with a breakthrough method of remotely stimulating regions deep within the brain, replacing the invasive surgery now required for implanting electrodes for Parkinson’s and other brain disorders.

The new method could make deep-brain stimulation for brain disorders less expensive, more accessible to patients, and less risky (avoiding brain hemorrhage and infection).

Working with mice, the researchers applied two high-frequency electrical currents at two slightly different frequencies (E1 and E2 in the diagram below), attaching electrodes (similar those used with an EEG brain machine) to the surface of the skull.

A new noninvasive method for deep-brain stimulation (credit: Grossman et al./Cell)

At these higher brain frequencies, the currents have no effect on brain tissues. But where the currents converge deep in the brain, they interfere with one another in such a way that they generate low-frequency current (corresponding to the red envelope in the diagram) inside neurons, thus stimulating neural electrical activity.

The researchers named this method “temporal interference stimulation” (that is, interference between pulses in the two currents at two slightly different times — generating the difference frequency).* For the experimental setup shown in the diagram above, the E1 current was 1kHz (1,000 Hz), which mixed with a 1.04kHz E2 current. That generated a current with a 40Hz “delta f” difference frequency — a frequency that can stimulate neural activity in the brain. (The researchers found no harmful effects in any part of the mouse brain.)

“Traditional deep-brain stimulation requires opening the skull and implanting an electrode, which can have complications,” explains Ed Boyden, an associate professor of biological engineering and brain and cognitive sciences at MIT, and the senior author of the study, which appears in the June 1, 2017 issue of the journal Cell. Also, “only a small number of people can do this kind of neurosurgery.”

Custom-designed, targeted deep-brain stimulation

If this new method is perfected and clinically tested, neurologists could control the size and location of the exact tissue that receives the electrical stimulation for each patient, by selecting the frequency of the currents and the number and location of the electrodes, according to the researchers.

Neurologists could also steer the location of deep-brain stimulation in real time, without moving the electrodes, by simply altering the currents. In this way, deep targets could be stimulated for conditions such as Parkinson’s, epilepsy, depression, and obsessive-compulsive disorder — without affecting surrounding brain structures.

The researchers are also exploring the possibility of using this method to experimentally treat other brain conditions, such as autism, and for basic science investigations.

Co-author Li-Huei Tsai, director of MIT’s Picower Institute for Learning and Memory, and researchers in her lab tested this technique in mice and found that they could stimulate small regions deep within the brain, including the hippocampus. But they were also able to shift the site of stimulation, allowing them to activate different parts of the motor cortex and prompt the mice to move their limbs, ears, or whiskers.

“We showed that we can very precisely target a brain region to elicit not just neuronal activation but behavioral responses,” says Tsai.

Last year, Tsai showed (open access) that using light to visually induce brain waves of a particular frequency could substantially reduce the beta amyloid plaques seen in Alzheimer’s disease, in the brains of mice. She now plans to explore whether this new type of electrical stimulation could offer a new way to generate the same type of beneficial brain waves.

This new method is also an alternative to other brain-stimulation methods.

Transcranial magnetic stimulation (TMS), which is FDA-approved for treating depression and to study the basic science of cognition, emotion, sensation, and movement, can stimulate deep brain structures but can result in surface regions being strongly stimulated, according to the researchers.

Transcranial ultrasound and expression of heat-sensitive receptors and injection of thermomagnetic nanoparticles have been proposed, “but the unknown mechanism of action … and the need to genetically manipulate the brain, respectively, may limit their immediate use in humans,” the researchers note in the paper.

The MIT researchers collaborated with investigators at Beth Israel Deaconess Medical Center (BIDMC), the IT’IS Foundation, Harvard Medical School, and ETH Zurich.

The research was funded in part by the Wellcome Trust, a National Institutes of Health Director’s Pioneer Award, an NIH Director’s Transformative Research Award, the New York Stem Cell Foundation Robertson Investigator Award, the MIT Center for Brains, Minds, and Machines, Jeremy and Joyce Wertheimer, Google, a National Science Foundation Career Award, the MIT Synthetic Intelligence Project, and Harvard Catalyst: The Harvard Clinical and Translational Science Center.

* Similar to a radio-frequency or audio “beat frequency.”

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Abstract of Noninvasive Deep Brain Stimulation via Temporally Interfering Electric Fields

We report a noninvasive strategy for electrically stimulating neurons at depth. By delivering to the brain multiple electric fields at frequencies too high to recruit neural firing, but which differ by a frequency within the dynamic range of neural firing, we can electrically stimulate neurons throughout a region where interference between the multiple fields results in a prominent electric field envelope modulated at the difference frequency. We validated this temporal interference (TI) concept via modeling and physics experiments, and verified that neurons in the living mouse brain could follow the electric field envelope. We demonstrate the utility of TI stimulation by stimulating neurons in the hippocampus of living mice without recruiting neurons of the overlying cortex. Finally, we show that by altering the currents delivered to a set of immobile electrodes, we can steerably evoke different motor patterns in living mice.

References:

• Grossman, Nir et al. Noninvasive Deep Brain Stimulation via Temporally Interfering Electric Fields. Cell , Volume 169 , Issue 6 , 1029 - 1041.e16. DOI: 10.1016/j.cell.2017.05.024