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Friday, June 29, 2018

Atmosphere of Venus

From Wikipedia, the free encyclopedia

Venus
Cloud structure in Venus's atmosphere in 1979,
revealed by ultraviolet observations from Pioneer Venus Orbiter
General information[1]
Height 250 km (160 mi)
Average surface pressure 93 bar or 9.3 MPa
Mass 4.8 × 1020 kg
Composition[1][2]
Carbon dioxide 96.5 %
Nitrogen 3.5 %
Sulfur dioxide 150 ppm
Argon 70 ppm
Water vapour 20 ppm
Carbon monoxide 17 ppm
Helium 12 ppm
Neon 7 ppm
Hydrogen chloride 0.1–0.6 ppm
Hydrogen fluoride 0.001–0.005 ppm

The atmosphere of Venus is the layer of gases surrounding Venus. It is composed primarily of carbon dioxide and is much denser and hotter than that of Earth. The temperature at the surface is 740 K (467 °C, 872 °F), and the pressure is 93 bar (9.3 MPa), roughly the pressure found 900 m (3,000 ft) underwater on Earth.[1] The Venusian atmosphere supports opaque clouds made of sulfuric acid, making optical Earth-based and orbital observation of the surface impossible. Information about the topography has been obtained exclusively by radar imaging.[1] Aside from carbon dioxide, the other main component is nitrogen. Other chemical compounds are present only in trace amounts.

Aside from the very surface layers, the atmosphere is in a state of vigorous circulation.[3] The upper layer of troposphere exhibits a phenomenon of super-rotation, in which the atmosphere circles the planet in just four Earth days, much faster than the planet's sidereal day of 243 days. The winds supporting super-rotation blow at a speed of 100 m/s (~360 km/h or 220 mph)[3] or more. Winds move at up to 60 times the speed of the planet's rotation, while Earth's fastest winds are only 10% to 20% rotation speed.[4] On the other hand, the wind speed becomes increasingly slower as the elevation from the surface decreases, with the breeze barely reaching the speed of 10 km/h (2.8 m/s) on the surface.[5] Near the poles are anticyclonic structures called polar vortices. Each vortex is double-eyed and shows a characteristic S-shaped pattern of clouds.[6] Above there is an intermediate layer of mesosphere which separates the troposphere from the thermosphere.[3][2] The thermosphere is also characterized by strong circulation, but very different in its nature - the gases heated and partially ionized by sunlight in the sunlit hemisphere migrate to the dark hemisphere where they recombine and downwell.[2]

Unlike Earth, Venus lacks a magnetic field. Its ionosphere separates the atmosphere from outer space and the solar wind. This ionised layer excludes the solar magnetic field, giving Venus a distinct magnetic environment. This is considered Venus's induced magnetosphere. Lighter gases, including water vapour, are continuously blown away by the solar wind through the induced magnetotail.[3] It is speculated that the atmosphere of Venus up to around 4 billion years ago was more like that of the Earth with liquid water on the surface. A runaway greenhouse effect may have been caused by the evaporation of the surface water and subsequent rise of the levels of other greenhouse gases.[7][8]

Despite the harsh conditions on the surface, the atmospheric pressure and temperature at about 50 km to 65 km above the surface of the planet is nearly the same as that of the Earth, making its upper atmosphere the most Earth-like area in the Solar System, even more so than the surface of Mars. Due to the similarity in pressure and temperature and the fact that breathable air (21% oxygen, 78% nitrogen) is a lifting gas on Venus in the same way that helium is a lifting gas on Earth, the upper atmosphere has been proposed as a location for both exploration and colonization.[9]

On January 29, 2013, ESA scientists reported that the ionosphere of the planet Venus streams outwards in a manner similar to "the ion tail seen streaming from a comet under similar conditions."

History

Mikhail Lomonosov was the first person to hypothesize the existence of an atmosphere on Venus based on his observation of the transit of Venus of 1761 in a small observatory near his house in Saint Petersburg, Russia.[12]

Structure and composition

Composition

Composition of the atmosphere of Venus. The chart on the right is an expanded view of the trace elements that all together do not even make up a tenth of a percent.

The atmosphere of Venus is composed of 96.5% carbon dioxide, 3.5% nitrogen, and traces of other gases, most notably sulfur dioxide.[13] The amount of nitrogen in the atmosphere is relatively small compared to the amount of carbon dioxide, but because the atmosphere is so much thicker than that on Earth, its total nitrogen content is roughly four times higher than Earth's, even though on Earth nitrogen makes up about 78% of the atmosphere.[1][14]

The atmosphere contains a range of interesting compounds in small quantities, including some based on hydrogen, such as hydrogen chloride (HCl) and hydrogen fluoride (HF). There is carbon monoxide, water vapour and atomic oxygen as well.[2][3] Hydrogen is in relatively short supply in the Venusian atmosphere. A large amount of the planet's hydrogen is theorised to have been lost to space,[15] with the remainder being mostly bound up in sulfuric acid (H2SO4) and hydrogen sulfide (H2S). The loss of significant amounts of hydrogen is proven by a very high D–H ratio measured in the Venusian atmosphere.[3] The ratio is about 0.015–0.025, which is 100–150 times higher than the terrestrial value of 1.6×10−4.[2][16] According to some measurements, in the upper atmosphere of Venus D/H ratio is 1.5 higher than in the bulk atmosphere.[2]

Troposphere

Comparison of Atmosphere Compositions – Venus, Mars, Earth (past and present).

The atmosphere is divided into a number of sections depending on altitude. The densest part of the atmosphere, the troposphere, begins at the surface and extends upwards to 65 km. At the furnace-like surface the winds are slow,[1] but at the top of the troposphere the temperature and pressure reaches Earth-like levels and clouds pick up speed to 100 m/s.[3][17]

1761 drawing by Mikhail Lomonosov in his work on discovery of atmosphere of Venus

The atmospheric pressure at the surface of Venus is about 92 times that of the Earth, similar to the pressure found 900 m (3,000 ft) below the surface of the ocean. The atmosphere has a mass of 4.8×1020 kg, about 93 times the mass of the Earth's total atmosphere. The density of the air at the surface is 67 kg/m3, which is 6.5% that of liquid water on Earth.[1] The pressure found on Venus's surface is high enough that the carbon dioxide is technically no longer a gas, but a supercritical fluid. This supercritical carbon dioxide forms a kind of sea that covers the entire surface of Venus. This sea of supercritical carbon dioxide transfers heat very efficiently, buffering the temperature changes between night and day (which last 56 terrestrial days).[18]

The large amount of CO2 in the atmosphere together with water vapour and sulfur dioxide create a strong greenhouse effect, trapping solar energy and raising the surface temperature to around 740 K (467 °C),[14] hotter than any other planet in the Solar System, even that of Mercury despite being located farther out from the Sun and receiving only 25% of the solar energy (per unit area) Mercury does.[citation needed] The average temperature on the surface is above the melting points of lead (600 K, 327 °C), tin (505 K, 232 °C), and zinc (693 K, 420 °C). The thick troposphere also makes the difference in temperature between the day and night side small, even though the slow retrograde rotation of the planet causes a single solar day to last 116.5 Earth days. The surface of Venus spends 58.3 days in darkness before the sun rises again behind the clouds.[1]
Atmosphere [19]
Venusatmosphere.svg
Height
(km)
Temp.
(°C)
Atmospheric
pressure
(atm)
0 462 92.10
5 424 66.65
10 385 47.39
15 348 33.04
20 306 22.52
25 264 14.93
30 222 9.851
35 180 5.917
40 143 3.501
45 110 1.979
50 75 1.066
55 27 0.5314
60 −10 0.2357
65 −30 0.09765
70 −43 0.03690
80 −76 0.004760
90 −104 0.0003736
100 −112 0.00002660






































The troposphere on Venus contains 99% of the atmosphere by mass. Ninety percent of the atmosphere of Venus is within 28 km of the surface; by comparison, 90% of the atmosphere of Earth is within 10 km of the surface. At a height of 50 km the atmospheric pressure is approximately equal to that at the surface of Earth.[20] On the night side of Venus clouds can still be found at 80 km above the surface.[21]

The altitude of the troposphere most similar to Earth is near the tropopause—the boundary between troposphere and mesosphere. It is located slightly above 50 km.[17] According to measurements by the Magellan and Venus Express probes, the altitude from 52.5 to 54 km has a temperature between 293 K (20 °C) and 310 K (37 °C), and the altitude at 49.5 km above the surface is where the pressure becomes the same as Earth at sea level.[17][22] As manned ships sent to Venus would be able to compensate for differences in temperature to a certain extent, anywhere from about 50 to 54 km or so above the surface would be the easiest altitude in which to base an exploration or colony, where the temperature would be in the crucial "liquid water" range of 273 K (0 °C) to 323 K (50 °C) and the air pressure the same as habitable regions of Earth.[9][23] As CO2 is heavier than air, the colony's air (nitrogen and oxygen) could keep the structure floating at that altitude like a dirigible.

Circulation

The circulation in Venus's troposphere follows the so-called cyclostrophic approximation.[3] Its windspeeds are roughly determined by the balance of the pressure gradient and centrifugal forces in almost purely zonal flow. In contrast, the circulation in the Earth's atmosphere is governed by the geostrophic balance.[3] Venus's windspeeds can be directly measured only in the upper troposphere (tropopause), between 60–70 km, altitude, which corresponds to the upper cloud deck.[24] The cloud motion is usually observed in the ultraviolet part of the spectrum, where the contrast between clouds is the highest.[24] The linear wind speeds at this level are about 100 ± 10 m/s at lower than 50° latitude. They are retrograde in the sense that they blow in the direction of the retrograde rotation of the planet.[24] The winds quickly decrease towards the higher latitudes, eventually reaching zero at the poles. Such strong cloud-top winds cause a phenomenon known as the super-rotation of the atmosphere.[3] In other words, these high-speed winds circle the whole planet faster than the planet itself rotates.[23] The super-rotation on Venus is differential, which means that the equatorial troposphere super-rotates more slowly than the troposphere at the midlatitudes.[24] The winds also have a strong vertical gradient. They decline deep in the troposphere with the rate of 3 m/s per km.[3] The winds near the surface of Venus are much slower than that on Earth. They actually move at only a few kilometres per hour (generally less than 2 m/s and with an average of 0.3 to 1.0 m/s), but due to the high density of the atmosphere at the surface, this is still enough to transport dust and small stones across the surface, much like a slow-moving current of water.[1][25]

Meridional (north–south) component of the atmospheric circulation in the atmosphere of Venus. Note that the meridional circulation is much lower than the zonal circulation, which transports heat between the day and night sides of the planet

All winds on Venus are ultimately driven by convection.[3] Hot air rises in the equatorial zone, where solar heating is concentrated, and flows to the poles. Such an almost-planetwide overturning of the troposphere is called Hadley circulation.[3] However, the meridional air motions are much slower than zonal winds. The poleward limit of the planet wide Hadley cell on Venus is near ±60° latitudes.[3] Here air starts to descend and returns to the equator below the clouds. This interpretation is supported by the distribution of the carbon monoxide, which is also concentrated in the vicinity of ±60° latitudes.[3] Poleward of the Hadley cell a different pattern of circulation is observed. In the latitude range 60°–70° cold polar collars exist.[3][6] They are characterised by temperatures about 30–40 K lower than in the upper troposphere at nearby latitudes.[6] The lower temperature is probably caused by the upwelling of the air in them and by the resulting adiabatic cooling.[6] Such an interpretation is supported by the denser and higher clouds in the collars. The clouds lie at 70–72 km altitude in the collars—about 5 km higher than at the poles and low latitudes.[3] A connection may exist between the cold collars and high speed midlatitude jets in which winds blow as fast as 140 m/s. Such jets are a natural consequence of the Hadley–type circulation and should exist on Venus between 55–60° latitude.[24]

Odd structures known as polar vortices lie within the cold polar collars.[3] They are giant hurricane-like storms four times larger than their terrestrial analogs. Each vortex has two "eyes"—the centres of rotation, which are connected by distinct S-shaped cloud structures. Such double eyed structures are also called polar dipoles.[6] Vortices rotate with the period of about 3 days in the direction of general super-rotation of the atmosphere.[6] The linear wind speeds are 35–50 m/s near their outer edges and zero at the poles.[6] The temperature at the cloud-tops in the each polar vortex is much higher than in the nearby polar collars reaching 250 K (−23 °C).[6] The conventional interpretation of the polar vortices is that they are anticyclones with downwelling in the centre and upwelling in the cold polar collars.[6] This type of circulation resembles a winter polar anticyclonic vortex on Earth, especially the one found over Antarctica. The observations in the various infrared atmospheric windows indicate that the anticyclonic circulation observed near the poles penetrates as deep as to 50 km altitude, i.e. to the base of the clouds.[6] The polar upper troposphere and mesosphere are extremely dynamic; large bright clouds may appear and disappear over the space of a few hours. One such event was observed by Venus Express between 9 and 13 January 2007, when the south polar region became brighter by 30%.[24] This event was probably caused by an injection of sulfur dioxide into the mesosphere, which then condensed forming a bright haze.[24] The two eyes in the vortices have yet to be explained.[26]

False colour near infrared (2.3 μm) image of the deep atmosphere of Venus obtained by Galileo. The dark spots are clouds silhouetted against the very hot lower atmosphere emitting thermal infrared radiation.

The first vortex on Venus was discovered at the north pole by the Pioneer Venus mission in 1978.[27] A discovery of the second large 'double-eyed' vortex at the south pole of Venus was made in the summer of 2006 by Venus Express, which came with no surprise.[26]

Images from the Akatsuki orbiter revealed something similar to jet stream winds in the low and middle cloud region, which extends from 45 to 60 kilometers in altitude. The wind speed maximized near the equator. In September 2017 JAXA scientists named this phenomenon 'Venusian equatorial jet'.[28]

Upper atmosphere and ionosphere

The mesosphere of Venus extends from 65 km to 120 km in height, and the thermosphere begins at approximately 120 km, eventually reaching the upper limit of the atmosphere (exosphere) at about 220 to 350 km.[17] The exosphere is the altitude at which the atmosphere becomes collisionless.

The mesosphere of Venus can be divided into two layers: the lower one between 62–73 km[29] and the upper one between 73–95 km.[17] In the first layer the temperature is nearly constant at 230 K (−43 °C). This layer coincides with the upper cloud deck. In the second layer temperature starts to decrease again reaching about 165 K (−108 °C) at the altitude of 95 km, where mesopause begins.[17] It is the coldest part of the Venusian dayside atmosphere.[2] In the dayside mesopause, which serves as a boundary between the mesophere and thermosphere and is located between 95–120 km, temperature increases to a constant—about 300–400 K (27–127 °C)—value prevalent in the thermosphere.[2] In contrast, the nightside Venusian thermosphere is the coldest place on Venus with temperature as low as 100 K (−173 °C). It is even called a cryosphere.[2]

The circulation patterns in the upper mesosphere and thermosphere of Venus are completely different from those in the lower atmosphere.[2] At altitudes 90–150 km the Venusian air moves from the dayside to nightside of the planet, with upwelling over sunlit hemisphere and downwelling over dark hemisphere. The downwelling over the nightside causes adiabatic heating of the air, which forms a warm layer in the nightside mesosphere at the altitudes 90–120 km.[3][2] The temperature of this layer—230 K (−43 °C) is far higher than the typical temperature found in the nightside thermosphere—100 K (−173 °C).[2] The air circulated from the dayside also carries oxygen atoms, which after recombination form excited molecules of oxygen in the long-lived singlet state (1Δg), which then relax and emit infrared radiation at the wavelength 1.27 μm. This radiation from the altitude range 90–100 km is often observed from the ground and spacecraft.[30] The nightside upper mesosphere and thermosphere of Venus is also the source of non-local thermodynamic equilibrium emissions of CO2 and nitric oxide molecules, which are responsible for the low temperature of the nightside thermosphere.[30]

The Venus Express probe has shown through stellar occultation that the atmospheric haze extends much further up on the night side than the day side. On the day side the cloud deck has a thickness of 20 km and extends up to about 65 km, whereas on the night side the cloud deck in the form of a thick haze reaches up to 90 km in altitude—well into mesosphere, continuing even further to 105 km as a more transparent haze.[21] In 2011, the spacecraft discovered that Venus has a thin ozone layer at an altitude of 100 km.[31]

Venus has an extended ionosphere located at altitudes 120–300 km.[17] The ionosphere almost coincides with the thermosphere. The high levels of the ionization are maintained only over the dayside of the planet. Over the nightside the concentration of the electrons is almost zero.[17] The ionosphere of Venus consists of three layers: v1 between 120 and 130 km, v2 between 140 and 160 km and v3 between 200 and 250 km.[17] There may be an additional layer near 180 km. The maximum electron volume density (number of electrons in a unit of volume) 3×1011 m−3 is reached in the v2 layer near the subsolar point.[17] The upper boundary of the ionosphere—ionopause is located at altitudes 220–375 km and separates the plasma of the planetary origin from that of the induced magnetosphere.[32][33] The main ionic species in the v1 and v2 layers is O2+ ion, whereas the v3 layer consists of O+ ions.[17] The ionospheric plasma is observed to be in motion; solar photoionization on the dayside, and ion recombination on the nightside, are the processes mainly responsible for accelerating the plasma to the observed velocities. The plasma flow appears to be sufficient to maintain the nightside ionosphere at or near the observed median level of ion densities.[34]

Induced magnetosphere

Venus interacts with the solar wind. Components of the induced magnetosphere are shown.

Venus is known not to have a magnetic field.[32][33] The reason for its absence is not clear, but is probably related to the planet's slow rotation or the lack of convection in the mantle. Venus only has an induced magnetosphere formed by the Sun's magnetic field carried by the solar wind.[32] This process can be understood as the field lines wrapping around an obstacle—Venus in this case. The induced magnetosphere of Venus has a bow shock, magnetosheath, magnetopause and magnetotail with the current sheet.[32][33]

At the subsolar point the bow shock stands 1900 km (0.3 Rv, where Rv is the radius of Venus) above the surface of Venus. This distance was measured in 2007 near the solar activity minimum.[33] Near the solar activity maximum it can be several times further from the planet.[32] The magnetopause is located at the altitude of 300 km.[33] The upper boundary of the ionosphere (ionopause) is near 250 km. Between the magnetopause and ionopause there exists a magnetic barrier—a local enhancement of the magnetic field, which prevents solar plasma from penetrating deeper into the Venusian atmosphere, at least near solar activity minimum. The magnetic field in the barrier reaches up to 40 nT.[33] The magnetotail continues up to ten radii from the planet. It is the most active part of the Venusian magnetosphere. There are reconnection events and particle acceleration in the tail. The energies of electrons and ions in the magnetotail are around 100 eV and 1000 eV respectively.[35]

Due to the lack of the intrinsic magnetic field on Venus, the solar wind penetrates relatively deep into the planetary exosphere and causes substantial atmosphere loss.[36] The loss happens mainly via the magnetotail. Currently the main ion types being lost are O+, H+ and He+. The ratio of hydrogen to oxygen losses is around 2 (i.e. almost stoichiometric) indicating the ongoing loss of water.[35]

Clouds

Venusian clouds are thick and are composed mainly (75-96%) of sulfuric acid droplets.[37] These clouds obscure the surface of Venus from optical imaging, and reflect about 75%[38] of the sunlight that falls on them.[1] The geometric albedo, a common measure of reflectivity, is the highest of any planet in the Solar System. This high reflectivity potentially enables any probe exploring the cloud tops sufficient solar energy such that solar cells can be fitted anywhere on the craft.[39] The density of the clouds is highly variable with the densest layer at about 48.5 km, reaching 0.1 g/m3 similar to the lower range of cumulonimbus storm clouds on Earth.[40]

The cloud cover is such that typical surface light levels are similar to a partly cloudy day on Earth, around 5000–10000 lux. The equivalent visibility is about three kilometers, but this will likely vary with the wind conditions. Little to no solar energy could conceivably be collected by solar panels on a surface probe. In fact, due to the thick, highly reflective cloud cover, the total solar energy received by the surface of the planet is less than that of the Earth.

Photograph taken by the unmanned Galileo spaceprobe en route to Jupiter in 1990 during a Venus flyby. Smaller-scale cloud features have been emphasized and a bluish hue has been applied to show that it was taken through a violet filter.

Sulfuric acid is produced in the upper atmosphere by the Sun's photochemical action on carbon dioxide, sulfur dioxide, and water vapour.[41] Ultraviolet photons of wavelengths less than 169 nm can photodissociate carbon dioxide into carbon monoxide and atomic oxygen. Atomic oxygen is highly reactive; when it reacts with sulfur dioxide, a trace component of the Venusian atmosphere, the result is sulfur trioxide, which can combine with water vapour, another trace component of Venus's atmosphere, to yield sulfuric acid.[42]
CO2CO + O
SO2 + OSO3
2SO3 + 4H2O → 2H2SO4·H2O
Surface level humidity is less than 0.1%.[43] Venus's sulfuric acid rain never reaches the ground, but is evaporated by the heat before reaching the surface in a phenomenon known as virga.[44] It is theorized that early volcanic activity released sulfur into the atmosphere and the high temperatures prevented it from being trapped into solid compounds on the surface as it was on the Earth.[45]

In 2009 a prominent bright spot in the atmosphere was noted by an amateur astronomer and photographed by Venus Express. Its cause is currently unknown, with surface volcanism advanced as a possible explanation.[46]

Lightning

The clouds of Venus are capable of producing lightning much like the clouds on Earth.[47] The existence of lightning had been controversial outside of the former Soviet Union since the first suspected bursts were detected by the Soviet Venera probes. However, in 2006–2007 Venus Express was reported to detect whistler mode waves, which were attributed to lightning. Their intermittent appearance indicates a pattern associated with weather activity. The lightning rate is at least half of that on Earth.[47]

The sulfuric acid droplets can be highly electrically charged, and so they offer the potential for lightning.[41] Venus' small induced magnetosphere provides negligible protection to the atmosphere against cosmic radiation. This radiation may result in cloud-to-cloud lightning discharges.[48]

Throughout the 1980s, it was thought that the cause of the night-side glow ("ashen glow") on Venus was lightning.[49] The Soviet Venera 9 and 10 orbiters obtained optical and electromagnetic evidence of lightning on Venus.[50][51] Also, the Pioneer Venus Orbiter recorded visible airglow at Venus in 1978 strong enough to saturate its star sensor.[50] The European Space Agency's Venus Express in 2007 detected whistler waves further confirming the occurrence of lightning on Venus.[52][53]

Possibility of life

Due to the harsh conditions on the surface, little of the planet has been explored; in addition to the fact that life as currently understood may not necessarily be the same in other parts of the universe, the extent of the tenacity of life on Earth itself has not yet been shown. Creatures known as extremophiles exist on Earth, preferring extreme habitats. Thermophiles and hyperthermophiles thrive at temperatures reaching above the boiling point of water, acidophiles thrive at a pH level of 3 or below, polyextremophiles can survive a varied number of extreme conditions, and many other types of extremophiles exist on Earth.[54]
The surface temperature of Venus (over 450 °C) is far beyond the extremophile range, which extends only tens of degrees beyond 100 °C. However, the lower temperature of the cloud tops means that life could plausibly exist. It has been proposed that life on Venus could exist there, the same way that bacteria have been found living and reproducing in clouds on Earth.[55] Any such bacteria living in the cloud tops, however, would have to be hyper-acidiphilic, due to the concentrated sulfuric acid environment. Microbes in the thick, cloudy atmosphere could be protected from solar radiation by the sulfur compounds in the air.[54] The solar wind may provide a mechanism for the transfer of such microbiota from Venus to Earth.[56]

The Venusian atmosphere has been found to be sufficiently out of equilibrium as to require further investigation.[54] Analysis of data from the Venera, Pioneer, and Magellan missions has found the chemicals hydrogen sulfide (H2S) and sulfur dioxide (SO2) together in the upper atmosphere, as well as carbonyl sulfide (OCS). The first two gases react with each other, implying that something must produce them. Carbonyl sulfide is difficult to produce inorganically, but it is present in the Venusian atmosphere.[55] However, the planet's volcanism could explain the presence of carbonyl sulfide.[55] In addition, one of the early Venera probes detected large amounts of toxic chlorine just below the Venusian cloud deck.[57]

It has been proposed that microbes at this level could be soaking up ultraviolet light from the Sun as a source of energy, which could be a possible explanation for dark patches seen on UV images of the planet.[58][59] Large, non-spherical cloud particles have also been detected in the cloud decks.[citation needed] In 2012, the abundance and vertical distribution of these unknown ultraviolet absorbers in the Venusian atmosphere have been investigated from analysis of Venus Monitoring Camera images,[60] but their composition is still unknown.[54] In 2016, disulfur dioxide was identified as a possible candidate for causing the so far unknown UV absorption of the Venusian atmosphere.[61]

Evolution

Through studies of the present cloud structure and geology of the surface, combined with the fact that the luminosity of the Sun has increased by 25% since around 3.8 billion years ago,[62] it is thought that the early environment of Venus was more like that of Earth with liquid water on the surface. At some point in the evolution of Venus, a runaway greenhouse effect occurred, leading to the current greenhouse-dominated atmosphere. The timing of this transition from Earthlike to Venuslike is not known, but is estimated to have occurred around 4 billion years ago. The runaway greenhouse effect may have been caused by the evaporation of the surface water and the rise of the levels of greenhouse gases that followed. Venus's atmosphere has therefore received a great deal of attention from those studying climate change on Earth.[7]

There are no geologic forms on the planet to suggest the presence of water over the past billion years. However, there is no reason to suppose that Venus was an exception to the processes that formed Earth and gave it its water during its early history, possibly from the original rocks that formed the planet or later on from comets. The common view among research scientists is that water would have existed for about 600 million years on the surface before evaporating, though some such as David Grinspoon believe that up to 2 billion years could also be plausible.[63]

The early Earth during the Hadean eon is believed by most scientists to have had a Venus-like atmosphere, with roughly 100 bar of CO2 and a surface temperature of 230 °C, and possibly even sulfuric acid clouds, until about 4.0 billion years ago, by which time plate tectonics were in full force and together with the early water oceans, removed the CO2 and sulfur from the atmosphere.[64] Early Venus would thus most likely have had water oceans like the Earth, but any plate tectonics would have ended when Venus lost its oceans[citation needed]. Its surface is estimated to be about 500 million years old, so it would not be expected to show evidence of plate tectonics.[65]

Observations and measurement from Earth

Venus transits the face of the Sun on June 8, 2004, providing valuable information on the upper atmosphere through spectroscopic measurements from Earth

In 1761, Russian polymath Mikhail Lomonosov observed an arc of light surrounding the part of Venus off the Sun's disc at the beginning of the egress phase of the transit and concluded that Venus has an atmosphere.[66][67] In 1940, Rupert Wildt calculated that the amount of CO2 in the Venusian atmosphere would raise surface temperature above the boiling point for water.[68] This was confirmed when Mariner 2 made radiometer measurements of the temperature in 1962. In 1967, Venera 4 confirmed that the atmosphere consisted primarily of carbon dioxide.[68]

The upper atmosphere of Venus can be measured from Earth when the planet crosses the sun in a rare event known as a solar transit. The last solar transit of Venus occurred in 2012. Using quantitative astronomical spectroscopy, scientists were able to analyse sunlight that passed through the planet's atmosphere to reveal chemicals within it. As the technique to analyse light to discover information about a planet's atmosphere only first showed results in 2001,[69] this was the first opportunity to gain conclusive results in this way on the atmosphere of Venus since observation of solar transits began. This solar transit was a rare opportunity considering the lack of information on the atmosphere between 65 and 85 km.[70] The solar transit in 2004 enabled astronomers to gather a large amount of data useful not only in determining the composition of the upper atmosphere of Venus, but also in refining techniques used in searching for extrasolar planets. The atmosphere of mostly CO2, absorbs near-infrared radiation, making it easy to observe. During the 2004 transit, the absorption in the atmosphere as a function of wavelength revealed the properties of the gases at that altitude. The Doppler shift of the gases also enabled wind patterns to be measured.[71]

A solar transit of Venus is an extremely rare event, and the last solar transit of the planet before 2004 was in 1882. The most recent solar transit was in 2012; the next one will not occur until 2117.[70][71]

Space missions

Recent and current spaceprobes

The Venus Express spacecraft formerly in orbit around the planet probed deeper into the atmosphere using infrared imaging spectroscopy in the 1–5 µm spectral range.[3]

The JAXA probe Akatsuki, launched in May 2010, is studying the planet for a period of two years, including the structure and activity of the atmosphere, but it failed to enter Venus orbit in December 2010. A second attempt to achieve orbit succeeded 7 December 2015.[72] One of its five cameras known as the "IR2" will be able to probe the atmosphere of the planet underneath its thick clouds, in addition to its movement and distribution of trace components. With a highly eccentric orbit (periapsis altitude of 400 km and apoapsis of 310,000 km), it will be able to take close-up photographs of the planet, and should also confirm the presence of both active volcanoes as well as lightning.[73]

Venus In-Situ Explorer proposed by NASA's New Frontiers program

Proposed missions

The Venus In-Situ Explorer, proposed by NASA's New Frontiers program is a proposed probe which would aid in understanding the processes on the planet that led to climate change, as well as paving the way towards a later sample return mission.[74]

A craft called the Venus Mobile Explorer has been proposed by the Venus Exploration Analysis Group (VEXAG) to study the composition and isotopic measurements of the surface and the atmosphere, for about 90 days. The mission has not been selected for launch.[75]

After missions discovered the reality of the harsh nature of the planet's surface, attention shifted towards other targets such as Mars. There have been a number of proposed missions afterwards however, and many of these involve the little-known upper atmosphere. The Soviet Vega program in 1985 dropped two balloons into the atmosphere, but these were battery-powered and lasted for only about two Earth days each before running out of power. Since then, there has been no exploration of the upper atmosphere. In 2002, the NASA contractor Global Aerospace proposed a balloon that would be capable of staying in the upper atmosphere for hundreds of Earth days as opposed to two.[76]

A solar flyer has also been proposed by Geoffrey A. Landis in place of a balloon,[23] and the idea has been featured from time to time since the early 2000s. Venus has a high albedo, and reflects most of the sunlight that shines on it making the surface quite dark, the upper atmosphere at 60 km has an upward solar intensity of 90%, meaning that solar panels on both the top and the bottom of a craft could be used with nearly equal efficiency.[39] In addition to this, the slightly lower gravity, high air pressure and slow rotation allowing for perpetual solar power make this part of the planet ideal for exploration. The proposed flyer would operate best at an altitude where sunlight, air pressure, and wind speed would enable it to remain in the air perpetually, with slight dips down to lower altitudes for a few hours at a time before returning to higher altitudes. As sulfuric acid in the clouds at this height is not a threat for a properly shielded craft, this so-called "solar flyer" would be able to measure the area in between 45 km and 60 km indefinitely, for however long it takes for mechanical error or unforeseen problems to cause it to fail. Landis also proposed that rovers similar to Spirit and Opportunity could possibly explore the surface, with the difference being that Venus surface rovers would be "dumb" rovers controlled by radio signals from computers located in the flyer above,[77] only requiring parts such as motors and transistors to withstand the surface conditions, but not weaker parts involved in microelectronics that could not be made resistant to the heat, pressure and acidic conditions.[78]

Russian space plan for 2006–2015 involves a launch of Venera-D (Venus-D) probe around 2024.[79] The main scientific goals of the Venera-D mission are investigation of the structure and chemical composition of the atmosphere and investigation of the upper atmosphere, ionosphere, electrical activity, magnetosphere and escape rate.[80] It has been proposed to fly together with Venera-D an inflatable aircraft designed by Northrop Grumman, called Venus Atmospheric Maneuverable Platform (VAMP).[81][82][83]

The High Altitude Venus Operational Concept (HAVOC) is a NASA concept for a manned exploration of Venus. Rather than traditional landings, it would send crews into the upper atmosphere, using dirigibles. Other proposals from the late 2010s include VERITAS, Venus Origins Explorer, VISAGE, and VICI.

Mitochondrial disease

From Wikipedia, the free encyclopedia
 
Mitochondrial disease
Ragged red fibres - gtc - very high mag.jpg
Micrograph showing ragged red fibers, a finding seen in various types of mitochondrial diseases. Muscle biopsy. Gomori trichrome stain.
Specialty Medical genetics

Mitochondrial diseases are a group of disorders caused by dysfunctional mitochondria, the organelles that generate energy for the cell. Mitochondria are found in every cell of the human body except red blood cells, and convert the energy of food molecules into the ATP that powers most cell functions.

Mitochondrial diseases are sometimes (about 15% of the time)[1] caused by mutations in the mitochondrial DNA that affect mitochondrial function. Other mitochondrial diseases are caused by mutations in genes of the nuclear DNA, whose gene products are imported into the mitochondria (mitochondrial proteins) as well as acquired mitochondrial conditions. Mitochondrial diseases take on unique characteristics both because of the way the diseases are often inherited and because mitochondria are so critical to cell function. The subclass of these diseases that have neuromuscular disease symptoms are often called a mitochondrial myopathy.

Signs and symptoms

Symptoms include: poor growth, loss of muscle coordination, muscle weakness, visual problems, hearing problems, learning disabilities, heart disease, liver disease, kidney disease, gastrointestinal disorders, respiratory disorders, neurological problems, autonomic dysfunction and dementia.[2] Acquired conditions in which mitochondrial dysfunction has been involved are: diabetes, Huntington's disease, cancer, Alzheimer's disease, Parkinson's disease, bipolar disorder,[3][4][5] schizophrenia, aging and senescence, anxiety disorders, cardiovascular disease, sarcopenia and chronic fatigue syndrome.[6]

The body, and each mutation, is modulated by other genome variants; the mutation that in one individual may cause liver disease might in another person cause a brain disorder. The severity of the specific defect may also be great or small. Some defects include "exercise intolerance". Defects often affect the operation of the mitochondria and multiple tissues more severely, leading to multi-system diseases.[7]

As a rule, mitochondrial diseases are worse when the defective mitochondria are present in the muscles, cerebrum, or nerves,[8] because these cells use more energy than most other cells in the body.

Although mitochondrial diseases vary greatly in presentation from person to person, several major clinical categories of these conditions have been defined, based on the most common phenotypic features, symptoms, and signs associated with the particular mutations that tend to cause them.

An outstanding question and area of research is whether ATP depletion or reactive oxygen species are in fact responsible for the observed phenotypic consequences.

Cerebellar atrophy or hypoplasia has sometimes been reported to be associated.[9]

Causes

Mitochondrial disorders may be caused by mutations (acquired or inherited), in mitochondrial DNA (mtDNA), or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondrial dysfunction due to adverse effects of drugs, infections, or other environmental causes (see MeSH).

Nuclear DNA has two copies per cell (except for sperm and egg cells), one copy being inherited from the father and the other from the mother. Mitochondrial DNA, however, is strictly inherited from the mother and each mitochondrial organelle typically contains between 2 and 10 mtDNA copies. During cell division the mitochondria segregate randomly between the two new cells. Those mitochondria make more copies, normally reaching 500 mitochondria per cell. As mtDNA is copied when mitochondria proliferate, they can accumulate random mutations, a phenomenon called heteroplasmy. If only a few of the mtDNA copies inherited from the mother are defective, mitochondrial division may cause most of the defective copies to end up in just one of the new mitochondria (for more detailed inheritance patterns, see human mitochondrial genetics). Mitochondrial disease may become clinically apparent once the number of affected mitochondria reaches a certain level; this phenomenon is called "threshold expression".

Mitochondrial DNA mutations occur frequently, due to the lack of the error checking capability that nuclear DNA has (see Mutation rate). This means that mitochondrial DNA disorders may occur spontaneously and relatively often. Defects in enzymes that control mitochondrial DNA replication (all of which are encoded for by genes in the nuclear DNA) may also cause mitochondrial DNA mutations.

Most mitochondrial function and biogenesis is controlled by nuclear DNA. Human mitochondrial DNA encodes 13 proteins of the respiratory chain, while most of the estimated 1,500 proteins and components targeted to mitochondria are nuclear-encoded. Defects in nuclear-encoded mitochondrial genes are associated with hundreds of clinical disease phenotypes including anemia, dementia, hypertension, lymphoma, retinopathy, seizures, and neurodevelopmental disorders.[10]

A study by Yale University researchers (published in the February 12, 2004 issue of the New England Journal of Medicine) explored the role of mitochondria in insulin resistance among the offspring of patients with type 2 diabetes.[11] Other studies have shown that the mechanism may involve the interruption of the mitochondrial signaling process in body cells (intramyocellular lipids). A study conducted at the Pennington Biomedical Research Center in Baton Rouge, Louisiana[12] showed that this, in turn, partially disables the genes that produce mitochondria.

Examples

Examples of mitochondrial diseases include:
Conditions such as Friedreich's ataxia can affect the mitochondria but are not associated with mitochondrial proteins.

Mechanisms

The effective overall energy unit for the available body energy is referred to as the daily glycogen generation capacity,[13][14][15] and is used to compare the mitochondrial output of healthy individuals to that of afflicted or chronically glycogen-depleted individuals. This value is slow to change in a given individual, as it takes between 18 and 24 months to complete a full cycle.[14]

The glycogen generation capacity is entirely dependent on, and determined by, the operating levels of the mitochondria in all of the cells of the human body;[16] however, the relation between the energy generated by the mitochondria and the glycogen capacity is very loose and is mediated by many biochemical pathways.[13] The energy output of full healthy mitochondrial function can be predicted exactly by a complicated theoretical argument, but this argument is not straightforward, as most energy is consumed by the brain and is not easily measurable.

Diagnosis

Mitochondrial diseases are usually detected by analysing muscle samples, where the presence of these organelles is higher. The most common tests for the detection of these diseases are:
  1. Southern blot to detect big deletions or duplications
  2. PCR and specific mutation analysis
  3. Sequencing

Treatments

Although research is ongoing, treatment options are currently limited; vitamins are frequently prescribed, though the evidence for their effectiveness is limited.[17] Pyruvate has been proposed in 2007 as a treatment option.[18] N-acetyl cysteine reverses many models of mitochondrial dysfunction.[19]. In the case of mood disorders, specifically bipolar disorder, it is hypothesized that N-acetyl-cysteine (NAC), acetyl-L-carnitine (ALCAR), S-adenosylmethionine (SAMe), coenzyme Q10 (CoQ10), alpha-lipoic acid (ALA), creatine monohydrate (CM), and melatonin could be potential treatment options. [20]

Gene therapy prior to conception

Spindle transfer, where the nuclear DNA is transferred to another healthy egg cell leaving the defective mitochondrial DNA behind, is a potential treatment procedure that has been successfully carried out on monkeys.[21][22] Using a similar pronuclear transfer technique, researchers at Newcastle University led by Douglass Turnbull successfully transplanted healthy DNA in human eggs from women with mitochondrial disease into the eggs of women donors who were unaffected. In such cases, ethical questions have been raised regarding biological motherhood, since the child receives genes and gene regulatory molecules from two different women. Using genetic engineering in attempts to produce babies free of mitochondrial disease is controversial in some circles and raises important ethical issues.[25][26] A male baby was born in Mexico in 2016 from a mother with Leigh syndrome using spindle transfer.[27]

In September 2012 a public consultation was launched in the UK to explore the ethical issues involved.[28] Human genetic engineering was used on a small scale to allow infertile women with genetic defects in their mitochondria to have children.[29] In June 2013, the United Kingdom government agreed to develop legislation that would legalize the 'three-person IVF' procedure as a treatment to fix or eliminate mitochondrial diseases that are passed on from mother to child. The procedure could be offered from 29 October 2015 once regulations had been established.[30][31][32]  Embryonic mitochondrial transplant and protofection have been proposed as a possible treatment for inherited mitochondrial disease, and allotopic expression of mitochondrial proteins as a radical treatment for mtDNA mutation load.

Currently, human clinical trials are underway at GenSight Biologics (ClinicalTrials.gov # NCT02064569) and the University of Miami (ClinicalTrials.gov # NCT02161380) to examine the safety and efficacy of mitochondrial gene therapy in Leber's hereditary optic neuropathy.

Epidemiology

About 1 in 4,000 children in the United States will develop mitochondrial disease by the age of 10 years. Up to 4,000 children per year in the US are born with a type of mitochondrial disease.[33] Because mitochondrial disorders contain many variations and subsets, some particular mitochondrial disorders are very rare.

The average number of births per year among women at risk for transmitting mtDNA disease is estimated to approximately 150 in the United Kingdom and 800 in the United States.[34]

History

The first pathogenic mutation in mitochondrial DNA was identified in 1988; from that time to 2016, around 275 other disease-causing mutations were identified.[35]:37

Notable cases

Notable people who suffered from mitochondrial disease include:
  • Mattie Stepanek, a poet, peace advocate, and motivational speaker who suffered from dysautonomic mitochondrial myopathy, and who died at age 13.
  • Rocco Baldelli, a coach and former center fielder in Major League Baseball who had to retire from active play at age 29 due to mitochondrial channelopathy.
  • Charlie Gard, a British boy who suffered from mitochondrial DNA depletion syndrome; decisions about his care were taken to various law courts.
  • Greg Lemond, American champion cyclist that developed mitochondrial myopathy after being shot in a hunting accident. Aluminum leached into his bloodstream from the remaining shotgun pellets that surgeons were unable to remove.

Entropy (information theory)

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