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Tuesday, May 16, 2023

William James

From Wikipedia, the free encyclopedia
William James
A black and white photograph of James
    James in 1903
BornJanuary 11, 1842
New York City, U.S.
DiedAugust 26, 1910 (aged 68)
Alma materHarvard University (MD)
RelativesHenry James Sr. (father)
Henry James (brother)
Alice James (sister)

Era19th-/20th-century philosophy
RegionWestern philosophy
School
InstitutionsHarvard University
Notable students

William James (January 11, 1842 – August 26, 1910) was an American philosopher, historian, and psychologist, and the first educator to offer a psychology course in the United States. James is considered to be a leading thinker of the late 19th century, one of the most influential philosophers of the United States, and the "Father of American psychology".

Along with Charles Sanders Peirce, James established the philosophical school known as pragmatism, and is also cited as one of the founders of functional psychology. A Review of General Psychology analysis, published in 2002, ranked James as the 14th most eminent psychologist of the 20th century. A survey published in American Psychologist in 1991 ranked James's reputation in second place, after Wilhelm Wundt, who is widely regarded as the founder of experimental psychology. James also developed the philosophical perspective known as radical empiricism. James's work has influenced philosophers and academics such as Émile Durkheim, W. E. B. Du Bois, Edmund Husserl, Bertrand Russell, Ludwig Wittgenstein, Hilary Putnam, Richard Rorty, and Marilynne Robinson.

Born into a wealthy family, James was the son of the Swedenborgian theologian Henry James Sr. and the brother of both the prominent novelist Henry James and the diarist Alice James. James trained as a physician and taught anatomy at Harvard, but never practiced medicine. Instead, he pursued his interests in psychology and then philosophy. He wrote widely on many topics, including epistemology, education, metaphysics, psychology, religion, and mysticism. Among his most influential books are The Principles of Psychology, a groundbreaking text in the field of psychology; Essays in Radical Empiricism, an important text in philosophy; and The Varieties of Religious Experience, an investigation of different forms of religious experience, including theories on mind-cure.

Early life

William James in Brazil, 1865

William James was born at the Astor House in New York City on January 11, 1842. He was the son of Henry James Sr., a noted and independently wealthy Swedenborgian theologian well acquainted with the literary and intellectual elites of his day. The intellectual brilliance of the James family milieu and the remarkable epistolary talents of several of its members have made them a subject of continuing interest to historians, biographers, and critics.

William James received an eclectic trans-Atlantic education, developing fluency in both German and French. Education in the James household encouraged cosmopolitanism. The family made two trips to Europe while William James was still a child, setting a pattern that resulted in thirteen more European journeys during his life. James wished to pursue painting, his early artistic bent led to an apprenticeship in the studio of William Morris Hunt in Newport, Rhode Island, but his father urged him to become a physician instead. Since this did not align with James's interests, he stated that he wanted to specialize in physiology. Once he figured this was also not what he wanted to do, he then announced he was going to specialize in the nervous system and psychology. James then switched in 1861 to scientific studies at the Lawrence Scientific School of Harvard College.

In his early adulthood, James suffered from a variety of physical ailments, including those of the eyes, back, stomach, and skin. He was also tone deaf. He was subject to a variety of psychological symptoms which were diagnosed at the time as neurasthenia, and which included periods of depression during which he contemplated suicide for months on end. Two younger brothers, Garth Wilkinson (Wilkie) and Robertson (Bob), fought in the Civil War. James himself was an advocate of peace. He suggested that instead of youth serving in the military that they serve the public in a term of service, "to get the childishness knocked out of them." The other three siblings (William, Henry, and Alice James) all suffered from periods of invalidism.

He took up medical studies at Harvard Medical School in 1864 (according to his brother Henry James, the author). He took a break in the spring of 1865 to join naturalist Louis Agassiz on a scientific expedition up the Amazon River, but aborted his trip after eight months, as he suffered bouts of severe seasickness and mild smallpox. His studies were interrupted once again due to illness in April 1867. He traveled to Germany in search of a cure and remained there until November 1868; at that time he was 26 years old. During this period, he began to publish; reviews of his works appeared in literary periodicals such as the North American Review.

James finally earned his MD degree in June 1869 but he never practiced medicine. What he called his "soul-sickness" would only be resolved in 1872, after an extended period of philosophical searching. He married Alice Gibbens in 1878. In 1882 he joined the Theosophical Society.

James's time in Germany proved intellectually fertile, helping him find that his true interests lay not in medicine but in philosophy and psychology. Later, in 1902 he would write: "I originally studied medicine in order to be a physiologist, but I drifted into psychology and philosophy from a sort of fatality. I never had any philosophic instruction, the first lecture on psychology I ever heard being the first I ever gave".

Career

James interacted with a wide array of writers and scholars throughout his life, including his godfather Ralph Waldo Emerson, his godson William James Sidis, as well as Charles Sanders Peirce, Bertrand Russell, Josiah Royce, Ernst Mach, John Dewey, Macedonio Fernández, Walter Lippmann, Mark Twain, Horatio Alger, G. Stanley Hall, Henri Bergson, Carl Jung, Jane Addams and Sigmund Freud.

James spent almost all of his academic career at Harvard. He was appointed instructor in physiology for the spring 1873 term, instructor in anatomy and physiology in 1873, assistant professor of psychology in 1876, assistant professor of philosophy in 1881, full professor in 1885, endowed chair in psychology in 1889, return to philosophy in 1897, and emeritus professor of philosophy in 1907.

James studied medicine, physiology, and biology, and began to teach in those subjects, but was drawn to the scientific study of the human mind at a time when psychology was constituting itself as a science. James's acquaintance with the work of figures like Hermann Helmholtz in Germany and Pierre Janet in France facilitated his introduction of courses in scientific psychology at Harvard University. He taught his first experimental psychology course at Harvard in the 1875–1876 academic year.

During his Harvard years, James joined in philosophical discussions and debates with Charles Peirce, Oliver Wendell Holmes, and Chauncey Wright that evolved into a lively group informally known as The Metaphysical Club in 1872. Louis Menand (2001) suggested that this Club provided a foundation for American intellectual thought for decades to come. James joined the Anti-Imperialist League in 1898, in opposition to the United States annexation of the Philippines.

William James and Josiah Royce, near James's country home in Chocorua, New Hampshire in September 1903. James's daughter Peggy took the picture. On hearing the camera click, James cried out: "Royce, you're being photographed! Look out! I say Damn the Absolute!"

Among James's students at Harvard University were Boris Sidis, Theodore Roosevelt, George Santayana, W. E. B. Du Bois, G. Stanley Hall, Ralph Barton Perry, Gertrude Stein, Horace Kallen, Morris Raphael Cohen, Walter Lippmann, Alain Locke, C. I. Lewis, and Mary Whiton Calkins. Antiquarian bookseller Gabriel Wells tutored under him at Harvard in the late 1890s.

His students enjoyed his brilliance and his manner of teaching was free of personal arrogance. They remember him for his kindness and humble attitude. His respectful attitude towards them speaks well of his character.

Following his January 1907 retirement from Harvard, James continued to write and lecture, publishing Pragmatism, A Pluralistic Universe, and The Meaning of Truth. James was increasingly afflicted with cardiac pain during his last years. It worsened in 1909 while he worked on a philosophy text (unfinished but posthumously published as Some Problems in Philosophy). He sailed to Europe in the spring of 1910 to take experimental treatments which proved unsuccessful, and returned home on August 18. His heart failed on August 26, 1910, at his home in Chocorua, New Hampshire. He was buried in the family plot in Cambridge Cemetery, Cambridge, Massachusetts.

He was one of the strongest proponents of the school of functionalism in psychology and of pragmatism in philosophy. He was a founder of the American Society for Psychical Research, as well as a champion of alternative approaches to healing. In 1884 and 1885 he became president of the British Society for Psychical Research for which he wrote in Mind and in the Psychological Review. He challenged his professional colleagues not to let a narrow mindset prevent an honest appraisal of those beliefs.

In an empirical study by Haggbloom et al. using six criteria such as citations and recognition, James was found to be the 14th most eminent psychologist of the 20th century.

Family

William James was the son of Henry James (Senior) of Albany, and Mary Robertson Walsh. He had four siblings: Henry (the novelist), Garth Wilkinson, Robertson, and Alice. William became engaged to Alice Howe Gibbens on May 10, 1878; they were married on July 10. They had 5 children: Henry (born May 18, 1879), William (June 17, 1882 – 1961), Herman (born 1884, died in infancy), Margaret (born March 1887) and Alexander (the artist) (born December 22, 1890). Most of William James's ancestors arrived in America from Scotland or Ireland in the 18th century. Many of them settled in eastern New York or New Jersey. All of James's ancestors were Protestant, well educated, and of character. Within their communities, they worked as farmers, merchants, and traders who were all heavily involved with their church. The last ancestor to arrive in America was William James's paternal grandfather also named William James. He came to America from Ballyjamesduff, County Cavan, Ireland in 1789 when he was 18 years old. There is suspicion that he fled to America because his family tried to force him into the ministry. After traveling to America with no money left, he found a job at a store as a clerk. After continuously working, he was able to own the store himself. As he traveled west to find more job opportunities, he was involved in various jobs such as the salt industry and the Erie Canal project. After being a significant worker in the Erie Canal project and helping Albany become a major center of trade, he then became the first Vice-President of the Albany Savings Bank. William James (grandfather) went from being a poor Irish immigrant to one of the richest men in New York. After his death, his son Henry James inherited his fortune and lived in Europe and the United States searching for the meaning of life.

Writings

William James wrote voluminously throughout his life. A non-exhaustive bibliography of his writings, compiled by John McDermott, is 47 pages long.

He gained widespread recognition with his monumental The Principles of Psychology (1890), totaling twelve hundred pages in two volumes, which took twelve years to complete. Psychology: The Briefer Course, was an 1892 abridgement designed as a less rigorous introduction to the field. These works criticized both the English associationist school and the Hegelianism of his day as competing dogmatisms of little explanatory value, and sought to re-conceive the human mind as inherently purposive and selective.

President Jimmy Carter's Moral Equivalent of War Speech, on April 17, 1977, equating the United States' 1970s energy crisis, oil crisis and the changes and sacrifices Carter's proposed plans would require with the "moral equivalent of war," may have borrowed its title, much of its theme and the memorable phrase from James's classic essay "The Moral Equivalent of War" derived from his last speech, delivered at Stanford University in 1906, and published in 1910, in which "James considered one of the classic problems of politics: how to sustain political unity and civic virtue in the absence of war or a credible threat ..." and which "... sounds a rallying cry for service in the interests of the individual and the nation."

In simple terms, his philosophy and writings can be understood as an emphasis on "fruits over roots," a reflection of his pragmatist tendency to focus on the practical consequences of ideas rather than become mired in unproductive metaphysical arguments or fruitless attempts to ground truth in abstract ways. Ever the empiricist, James believes we are better off evaluating the fruitfulness of ideas by testing them in the common ground of lived experience.

James was remembered as one of America's representative thinkers, psychologist, and philosopher. William James was also one of the most influential writers on religion, psychical research, and self-help. He was told to have a few disciples that followed his writing since they were inspired and enriched by his research.

Epistemology

Portrait of William James by John La Farge, c. 1859

James defined true beliefs as those that prove useful to the believer. His pragmatic theory of truth was a synthesis of correspondence theory of truth and coherence theory of truth, with an added dimension. Truth is verifiable to the extent that thoughts and statements correspond with actual things, as well as the extent to which they "hang together," or cohere, as pieces of a puzzle might fit together; these are in turn verified by the observed results of the application of an idea to actual practice.

The most ancient parts of truth … also once were plastic. They also were called true for human reasons. They also mediated between still earlier truths and what in those days were novel observations. Purely objective truth, truth in whose establishment the function of giving human satisfaction in marrying previous parts of experience with newer parts played no role whatsoever, is nowhere to be found. The reasons why we call things true is the reason why they are true, for 'to be true' means only to perform this marriage-function.

— "Pragmatism's Conception of Truth," Pragmatism (1907), p. 83.

James held a world view in line with pragmatism, declaring that the value of any truth was utterly dependent upon its use to the person who held it. Additional tenets of James's pragmatism include the view that the world is a mosaic of diverse experiences that can only be properly interpreted and understood through an application of 'radical empiricism.' Radical empiricism, not related to the everyday scientific empiricism, asserts that the world and experience can never be halted for an entirely objective analysis; the mind of the observer and the act of observation affect any empirical approach to truth. The mind, its experiences, and nature are inseparable. James's emphasis on diversity as the default human condition—over and against duality, especially Hegelian dialectical duality—has maintained a strong influence in American culture. James's description of the mind-world connection, which he described in terms of a 'stream of consciousness,' had a direct and significant impact on avant-garde and modernist literature and art, notably in the case of James Joyce.

In "What Pragmatism Means" (1906), James writes that the central point of his own doctrine of truth is, in brief:

Truths emerge from facts, but they dip forward into facts again and add to them; which facts again create or reveal new truth (the word is indifferent) and so on indefinitely. The 'facts' themselves meanwhile are not true. They simply are. Truth is the function of the beliefs that start and terminate among them.

Richard Rorty made the contested claim that James did not mean to give a theory of truth with this statement and that we should not regard it as such. However, other pragmatism scholars such as Susan Haack and Howard Mounce do not share Rorty's instrumentalist interpretation of James.

In The Meaning of Truth (1909), James seems to speak of truth in relativistic terms, in reference to critics of pragmatism: "The critic's trouble … seems to come from his taking the word 'true' irrelatively, whereas the pragmatist always means 'true for him who experiences the workings.'" However, James responded to critics accusing him of relativism, scepticism, or agnosticism, and of believing only in relative truths. To the contrary, he supported an epistemological realism position.

Pragmatism and "cash value"

Pragmatism is a philosophical approach that seeks to both define truth and resolve metaphysical issues. William James demonstrates an application of his method in the form of a simple story:

A live squirrel supposed to be clinging on one side of a tree-trunk; while over against the tree's opposite side a human being was imagined to stand. This human witness tries to get sight of the squirrel by moving rapidly round the tree, but no matter how fast he goes, the squirrel moves as fast in the opposite direction, and always keeps the tree between himself and the man, so that never a glimpse of him is caught. The resultant metaphysical problem now is this: Does the man go round the squirrel or not?

James solves the issue by making a distinction between practical meaning. That is, the distinction between meanings of "round." Round in the sense that the man occupies the space north, east, south, and west of the squirrel; and round in the sense that the man occupies the space facing the squirrel's belly, back and sides. Depending on what the debaters meant by "going round," the answer would be clear. From this example James derives the definition of the pragmatic method: to settle metaphysical disputes, one must simply make a distinction of practical consequences between notions, then, the answer is either clear, or the "dispute is idle."

Both James and his colleague, Charles Sanders Peirce, coined the term "cash value":

When he said that the whole meaning of a (clear) conception consists in the entire set of its practical consequences, he had in mind that a meaningful conception must have some sort of experiential "cash value," must somehow be capable of being related to some sort of collection of possible empirical observations under specifiable conditions.

A statement's truthfulness is verifiable through its correspondence to reality, and its observable effects of putting the idea to practice. For example, James extends his Pragmatism to the hypothesis of God: "On pragmatic principles, if the hypothesis of God works satisfactorily in the widest sense of the word, it is true. … The problem is to build it out and determine it so that it will combine satisfactorily with all the other working truths."

From this, we also know that "new" truths must also correspond to already existent truths as well.

From the introduction by Bruce Kuklick (1981, p. xiv) to James's Pragmatism:

James went on to apply the pragmatic method to the epistemological problem of truth. He would seek the meaning of "true" by examining how the idea functioned in our lives. A belief was true, he said, if it worked for all of us, and guided us expeditiously through our semihospitable world. James was anxious to uncover what true beliefs amounted to in human life, what their "cash value" was, and what consequences they led to. A belief was not a mental entity which somehow mysteriously corresponded to an external reality if the belief were true. Beliefs were ways of acting with reference to a precarious environment, and to say they were true was to say they were efficacious in this environment. In this sense the pragmatic theory of truth applied Darwinian ideas in philosophy; it made survival the test of intellectual as well as biological fitness.

James's book of lectures on pragmatism is arguably the most influential book of American philosophy. The lectures inside depict his position on the subject. In his sixth lecture, he begins by defining truth as "agreement with reality." With this, James warns that there will be disagreements between pragmatics and intellectualists over the concepts of "agreement" and "reality", the last reasoning before thoughts settle and become autonomous for us. However, he contrasts this by supporting a more practical interpretation that: a true idea or belief is one that we can blend with our thinking so that it can be justified through experiences.

If theological ideas prove to have a value for concrete life, they will be true, for pragmatism, in the sense of being good for so much. For how much more they are true, will depend entirely on their relations to the other truths that also have to be acknowledged.

— Pragmatism (1907), p. 29

Whereby the agreement of truths with "reality" results in useful outcomes, "the 'reality' with which truths must agree has three dimensions:"

  1. "matters of fact;"
  2. "relations of ideas;" and
  3. "the entire set of other truths to which we are committed."

According to James's pragmatic approach to belief, knowledge is commonly viewed as a justified and true belief. James will accept a view if its conception of truth is analyzed and justified through interpretation, pragmatically. As a matter of fact, James's whole philosophy is of productive beliefs.

Belief in anything involves conceiving of how it is real, but disbelief is the result when we dismiss something because it contradicts another thing we think of as real. In his "Sentiment of Rationality", saying that crucial beliefs are not known is to doubt their truth, even if it seems possible. James names four "postulates of rationality" as valuable but unknowable: God, immorality, freedom, and moral duty.

In contrast, the weak side to pragmatism is that the best justification for a claim is whether it works. However, a claim that does not have outcomes cannot be justified, or unjustified, because it will not make a difference.

"There can be no difference that doesn't make a difference."

— Pragmatism (1907), p. 45

When James moves on to then state that pragmatism's goal is ultimately "to try to interpret each notion by tracing its respective practical consequences," he does not clarify what he means by "practical consequences." On the other hand, his friend, colleague, and another key founder in establishing pragmatist beliefs, Charles S. Peirce, dives deeper in defining these consequences. For Peirce, "the consequences we are concerned with are general and intelligible." He further explains this in his 1878 paper "How to Make Ideas Clear," when he introduces a maxim that allows one to interpret consequences as grades of clarity and conception. Describing how everything is derived from perception, Peirce uses the example of the doctrine of transubstantiation to show exactly how he defines practical consequences. Protestants interpret the bread and wine of the Eucharist is flesh and blood in only a subjective sense, while Catholics would label them as actual, and divinely mystical properties of flesh via the "body, blood, soul, and divinity", even with the physical properties remaining as bread and wine in appearance. But to everyone, there can be no knowledge of the wine and bread of the Eucharist unless it is established that either wine and bread possesses certain properties or that anything that is interpreted as the blood and body of Christ is the blood and body of Christ. With this Peirce declares that "our action has exclusive reference to what affects the senses," and that we can mean nothing by transubstantiation than "what has certain effects, direct or indirect, upon our senses." In this sense, James's pragmatic influencer Peirce establishes that what counts as a practical consequence or effect is what can affect one's senses and what is comprehendible and fathomable in the natural world.

Yet James never "[works] out his understanding of 'practical consequences' as fully as Peirce did," nor does he limit these consequences to the senses like Peirce. It then raises the question: what does it mean to be practical? Whether James means the greatest number of positive consequences (in light of utilitarianism), a consequence that considers other perspectives (like his compromise of the tender and tough ways of thinking), or a completely different take altogether, it is unclear to truly tell what consequence truly fits the pragmatic standard, and what doesn't. The closest James is able to get in explaining this idea is by telling his audience to weigh the difference it would "practically make to anyone" if one opinion over the other were true, and although he attempts to clarify it, he never specifies nor establishes the method in which one would weigh the difference between one opinion over the other. Thus, the flaw in his argument appears in that it is difficult to fathom how he would determine these practical consequences, which he continually refers to throughout his work, to be measured or interpreted.

Will to believe doctrine

In William James's 1896 lecture titled "The Will to Believe", James defends the right to violate the principle of evidentialism in order to justify hypothesis venturing. This idea foresaw 20th century objections to evidentialism and sought to ground justified belief in an unwavering principle that would prove more beneficial. Through his philosophy of pragmatism William James justifies religious beliefs by using the results of his hypothetical venturing as evidence to support the hypothesis's truth. Therefore, this doctrine allows one to assume belief in a god and prove its existence by what the belief brings to one's life.

This was criticized by advocates of skepticism rationality, like Bertrand Russell in Free Thought and Official Propaganda and Alfred Henry Lloyd with The Will to Doubt. Both argued that one must always adhere to fallibilism, recognizing of all human knowledge that "None of our beliefs are quite true; all have at least a penumbra of vagueness and error," and that the only means of progressing ever-closer to the truth is to never assume certainty, but always examine all sides and try to reach a conclusion objectively.

Free will

In his search for truth and assorted principles of psychology, William James developed his two-stage model of free will. In his model, he tries to explain how it is people come to the making of a decision and what factors are involved in it. He firstly defines our basic ability to choose as free will. Then he specifies our two factors as chance and choice. "James's two-stage model effectively separates chance (the in-deterministic free element) from choice (an arguably determinate decision that follows causally from one's character, values, and especially feelings and desires at the moment of decision)."

James argues that the question of free will revolves around "chance." The idea of chance is that some events are possibilities, things that could happen but are not guaranteed. Chance is a neutral term (it is, in this case, neither inherently positive nor "intrinsically irrational and preposterous," connotations it usually has); the only information it gives about the events to which it applies is that they are disconnected from other things – they are "not controlled, secured, or necessitated by other things" before they happen. Chance is made possible regarding our actions because our amount of effort is subject to change. If the amount of effort we put into something is predetermined, our actions are predetermined.

Free will in relation to effort also balances "ideals and propensities—the things you see as best versus the things that are easiest to do". Without effort, "the propensity is stronger than the ideal." To act according to your ideals, you must resist the things that are easiest, and this can only be done with effort. James states that the free will question is therefore simple: "it relates solely to the amount of effort of attention or consent which we can at any time put forth."

Chance is the 'free element,' that part of the model we have no control over. James says that in the sequence of the model, chance comes before choice. In the moment of decision we are given the chance to make a decision and then the choice is what we do (or do not do) regarding the decision.

When it comes to choice, James says we make a choice based on different experiences. It comes from our own past experiences, the observations of others, or:

A supply of ideas of the various movements that are … left in the memory by experiences of their involuntary performance is thus the first prerequisite of the voluntary life.

What James describes is that once you've made a decision in the past, the experience is stockpiled into your memory where it can be referenced the next time a decision must be made and will be drawn from as a positive solution. However, in his development of the design, James also struggled with being able to prove that free will is actually free or predetermined.

People can make judgements of regret, moral approval and moral disapproval, and if those are absent, then that means our will is predetermined. An example of this is "James says the problem is a very 'personal' one and that he cannot personally conceive of the universe as a place where murder must happen." Essentially, if there were no regrets or judgments then all the bad stuff would not be considered bad, only as predetermined because there are no options of 'good' and 'bad'. "The free will option is pragmatically truer because it better accommodates the judgments of regret and morality." Overall, James uses this line of reasoning to prove that our will is indeed free: because of our morality codes, and the conceivable alternate universes where a decision has been regarded different than what we chose.

In "The Will to Believe", James simply asserted that his will was free. As his first act of freedom, he said, he chose to believe his will was free. He was encouraged to do this by reading Charles Renouvier, whose work convinced James to convert from monism to pluralism. In his diary entry of April 30, 1870, James wrote:

I think that yesterday was a crisis in my life. I finished the first part of Renouvier's second Essais and see no reason why his definition of free will—"the sustaining of a thought because I choose to when I might have other thoughts"—need be the definition of an illusion. At any rate, I will assume for the present—until next year—that it is no illusion. My first act of free will shall be to believe in free will.

In 1884, James set the terms for all future discussions of determinism and compatibilism in the free will debates with his lecture to Harvard Divinity School students published as "The Dilemma of Determinism". In this talk he defined the common terms hard determinism and soft determinism (now more commonly called compatibilism).

Old-fashioned determinism was what we may call hard determinism. It did not shrink from such words as fatality, bondage of the will, necessitation, and the like. Nowadays, we have a soft determinism which abhors harsh words, and, repudiating fatality, necessity, and even predetermination, says that its real name is freedom; for freedom is only necessity understood, and bondage to the highest is identical with true freedom.

James called compatibilism a "quagmire of evasion," just as the ideas of Thomas Hobbes and David Hume—that free will was simply freedom from external coercion—were called a "wretched subterfuge" by Immanuel Kant.

Indeterminism is "the belief in freedom [which] holds that there is some degree of possibility that is not necessitated by the rest of reality." The word "some" in this definition is crucial in James's argument because it leaves room for a higher power, as it does not require that all events be random. Specifically, indeterminism does not say that no events are guaranteed or connected to previous events; instead, it says that some events are not guaranteed – some events are up to chance. In James's model of free will, choice is deterministic, determined by the person making it, and it "follows casually from one's character, values, and especially feelings and desires at the moment of decision." Chance, on the other hand, is indeterministic, and pertains to possibilities that could happen but are not guaranteed. James described chance as neither hard nor soft determinism, but "indeterminism":

The stronghold of the determinist argument is the antipathy to the idea of chance ... This notion of alternative possibility, this admission that any one of several things may come to pass is, after all, only a roundabout name for chance.

James asked the students to consider his choice for walking home from Lowell Lecture Hall after his talk:

What is meant by saying that my choice of which way to walk home after the lecture is ambiguous and matter of chance? ... It means that both Divinity Avenue and Oxford Street are called but only one, and that one either one, shall be chosen.

With this simple example, James laid out a two-stage decision process with chance in a present time of random alternatives, leading to a choice of one possibility that transforms an ambiguous future into a simple unalterable past. James's two-stage model separates chance (undetermined alternative possibilities) from choice (the free action of the individual, on which randomness has no effect). Subsequent thinkers using this model include Henri Poincaré, Arthur Holly Compton, and Karl Popper.

Philosophy of religion

Excerpt

James did important work in philosophy of religion. In his Gifford Lectures at the University of Edinburgh he provided a wide-ranging account of The Varieties of Religious Experience (1902) and interpreted them according to his pragmatic leanings. Some of the important claims he makes in this regard:

  • Religious genius (experience) should be the primary topic in the study of religion, rather than religious institutions—since institutions are merely the social descendant of genius.
  • The intense, even pathological varieties of experience (religious or otherwise) should be sought by psychologists, because they represent the closest thing to a microscope of the mind—that is, they show us in drastically enlarged form the normal processes of things.
  • In order to usefully interpret the realm of common, shared experience and history, we must each make certain "over-beliefs" in things which, while they cannot be proven on the basis of experience, help us to live fuller and better lives.
  • A variety of characteristics can be seen within a single individual. There are subconscious elements that compose the scattered fragments of a personality. This is the reflection of a greater dissociation which is the separation between science and religion.
  • Religious Mysticism is only one half of mysticism, the other half is composed of the insane and both of these are co-located in the 'great subliminal or transmarginal region'.

James investigated mystical experiences throughout his life, leading him to experiment with chloral hydrate (1870), amyl nitrite (1875), nitrous oxide (1882), and peyote (1896). James claimed that it was only when he was under the influence of nitrous oxide that he was able to understand Hegel. He concluded that while the revelations of the mystic hold true, they hold true only for the mystic; for others, they are certainly ideas to be considered, but can hold no claim to truth without personal experience of such. American Philosophy: An Encyclopedia classes him as one of several figures who "took a more pantheist or pandeist approach by rejecting views of God as separate from the world."

Mysticism

William James provided a description of the mystical experience, in his famous collection of lectures published in 1902 as The Varieties of Religious Experience. These criteria are as follows

  • Passivity – a feeling of being grasped and held by a superior power not under your own control.
  • Ineffability – no adequate way to use human language to describe the experience.
  • Noetic – universal truths revealed that are unable to be acquired anywhere else.
  • Transient – the mystical experience is only a temporary experience.

James's preference was to focus on human experience, leading to his research of the subconscious. This was the entryway for the awakening transformation of mystical states. Mystical states represent the peak of religious experience. This helped open James's inner process to self-discovery.

Instincts

Like Sigmund Freud, James was influenced by Charles Darwin's theory of natural selection. At the core of James's theory of psychology, as defined in The Principles of Psychology (1890), was a system of "instincts". James wrote that humans had many instincts, even more than other animals. These instincts, he said, could be overridden by experience and by each other, as many of the instincts were actually in conflict with each other. In the 1920s, however, psychology turned away from evolutionary theory and embraced radical behaviorism.

Theory of emotion

James is one of the two namesakes of the James–Lange theory of emotion, which he formulated independently of Carl Lange in the 1880s. The theory holds that emotion is the mind's perception of physiological conditions that result from some stimulus. In James's oft-cited example, it is not that we see a bear, fear it, and run; we see a bear and run; consequently, we fear the bear. Our mind's perception of the higher adrenaline level, heartbeat, etc. is the emotion.

This way of thinking about emotion has great consequences for the philosophy of aesthetics as well as to the philosophy and practice of education. Here is a passage from his work, The Principles of Psychology, that spells out those consequences:

[W]e must immediately insist that aesthetic emotion, pure and simple, the pleasure given us by certain lines and masses, and combinations of colors and sounds, is an absolutely sensational experience, an optical or auricular feeling that is primary, and not due to the repercussion backwards of other sensations elsewhere consecutively aroused. To this simple primary and immediate pleasure in certain pure sensations and harmonious combinations of them, there may, it is true, be added secondary pleasures; and in the practical enjoyment of works of art by the masses of mankind these secondary pleasures play a great part. The more classic one's taste is, however, the less relatively important are the secondary pleasures felt to be, in comparison with those of the primary sensation as it comes in. Classicism and romanticism have their battles over this point.

The theory of emotion was also independently developed in Italy by the anthropologist Giuseppe Sergi.

William James's bear

From Joseph LeDoux's description of William James's Emotion:

Why do we run away if we notice that we are in danger? Because we are afraid of what will happen if we don't. This obvious answer to a seemingly trivial question has been the central concern of a century-old debate about the nature of our emotions.

It all began in 1884 when William James published an article titled "What Is an Emotion?"

The article appeared in a philosophy journal called Mind, as there were no psychology journals yet. It was important, not because it definitively answered the question it raised, but because of the way in which James phrased his response. He conceived of an emotion in terms of a sequence of events that starts with the occurrence of an arousing stimulus (the sympathetic nervous system or the parasympathetic nervous system); and ends with a passionate feeling, a conscious emotional experience. A major goal of emotion research is still to elucidate this stimulus-to-feeling sequence—to figure out what processes come between the stimulus and the feeling.

James set out to answer his question by asking another: do we run from a bear because we are afraid or are we afraid because we run? He proposed that the obvious answer, that we run because we are afraid, was wrong, and instead argued that we are afraid because we run:

Our natural way of thinking about … emotions is that the mental perception of some fact excites the mental affection called emotion, and that this latter state of mind gives rise to the bodily expression. My theory, on the contrary, is that the bodily changes follow directly the perception of the exciting fact, and that our feeling of the same changes as they occur IS the emotion (called 'feeling' by Damasio).

The essence of James's proposal was simple. It was premised on the fact that emotions are often accompanied by bodily responses (racing heart, tight stomach, sweaty palms, tense muscles, and so on; sympathetic nervous system) and that we can sense what is going on inside our body much the same as we can sense what is going on in the outside world. According to James, emotions feel different from other states of mind because they have these bodily responses that give rise to internal sensations, and different emotions feel different from one another because they are accompanied by different bodily responses and sensations. For example, when we see James's bear, we run away. During this act of escape, the body goes through a physiological upheaval: blood pressure rises, heart rate increases, pupils dilate, palms sweat, muscles contract in certain ways (evolutionary, innate defense mechanisms). Other kinds of emotional situations will result in different bodily upheavals. In each case, the physiological responses return to the brain in the form of bodily sensations, and the unique pattern of sensory feedback gives each emotion its unique quality. Fear feels different from anger or love because it has a different physiological signature (the parasympathetic nervous system for love). The mental aspect of emotion, the feeling, is a slave to its physiology, not vice versa: we do not tremble because we are afraid or cry because we feel sad; we are afraid because we tremble and are sad because we cry.

Philosophy of history

One of the long-standing schisms in the philosophy of history concerns the role of individuals in social change.

One faction sees individuals (as seen in Dickens' A Tale of Two Cities and Thomas Carlyle's The French Revolution, A History) as the motive power of history, and the broader society as the page on which they write their acts. The other sees society as moving according to holistic principles or laws, and sees individuals as its more-or-less willing pawns. In 1880, James waded into this controversy with "Great Men, Great Thoughts, and the Environment", an essay published in the Atlantic Monthly. He took Carlyle's side, but without Carlyle's one-sided emphasis on the political/military sphere, upon heroes as the founders or overthrowers of states and empires.

A philosopher, according to James, must accept geniuses as a given entity the same way as a biologist accepts as an entity Darwin's "spontaneous variations". The role of an individual will depend on the degree of its conformity with the social environment, epoch, moment, etc.

James introduces a notion of receptivities of the moment. The societal mutations from generation to generation are determined (directly or indirectly) mainly by the acts or examples of individuals whose genius was so adapted to the receptivities of the moment or whose accidental position of authority was so critical that they became ferments, initiators of movements, setters of precedent or fashion, centers of corruption, or destroyers of other persons, whose gifts, had they had free play, would have led society in another direction.

View on spiritualism and associationism

James in a séance with a spiritualist medium

James studied closely the schools of thought known as associationism and spiritualism. The view of an associationist is that each experience that one has leads to another, creating a chain of events. The association does not tie together two ideas, but rather physical objects. This association occurs on an atomic level. Small physical changes occur in the brain which eventually form complex ideas or associations. Thoughts are formed as these complex ideas work together and lead to new experiences. Isaac Newton and David Hartley both were precursors to this school of thought, proposing such ideas as "physical vibrations in the brain, spinal cord, and nerves are the basis of all sensations, all ideas, and all motions …" James disagreed with associationism in that he believed it to be too simple. He referred to associationism as "psychology without a soul" because there is nothing from within creating ideas; they just arise by associating objects with one another.

On the other hand, a spiritualist believes that mental events are attributed to the soul. Whereas in associationism, ideas and behaviors are separate, in spiritualism, they are connected. Spiritualism encompasses the term innatism, which suggests that ideas cause behavior. Ideas of past behavior influence the way a person will act in the future; these ideas are all tied together by the soul. Therefore, an inner soul causes one to have a thought, which leads them to perform a behavior, and memory of past behaviors determine how one will act in the future.

James had a strong opinion about these schools of thought. He was, by nature, a pragmatist and thus took the view that one should use whatever parts of theories make the most sense and can be proven. Therefore, he recommended breaking apart spiritualism and associationism and using the parts of them that make the most sense. James believed that each person has a soul, which exists in a spiritual universe, and leads a person to perform the behaviors they do in the physical world. James was influenced by Emanuel Swedenborg, who first introduced him to this idea. James stated that, although it does appear that humans use associations to move from one event to the next, this cannot be done without this soul tying everything together. For, after an association has been made, it is the person who decides which part of it to focus on, and therefore determines in which direction following associations will lead. Associationism is too simple in that it does not account for decision-making of future behaviors, and memory of what worked well and what did not. Spiritualism, however, does not demonstrate actual physical representations for how associations occur. James combined the views of spiritualism and associationism to create his own way of thinking. James discussed tender-minded thinkers as religious, optimistic, dogmatic, and monistic. Tough-minded thinkers were irreligious, pessimistic, pluralists, and skeptical. Healthy-minded individuals were seen as natural believers by having faith in God and universal order. People who focused on human miseries and suffering were noted as sick souls.

James was a founding member and vice president of the American Society for Psychical Research. The lending of his name made Leonora Piper a famous medium. In 1885, the year after the death of his young son, James had his first sitting with Piper at the suggestion of his mother-in-law. He was soon convinced that Piper knew things she could only have discovered by supernatural means. He expressed his belief in Piper by saying, "If you wish to upset the law that all crows are black, it is enough if you prove that one crow is white. My white crow is Mrs. Piper." However, James did not believe that Piper was in contact with spirits. After evaluating sixty-nine reports of Piper's mediumship he considered the hypothesis of telepathy as well as Piper obtaining information about her sitters by natural means such as her memory recalling information. According to James the "spirit-control" hypothesis of her mediumship was incoherent, irrelevant and in cases demonstrably false.

James held séances with Piper and was impressed by some of the details he was given; however, according to Massimo Polidoro a maid in the household of James was friendly with a maid in Piper's house and this may have been a source of information that Piper used for private details about James. Bibliographers Frederick Burkhardt and Fredson Bowers who compiled the works of James wrote "It is thus possible that Mrs. Piper's knowledge of the James family was acquired from the gossip of servants and that the whole mystery rests on the failure of the people upstairs to realize that servants [downstairs] also have ears."

James was convinced that the "future will corroborate" the existence of telepathy. Psychologists such as James McKeen Cattell and Edward B. Titchener took issue with James's support for psychical research and considered his statements unscientific. Cattell in a letter to James wrote that the "Society for Psychical Research is doing much to injure psychology".

James's theory of the self

James's theory of the self divided a person's mental picture of self into two categories: the "Me" and the "I". The "Me" can be thought of as a separate object or individual a person refers to when describing their personal experiences; while the "I" is the self that knows who they are and what they have done in their life. Both concepts are depicted in the statement; "I know it was me who ate the cookie." He called the "Me" part of self the "empirical me" and the "I" part "the pure Ego". For James, the "I" part of self was the thinking self, which could not be further divided. He linked this part of the self to the soul of a person, or what is now thought of as the mind. Educational theorists have been inspired in various ways by James's theory of self, and have developed various applications to curricular and pedagogical theory and practice.

James further divided the "Me" part of self into: a material, a social, and a spiritual self, as below.

Material self

The material self consists of things that belong to a person or entities that a person belongs to. Thus, things like the body, family, clothes, money, and such make up the material self. For James, the core of the material self was the body. Second to the body, James felt a person's clothes were important to the material self. He believed a person's clothes were one way they expressed who they felt they were; or clothes were a way to show status, thus contributing to forming and maintaining one's self-image. Money and family are critical parts of the material self. James felt that if one lost a family member, a part of who they are was lost also. Money figured in one's material self in a similar way. If a person had significant money then lost it, who they were as a person changed as well.

Social self

Our social selves are who we are in a given social situation. For James, people change how they act depending on the social situation that they are in. James believed that people had as many social selves as they did social situations they participated in. For example, a person may act in a different way at work when compared to how that same person may act when they are out with a group of friends. James also believed that in a given social group, an individual's social self may be divided even further. An example of this would be, in the social context of an individual's work environment, the difference in behavior when that individual is interacting with their boss versus their behavior when interacting with a co-worker.

Spiritual self

For James, the spiritual self was who we are at our core. It is more concrete or permanent than the other two selves. The spiritual self is our subjective and most intimate self. Aspects of a spiritual self include things like personality, core values, and conscience that do not typically change throughout an individual's lifetime. The spiritual self involves introspection, or looking inward to deeper spiritual, moral, or intellectual questions without the influence of objective thoughts. For James, achieving a high level of understanding of who we are at our core, or understanding our spiritual selves is more rewarding than satisfying the needs of the social and material selves.

Pure ego

What James refers to as the "I" self. For James, the pure ego is what provides the thread of continuity between our past, present, and future selves. The pure ego's perception of consistent individual identity arises from a continuous stream of consciousness. James believed that the pure ego was similar to what we think of as the soul, or the mind. The pure ego was not a substance and therefore could not be examined by science.

Notable works

Collections

Psychology: Briefer Course (rev. and condensed Principles of Psychology), The Will to Believe and Other Essays in Popular Philosophy, Talks to Teachers and Students, Essays (nine others)
The Varieties of Religious Experience, Pragmatism, A Pluralistic Universe, The Meaning of Truth, Some Problems of Philosophy, Essays
  • The Writings of William James: A Comprehensive Edition (1978). University of Chicago Press, 912 pp., ISBN 0-226-39188-4
Pragmatism, Essays in Radical Empiricism, and A Pluralistic Universe complete; plus selections from other works
  • In 1975, Harvard University Press began publication of a standard edition of The Works of William James.

Neuromodulation (medicine)

From Wikipedia, the free encyclopedia

Neuromodulation is "the alteration of nerve activity through targeted delivery of a stimulus, such as electrical stimulation or chemical agents, to specific neurological sites in the body". It is carried out to normalize – or modulate – nervous tissue function. Neuromodulation is an evolving therapy that can involve a range of electromagnetic stimuli such as a magnetic field (rTMS), an electric current, or a drug instilled directly in the subdural space (intrathecal drug delivery). Emerging applications involve targeted introduction of genes or gene regulators and light (optogenetics), and by 2014, these had been at minimum demonstrated in mammalian models, or first-in-human data had been acquired. The most clinical experience has been with electrical stimulation.

Neuromodulation, whether electrical or magnetic, employs the body's natural biological response by stimulating nerve cell activity that can influence populations of nerves by releasing transmitters, such as dopamine, or other chemical messengers such as the peptide Substance P, that can modulate the excitability and firing patterns of neural circuits. There may also be more direct electrophysiological effects on neural membranes as the mechanism of action of electrical interaction with neural elements. The end effect is a "normalization" of a neural network function from its perturbed state. Presumed mechanisms of action for neurostimulation include depolarizing blockade, stochastic normalization of neural firing, axonal blockade, reduction of neural firing keratosis, and suppression of neural network oscillations. Although the exact mechanisms of neurostimulation are not known, the empirical effectiveness has led to considerable application clinically.

Existing and emerging neuromodulation treatments also include application in medication-resistant epilepsy, chronic head pain conditions, and functional therapy ranging from bladder and bowel or respiratory control to improvement of sensory deficits, such as hearing (cochlear implants and auditory brainstem implants) and vision (retinal implants). Technical improvements include a trend toward minimally invasive (or noninvasive) systems; as well as smaller, more sophisticated devices that may have automated feedback control, and conditional compatibility with magnetic resonance imaging.

Neuromodulation therapy has been investigated for other chronic conditions, such as Alzheimer's disease, depression, chronic pain, and as an adjunctive treatment in recovery from stroke.

Invasive electrical neuromodulation methods

Electrical stimulation using implantable devices came into modern usage in the 1980s and its techniques and applications have continued to develop and expand. These are methods where an operation is required to position an electrode. The stimulator, with the battery, similar to a pacemaker, may also be implanted, or may remain outside the body.

In general, neuromodulation systems deliver electrical currents and typically consist of the following components: An epidural, subdural or parenchymal electrode placed via minimally invasive needle techniques (so-called percutaneous leads) or an open surgical exposure to the target (surgical "paddle" or "grid" electrodes), or stereotactic implants for the central nervous system, and an implanted pulse generator (IPG). Depending on the distance from the electrode access point an extension cable may also be added into the system. The IPG can have either a non-rechargeable battery needing replacement every 2–5 years (depending on stimulation parameters) or a rechargeable battery that is replenished via an external inductive charging system.

Although most systems operate via delivery of a constant train of stimulation, there is now the advent of so-called "feed-forward" stimulation where the device's activation is contingent on a physiological event, such as an epileptic seizure. In this circumstance, the device is activated and delivers a desynchronizing pulse to the cortical area that is undergoing an epileptic seizure. This concept of feed-forward stimulation will likely become more prevalent as physiological markers of targeted diseases and neural disorders are discovered and verified. The on-demand stimulation may contribute to longer battery life, if sensing and signal-processing demands of the system are sufficiently power-efficient. New electrode designs could yield more efficient and precise stimulation, requiring less current and minimizing unwanted side-stimulation. In addition, to overcome the challenge of preventing lead migration in areas of the body that are subject to motion such as turning and bending, researchers are exploring developing small stimulation systems that are recharged wirelessly rather than through an electrical lead.

Spinal cord stimulation

Spinal cord stimulation is a form of invasive neuromodulation therapy in common use since the 1980s. Its principal use is as a reversible, non-pharmacological therapy for chronic pain management that delivers mild electrical pulses to the spinal cord. In patients who experience pain reduction of 50 percent or more during a temporary trial, a permanent implant may be offered in which, as with a cardiac pacemaker, an implantable pulse generator about the size of a stopwatch is placed under the skin on the trunk. It delivers mild impulses along slender electrical leads leading to small electrical contacts, about the size of a grain of rice, at the area of the spine to be stimulated.

Stimulation is typically in the 20–200 Hz range, though a novel class of stimulation parameters are now emerging that employ a 10 kHz stimulation train as well as 500 Hz "burst stimulation". Kilohertz stimulation trains have been applied to both the spinal cord proper as well as the dorsal root ganglion in humans. All forms of spinal cord stimulation have been shown to have varying degrees of efficacy to address a variety of pharmacoresistant neuropathic or mixed (neuropathic and noiciceptive) pain syndromes such as post-laminectomy syndrome, low back pain, complex regional pain syndrome, peripheral neuropathy, peripheral vascular disease and angina.

The general process for spinal cord stimulation involves a temporary trailing of appropriate patients with an external pulse generator attached to epidural electrodes located in the lower thoracic spinal cord. The electrodes are placed either via a minimally invasive needle technique (so-called percutaneous leads) or an open surgical exposure (surgical "paddle" electrodes).

Patient selection is key, and candidates should pass rigorous psychological screening as well as a medical workup to assure that their pain syndrome is truly medication-resistant. After recuperating from the implant procedure, the patient will return to have the system turned on and programmed. Depending on the system, the program may elicit a tingling sensation that covers most of the painful area, replacing some of the painful sensations with more of a gentle massaging sensation, although other more recent systems do not create a tingling sensation. The patient is sent home with a handheld remote controller to turn the system off or on or switch between pre-set stimulation parameters, and can follow up to adjust the parameters.

Deep brain stimulation

Another invasive neuromodulation treatment developed in the 1980s is deep brain stimulation, which may be used to help limit symptoms of movement disorder in Parkinson's disease, dystonia, or essential tremor. Deep brain stimulation was approved by the U.S. Food and Drug Administration in 1997 for essential tremor, in 2002 for Parkinson's disease, and received a humanitarian device exemption from the FDA in 2003 for motor symptoms of dystonia. It was approved in 2010 in Europe for the treatment of certain types of severe epilepsy. DBS also has shown promise, although still in research, for medically intractable psychiatric syndromes of depression, obsessive compulsive disorders, intractable rage, dementia, and morbid obesity. It has also shown promise for Tourette syndrome, torticollis, and tardive dyskinesia. DBS therapy, unlike spinal cord stimulation, has a variety of central nervous system targets, depending on the target pathology. For Parkinson's disease central nervous system targets include the subthalamic nucleus, globus pallidus interna, and the ventral intermidus nucleus of the thalamus. Dystonias are often treated by implants targeting globus pallidus interna, or less often, parts of the ventral thalamic group. The anterior thalamus is the target for epilepsy.

DBS research targets include, but are not limited to the following areas: Cg25 for depression, the anterior limb of the internal capsule for depression as well as obsessive compulsive disorder (OCD), centromedian/parafasicularis, centromedian thalamic nuclei and the subthalamic nucleus for OCD, anorexia and Tourette syndrome, the nucleus accumbens and ventral striatum have also been assayed for depression and pain.

Other invasive electrical methods

Non-invasive electrical methods

These methods use external electrodes to apply a current to the body in order to change the functioning of the nervous system.

Methods include:

Non-invasive magnetic methods

Magnetic methods of neuromodulation are normally non-invasive: no surgery is required to allow a magnetic field to enter the body because the magnetic permeability of tissue is similar to that of air. In other words: magnetic fields penetrate the body very easily.

The two main techniques are highly related in that both use changes in magnetic field strength to induce electric fields and ionic currents in the body. There are however differences in approach and hardware. In rTMS the stimulation has a high amplitude (0.5–3 tesla), a low complexity and anatomical specificity is reached through a highly focal magnetic field. In tPEMF the stimulation has a low amplitude (0.01–500 millitesla), a high complexity and anatomical specificity is reached through the specific frequency content of the signal.

Invasive chemical methods

Chemical neuromodulation is always invasive, because a drug is delivered in a highly specific location of the body. The non-invasive variant is traditional pharmacotherapy, e.g. swallowing a tablet.

  • Intrathecal drug delivery systems (ITDS, which may deliver micro-doses of painkiller (for instance, ziconotide) or anti-spasm medicine (such as baclofen) directly to the site of action)

History

Electrical stimulation of the nervous system has a long and complex history. Earlier practitioners of deep brain stimulation in the latter half of the 20th century (Delgado, Heath, Hosbuchi. See Hariz et al. for historical review) were limited by the technology available. Heath, in the 1950s, stimulated subcortical areas and made detailed observations of behavioral changes. A new understanding of pain perception was ushered in in 1965, with the Gate Theory of Wall and Melzack. Although now considered oversimplified, the theory held that pain transmissions from small nerve fibers can be overridden, or the gate "closed", by competing transmissions along the wider touch nerve fibers. Building on that concept, in 1967, the first dorsal column stimulator for pain control was demonstrated by Dr. Norm Shealy at Western Reserve Medical School, using a design adapted by Tom Mortimer, a graduate student at Case Institute of Technology, from cardiac nerve stimulators by Medtronic, Inc., where he had a professional acquaintance who shared the circuit diagram. In 1973, Hosbuchi reported alleviating the denervation facial pain of anesthesia dolorosa through ongoing electrical stimulation of the somatosensory thalamus, marking the start of the age of deep brain stimulation.

Despite the limited clinical experience in these decades, that era is remarkable for the demonstration of the role technology has in neuromodulation, and there are some case reports of deep brain stimulation for a variety of problems; real or perceived. Delgado hinted at the power of neuromodulation with his implants in the bovine septal region and the ability of electrical stimulation to blunt or alter behavior. Further attempts at this "behavioral modification" in humans were difficult and seldom reliable, and contributed to the overall lack of progress in central nervous system neuromodulation from that era. Attempts at intractable pain syndromes were met with more success, but again hampered by the quality of technology. In particular, the so-called DBS "zero" electrode, (consisting of a contact loop on its end) had an unacceptable failure rate and revisions were fraught with more risk than benefit. Overall, attempts at using electrical stimulation for "behavioral modification" were difficult and seldom reliable, slowing development of DBS. Attempts at addressing intractable pain syndromes with DBS were met with more success, but again hampered by the quality of technology. A number of physicians who hoped to address hitherto intractable problems sought development of more specialized equipment; for instance, in the 1960s, Wall's colleague Bill Sweet recruited engineer Roger Avery to make an implantable peripheral nerve stimulator. Avery started the Avery Company, which made a number of implantable stimulators. Shortly before his retirement in 1983, he submitted data requested by the FDA, which had begun to regulate medical devices following a 1977 meeting on the topic, regarding DBS for chronic pain. Medtronic and Neuromed also made deep brain stimulators at the time, but reportedly felt a complex safety and efficacy clinical trial in patients who were difficult to evaluate would be too costly for the size of the potential patient base, so did not submit clinical data on DBS for chronic pain to the FDA, and that indication was de-approved.

However, near this time in France and elsewhere, DBS was investigated as a substitute for lesioning of brain nuclei to control motor symptoms of movement disorders such as Parkinson's disease, and by the mid-1990s, this reversible, non-destructive stimulation therapy had become the primary application of DBS in appropriate patients, to slow progression of movement impairment from the disease and reduce side effects from long-term, escalating medication use.

In parallel to the development of neuromodulation systems to address motor impairment, cochlear implants were the first neuromodulation system to reach a broad commercial stage to address a functional deficit; they provide sound perception in users who are hearing-impaired due to missing or damaged sensory cells (cilia) in the inner ear. The approach to electrical stimulation used in cochlear implants was soon modified by one manufacturer, Boston Scientific Corporation, for design of electrical leads to be used in spinal cord stimulation treatment of chronic pain conditions.

Relationship to electroceuticals

In 2012, the global pharmaceutical company GlaxoSmithKline announced an initiative in bioelectric medicine in which the autonomic nervous system's impact on the immune system and inflammatory disease might be treated through electrical stimulation rather than pharmaceutical agents. The company's first investment in 2013 involved a small startup company, SetPoint Medical, which was developing neurostimulators to address inflammatory autoimmune disorders such as rheumatoid arthritis.

Ultimately, the electroceuticals quest aims to find the electro-neural signature of disease and at a cellular level, in real time, play back the more normal electro-signature to help maintain the neural signature in the normal state. Unlike preceding neuromodulation therapy methods, the approach would not involve electrical leads stimulating large nerves or spinal cords or brain centers. It might involve methods that are emerging within the neuromodulation family of therapies, such as optogenetics or some new nanotechnology. Disease states and conditions that have been discussed as targets for future electroceutical therapy include diabetes, infertility, obesity, rheumatoid arthritis, and autoimmune disorders.

The Conscious Mind

From Wikipedia, the free encyclopedia
 
The Conscious Mind: In Search of a Fundamental Theory
The Conscious Mind.gif
Cover
AuthorDavid Chalmers
CountryUnited States
LanguageEnglish
SubjectPhilosophy of mind
PublisherOxford University Press
Publication date
1996
Media typePrint (hardcover and paperback)
Pages432
ISBN978-0195117899

The Conscious Mind: In Search of a Fundamental Theory was published in 1996, and is the first book written by David Chalmers, an Australian philosopher specialising in philosophy of mind. Although the book has been greatly influential, Chalmers maintains that it is "far from perfect", as most of it was written as part of his PhD dissertation after "studying philosophy for only four years".

Summary

Thesis

In The Conscious Mind Chalmers argues that (1) the physical does not exhaust the actual, so materialism is false; (2) consciousness is a fundamental fact of nature; (3) science and philosophy should strive towards discovering a fundamental law of consciousness.

Definitions

  • psychological consciousness: publicly accessible descriptions of consciousness, such as its neurochemical correlates or role in influencing behaviour.
  • phenomenal consciousness: experience; something is phenomenologically conscious if it feels like something to be it.

Every mental state can be described in psychological terms, phenomenological terms, or both.

Further clarification

Psychological and phenomenal consciousness are often conflated. Thinkers may purport to have solved consciousness (in the phenomenological sense) when really all they have solved are certain aspects of psychological consciousness. To use Chalmers words: they claim to have solved the "hard problem of consciousness", when really all they have solved are certain "easy problems of consciousness".

Chalmers believes that an adequate theory of consciousness can only come by solving both the hard and easy problems. On top of discovering brain states associated with conscious experience, science must also discover why and how certain brain states are accompanied by experience. This is what Chalmers attempts to do in The Conscious Mind.

Arguments against reductionism

The hard problem is hard, by Chalmers account, because conscious experience is irreducible to lower order physical facts. He supports this conclusion with three main lines of argument, which are summarised below.

Inverted qualia
  1. Appeals to Conceivability: Chalmers argues that conscious experience can always be "abstracted away" from reductive explanations. This is evidenced by the conceivability and, by extension, logical possibility of philosophical zombies (exact replicas of a person that lack conscious experience). Alternatively, it is conceivable that a "partial zombie" could have been "physically identical", but not "phenomenological identical" to their nonzombie twin (they could have an inverted visible spectrum, for instance).
  2. Appeals to Epistemology: Unlike other forms of knowledge, knowledge of consciousness can only ever be gained through first hand experience. The problem of other minds is evidence of this. Frank Jackson's famous thought experiment Mary's Room demonstrates a similar point. Upon seeing red, Mary gains new information was not entailed by the physical facts alone.
  3. Appeals to Analysis: There are no satisfying reductive accounts of consciousness, and it is not even clear what such a theory would look like. All such accounts suffer from the same core sin: the inability to explain why certain brain states are accompanied by conscious experience.

The conclusion of all these arguments is the same: consciousness is irreducible to physical facts alone.

Against materialism

The only things that are irreducible to lower level facts are fundamental laws of nature (e.g., space and time). Since consciousness is irreducible, Chalmers believes that it, too, is fundamental.

Chalmers accepts that people may be reluctant to accept this conclusion, but notes that people were initially reluctant to accept the fundamental nature of electromagnetism as well. He also accepts that his conclusion sound jarring, but notes that the brute nature of consciousness poses no more a mystery than the brute nature of electromagnetism, gravity, or any other fundamental law.

Constraints

So, just as scientists of the past have sought fundamental laws of gravity and electromagnetism, so too should scientists of the present seek fundamental laws of consciousness. So, after providing the disclaimer that he is "most likely to be entirely wrong", Chalmers puts forward possible ways in which the search for a theory may be constrained:

  • Phenomenal Judgements: A theory of consciousness should be able to dispel epiphenominalism without resorting to interactionism (a view which Chalmers rejects).
  • The Double-Aspect Principle: Some information must be realised both physically and phenomenologically (i.e., realised both in the mind and brain). 
  • Structural Coherence: the internal structure of consciousness (structural relations between qualia, such as the red/green blue/yellow axis of colour vision) must be accounted for.
  • The Principle of Organisational Invariance: Through the thought experiments of Fading Qualia and Dancing Qualia. Chalmers concludes that consciousness and its contents are substrate independent; structurally isomorphic computations must create qualitatively identical experiences regardless of how they are realised.

Similarly, Chalmers puts forward a number of "open questions" that a fundamental theory must answer:

  • Why does certain information correspond to certain qualia rather than functionally equivalent qualia?
  • What are the relations between spatial representations in the mind and the structure of space itself?
  • How do the structures of our sensory and neurological apparatus influence the structure of consciousness?
  • What causes the unification of consciousness?
  • Why are some bits of information realised in experience while others are not.

Good contenders for a fundamental theory of consciousness would be one that (a) fits the above criteria; (b) is compatible with the data; (c) has predicative power; and (c) is elegant. Though, of course, there will likely be further considerations that arise as science progresses.

Speculation

Chalmers explores a number of possibilities. Chalmers believes that information will invariably play a central role in any theory of consciousness. However, Chalmers is unsure whether or not information will ultimately play a conceptual role or an ontological one. Chalmers further constraints the role of information by concluding that it must only be phenomenally realised it is physically realised; in other words, the information system must be active (otherwise a computer that's turned off may qualia). So causation may also play a role.

Interestingly, this account of consciousness has predictive power within the realm of quantum theory. Namely, it addresses objections made by the physicist Roger Penrose regarding the many worlds interpretation of quantum mechanics:

I do not see why a conscious being need be aware of only "one" of the alternatives in a linear superposition. What is it about consciousnesses that says that consciousness must not be "aware" of that tantalising linear combination of both a dead and a live cat? It seems to me that a theory of consciousness would be needed for one to square the many world view with what one actually observes.

Chalmers' earlier account of consciousness is such a theory. This leaves the many-world view undoubtedly the most elegant of all interpretations of quantum mechanics (from a mathematical standpoint), albeit a counterintuitive one.

Reception

The Conscious Mind has had significant influence on philosophy of mind and the scientific study of consciousness, as is evidenced by Chalmers easy/hard problem distinction having become standard terminology within relevant philosophical and scientific fields. Chalmers has expressed bewilderment at the book's success, writing that it has "received far more attention than I reasonably could have expected."

Praise

David Lewis is a proponent of materialism whose views are criticised numerous times throughout The Conscious Mind. Despite this, Lewis praises Chalmers for his understanding of the issue and for leaving his critics with "few points to make" that Chalmers "hasn't made already". Lewis has characterised The Conscious Mind as "exceptionally ambitious and exceptionally successful", considering it "the best book in philosophy of mind for many years."

Steven Pinker has hailed The Conscious Mind as an "outstanding contribution" to consciousness studies, stating that Chalmers argued his thesis "with impeccable clarity and rigor".

Criticism

Patricia and Paul Churchland have criticised Chalmers claim that everything but consciousness logically supervenes on the physical, and that such failures of supervenience mean that materialism must be false. Heat and luminescence, for instance, are both physical properties that logically supervene on the physical. Others have questioned the premise that a priori entailment is required for logical supervenience.

Daniel Dennett has labelled Chalmers a "reactionary", and calls the invocation of philosophical zombies "an embarrassment". By his account, the thought experiment hinges on a "hunch" and begs the question. He argues that the mysterious nature of consciousness amounts to nothing more than a cognitive illusion, and that philosophers ought to drop "the zombie like a hot potato".

Chalmers responds to critics in his 2010 book The Character of Consciousness and on his website.

Book reviews

The Conscious Mind has been reviewed in journals such as Foundations of Physics, Psychological Medicine, Mind, The Journal of Mind and Behavior, and Australian Review of Books. The book was described by The Sunday Times as "one of the best science books of the year."

Global workspace theory

From Wikipedia, the free encyclopedia

Global workspace theory (GWT) is a simple cognitive architecture that has been developed to account qualitatively for a large set of matched pairs of conscious and unconscious processes. It was proposed by Bernard Baars (1988, 1997, 2002). Brain interpretations and computational simulations of GWT are the focus of current research.

GWT resembles the concept of working memory, and is proposed to correspond to a "momentarily active, subjectively experienced" event in working memory (WM)—the "inner domain in which we can rehearse telephone numbers to ourselves or in which we carry on the narrative of our lives. It is usually thought to include inner speech and visual imagery." (in Baars, 1997).

The theater metaphor

GWT can be explained in terms of a "theater metaphor". In the "theater of consciousness" a "spotlight of selective attention" shines a bright spot on stage. The bright spot reveals the contents of consciousness, actors moving in and out, making speeches or interacting with each other. The audience is not lit up—it is in the dark (i.e., unconscious) watching the play. Behind the scenes, also in the dark, are the director (executive processes), stage hands, script writers, scene designers and the like. They shape the visible activities in the bright spot, but are themselves invisible. Baars argues that this is distinct from the concept of the Cartesian theater, since it is not based on the implicit dualistic assumption of "someone" viewing the theater, and is not located in a single place in the mind (in Blackmore, 2005).

The model

GWT involves a fleeting memory with a duration of a few seconds (much shorter than the 10–30 seconds of classical working memory). GWT contents are proposed to correspond to what we are conscious of, and are broadcast to a multitude of unconscious cognitive brain processes, which may be called receiving processes. Other unconscious processes, operating in parallel with limited communication between them, can form coalitions which can act as input processes to the global workspace. Since globally broadcast messages can evoke actions in receiving processes throughout the brain, the global workspace may be used to exercise executive control to perform voluntary actions. Individual as well as allied processes compete for access to the global workspace, striving to disseminate their messages to all other processes in an effort to recruit more cohorts and thereby increase the likelihood of achieving their goals. Incoming stimuli need to be stored temporarily in order to be able to compete for attention and conscious access. Kouider and Dehaene predicted the existence of a sensory memory buffer that maintains stimuli for "a few hundreds of milliseconds." Recent research offers preliminary evidence for such a buffer store and indicates a gradual but rapid decay with extraction of meaningful information severely impaired after 300 ms and most data being completely lost after 700 ms.

Baars (1997) suggests that the global workspace "is closely related to conscious experience, though not identical to it." Conscious events may involve more necessary conditions, such as interacting with a "self" system, and an executive interpreter in the brain, such as has been suggested by a number of authors including Michael S. Gazzaniga.

Nevertheless, GWT can successfully model a number of characteristics of consciousness, such as its role in handling novel situations, its limited capacity, its sequential nature, and its ability to trigger a vast range of unconscious brain processes. Moreover, GWT lends itself well to computational modeling. Stan Franklin's IDA model is one such computational implementation of GWT. See also Dehaene et al. (2003), Shanahan (2006) and Bao (2020).

GWT also specifies "behind the scenes" contextual systems, which shape conscious contents without ever becoming conscious, such as the dorsal cortical stream of the visual system. This architectural approach leads to specific neural hypotheses. Sensory events in different modalities may compete with each other for consciousness if their contents are incompatible. For example, the audio and video track of a movie will compete rather than fuse if the two tracks are out of sync by more than 100 ms., approximately. The 100 ms time domain corresponds closely with the known brain physiology of consciousness, including brain rhythms in the alpha-theta-gamma domain, and event-related potentials in the 200-300 ms domain.

However, much of this research is based on studies of unconscious priming and recent studies show that many of the methods used for unconscious priming are flawed.

Global neuronal workspace

Stanislas Dehaene extended the global workspace with the "neuronal avalanche" showing how sensory information gets selected to be broadcast throughout the cortex. Many brain regions, the prefrontal cortex, anterior temporal lobe, inferior parietal lobe, and the precuneus all send and receive numerous projections to and from a broad variety of distant brain regions, allowing the neurons there to integrate information over space and time. Multiple sensory modules can therefore converge onto a single coherent interpretation, for example, a "red sports car zooming by". This global interpretation is broadcast back to the global workspace creating the conditions for the emergence of a single state of consciousness, at once differentiated and integrated.

Alternatively, the theory of practopoiesis suggests that the global workspace is achieved in the brain primarily through fast adaptive mechanisms of nerve cells. According to that theory, connectivity does not matter much. Critical is rather the fact that neurons can rapidly adapt to the sensory context within which they operate. Notably, for achieving a global workspace, the theory presumes that these fast adaptive mechanisms have the capability to learn when and how to adapt.

Criticism

Susan Blackmore challenged the concept of stream of consciousness. "When I say that consciousness is an illusion I do not mean that consciousness does not exist. I mean that consciousness is not what it appears to be. If it seems to be a continuous stream of rich and detailed experiences, happening one after the other to a conscious person, this is the illusion." However, she also says that a good way to observe the "stream of consciousness" may be to calm the mind in meditation. The criticism is based on the stream of perception data from the senses rather than about consciousness itself. Also, it is not explained why some things are conscious at all. Suggestions have also been made regarding the importance of separating "two levels of analyses" when attempting to understand the "stream of consciousness".

Baars is in agreement with these points. The continuity of the "stream of consciousness" may in fact be illusory, just as the continuity of a movie is illusory. Nevertheless, the seriality of mutually incompatible conscious events is well supported by objective research over some two centuries of experimental work. A simple illustration would be to try to be conscious of two interpretations of an ambiguous figure or word at the same time. When timing is precisely controlled, as in the case of the audio and video tracks of the same movie, seriality appears to be compulsory for potentially conscious events presented within the same 100 ms interval.

J. W. Dalton has criticized the global workspace theory on the grounds that it provides, at best, an account of the cognitive function of consciousness, and fails even to address the deeper problem of its nature, of what consciousness is, and of how any mental process whatsoever can be conscious: the so-called "hard problem of consciousness". A. C. Elitzur has argued, however, "While this hypothesis does not address the 'hard problem', namely, the very nature of consciousness, it constrains any theory that attempts to do so and provides important insights into the relation between consciousness and cognition.", as much as any consciousness theory is constrained by the natural brain perception limitations.

New work by Richard Robinson shows promise in establishing the brain functions involved in this model and may help shed light on how we understand signs or symbols and reference these to our semiotic registers.

Introduction to entropy

From Wikipedia, the free encyclopedia https://en.wikipedia.org/wiki/Introduct...