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Friday, October 31, 2025

Philosophy of psychedelics

From Wikipedia, the free encyclopedia

Indian philosophy

The Indian Yogi and scholar Patanjali in his Yoga sutras (4.1) mentions that mystic powers (siddhaya) can arise from certain "herbs" or "healing plants" (osadhi):

janmauṣadhi-mantra-tapaḥ samādhi jāḥ siddhayaḥ||
The mystic powers arise due to birth, herbs, mantras, the performance of austerity and samadhi.

Later commentators on the Yoga sutras like Vyasa mention elixirs of the asuras, and also state these herbal concoctions can be found in this world. Adi Shankara meanwhile refers to the Vedic drink Soma.

Vajrayana Buddhist Tantras mention the nectar "amrita" (literally "immortal", "deathless") which was drunk during rituals and which is associated in the tradition with 'spiritual intoxication'. A biography of the scholar Gampopa mentions how one of his teachers stated that "You can obtain Buddhahood: by taking a medicine pill which will make you immortal like the sun and moon." This is a reference to the Vajrayana practice of rasayana (Skt: "alchemy") to create certain potions or pills. According to M.L. Walter's study of Indo-Tibetan rasayana, ingestion of these substances were said to "strengthen the yogin and procure the siddhi for him, as well as bringing him to the final goal." According to Chogyam Trungpa (1939–1987), a modern teacher in the Kagyu tradition:

amrita... is used in conferring the second abhisheka, the secret abhisheka. This transmission dissolves the student's mind into the mind of the teacher of the lineage. In general, amrita is the principle of intoxicating extreme beliefs, belief in ego, and dissolving the boundary between confusion and sanity so that coemergence can be realized.

19th century

European literature such as Confessions of an English Opium-Eater by Thomas De Quincey (one of the first English commentators on Kant)[7] and Samuel Taylor Coleridge's "Kubla Khan" described the use and phenomenal character of mind-altering substances such as opium. De Quincey held that opium allowed one to access the earliest of memories and that therefore no memories were ever truly forgotten:

The minutest incidents of childhood, or forgotten scenes of later years, were often revived: I could not be said to recollect them; for if I had been told of them when waking, I should not have been able to acknowledge them as parts of my past experience. But placed as they were before me, in dreams like intuitions, and clothed in all their evanescent circumstances and accompanying feelings, I recognized them instantaneously […] I feel assured that there is no such thing as forgetting possible to the mind.

Jacques-Joseph Moreau, who reported his experiments with mental patients and drugs, believed that "the hashish experience was a way to gain insight into mental disease."

The French Poet Baudelaire wrote about the effects of hashish and opium in Les Paradis artificiels (1860) and theorized about how they could be used to allow the individual to reach "ideal" states of mind. Charles Baudelaire was member of the "Club des Hashischins", a Parisian literary group dedicated to the exploration of altered states of consciousness which included Jacques-Joseph Moreau and literary figures such as Victor Hugo, Alexandre Dumas, Gerard de Nerval, Honore de Balzac, and Theophile Gautier. Baudelaire's opinion of the drug was generally negative, believing that it weakened and dampened artistic capacities, the personal Will and even the very identity of the hashish eater. He compared it to suicide and a false happiness, and saw wine as the true intoxicant of the artists.

In the United States, The Hasheesh Eater (1857), an autobiographical book by Fitz Hugh Ludlow, became popular. Ludlow wrote that a marijuana user sought "the soul’s capacity for a broader being, deeper insight, grander views of Beauty, Truth and Good than she now gains through the chinks of her cell." The American William James was one of the first academic philosophers to write about the effects of hallucinogenic substances in his The Subjective Effects of Nitrous Oxide (1882) in which he writes that the gas can produce a "tremendously exciting sense of an intense metaphysical illumination. Truth lies open to the view in depth beneath depth of almost blinding evidence. The mind sees all logical relations of being with an apparent subtlety and instantaniety to which its normal consciousness offers no parallel". He goes on to say that the experience gave him the sense that the philosophy of Hegel was true. In his The Varieties of Religious Experience he likewise writes:

Nitrous oxide and ether, especially nitrous oxide … stimulate the mystical consciousness in an extraordinary degree. … [In] the nitrous oxide trance we have a genuine metaphysical revelation. … [Our] normal waking consciousness, rational consciousness as we call it, is but one special type of consciousness, whilst all about it, parted from it by the filmiest of screens, there lie potential forms of consciousness entirely different.

While it has been speculated that Friedrich Nietzsche had psychedelic experiences brought on by the drugs he used to help with his various illnesses, it is more likely that his drug use was restricted to opium, rather than classic psychedelics. He had, however, speculated on the significance of altered states, particularly with regards to "narcotics potions" taken to attain oneness with one's fellow man and with nature. In The Birth of Tragedy he wrote:

"Now that the gospel of universal harmony is sounded, each individual becomes not only reconciled to his fellow but actually at one with him - as though the veil of Maya had been torn apart and there remained only shreds floating before the vision of mystical Oneness."

20th century

After using mescaline in 1953, Aldous Huxley wrote The Doors of Perception where he advanced the theory that psychedelic compounds could produce mystical experiences and knowledge, "what the visionary, the medium, even the mystic were talking about" and what Eastern philosophy described with terms like satcitananda, godhead, suchness, shunyata, anatta and dharmakaya. Huxley also quotes the philosopher C. D. Broad, who held that the brain and nervous system might act as a reducing valve of all the stimuli in the universe:

According to such a theory, each one of us is potentially Mind at Large. But in so far as we are animals, our business is at all costs to survive. To make biological survival possible, Mind at Large has to be funneled through the reducing valve of the brain and nervous system. What comes out at the other end is a measly trickle of the kind of consciousness which will help us to stay alive on the surface of this Particular planet.

Huxley wrote that it was possible that certain human beings could, through drugs, meditation, etc. circumvent the reducing valve and experience something far beyond everyday consciousness. This experience Huxley saw as the source of all mysticism, a theory termed the perennial philosophy. He also discusses art and the legality of various drugs in the West as well as arguing for the importance for self-transcendence. Huxley's philosophical novel Island also described a utopian society that used a psychedelic substance for spiritual purposes.

In the early 1960s a group that eventually came to be called "Harvard Psychedelic Club" which included Timothy Leary, Huston Smith and Ram Dass administered psychedelics to Harvard students. The group experimented with psychedelics in experiments such as the Harvard Psilocybin Project. Huston Smith's last work, Cleansing the Doors of Perception, describes the Harvard Project in which he participated.

Ram Dass' Be Here Now and Timothy Leary's The Psychedelic Experience: A Manual Based on The Tibetan Book of the Dead compared the psychedelic experiences to Eastern philosophy and mystical states of consciousness. These books further popularized the idea that Eastern – particularly Indian – philosophical and spiritual insights could be obtained from using psychedelics. One of these experiences described in The Psychedelic Experience is that of ego death or depersonalization.

The idea that the psychedelic experience could grant access to eastern spiritual insights was also promoted by the popular philosopher Alan Watts in his writings such as The Joyous Cosmology, who also argued that one should not remain dependent on them for spiritual growth: "If you get the message, hang up the phone. For psychedelic drugs are simply instruments, like microscopes, telescopes, and telephones. The biologist does not sit with eye permanently glued to the microscope, he goes away and works on what he has seen."

Various psychologists during the 1960s also studied psychedelic substances and worked with psychedelic therapy and later developed various theories about their effects and significance. Stanislav Grof is known for his extensive work in LSD psychotherapy and for developing a theory which stated that the psychedelic experience allowed one to relive birth trauma and to explore the depths of the unconscious mind. Grof observed four levels of the LSD experience, which for him correspond to areas of the human unconscious: (1) abstract and aesthetic experiences (2) psychodynamic experiences (3) perinatal experiences, and (4) transpersonal experiences. Grof defined the last level as "experiences involving an expansion or extension of consciousness beyond the usual ego boundaries and beyond the limitations of time and/or space." The field of transpersonal psychology focuses on this type of experience. Grof included topics such as consciousness, mysticism and metaphysics in his later writings.

The scientist and philosopher John C. Lilly discussed his experiments with psychedelics and altered states of consciousness in The Center of the Cyclone: An Autobiography of Inner Space and Programming and Metaprogramming in the Human Biocomputer. Other psychologists who studied and wrote on psychedelic use include Walter Pahnke, Ralph Metzner and Claudio Naranjo.

According to writer James Oroc, the 1990s brought about a second phase in modern psychedelic culture. The philosophical foundation of this new wave of psychedelic thought was based on the works of Alexander Shulgin, Alex Grey and Terence McKenna.

Contemporary

Academic

Neuroscientist Rick Strassman has written about his research into the psychedelic N,N-Dimethyltryptamine in his book DMT: The Spirit Molecule (2001). In his book Strassman investigates the possible connection between natural DMT in mystical and Near Death Experiences and psychedelic states caused by outwardly administered DMT. He also describes the psychedelic experiences of the volunteers in his experiments and their encounter with certain strange "beings" after being administered DMT.

The philosopher Thomas Metzinger has discussed the effects of substances such as LSD, dimethyltryptamine, and mescaline in his Being No One (2003) and those of psilocybin in The Ego Tunnel (2009). Metzinger describes the hallucinatory component of the psychedelic experience as "epistemically vacuous," i.e., not a reliable source of knowledge.

In 2012, University of California Press published the book Neuropsychedelia by anthropologist Nicolas Langlitz. In this book, Langlitz recounts the findings of his fieldwork following scientists involved in reviving scientific research on psychedelics as well as his own philosophical reflections. He explains that Aldous Huxley's view expressed in The Doors of Perception—of the brain as a "reducing valve" which when released by the ingestion of a psychedelics produces a "perennial" mystical experience—has been very influential among contemporary psychopharmacologists. These scientists, Langlitz writes, have given Huxley's view a materialist "neurobiological reinterpretation" which Langlitz calls "mystic materialism".

In 2021, the philosopher Chris Letheby's book Philosophy of Psychedelics was published by Oxford University PressPhilosophy of Psychedelics is organised as a defence against what Letheby calls the "Comforting Delusion Objection" to psychedelic therapy. The objection is that psychedelic therapy works by inducing non-naturalistic metaphysical beliefs, and so it is epistemically deficient if one adopts a philosophically naturalistic world-view. Letheby concludes that the Comforting Delusion Objection fails, and that the epistemic status of psychedelic therapy, given philosophical naturalism, is good.

In 2022, Christine Hauskeller and Peter Sjöstedt-Hughes' edited volume, Philosophy and Psychedelics: Frameworks for Exceptional Experience was published by Bloomsbury Academic.

Other contemporary academics writing on the philosophy of psychedelics include Sarah Lane Ritchie, Aidan Lyon, and Anya Farennikova.

In his non-academic encyclopedia of psychedelic culture and thought Psychedelia (2012), Patrick Lundborg developed a psychedelic philosophy he called "Unified Psychedelic Theory" (UPT) which draws from Platonism, the phenomenology of Husserl and Merleau-Ponty, Paul D. MacLean's Triune brain theory, the work of Eugen Fink, and other thinkers.

The American author Sam Harris discussed his use of psychedelics in his 2014 book Waking Up: A Guide to Spirituality Without Religion, which argues for a naturalized spirituality.

The philosopher Peter Sjöstedt-Hughes' book Noumenautics was published by the independent publisher Psychedelic Press in 2015 and discusses psychedelic phenomenology and its metaphysical implications. In 2021 they published his Modes of Sentience covering similar themes.

Four-dimensionalism

From Wikipedia, the free encyclopedia
https://en.wikipedia.org/wiki/Four-dimensionalism

In philosophy, four-dimensionalism (also known as the doctrine of temporal parts) is the ontological position that an object's persistence through time is like its extension through space. Thus, an object that exists in time has temporal parts in the various subregions of the total region of time it occupies, just like an object that exists in a region of space has at least one part in every subregion of that space.

Four-dimensionalists typically argue for treating time as analogous to space, usually leading them to endorse the doctrine of eternalism. This is a philosophical approach to the ontological nature of time, according to which all points in time are equally "real", as opposed to the presentist idea that only the present is real. As some eternalists argue by analogy, just as all spatially distant objects and events are as real as those close to us, temporally distant objects and events are as real as those currently present to us.

Perdurantism—or perdurance theory—is a closely related philosophical theory of persistence and identity, according to which an individual has distinct temporal parts throughout its existence, and the persisting object is the sum or set of all of its temporal parts. This sum or set is colloquially referred to as a "space-time worm", which has earned the perdurantist view the moniker of "the worm view". While all perdurantists are plausibly considered four dimensionalists, at least one variety of four dimensionalism does not count as perdurantist in nature. This variety, known as exdurantism or the "stage view", is closely akin to the perdurantist position. They also countenance a view of persisting objects that have temporal parts that succeed one another through time. However, instead of identifying the persisting object as the entire set or sum of its temporal parts, the exdurantist argues that any object under discussion is a single stage (time-slice, temporal part, etc.), and that the other stages or parts that comprise the persisting object are related to that part by a "temporal counterpart" relation.

Though they have often been conflated, eternalism is a theory of what time is like and what times exist, while perdurantism is a theory about persisting objects and their identity conditions over time. Eternalism and perdurantism tend to be discussed together because many philosophers argue for a combination of eternalism and perdurantism. Sider (1997) uses the term four-dimensionalism to refer to perdurantism, but Michael Rea uses the term "four-dimensionalism" to mean the view that presentism is false as opposed to "perdurantism", the view that endurantism is false and persisting objects have temporal parts.

Four-dimensionalism about material objects

Four-dimensionalism is a name for different positions. One of these uses four-dimensionalism as a position of material objects with respect to dimensions. Four-dimensionalism is the view that in addition to spatial parts, objects have temporal parts.

According to this view, four-dimensionalism cannot be used as a synonym for perdurantism. Perdurantists have to hold a four-dimensional view of material objects: it is impossible that perdurantists, who believe that objects persist by having different temporal parts at different times, do not believe in temporal parts. However, the reverse is not true. Four-dimensionalism is compatible with either perdurantism or exdurantism.

A-series and B-series

J.M.E. McTaggart in The Unreality of Time identified two descriptions of time, which he called the A-series and the B-series. The A-series identifies positions in time as past, present, or future, and thus assumes that the "present" has some objective reality, as in both presentism and the growing block universe. The B-series defines a given event as earlier or later than another event, but does not assume an objective present, as in four-dimensionalism. Much of the contemporary literature in the metaphysics of time has been taken to spring forth from this distinction, and thus takes McTaggart's work as its starting point.

Contrast with three-dimensionalism

Unlike the four dimensionalist, the three dimensionalist considers time to be a unique dimension that is not analogous to the three spatial dimensions: length, width and height. Whereas the four dimensionalist proposes that objects are extended across time, the three dimensionalist adheres to the belief that all objects are wholly present at any moment at which they exist. While the three dimensionalist agrees that the parts of an object can be differentiated based on their spatial dimensions, they do not believe an object can be differentiated into temporal parts across time. For example, in the three dimensionalist account, "Descartes in 1635" is the same object as "Descartes in 1620", and both are identical to Descartes, himself. However, the four dimensionalist considers these to be distinct temporal parts.

Prominent arguments in favor of four-dimensionalism

Several lines of argumentation have been advanced in favor of four-dimensionalism:

Firstly, four-dimensional accounts of time are argued to better explain paradoxes of change over time (often referred to as the paradox of the Ship of Theseus) than three-dimensional theories. A contemporary account of this paradox is introduced in Ney (2014), but the original problem has its roots in Greek antiquity. A typical Ship of Theseus paradox involves taking some changeable object with multiple material parts, for example a ship, then sequentially removing and replacing its parts until none of the original components are left. At each stage of the replacement, the ship is presumably identical with the original, since the replacement of a single part need not destroy the ship and create an entirely new one. But, it is also plausible that an object with none of the same material parts as another is not identical with the original object. So, how can an object survive the replacement of any of its parts, and in fact all of its parts? The four-dimensionalist can argue that the persisting object is a single space-time worm which has all the replacement stages as temporal parts, or in the case of the stage view that each succeeding stage bears a temporal counterpart relation to the original stage under discussion.

Secondly, problems of temporary intrinsics are argued to be best explained by four-dimensional views of time that involve temporal parts. As presented by David Lewis, the problem of temporary intrinsics involves properties of an object that are both had by that object regardless of how anything else in the world is (and thus intrinsic), and subject to change over time (thus temporary). Shape is argued to be one such property. So, if an object is capable of having a particular shape, and also changing its shape at another time, there must be some way for the same object to be, say, both round and square. Lewis argues that separate temporal parts having the incompatible properties best explains an object being able to change its shape in this way, because other accounts of three-dimensional time eliminate intrinsic properties by indexing them to times and making them relational instead of intrinsic.

Convergent evolution

From Wikipedia, the free encyclopedia
 
Two succulent plant genera, Euphorbia and Astrophytum, are only distantly related, but the species within each have converged on a similar body form 
 

Convergent evolution is the independent evolution of similar features in species of different periods or epochs in time. Convergent evolution creates analogous structures that have similar form or function but were not present in the last common ancestor of those groups. The cladistic term for the same phenomenon is homoplasy. The recurrent evolution of flight is a classic example, as flying insects, birds, pterosaurs, and bats have independently evolved the useful capacity of flight. Functionally similar features that have arisen through convergent evolution are analogous, whereas homologous structures or traits have a common origin but can have dissimilar functions. Bird, bat, and pterosaur wings are analogous structures, but their forelimbs are homologous, sharing an ancestral state despite serving different functions.

The opposite of convergent evolution is divergent evolution, where related species evolve different traits. Convergent evolution is similar to parallel evolution, which occurs when two independent species evolve in the same direction and thus independently acquire similar characteristics; for instance, gliding frogs have evolved in parallel from multiple types of tree frog.

Many instances of convergent evolution are known in plants, including the repeated development of C4 photosynthesis, seed dispersal by fleshy fruits adapted to be eaten by animals, and carnivory.

Overview

Homology and analogy in mammals and insects: on the horizontal axis, the structures are homologous in morphology, but different in function due to differences in habitat. On the vertical axis, the structures are analogous in function due to similar lifestyles but anatomically different with different phylogeny.

In morphology, analogous traits arise when different species live in similar ways and/or a similar environment, and so face the same environmental factors. When occupying similar ecological niches (that is, a distinctive way of life) similar problems can lead to similar solutions. The British anatomist Richard Owen was the first to identify the fundamental difference between analogies and homologies.

In biochemistry, physical and chemical constraints on mechanisms have caused some active site arrangements such as the catalytic triad to evolve independently in separate enzyme superfamilies.

In his 1989 book Wonderful Life, Stephen Jay Gould argued that if one could "rewind the tape of life [and] the same conditions were encountered again, evolution could take a very different course." Simon Conway Morris disputes this conclusion, arguing that convergence is a dominant force in evolution, and given that the same environmental and physical constraints are at work, life will inevitably evolve toward an "optimum" body plan, and at some point, evolution is bound to stumble upon intelligence, a trait presently identified with at least primates, corvids, and cetaceans.

Distinctions

Cladistics

In cladistics, a homoplasy is a trait shared by two or more taxa for any reason other than that they share a common ancestry. Taxa which do share ancestry are part of the same clade; cladistics seeks to arrange them according to their degree of relatedness to describe their phylogeny. Homoplastic traits caused by convergence are therefore, from the point of view of cladistics, confounding factors which could lead to an incorrect analysis.

Atavism

It can be difficult to tell whether a trait has been lost and then re-evolved convergently, or whether a gene has simply been switched off and then re-enabled later. Such a re-emerged trait is called an atavism. From a mathematical standpoint, an unused gene (selectively neutral) has a steadily decreasing probability of retaining potential functionality over time. The time scale of this process varies greatly in different phylogenies; in mammals and birds, there is a reasonable probability of a gene's remaining in the genome in a potentially functional state for around 6 million years.

Parallel vs. convergent evolution

Evolution at an amino acid position. In each case, the left-hand species changes from having alanine (A) at a specific position in a protein in a hypothetical ancestor, and now has serine (S) there. The right-hand species may undergo divergent, parallel, or convergent evolution at this amino acid position relative to the first species.

When two species are similar in a particular character, evolution is defined as parallel if the ancestors were also similar, and convergent if they were not. Some scientists have argued that there is a continuum between parallel and convergent evolution, while others maintain that despite some overlap, there are still important distinctions between the two.

When the ancestral forms are unspecified or unknown, or the range of traits considered is not clearly specified, the distinction between parallel and convergent evolution becomes more subjective. For instance, the striking example of similar placental and marsupial forms is described by Richard Dawkins in The Blind Watchmaker as a case of convergent evolution, because mammals on each continent had a long evolutionary history prior to the extinction of the dinosaurs under which to accumulate relevant differences.

At molecular level

Evolutionary convergence of serine and cysteine protease towards the same catalytic triads organisation of acid-base-nucleophile in different protease superfamilies. Shown are the triads of subtilisin, prolyl oligopeptidase, TEV protease, and papain.

Proteins

Tertiary structures

Many proteins share analogous structural elements that arose independently across different genomes. There are several examples of convergent protein motifs sharing similar arrangements of structural elements. Whole protein structures too have arisen through convergent evolution.

Protease active sites

The enzymology of proteases provides some of the clearest examples of convergent evolution. These examples reflect the intrinsic chemical constraints on enzymes, leading evolution to converge on equivalent solutions independently and repeatedly.

Serine and cysteine proteases use different amino acid functional groups (alcohol or thiol) as a nucleophile. To activate that nucleophile, they orient an acidic and a basic residue in a catalytic triad. The chemical and physical constraints on enzyme catalysis have caused identical triad arrangements to evolve independently more than 20 times in different enzyme superfamilies.

Threonine proteases use the amino acid threonine as their catalytic nucleophile. Unlike cysteine and serine, threonine is a secondary alcohol (i.e. has a methyl group). The methyl group of threonine greatly restricts the possible orientations of triad and substrate, as the methyl clashes with either the enzyme backbone or the histidine base. Consequently, most threonine proteases use an N-terminal threonine in order to avoid such steric clashes. Several evolutionarily independent enzyme superfamilies with different protein folds use the N-terminal residue as a nucleophile. This commonality of active site but difference of protein fold indicates that the active site evolved convergently in those families.

Cone snail and fish insulin

Conus geographus produces a distinct form of insulin that is more similar to fish insulin protein sequences than to insulin from more closely related molluscs, suggesting convergent evolution, though with the possibility of horizontal gene transfer.

Ferrous iron uptake via protein transporters in land plants and chlorophytes

Distant homologues of the metal ion transporters ZIP in land plants and chlorophytes have converged in structure, likely to take up Fe2+ efficiently. The IRT1 proteins from Arabidopsis thaliana and rice have extremely different amino acid sequences from Chlamydomonas's IRT1, but their three-dimensional structures are similar, suggesting convergent evolution.

Na+,K+-ATPase and Insect resistance to cardiotonic steroids

Many examples of convergent evolution exist in insects in terms of developing resistance at a molecular level to toxins. One well-characterized example is the evolution of resistance to cardiotonic steroids (CTSs) via amino acid substitutions at well-defined positions of the α-subunit of Na+,K+-ATPase (ATPalpha). Variation in ATPalpha has been surveyed in various CTS-adapted species spanning six insect orders. Among 21 CTS-adapted species, 58 (76%) of 76 amino acid substitutions at sites implicated in CTS resistance occur in parallel in at least two lineages. 30 of these substitutions (40%) occur at just two sites in the protein (positions 111 and 122). CTS-adapted species have also recurrently evolved neo-functionalized duplications of ATPalpha, with convergent tissue-specific expression patterns.

Nucleic acids

Convergence occurs at the level of DNA and the amino acid sequences produced by translating structural genes into proteins. Studies have found convergence in amino acid sequences in echolocating bats and the dolphin; among marine mammals; between giant and red pandas; and between the thylacine and canids. Convergence has also been detected in a type of non-coding DNA, cis-regulatory elements, such as in their rates of evolution; this could indicate either positive selection or relaxed purifying selection.

In animals

Dolphins and ichthyosaurs converged on many adaptations for fast swimming.

Bodyplans

Swimming animals including fish such as herrings, marine mammals such as dolphins, and ichthyosaurs (of the Mesozoic) all converged on the same streamlined shape. A similar shape and swimming adaptations are even present in molluscs, such as Phylliroe. The fusiform bodyshape (a tube tapered at both ends) adopted by many aquatic animals is an adaptation to enable them to travel at high speed in a high drag environment. Similar body shapes are found in the earless seals and the eared seals: they still have four legs, but these are strongly modified for swimming.

The marsupial fauna of Australia and the placental mammals of the Old World have several strikingly similar forms, developed in two clades, isolated from each other. The body, and especially the skull shape, of the thylacine (Tasmanian tiger or Tasmanian wolf) converged with those of Canidae such as the red fox, Vulpes vulpes.

Echolocation

As a sensory adaptation, echolocation has evolved separately in cetaceans (dolphins and whales) and bats, but from the same genetic mutations.

Electric fishes

The Gymnotiformes of South America and the Mormyridae of Africa independently evolved passive electroreception (around 119 and 110 million years ago, respectively). Around 20 million years after acquiring that ability, both groups evolved active electrogenesis, producing weak electric fields to help them detect prey.

Eyes

The camera eyes of vertebrates (left) and cephalopods (right) developed independently and are wired differently; for instance, optic nerve (3) fibres (2) reach the vertebrate retina (1) from the front, creating a blind spot (4).

One of the best-known examples of convergent evolution is the camera eye of cephalopods (such as squid and octopus), vertebrates (including mammals) and cnidarians (such as jellyfish). Their last common ancestor had at most a simple photoreceptive spot, but a range of processes led to the progressive refinement of camera eyes—with one sharp difference: the cephalopod eye is "wired" in the opposite direction, with blood and nerve vessels entering from the back of the retina, rather than the front as in vertebrates. As a result, vertebrates have a blind spot.

Sex organs

Hydrostatic penises have convergently evolved at least six times in male amniotes. In these species, males copulate with females and internally fertilize their eggs. Similar intromittent organs have evolved in invertebrates such as octopuses and gastropods.

Flight

Vertebrate wings are partly homologous (from forelimbs), but analogous as organs of flight in (1) pterosaurs, (2) bats, (3) birds, evolved separately.

Birds and bats have homologous limbs because they are both ultimately derived from terrestrial tetrapods, but their flight mechanisms are only analogous, so their wings are examples of functional convergence. The two groups have independently evolved their own means of powered flight. Their wings differ substantially in construction. The bat wing is a membrane stretched across four extremely elongated fingers and the legs. The airfoil of the bird wing is made of feathers, strongly attached to the forearm (the ulna) and the highly fused bones of the wrist and hand (the carpometacarpus), with only tiny remnants of two fingers remaining, each anchoring a single feather. So, while the wings of bats and birds are functionally convergent, they are not anatomically convergent. Birds and bats also share a high concentration of cerebrosides in the skin of their wings. This improves skin flexibility, a trait useful for flying animals; other mammals have a far lower concentration. The extinct pterosaurs independently evolved wings from their fore- and hindlimbs, while insects have wings that evolved separately from different organs.

Flying squirrels and sugar gliders are much alike in their mammalian body plans, with gliding wings stretched between their limbs, but flying squirrels are placentals while sugar gliders are marsupials, widely separated within the mammal lineage from the placentals.

Hummingbird hawk-moths and hummingbirds have evolved similar flight and feeding patterns.

Insect mouthparts

Insect mouthparts show many examples of convergent evolution. The mouthparts of different insect groups consist of a set of homologous organs, specialised for the dietary intake of that insect group. Convergent evolution of many groups of insects led from original biting-chewing mouthparts to different, more specialised, derived function types. These include, for example, the proboscis of flower-visiting insects such as bees and flower beetles, or the biting-sucking mouthparts of blood-sucking insects such as fleas and mosquitos.

Intelligence

Advanced intelligence has evolved independently in cephalopods and vertebrates. Octopus have demonstrated mammalian levels of problem-solving, cognition, and learning behaviors. One aquarium director even claimed his octopus specimen to have developed a sense of personal taste as to the arrangement of its tank. Unlike other highly intelligent animals, cephalopods typically live short lives with varying levels of sociality, with the bulk of the nervous system divided between the head and limbs.

Opposable thumbs

Opposable thumbs allowing the grasping of objects are most often associated with primates, like humans and other apes, monkeys, and lemurs. Opposable thumbs also evolved in giant pandas, but these are completely different in structure, having six fingers including the thumb, which develops from a wrist bone entirely separately from other fingers.

Primate phenotypes

Convergent evolution in humans includes blue eye colour and light skin colour. When humans migrated out of Africa, they moved to more northern latitudes with less intense sunlight. It was beneficial to them to have reduced skin pigmentation. It appears certain that there was some lightening of skin colour before European and East Asian lineages diverged, as there are some skin-lightening genetic differences that are common to both groups. However, after the lineages diverged and became genetically isolated, the skin of both groups lightened more, and that additional lightening was due to different genetic changes.


A_blue_eye.jpg



Despite the similarity of appearance, the genetic basis of blue eyes is different in humans and lemurs.

Lemurs and humans are both primates. Ancestral primates had brown eyes, as most primates do today. The genetic basis of blue eyes in humans has been studied in detail and much is known about it. It is not the case that one gene locus is responsible, say with brown dominant to blue eye colour. However, a single locus is responsible for about 80% of the variation. In lemurs, the differences between blue and brown eyes are not completely known, but the same gene locus is not involved.

In plants

In myrmecochory, seeds such as those of Chelidonium majus have a hard coating and an attached oil body, an elaiosome, for dispersal by ants.

The annual life-cycle

While most plant species are perennial, about 6% follow an annual life cycle, living for only one growing season. The annual life cycle independently emerged in over 120 plant families of angiosperms. The prevalence of annual species increases under hot-dry summer conditions in the four species-rich families of annuals (Asteraceae, Brassicaceae, Fabaceae, and Poaceae), indicating that the annual life cycle is adaptive.

Carbon fixation

C4 photosynthesis, one of the three major carbon-fixing biochemical processes, has arisen independently up to 40 times. About 7,600 plant species of angiosperms use C4 carbon fixation, with many monocots including 46% of grasses such as maize and sugar cane, and dicots including several species in the Chenopodiaceae and the Amaranthaceae.

Fruits

Fruits with a wide variety of structural origins have converged to become edible. Apples are pomes with five carpels; their accessory tissues form the apple's core, surrounded by structures from outside the botanical fruit, the receptacle or hypanthium. Other edible fruits include other plant tissues; the fleshy part of a tomato is the walls of the pericarp. This implies convergent evolution under selective pressure, in this case the competition for seed dispersal by animals through consumption of fleshy fruits.

Seed dispersal by ants (myrmecochory) has evolved independently more than 100 times, and is present in more than 11,000 plant species. It is one of the most dramatic examples of convergent evolution in biology.

Carnivory

Molecular convergence in carnivorous plants

Carnivory has evolved multiple times independently in plants in widely separated groups. In three species studied, Cephalotus follicularis, Nepenthes alata and Sarracenia purpurea, there has been convergence at the molecular level. Carnivorous plants secrete enzymes into the digestive fluid they produce. By studying phosphatase, glycoside hydrolase, glucanase, RNAse and chitinase enzymes as well as a pathogenesis-related protein and a thaumatin-related protein, the authors found many convergent amino acid substitutions. These changes were not at the enzymes' catalytic sites, but rather on the exposed surfaces of the proteins, where they might interact with other components of the cell or the digestive fluid. The authors also found that homologous genes in the non-carnivorous plant Arabidopsis thaliana tend to have their expression increased when the plant is stressed, leading the authors to suggest that stress-responsive proteins have often been co-opted in the repeated evolution of carnivory.

Methods of inference

Angiosperm phylogeny of orders based on classification by the Angiosperm Phylogeny Group. The figure shows the number of inferred independent origins of C3-C4 photosynthesis and C4 photosynthesis in parentheses.

Phylogenetic reconstruction and ancestral state reconstruction proceed by assuming that evolution has occurred without convergence. Convergent patterns may, however, appear at higher levels in a phylogenetic reconstruction, and are sometimes explicitly sought by investigators. The methods applied to infer convergent evolution depend on whether pattern-based or process-based convergence is expected. Pattern-based convergence is the broader term, for when two or more lineages independently evolve patterns of similar traits. Process-based convergence is when the convergence is due to similar forces of natural selection.

Pattern-based measures

Earlier methods for measuring convergence incorporate ratios of phenotypic and phylogenetic distance by simulating evolution with a Brownian motion model of trait evolution along a phylogeny. More recent methods also quantify the strength of convergence. One drawback to keep in mind is that these methods can confuse long-term stasis with convergence due to phenotypic similarities. Stasis occurs when there is little evolutionary change among taxa.

Distance-based measures assess the degree of similarity between lineages over time. Frequency-based measures assess the number of lineages that have evolved in a particular trait space.

Process-based measures

Methods to infer process-based convergence fit models of selection to a phylogeny and continuous trait data to determine whether the same selective forces have acted upon lineages. This uses the Ornstein–Uhlenbeck process to test different scenarios of selection. Other methods rely on an a priori specification of where shifts in selection have occurred.

Thursday, October 30, 2025

Distributed artificial intelligence

Distributed artificial intelligence (DAI) also called Decentralized Artificial Intelligence is a subfield of artificial intelligence research dedicated to the development of distributed solutions for problems. DAI is closely related to and a predecessor of the field of multi-agent systems.

Multi-agent systems and distributed problem solving are the two main DAI approaches. There are numerous applications and tools.

Definition

Distributed Artificial Intelligence (DAI) is an approach to solving complex learning, planning, and decision-making problems. It is embarrassingly parallel, thus able to exploit large scale computation and spatial distribution of computing resources. These properties allow it to solve problems that require the processing of very large data sets. DAI systems consist of autonomous learning processing nodes (agents), that are distributed, often at a very large scale. DAI nodes can act independently, and partial solutions are integrated by communication between nodes, often asynchronously. By virtue of their scale, DAI systems are robust and elastic, and by necessity, loosely coupled. Furthermore, DAI systems are built to be adaptive to changes in the problem definition or underlying data sets due to the scale and difficulty in redeployment.

DAI systems do not require all the relevant data to be aggregated in a single location, in contrast to monolithic or centralized Artificial Intelligence systems which have tightly coupled and geographically close processing nodes. Therefore, DAI systems often operate on sub-samples or hashed impressions of very large datasets. In addition, the source dataset may change or be updated during the course of the execution of a DAI system.

Development

In 1975 distributed artificial intelligence emerged as a subfield of artificial intelligence that dealt with interactions of intelligent agents. Distributed artificial intelligence systems were conceived as a group of intelligent entities, called agents, that interacted by cooperation, by coexistence or by competition. DAI is categorized into multi-agent systems and distributed problem solving. In multi-agent systems the main focus is how agents coordinate their knowledge and activities. For distributed problem solving the major focus is how the problem is decomposed and the solutions are synthesized.

Goals

The objectives of Distributed Artificial Intelligence are to solve the reasoning, planning, learning and perception problems of artificial intelligence, especially if they require large data, by distributing the problem to autonomous processing nodes (agents). To reach the objective, DAI requires:

  • A distributed system with robust and elastic computation on unreliable and failing resources that are loosely coupled
  • Coordination of the actions and communication of the nodes
  • Subsamples of large data sets and online machine learning

There are many reasons for wanting to distribute intelligence or cope with multi-agent systems. Mainstream problems in DAI research include the following:

  • Parallel problem solving: mainly deals with how classic artificial intelligence concepts can be modified, so that multiprocessor systems and clusters of computers can be used to speed up calculation.
  • Distributed problem solving (DPS): the concept of agent, autonomous entities that can communicate with each other, was developed to serve as an abstraction for developing DPS systems. See below for further details.
  • Multi-Agent Based Simulation (MABS): a branch of DAI that builds the foundation for simulations that need to analyze not only phenomena at macro level but also at micro level, as it is in many social simulation scenarios.

Approaches

Two types of DAI has emerged:

  • In Multi-agent systems agents coordinate their knowledge and activities and reason about the processes of coordination. Agents are physical or virtual entities that can act, perceive its environment and communicate with other agents. The agent is autonomous and has skills to achieve goals. The agents change the state of their environment by their actions. There are a number of different coordination techniques.
  • In distributed problem solving the work is divided among nodes and the knowledge is shared. The main concerns are task decomposition and synthesis of the knowledge and solutions.

DAI can apply a bottom-up approach to AI, similar to the subsumption architecture as well as the traditional top-down approach of AI. In addition, DAI can also be a vehicle for emergence.

Challenges

The challenges in Distributed AI are:

  1. How to carry out communication and interaction of agents and which communication language or protocols should be used.
  2. How to ensure the coherency of agents.
  3. How to synthesise the results among 'intelligent agents' group by formulation, description, decomposition and allocation.

Applications and tools

Areas where DAI have been applied are:

DAI integration in tools has included:

  • ECStar is a distributed rule-based learning system.

Agents

Systems: Agents and multi-agents

Notion of Agents: Agents can be described as distinct entities with standard boundaries and interfaces designed for problem solving.

Notion of Multi-Agents: Multi-Agent system is defined as a network of agents which are loosely coupled working as a single entity like society for problem solving that an individual agent cannot solve.

Software agents

The key concept used in DPS and MABS is the abstraction called software agents. An agent is a virtual (or physical) autonomous entity that has an understanding of its environment and acts upon it. An agent is usually able to communicate with other agents in the same system to achieve a common goal, that one agent alone could not achieve. This communication system uses an agent communication language.

A first classification that is useful is to divide agents into:

  • reactive agent – A reactive agent is not much more than an automaton that receives input, processes it and produces an output.
  • deliberative agent – A deliberative agent in contrast should have an internal view of its environment and is able to follow its own plans.
  • hybrid agent – A hybrid agent is a mixture of reactive and deliberative, that follows its own plans, but also sometimes directly reacts to external events without deliberation.

Well-recognized agent architectures that describe how an agent is internally structured are:

  • ASMO (emergence of distributed modules)
  • BDI (Believe Desire Intention, a general architecture that describes how plans are made)
  • InterRAP (A three-layer architecture, with a reactive, a deliberative and a social layer)
  • PECS (Physics, Emotion, Cognition, Social, describes how those four parts influences the agents behavior).
  • Soar (a rule-based approach)

Molecular machine

From Wikipedia, the free encyclopedia https://en.wikipedia.org/wiki/Mol...