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Sunday, September 10, 2023

Plague (disease)

From Wikipedia, the free encyclopedia
Plague
Yersinia pestis seen at 200× magnification with a fluorescent label.
SpecialtyInfectious disease
SymptomsFever, weakness, headache
Usual onset1–7 days after exposure
TypesBubonic plague, septicemic plague, pneumonic plague
CausesYersinia pestis
Diagnostic methodFinding the bacterium in a lymph node, blood, sputum
PreventionPlague vaccine
TreatmentAntibiotics and supportive care
MedicationGentamicin and a fluoroquinolone
Prognosis≈10% risk of death (with treatment)
Frequency≈600 cases a year

Plague is an infectious disease caused by the bacterium Yersinia pestis. Symptoms include fever, weakness and headache. Usually this begins one to seven days after exposure. There are three forms of plague, each affecting a different part of the body and causing associated symptoms. Pneumonic plague infects the lungs, causing shortness of breath, coughing and chest pain; bubonic plague affects the lymph nodes, making them swell; and septicemic plague infects the blood and can cause tissues to turn black and die.

The bubonic and septicemic forms are generally spread by flea bites or handling an infected animal, whereas pneumonic plague is generally spread between people through the air via infectious droplets. Diagnosis is typically by finding the bacterium in fluid from a lymph node, blood or sputum.

Those at high risk may be vaccinated. Those exposed to a case of pneumonic plague may be treated with preventive medication. If infected, treatment is with antibiotics and supportive care. Typically antibiotics include a combination of gentamicin and a fluoroquinolone. The risk of death with treatment is about 10% while without it is about 70%.

Globally, about 600 cases are reported a year. In 2017, the countries with the most cases include the Democratic Republic of the Congo, Madagascar and Peru. In the United States, infections occasionally occur in rural areas, where the bacteria are believed to circulate among rodents. It has historically occurred in large outbreaks, with the best known being the Black Death in the 14th century, which resulted in more than 50 million deaths in Europe.

Signs and symptoms

There are several different clinical manifestations of plague. The most common form is bubonic plague, followed by septicemic and pneumonic plague. Other clinical manifestations include plague meningitis, plague pharyngitis, and ocular plague. General symptoms of plague include fever, chills, headaches, and nausea. Many people experience swelling in their lymph nodes if they have bubonic plague. For those with pneumonic plague, symptoms may (or may not) include a cough, pain in the chest, and haemoptysis.

Bubonic plague

Swollen inguinal lymph glands on a person infected with the bubonic plague. The swollen lymph glands are termed buboes from the Greek word for groin, swollen gland: bubo.

When a flea bites a human and contaminates the wound with regurgitated blood, the plague-causing bacteria are passed into the tissue. Y. pestis can reproduce inside cells, so even if phagocytosed, they can still survive. Once in the body, the bacteria can enter the lymphatic system, which drains interstitial fluid. Plague bacteria secrete several toxins, one of which is known to cause beta-adrenergic blockade.

Y. pestis spreads through the lymphatic vessels of the infected human until it reaches a lymph node, where it causes acute lymphadenitis. The swollen lymph nodes form the characteristic buboes associated with the disease, and autopsies of these buboes have revealed them to be mostly hemorrhagic or necrotic.

If the lymph node is overwhelmed, the infection can pass into the bloodstream, causing secondary septicemic plague and if the lungs are seeded, it can cause secondary pneumonic plague.

Septicemic plague

Septicemic plague resulting in necrosis

Lymphatics ultimately drain into the bloodstream, so the plague bacteria may enter the blood and travel to almost any part of the body. In septicemic plague, bacterial endotoxins cause disseminated intravascular coagulation (DIC), causing tiny clots throughout the body and possibly ischemic necrosis (tissue death due to lack of circulation/perfusion to that tissue) from the clots. DIC results in depletion of the body's clotting resources so that it can no longer control bleeding. Consequently, there is bleeding into the skin and other organs, which can cause red and/or black patchy rash and hemoptysis/hematemesis (coughing up/ vomiting of blood). There are bumps on the skin that look somewhat like insect bites; these are usually red, and sometimes white in the centre. Untreated, the septicemic plague is usually fatal. Early treatment with antibiotics reduces the mortality rate to between 4 and 15 per cent.

Pneumonic plague

The pneumonic form of plague arises from infection of the lungs. It causes coughing and thereby produces airborne droplets that contain bacterial cells and are likely to infect anyone inhaling them. The incubation period for pneumonic plague is short, usually two to four days, but sometimes just a few hours. The initial signs are indistinguishable from several other respiratory illnesses; they include headache, weakness, and spitting or vomiting of blood. The course of the disease is rapid; unless diagnosed and treated soon enough, typically within a few hours, death may follow in one to six days; in untreated cases, mortality is nearly 100%.

Cause

The Oriental rat flea (Xenopsylla cheopis) engorged with blood after a blood meal. This species of flea is the primary vector for the transmission of Yersinia pestis, the organism responsible for bubonic plague in most plague epidemics in Asia, Africa, and South America. Both male and female fleas feed on blood and can transmit the infection.
A child bitten by a flea infected with the bacterium Yersinia pestis. Y. pestis, a member of the family Yersiniaceae, has caused the bite to become ulcerated.

Transmission of Y. pestis to an uninfected individual is possible by any of the following means:

  • droplet contact – coughing or sneezing on another person
  • Direct physical contact;– touching an infected person, including sexual contact
  • indirect contact – usually by touching soil contamination or a contaminated surface
  • airborne transmission – if the microorganism can remain in the air for long periods
  • fecal-oral transmission – usually from contaminated food or water sources
  • vector borne transmission – carried by insects or other animals.

Yersinia pestis circulates in animal reservoirs, particularly in rodents, in the natural foci of infection found on all continents except Australia. The natural foci of plague are situated in a broad belt in the tropical and sub-tropical latitudes and the warmer parts of the temperate latitudes around the globe, between the parallels 55° N and 40° S. Contrary to popular belief, rats did not directly start the spread of the bubonic plague. It is mainly a disease in the fleas (Xenopsylla cheopis) that infested the rats, making the rats themselves the first victims of the plague. Rodent-borne infection in a human occurs when a person is bitten by a flea that has been infected by biting a rodent that itself has been infected by the bite of a flea carrying the disease. The bacteria multiply inside the flea, sticking together to form a plug that blocks its stomach and causes it to starve. The flea then bites a host and continues to feed, even though it cannot quell its hunger, and consequently, the flea vomits blood tainted with the bacteria back into the bite wound. The bubonic plague bacterium then infects a new person and the flea eventually dies from starvation. Serious outbreaks of plague are usually started by other disease outbreaks in rodents or a rise in the rodent population.

A 21st-century study of a 1665 outbreak of plague in the village of Eyam in England's Derbyshire Dales – which isolated itself during the outbreak, facilitating modern study – found that three-quarters of cases are likely to have been due to human-to-human transmission, especially within families, a much bigger proportion than previously thought.

Diagnosis

Symptoms of plague are usually non-specific and to definitively diagnose plague, laboratory testing is required. Y. pestis can be identified through both a microscope and by culturing a sample and this is used as a reference standard to confirm that a person has a case of plague. The sample can be obtained from the blood, mucus (sputum), or aspirate extracted from inflamed lymph nodes (buboes). If a person is administered antibiotics before a sample is taken or if there is a delay in transporting the person's sample to a laboratory and/or a poorly stored sample, there is a possibility for false negative results.

Polymerase chain reaction (PCR) may also be used to diagnose plague, by detecting the presence of bacterial genes such as the pla gene (plasmogen activator) and caf1 gene, (F1 capsule antigen). PCR testing requires a very small sample and is effective for both alive and dead bacteria. For this reason, if a person receives antibiotics before a sample is collected for laboratory testing, they may have a false negative culture and a positive PCR result.

Blood tests to detect antibodies against Y. pestis can also be used to diagnose plague, however, this requires taking blood samples at different periods to detect differences between the acute and convalescent phases of F1 antibody titres.

In 2020, a study about rapid diagnostic tests that detect the F1 capsule antigen (F1RDT) by sampling sputum or bubo aspirate was released. Results show rapid diagnostic F1RDT test can be used for people who have suspected pneumonic and bubonic plague but cannot be used in asymptomatic people. F1RDT may be useful in providing a fast result for prompt treatment and fast public health response as studies suggest that F1RDT is highly sensitive for both pneumonic and bubonic plague. However, when using the rapid test, both positive and negative results need to be confirmed to establish or reject the diagnosis of a confirmed case of plague and the test result needs to be interpreted within the epidemiological context as study findings indicate that although 40 out of 40 people who had the plague in a population of 1000 were correctly diagnosed, 317 people were diagnosed falsely as positive.

Prevention

Vaccination

Bacteriologist Waldemar Haffkine developed the first plague vaccine in 1897. He conducted a massive inoculation program in British India, and it is estimated that 26 million doses of Haffkine's anti-plague vaccine were sent out from Bombay between 1897 and 1925, reducing the plague mortality by 50–85%.

Since human plague is rare in most parts of the world as of 2023, routine vaccination is not needed other than for those at particularly high risk of exposure, nor for people living in areas with enzootic plague, meaning it occurs at regular, predictable rates in populations and specific areas, such as the western United States. It is not even indicated for most travellers to countries with known recent reported cases, particularly if their travel is limited to urban areas with modern hotels. The United States CDC thus only recommends vaccination for (1) all laboratory and field personnel who are working with Y. pestis organisms resistant to antimicrobials: (2) people engaged in aerosol experiments with Y. pestis; and (3) people engaged in field operations in areas with enzootic plague where preventing exposure is not possible (such as some disaster areas). A systematic review by the Cochrane Collaboration found no studies of sufficient quality to make any statement on the efficacy of the vaccine.

Early diagnosis

Diagnosing plague early leads to a decrease in transmission or spread of the disease.

Prophylaxis

Pre-exposure prophylaxis for first responders and health care providers who will care for patients with pneumonic plague is not considered necessary as long as standard and droplet precautions can be maintained. In cases of surgical mask shortages, patient overcrowding, poor ventilation in hospital wards, or other crises, pre-exposure prophylaxis might be warranted if sufficient supplies of antimicrobials are available.

Postexposure prophylaxis should be considered for people who had close (<6 feet), sustained contact with a patient with pneumonic plague and were not wearing adequate personal protective equipment. Antimicrobial postexposure prophylaxis also can be considered for laboratory workers accidentally exposed to infectious materials and people who had close (<6 feet) or direct contact with infected animals, such as veterinary staff, pet owners, and hunters.

Specific recommendations on pre- and post-exposure prophylaxis are available in the clinical guidelines on treatment and prophylaxis of plague published in 2021.

Treatments

If diagnosed in time, the various forms of plague are usually highly responsive to antibiotic therapy. The antibiotics often used are streptomycin, chloramphenicol and tetracycline. Amongst the newer generation of antibiotics, gentamicin and doxycycline have proven effective in monotherapeutic treatment of plague. Guidelines on treatment and prophylaxis of plague were published by the Centers for Disease Control and Prevention in 2021.

The plague bacterium could develop drug resistance and again become a major health threat. One case of a drug-resistant form of the bacterium was found in Madagascar in 1995. Further outbreaks in Madagascar were reported in November 2014 and October 2017.

Epidemiology

Distribution of plague-infected animals 1998

Globally about 600 cases are reported a year. In 2017, the countries with the most cases include the Democratic Republic of the Congo, Madagascar and Peru. It has historically occurred in large outbreaks, with the best known being the Black Death in the 14th century which resulted in more than 50 million dead. In recent years, cases have been distributed between small seasonal outbreaks which occur primarily in Madagascar, and sporadic outbreaks or isolated cases in endemic areas.

In 2022 the possible origin of all modern strands of Yersinia pestis DNA was found in human remains in three graves located in Kyrgyzstan, dated to 1338 and 1339. The siege of Caffa in Crimea in 1346, is known to have been the first plague outbreak with following strands, later to spread over Europe. Sequencing DNA compared to other ancient and modern strands paints a family tree of the bacteria. Bacteria today affecting marmots in Kyrgyzstan, are closest to the strand found in the graves, suggesting this is also the location where plague transferred from animals to humans.

Biological weapon

The plague has a long history as a biological weapon. Historical accounts from ancient China and medieval Europe details the use of infected animal carcasses, such as cows or horses, and human carcasses, by the Xiongnu/Huns, Mongols, Turks and other groups, to contaminate enemy water supplies. Han Dynasty General Huo Qubing is recorded to have died of such contamination while engaging in warfare against the Xiongnu. Plague victims were also reported to have been tossed by catapult into cities under siege.

In 1347, the Genoese possession of Caffa, a great trade emporium on the Crimean peninsula, came under siege by an army of Mongol warriors of the Golden Horde under the command of Jani Beg. After a protracted siege during which the Mongol army was reportedly withering from the disease, they decided to use the infected corpses as a biological weapon. The corpses were catapulted over the city walls, infecting the inhabitants. This event might have led to the transfer of the Black Death via their ships into the south of Europe, possibly explaining its rapid spread.

During World War II, the Japanese Army developed weaponized plague, based on the breeding and release of large numbers of fleas. During the Japanese occupation of Manchuria, Unit 731 deliberately infected Chinese, Korean and Manchurian civilians and prisoners of war with the plague bacterium. These subjects, termed "maruta" or "logs", were then studied by dissection, others by vivisection while still conscious. Members of the unit such as Shiro Ishii were exonerated from the Tokyo tribunal by Douglas MacArthur but 12 of them were prosecuted in the Khabarovsk War Crime Trials in 1949 during which some admitted having spread bubonic plague within a 36-kilometre (22 mi) radius around the city of Changde.

Ishii innovated bombs containing live mice and fleas, with very small explosive loads, to deliver the weaponized microbes, overcoming the problem of the explosive killing the infected animal and insect by the use of a ceramic, rather than metal, casing for the warhead. While no records survive of the actual usage of the ceramic shells, prototypes exist and are believed to have been used in experiments during WWII.

After World War II, both the United States and the Soviet Union developed means of weaponising pneumonic plague. Experiments included various delivery methods, vacuum drying, sizing the bacterium, developing strains resistant to antibiotics, combining the bacterium with other diseases (such as diphtheria), and genetic engineering. Scientists who worked in USSR bio-weapons programs have stated that the Soviet effort was formidable and that large stocks of weaponised plague bacteria were produced. Information on many of the Soviet and US projects is largely unavailable. Aerosolized pneumonic plague remains the most significant threat.

The plague can be easily treated with antibiotics. Some countries, such as the United States, have large supplies on hand if such an attack should occur, making the threat less severe.

Theory of categories

From Wikipedia, the free encyclopedia

In ontology, the theory of categories concerns itself with the categories of being: the highest genera or kinds of entities according to Amie Thomasson. To investigate the categories of being, or simply categories, is to determine the most fundamental and the broadest classes of entities. A distinction between such categories, in making the categories or applying them, is called an ontological distinction. Various systems of categories have been proposed, they often include categories for substances, properties, relations, states of affairs or events. A representative question within the theory of categories might articulate itself, for example, in a query like, "Are universals prior to particulars?"

Early development

The process of abstraction required to discover the number and names of the categories of being has been undertaken by many philosophers since Aristotle and involves the careful inspection of each concept to ensure that there is no higher category or categories under which that concept could be subsumed. The scholars of the twelfth and thirteenth centuries developed Aristotle's ideas. For example, Gilbert of Poitiers divides Aristotle's ten categories into two sets, primary and secondary, according to whether they inhere in the subject or not:

  • Primary categories: Substance, Relation, Quantity and Quality
  • Secondary categories: Place, Time, Situation, Condition, Action, Passion

Furthermore, following Porphyry’s likening of the classificatory hierarchy to a tree, they concluded that the major classes could be subdivided to form subclasses, for example, Substance could be divided into Genus and Species, and Quality could be subdivided into Property and Accident, depending on whether the property was necessary or contingent. An alternative line of development was taken by Plotinus in the second century who by a process of abstraction reduced Aristotle's list of ten categories to five: Substance, Relation, Quantity, Motion and Quality. Plotinus further suggested that the latter three categories of his list, namely Quantity, Motion and Quality correspond to three different kinds of relation and that these three categories could therefore be subsumed under the category of Relation. This was to lead to the supposition that there were only two categories at the top of the hierarchical tree, namely Substance and Relation. Many supposed that relations only exist in the mind. Substance and Relation, then, are closely commutative with Mind and Matter--this is expressed most clearly in the dualism of René Descartes.

Vaisheshika

Padārtha is a Sanskrit word for "categories" in Vaisheshika and Nyaya schools of Indian philosophy.

Stoic

The Stoics held that all beings (ὄντα)—though not all things (τινά)—are material. Besides the existing beings they admitted four incorporeals (asomata): time, place, void, and sayable. They were held to be just 'subsisting' while such a status was denied to universals. Thus, they accepted Anaxagoras's idea (as did Aristotle) that if an object is hot, it is because some part of a universal heat body had entered the object. But, unlike Aristotle, they extended the idea to cover all accidents. Thus, if an object is red, it would be because some part of a universal red body had entered the object.

They held that there were four categories.

  1. Substance (ὑποκείμενον): The primary matter, formless substance, (ousia) that things are made of
  2. Quality (ποιόν): The way matter is organized to form an individual object; in Stoic physics, a physical ingredient (pneuma: air or breath), which informs the matter
  3. Somehow disposed (πως ἔχον): Particular characteristics, not present within the object, such as size, shape, action, and posture
  4. Somehow disposed in relation to something (πρός τί πως ἔχον): Characteristics related to other phenomena, such as the position of an object within time and space relative to other objects

The Stoics outlined that our own actions, thoughts, and reactions are within our control. The opening paragraph of the Enchiridion states the categories as: "Some things in the world are up to us, while others are not. Up to us are our faculties of judgment, motivation, desire, and aversion. In short, whatever is our own doing." These suggest a space that is up to us or within our power. A simple example of the Stoic categories in use is provided by Jacques Brunschwig:

I am a certain lump of matter, and thereby a substance, an existent something (and thus far that is all); I am a man, and this individual man that I am, and thereby qualified by a common quality and a peculiar one; I am sitting or standing, disposed in a certain way; I am the father of my children, the fellow citizen of my fellow citizens, disposed in a certain way in relation to something else.

Aristotle

One of Aristotle’s early interests lay in the classification of the natural world, how for example the genus "animal" could be first divided into "two-footed animal" and then into "wingless, two-footed animal". He realised that the distinctions were being made according to the qualities the animal possesses, the quantity of its parts and the kind of motion that it exhibits. To fully complete the proposition "this animal is ..." Aristotle stated in his work on the Categories that there were ten kinds of predicate where ...

"... each signifies either substance or quantity or quality or relation or where or when or being-in-a-position or having or acting or being acted upon".

He realised that predicates could be simple or complex. The simple kinds consist of a subject and a predicate linked together by the "categorical" or inherent type of relation. For Aristotle the more complex kinds were limited to propositions where the predicate is compounded of two of the above categories for example "this is a horse running". More complex kinds of proposition were only discovered after Aristotle by the Stoic, Chrysippus, who developed the "hypothetical" and "disjunctive" types of syllogism and these were terms which were to be developed through the Middle Ages and were to reappear in Kant's system of categories.

Category came into use with Aristotle's essay Categories, in which he discussed univocal and equivocal terms, predication, and ten categories:

  • Substance, essence (ousia) – examples of primary substance: this man, this horse; secondary substance (species, genera): man, horse
  • Quantity (poson, how much), discrete or continuous – examples: two cubits long, number, space, (length of) time.
  • Quality (poion, of what kind or description) – examples: white, black, grammatical, hot, sweet, curved, straight.
  • Relation (pros ti, toward something) – examples: double, half, large, master, knowledge.
  • Place (pou, where) – examples: in a marketplace, in the Lyceum
  • Time (pote, when) – examples: yesterday, last year
  • Position, posture, attitude (keisthai, to lie) – examples: sitting, lying, standing
  • State, condition (echein, to have or be) – examples: shod, armed
  • Action (poiein, to make or do) – examples: to lance, to heat, to cool (something)
  • Affection, passion (paschein, to suffer or undergo) – examples: to be lanced, to be heated, to be cooled

Plotinus

Plotinus in writing his Enneads around AD 250 recorded that "philosophy at a very early age investigated the number and character of the existents ... some found ten, others less .... to some the genera were the first principles, to others only a generic classification of existents". He realised that some categories were reducible to others saying "why are not Beauty, Goodness and the virtues, Knowledge and Intelligence included among the primary genera?" He concluded that such transcendental categories and even the categories of Aristotle were in some way posterior to the three Eleatic categories first recorded in Plato's dialogue Parmenides and which comprised the following three coupled terms:

  • Unity/Plurality
  • Motion/Stability
  • Identity/Difference

Plotinus called these "the hearth of reality" deriving from them not only the three categories of Quantity, Motion and Quality but also what came to be known as "the three moments of the Neoplatonic world process":

  • First, there existed the "One", and his view that "the origin of things is a contemplation"
  • The Second "is certainly an activity ... a secondary phase ... life streaming from life ... energy running through the universe"
  • The Third is some kind of Intelligence concerning which he wrote "Activity is prior to Intellection ... and self knowledge"

Plotinus likened the three to the centre, the radii and the circumference of a circle, and clearly thought that the principles underlying the categories were the first principles of creation. "From a single root all being multiplies". Similar ideas were to be introduced into Early Christian thought by, for example, Gregory of Nazianzus who summed it up saying "Therefore, Unity, having from all eternity arrived by motion at duality, came to rest in trinity".

Modern development

Kant and Hegel accused the Aristotelian table of categories of being 'rhapsodic', derived arbitrarily and in bulk from experience, without any systematic necessity.

The early modern dualism, which has been described above, of Mind and Matter or Subject and Relation, as reflected in the writings of Descartes underwent a substantial revision in the late 18th century. The first objections to this stance were formulated in the eighteenth century by Immanuel Kant who realised that we can say nothing about Substance except through the relation of the subject to other things.

For example: In the sentence "This is a house" the substantive subject "house" only gains meaning in relation to human use patterns or to other similar houses. The category of Substance disappears from Kant's tables, and under the heading of Relation, Kant lists inter alia the three relationship types of Disjunction, Causality and Inherence. The three older concepts of Quantity, Motion and Quality, as Peirce discovered, could be subsumed under these three broader headings in that Quantity relates to the subject through the relation of Disjunction; Motion relates to the subject through the relation of Causality; and Quality relates to the subject through the relation of Inherence. Sets of three continued to play an important part in the nineteenth century development of the categories, most notably in G.W.F. Hegel's extensive tabulation of categories, and in C.S. Peirce's categories set out in his work on the logic of relations. One of Peirce's contributions was to call the three primary categories Firstness, Secondness and Thirdness which both emphasises their general nature, and avoids the confusion of having the same name for both the category itself and for a concept within that category.

In a separate development, and building on the notion of primary and secondary categories introduced by the Scholastics, Kant introduced the idea that secondary or "derivative" categories could be derived from the primary categories through the combination of one primary category with another. This would result in the formation of three secondary categories: the first, "Community" was an example that Kant gave of such a derivative category; the second, "Modality", introduced by Kant, was a term which Hegel, in developing Kant's dialectical method, showed could also be seen as a derivative category; and the third, "Spirit" or "Will" were terms that Hegel and Schopenhauer were developing separately for use in their own systems. Karl Jaspers in the twentieth century, in his development of existential categories, brought the three together, allowing for differences in terminology, as Substantiality, Communication and Will. This pattern of three primary and three secondary categories was used most notably in the nineteenth century by Peter Mark Roget to form the six headings of his Thesaurus of English Words and Phrases. The headings used were the three objective categories of Abstract Relation, Space (including Motion) and Matter and the three subjective categories of Intellect, Feeling and Volition, and he found that under these six headings all the words of the English language, and hence any possible predicate, could be assembled.

Kant

In the Critique of Pure Reason (1781), Immanuel Kant argued that the categories are part of our own mental structure and consist of a set of a priori concepts through which we interpret the world around us. These concepts correspond to twelve logical functions of the understanding which we use to make judgements and there are therefore two tables given in the Critique, one of the Judgements and a corresponding one for the Categories. To give an example, the logical function behind our reasoning from ground to consequence (based on the Hypothetical relation) underlies our understanding of the world in terms of cause and effect (the Causal relation). In each table the number twelve arises from, firstly, an initial division into two: the Mathematical and the Dynamical; a second division of each of these headings into a further two: Quantity and Quality, and Relation and Modality respectively; and, thirdly, each of these then divides into a further three subheadings as follows.

Table of Judgements

Mathematical

  • Quantity
    • Universal
    • Particular
    • Singular
  • Quality
    • Affirmative
    • Negative
    • Infinite

Dynamical

  • Relation
    • Categorical
    • Hypothetical
    • Disjunctive
  • Modality
    • Problematic
    • Assertoric
    • Apodictic

Table of Categories

Mathematical

Dynamical

Criticism of Kant's system followed, firstly, by Arthur Schopenhauer, who amongst other things was unhappy with the term "Community", and declared that the tables "do open violence to truth, treating it as nature was treated by old-fashioned gardeners", and secondly, by W.T.Stace who in his book The Philosophy of Hegel suggested that in order to make Kant's structure completely symmetrical a third category would need to be added to the Mathematical and the Dynamical. This, he said, Hegel was to do with his category of concept.

Hegel

G.W.F. Hegel in his Science of Logic (1812) attempted to provide a more comprehensive system of categories than Kant and developed a structure that was almost entirely triadic. So important were the categories to Hegel that he claimed the first principle of the world, which he called the "absolute", is "a system of categories ... the categories must be the reason of which the world is a consequent".

Using his own logical method of sublation, later called the Hegelian dialectic, reasoning from the abstract through the negative to the concrete, he arrived at a hierarchy of some 270 categories, as explained by W. T. Stace. The three very highest categories were "logic", "nature" and "spirit". The three highest categories of "logic", however, he called "being", "essence", and "notion" which he explained as follows:

  • Being was differentiated from Nothing by containing with it the concept of the "other", an initial internal division that can be compared with Kant's category of disjunction. Stace called the category of Being the sphere of common sense containing concepts such as consciousness, sensation, quantity, quality and measure.
  • Essence. The "other" separates itself from the "one" by a kind of motion, reflected in Hegel's first synthesis of "becoming". For Stace this category represented the sphere of science containing within it firstly, the thing, its form and properties; secondly, cause, effect and reciprocity, and thirdly, the principles of classification, identity and difference.
  • Notion. Having passed over into the "Other" there is an almost neoplatonic return into a higher unity that in embracing the "one" and the "other" enables them to be considered together through their inherent qualities. This according to Stace is the sphere of philosophy proper where we find not only the three types of logical proposition: disjunctive, hypothetical, and categorical but also the three transcendental concepts of beauty, goodness and truth.

Schopenhauer's category that corresponded with "notion" was that of "idea", which in his Four-Fold Root of Sufficient Reason he complemented with the category of the "will". The title of his major work was The World as Will and Idea. The two other complementary categories, reflecting one of Hegel's initial divisions, were those of Being and Becoming. At around the same time, Goethe was developing his colour theories in the Farbenlehre of 1810, and introduced similar principles of combination and complementation, symbolising, for Goethe, "the primordial relations which belong both to nature and vision". Hegel in his Science of Logic accordingly asks us to see his system not as a tree but as a circle.

Twentieth-century development

In the twentieth century the primacy of the division between the subjective and the objective, or between mind and matter, was disputed by, among others, Bertrand Russell and Gilbert Ryle. Philosophy began to move away from the metaphysics of categorisation towards the linguistic problem of trying to differentiate between, and define, the words being used. Ludwig Wittgenstein’s conclusion was that there were no clear definitions which we can give to words and categories but only a "halo" or "corona" of related meanings radiating around each term. Gilbert Ryle thought the problem could be seen in terms of dealing with "a galaxy of ideas" rather than a single idea, and suggested that category mistakes are made when a concept (e.g. "university"), understood as falling under one category (e.g. abstract idea), is used as though it falls under another (e.g. physical object). With regard to the visual analogies being used, Peirce and Lewis, just like Plotinus earlier, likened the terms of propositions to points, and the relations between the terms to lines. Peirce, taking this further, talked of univalent, bivalent and trivalent relations linking predicates to their subject and it is just the number and types of relation linking subject and predicate that determine the category into which a predicate might fall. Primary categories contain concepts where there is one dominant kind of relation to the subject. Secondary categories contain concepts where there are two dominant kinds of relation. Examples of the latter were given by Heidegger in his two propositions "the house is on the creek" where the two dominant relations are spatial location (Disjunction) and cultural association (Inherence), and "the house is eighteenth century" where the two relations are temporal location (Causality) and cultural quality (Inherence). A third example may be inferred from Kant in the proposition "the house is impressive or sublime" where the two relations are spatial or mathematical disposition (Disjunction) and dynamic or motive power (Causality). Both Peirce and Wittgenstein introduced the analogy of colour theory in order to illustrate the shades of meanings of words. Primary categories, like primary colours, are analytical representing the furthest we can go in terms of analysis and abstraction and include Quantity, Motion and Quality. Secondary categories, like secondary colours, are synthetic and include concepts such as Substance, Community and Spirit.

Apart from these, the categorial scheme of Alfred North Whitehead and his Process Philosophy, alongside Nicolai Hartmann and his Critical Realism, remain one of the most detailed and advanced systems in categorial research in metaphysics.

Peirce

Charles Sanders Peirce, who had read Kant and Hegel closely, and who also had some knowledge of Aristotle, proposed a system of merely three phenomenological categories: Firstness, Secondness, and Thirdness, which he repeatedly invoked in his subsequent writings. Like Hegel, C.S. Peirce attempted to develop a system of categories from a single indisputable principle, in Peirce's case the notion that in the first instance he could only be aware of his own ideas. "It seems that the true categories of consciousness are first, feeling ... second, a sense of resistance ... and third, synthetic consciousness, or thought". Elsewhere he called the three primary categories: Quality, Reaction and Meaning, and even Firstness, Secondness and Thirdness, saying, "perhaps it is not right to call these categories conceptions, they are so intangible that they are rather tones or tints upon conceptions":

  • Firstness (Quality): "The first is predominant in feeling ... we must think of a quality without parts, e.g. the colour of magenta ... When I say it is a quality I do not mean that it "inheres" in a subject ... The whole content of consciousness is made up of qualities of feeling, as truly as the whole of space is made up of points, or the whole of time by instants".
  • Secondness (Reaction): "This is present even in such a rudimentary fragment of experience as a simple feeling ... an action and reaction between our soul and the stimulus ... The idea of second is predominant in the ideas of causation and of statical force ... the real is active; we acknowledge it by calling it the actual".
  • Thirdness (Meaning): "Thirdness is essentially of a general nature ... ideas in which thirdness predominate [include] the idea of a sign or representation ... Every genuine triadic relation involves meaning ... the idea of meaning is irreducible to those of quality and reaction ... synthetical consciousness is the consciousness of a third or medium".

Although Peirce's three categories correspond to the three concepts of relation given in Kant's tables, the sequence is now reversed and follows that given by Hegel, and indeed before Hegel of the three moments of the world-process given by Plotinus. Later, Peirce gave a mathematical reason for there being three categories in that although monadic, dyadic and triadic nodes are irreducible, every node of a higher valency is reducible to a "compound of triadic relations". Ferdinand de Saussure, who was developing "semiology" in France just as Peirce was developing "semiotics" in the US, likened each term of a proposition to "the centre of a constellation, the point where other coordinate terms, the sum of which is indefinite, converge".

Others

Edmund Husserl (1962, 2000) wrote extensively about categorial systems as part of his phenomenology.

For Gilbert Ryle (1949), a category (in particular a "category mistake") is an important semantic concept, but one having only loose affinities to an ontological category.

Contemporary systems of categories have been proposed by John G. Bennett (The Dramatic Universe, 4 vols., 1956–65), Wilfrid Sellars (1974), Reinhardt Grossmann (1983, 1992), Johansson (1989), Hoffman and Rosenkrantz (1994), Roderick Chisholm (1996), Barry Smith (ontologist) (2003), and Jonathan Lowe (2006).

World domination

From Wikipedia, the free encyclopedia
https://en.wikipedia.org/wiki/World_domination

World domination (also called global domination or world conquest or cosmocracy) is a hypothetical power structure, either achieved or aspired to, in which a single political authority holds the power over all or virtually all the inhabitants of Earth. Various individuals or regimes have tried to achieve this goal throughout history, without ever attaining it. The theme has been often used in works of fiction, particularly in political fiction, as well as in conspiracy theories (which may posit that some person or group has already secretly achieved this goal), particularly those fearing the development of a "New World Order" involving a world government of a totalitarian nature.

History

The British Empire at its territorial peak in 1921

While various empires over the course of history have been able to expand and dominate large parts of the world, none have come close to conquering all the territory on Earth. However, these empires have had a global impact in cultural and economic terms that is still felt today. Some of the largest and more prominent empires include:

By the early 21st century, wars of territorial conquest were uncommon and the world's nations could attempt to resolve their differences through multilateral diplomacy under the auspices of global organizations like the United Nations and World Trade Organization. The world's superpowers and potential superpowers rarely attempt to exert global influence through the types of territorial empire-building seen in history, but the influence of historical empires is still important and the idea of world domination is still socially and culturally relevant.

Social and political ideologies

By 500 BC, Darius the Great had created the largest empire up until that time, but it was still only a fraction of the land and people of the Earth (controlling near half population of the entire world).

Historically, world domination has been thought of in terms of a nation expanding its power to the point that all other nations are subservient to it. This may be achieved by establishing a hegemony, an indirect form of government and of imperial dominance in which the hegemon (leading state) controls geopolitically subordinate states by means of its implied power—by the threat of force, rather than by direct military force. However, domination can also be achieved by direct military force.

The title of King of the Universe appeared in Ancient Mesopotamia as a title of great prestige claiming world domination, being used by powerful monarchs, starting with the Akkadian emperor Sargon (2334–2284 BC) and it was used in a succession of later empires claiming symbolical descent from Sargon's Akkadian Empire. During the Early Dynastic Period in Mesopotamia (c. 2900–2350 BC), the rulers of the various city-states (the most prominent being Ur, Uruk, Lagash, Umma and Kish) in the region would often launch invasions into regions and cities far from their own, at most times with negligible consequences for themselves, in order to establish temporary and small empires to either gain or keep a superior position relative to the other city-states. Eventually this quest to be more prestigious and powerful than the other city-states resulted in a general ambition for universal rule. Since Mesopotamia was equated to correspond to the entire world and Sumerian cities had been built far and wide (cities the like of Susa, Mari and Assur were located near the perceived corners of the world) it seemed possible to reach the edges of the world (at this time thought to be the lower sea, the Persian gulf, and the upper sea, the Mediterranean).

The title šar kiššatim was perhaps most prominently used by the kings of the Neo-Assyrian Empire, more than a thousand years after the fall of the Akkadian Empire.

After taking Babylon and defeat the Neo-Babylonian Empire, Cyrus the Great proclaimed himself "king of Babylon, king of Sumer and Akkad, king of the four corners of the world" in the famous Cyrus Cylinder, an inscription deposited in the foundations of the Esagila temple dedicated to the chief Babylonian god, Marduk. Cyrus the Great's dominions composed the largest empire the world had ever seen to that point, spanning from the Mediterranean Sea and Hellespont in the west to the Indus River in the east and Iranian philosophy, literature and religion played dominant roles in world events for the next millennium, like the Cyrus Cylinder as the oldest-known declaration of human rights. Before Cyrus and his army crossed the river Araxes to battle with the Armenians, he installed his son Cambyses II as king in case he should not return from battle. However, once Cyrus had crossed the Aras River, he had a vision in which Darius had wings atop his shoulders and stood upon the confines of Europe and Asia (the known world). When Cyrus awoke from the dream, he inferred it as a great danger to the future security of the empire, as it meant that Darius would one day rule the whole world. However, his son Cambyses was the heir to the throne, not Darius, causing Cyrus to wonder if Darius was forming treasonable and ambitious designs. This led Cyrus to order Hystaspes to go back to Persis and watch over his son strictly, until Cyrus himself returned. In many cuneiform inscriptions, like Behistun Inscription, Darius the Great denote his achievements, he presents himself as a devout believer of Ahura Mazda, perhaps even convinced that he had a divine right to rule over the world, believing that because he lived righteously by Asha, Ahura Mazda supported him as a Virtuos monarch and appointed him to rule the Achaemenid Empire and their global projection, while believing that each rebellion in his kingdom was the work of druj, the enemy of Asha, due to Dualist beliefs.

In the 4th century BCE, Alexander the Great notably expressed a desire to conquer the world, and a legend persists that after he completed his military conquest of the known ancient world, he "wept because he had no more worlds to conquer", as he was unaware of China farther to the east and had no way to know about civilizations in the Americas.

After the collapse of Macedonian Empire, the Seleucid Empire appeared with claims to world rule in their imperial ideology, as Antiochus I Soter claimed the ancient Mesopotamian title King of the Universe. However, it didn't reflect realistic Seleucid imperial ambitions at this point after the treaty of peace of Seleucus I Nicator with the Mauryans had set a limit to eastern expansion, and Antiochus ceding the lands west of Thrace to the Antigonids.

On the Indosphere, Bharata Chakravartin was the first chakravartin (universal emperor, ruler of rulers or possessor of chakra) of Avasarpini (present half time cycle as per Jain cosmology). In a Jain legend, Yasasvati Devi, senior-most queen of Rishabhanatha (first Jain tirthankara), saw four auspicious dreams one night. She saw the sun and the moon, the Mount Meru, the lake with swans, earth and the ocean. Rishabhanatha explained her that these dreams meant that a chakravartin ruler will be born to them who will conquer whole of the world. Then, Bharata, a Kshatriya from Ikshvaku dynasty, was born to them on the ninth day of the dark half of the month of Chaitra. He is said to have conquered all the six parts of the world, during his digvijaya (winning six divisions of earth in all directions), and to have engaged in a fight with Bahubali, his brother, to conquer the last remaining city. The ancient name of India was named "Bhāratavarsha" or "Bhārata" or "Bharata-bhumi" after him. In the Hindu text, Skanda Purana (chapter 37) it is stated that "Rishabhanatha was the son of Nabhiraja, and Rishabha had a son named Bharata, and after the name of this Bharata, this country is known as Bharata-varsha." After completing his world-conquest, he is said to have proceeded for his capital Ayodhyapuri with a huge army and the divine chakra-ratna (spinning, disk-like super weapon with serrated edges). Also, there's a legend of the Maharaj Vikramaditya's Empire, which spread across Middle East and East Asia (reaching even modern Indonesia) as a great Hindu world emperor (Chakravarti), probably inspiring the imperial pretensions of Chandragupta II and Skandagupta, as the term Vikramaditya is also used as a title by several Hindu monarchs. According to P.N. Oak and Stephen Knapp, king Vikrama’s empire extended up to Europe and whole Jambudweep (Asia) . But, according to most historical texts, his kingdom was located in the present-day northern India and Pakistan, implying that the historic Vikramaditya only ruled on Bharat until River Indus as per Bhavishya Purana. So, there is no epigraphic evidence to suggest that his rule extended to Europe, Arabia, Central Asia or Southeast Asia (Sources of contemporary empires, like Parthians, Kushans, Chinese, Romans, Sassanids) don't mention an empire ruling from Arabia to Indonesia), and that part of his rule is considered to be legend rather than historical fact, lying in the fact that Indic religious conceptions of the Indian sub-continent as being "the world" (as how the term Jambudvipa is used broadly to the same), and how that translates into folk memories. However, the Mahabharata or Somadeva's Kathasaritasagara has pretensions of world ruling, as performing some mystic ritual and virtues would be a signal of becoming emperor of the whole world, as Dharma has a universal jurisdiction in all the cosmos. In which there was a time when King Yudhisthira ruled over "the world". As From Śuciratha will come the son named Vṛṣṭimān, and his son, Suṣeṇa, will be the emperor of the entire world. Also there are signs in Bāṇabhaṭṭa that will shall arise an emperor named Harsha, who will rule over all the continents like Harishchandra, who will conquer the world like Mandhatr. But, the world, in the time of Ramayana in the 12th millennium BCE and Mahabharata in the 5th millennium BCE was only India. Some pan-indian empires, like Maurya Empire, were seeking the world domination (first of the known ancient world by indian in the Akhand Bharat, and then enter in conflict with Seleucid Empire), as Ashoka the great was a devout Buddhist and wanted to stablish it as a world religion. Also, the first references to a Chakravala Chakravartin (an emperor who rules over all four of the continents) appear in monuments from the time of the early Maurya Empire, in the 4th to 3rd century BCE, in reference to Chandragupta Maurya and his grandson Ashoka.

On the Sinosphere, one of the consequences of the Mandate of Heaven in Imperial China was the claim of the Emperor of China as Son of Heaven who ruled tianxia (meanint "all under heaven", closely associated with civilization and order in classical Chinese philosophy), which in English can be transliterated as "ruler of the whole world", being equivalent to the concept of a universal monarch. The title was interpreted literally only in China and Japan, whose monarchs were referred to as demigods, deities, or "living gods", chosen by the gods and goddesses of heaven. The theory, from Confucian bureaucracy, behind this was that the Chinese emperor acted as the autocrat of all under Heaven and held a mandate to rule over everyone else in the world; but only as long as he served the people well. If the quality of rule became questionable because of repeated natural disasters such as flood or famine, or for other reasons, then rebellion was justified. This important concept legitimized the dynastic cycle or the change of dynasties. The center of this world view was not exclusionary in nature, and outer groups, such as ethnic minorities and foreign people, who accepted the mandate of the Chinese Emperor (through annexation or being Tributary state of China) were themselves received and included into the Chinese tianxia (in which equates China as "everything under the sky"), as it presupposed "inclusion of all" and implied acceptance of the world's diversities, emphasizing harmonious reciprocal dependence and ruled by virtue as a means for lasting peace. Although in practice there would be areas of the known world which were not under the control of the Chinese monarch ("barbarians"), in Chinese political theory the rulers of those areas derived their power from the Chinese monarch (Sinocentrism). This principle was exemplified with Qin Shi Huang's goal to "unify all under Heaven", which was, in fact, representative of his desire to control and expand Chinese territory to act as an actual geographic entity, as consecuence of existing many of feudal states that had shared cultural and economic interests, so the concept of a great nation centered on the Yellow River Plain (the known world, both Han or Non-Han in Hua–Yi distinction) gradually expanded and the equivalence of tianxia with the Chinese nation evolved due to the feudal practice of conferring land. For the emperors of the central kingdom of China, the world can be roughly divided into two broad and simple categories: civilization and non-civilization, which means the people who have accepted the emperor's supremacy, the Heavenly virtue and its principle, and the people who have not accepted it; then, they recognized their country as the only true civilization in all respects, starting with their geography and including all the known world in a Celestial Empire. China's neighbors were obliged to pay their respects to the 'excellent' Chinese emperors within these boundaries on a regular basis. It can be said that this was the most important element of the East Asian order, which was implicit in the name of Celestial Empire in the past. In the 7th century during the Tang dynasty, some northern tribes of Turkic origin, after being made vassal (as consecuence of Tang campaign against the Eastern Turks), referred to the Emperor Taizong as the "Khan of Heaven". Also The Chinese emperor exercised power over the surrounding dynasty under the name of Celestial Empire. Especially in the case of kings of ancient Korea, it was the subject of the Chinese emperor. The idea of the absolute authority of the Chinese emperor and the extension of tianxia by the assimilation of vassal states began to fade with the Opium Wars, as China was made to refer to Great Britain as a "sovereign nation", equal to itself, it to establish a foreign affairs bureau and accommodate to Westphalian sovereignty of Western nations' system of international affairs during New Imperialism.

On Sasanian Empire, the use of the mythological Kayanian title of kay, first used by Yazdegerd II and reached its zenith under Peroz I, was due to a shift in the political perspective of the Sasanian Empire. Originally disposed towards the west against their rivals from the Byzantine Empire, this now changed to the east against Hephthalites. The war against the Hunnic tribes (Iranian Huns) may have awakened the mythical rivalry existing between the Iranian Kayanian rulers (mythical kings of the legendary Avestan dynasty) and their Turanian enemies, which is demonstrated in the Younger Avesta. Based on the legend of the Iranian hero-king Fereydun (Frēdōn in Middle Persian), who divided his kingdom between his three sons: his eldest son Salm received the empire of the west, "Rûm" (more generally meaning the Roman Empire, the Greco-Roman world, or just "the West"); the second eldest Tur received the empire of the east, Turān (all the lands north and east of the Amu Darya, as far as China); and the youngest, Iraj, received the heartland of the empire, Iran. So, the Sasanians Shahanshah may have believed themselves to be the heirs of the Fereydun and Iraj (reinforced because they were Ahura Mazda's worshippers), and so possibly considered both the Byzantine domains in west and the eastern domains of the Hephthalites as belonging to Iran, and therefore have been symbolically asserting their rights over these lands of both Hemispheres of Earth by assuming the title of kay.

On the Mongol Empire, Genghis Khan genuinely believed that it was his destiny to conquer the world for his god, Tengri, having a mission of bringing the rest of the world under one sword. This was based in his shamanic beliefs of the Great Blue Sky that spans the world, deriving his mandate for a world empire from this universal divinity, being close to unify Eurasia into a world empire under the shamanic umbrella. Also, Temujin took name "Genghis Khan", which means Universal Ruler, then, his sons and grandsons took up challenge of world conquest.

The fourth Mughal emperor styled himself Jahangir, meaning "world conqueror", and her wife Mehr-un-Nissa being awarded with the title of Nur Jahan ('Light of the World').

The Ottoman Empire had claims of world domination through Ottoman Caliphate. The Süleyman the Magnificent's Venetian helmet was an elaborate headpiece designed to project the sultan's power in the context of the Ottoman–Habsburg rivalry. Meaning The four floors of the Crown also represent Solomon's goal of world conquest—reigning the North, the South, the East, and the West—as well as the Pope's famous triple crown and the Holy Roman Empire two years ago. It was a reference to Charles V, who was crowned as the German Emperor, and also the three-tiered tiara worn by the Pope Clement VII.

However, with the full size and scope of the world known, it has been said that "world domination is an impossible goal", and specifically that "no single nation however big and powerful can dominate a world" of well over a hundred interdependent nations and billions of people.

An opposite view was expressed by Hans Morgenthau in 1948. He stressed that the mechanical development of weapons, transportation, and communication makes "the conquest of the world technically possible, and they make it technically possible to keep the world in that conquered state." He argues that a lack of such infrastructure explains why great ancient empires, though vast, failed to complete the universal conquest of their world and perpetuate the conquest. "Today no technological obstacle stands in the way of a world-wide empire," as "modern technology makes it possible to extend the control of mind and action to every corner of the globe regardless of geography and season." Morgenthau continued on the technological progress:

It has also given total war that terrifying, world-embracing impetus which seems to be satisfied with nothing less than world dominion... The machine age begets its own triumphs, each forward step calling forth two or more on the road of technological progress. It also begets its own victories, military and political; for with the ability to conquer the world and keep it conquered, it creates the will to conquer it.

In the early 17th century, Sir Walter Raleigh proposed that world domination could be achieved through control of the oceans, writing that "whosoever commands the sea commands the trade; whosoever commands the trade of the world commands the riches of the world, and consequently the world itself". In 1919, Halford Mackinder offered another influential theory for a route to world domination, writing:

Who rules East Europe commands the Heartland;
Who rules the Heartland commands the World-Island;
Who rules the World-Island commands the World.

While Mackinder's "Heartland Theory" initially received little attention outside geography, it later exercised some influence on the foreign policies of world powers seeking to obtain the control suggested by the theory. Impressed with the swift opening of World War II, Derwent Whittlesey wrote in 1942:

The swift march of conquest stunned or dazzled the onlookers... The grandiose concept of the world domination became possible as a practical objective only with the rise of science and its application to mechanical invention. By these means the earth’s scattered land units and territories became accessible and complementary to each other, and for the first time the world state, so long a futile medieval ideal, became a goal that might conceivably be reached.

Yet before the entrance of the United States into this War and with Isolationism still intact, U.S. strategist Hanson W. Baldwin had projected that "[t]omorrow air bases may be the highroad to power and domination... Obviously it is only by air bases ... that power exercised in the sovereign skies above a nation can be stretched far beyond its shores... Perhaps... future acquisitions of air bases ... can carry the voice of America through the skies to the ends of the earth.

Some proponents of ideologies (communism, fascism, Nazism, and socialism) actively pursue the goal of establishing a form of government consistent with their political beliefs, or assert that the world is moving "naturally" towards the adoption of a particular form of government (or self), authoritarian or anti-authoritarian. These proposals are not concerned with a particular nation achieving world domination, but with all nations conforming to a particular social or economic model. A goal of world domination can be to establish a world government, a single common political authority for all of humanity. The period of the Cold War, in particular, is considered to be a period of intense ideological polarization, given the existence of two rival blocs—the capitalist West and the communist East—that each expressed the hope of seeing the triumph of their ideology over that of the enemy. The ultimate end of such a triumph would be that one ideology or the other would become the sole governing ideology in the world.

In certain religions, some adherents may also seek the conversion (peaceful or forced) of as many people as possible to their own religion, without restrictions of national or ethnic origin. This type of spiritual domination is usually seen as distinct from the temporal dominion, although there have been instances of efforts begun as holy wars devolving into the pursuit of wealth, resources, and territory. Some Christian groups teach that a false religion, led by false prophets who achieve world domination by inducing nearly universal worship of a false deity, is a prerequisite to end times described in the Book of Revelation. As one author put it, "[i]f world domination is to be obtained, the masses of little people must be brought on board with religion".

In some instances, speakers have accused nations or ideological groups of seeking world domination, even where those entities have denied that this was their goal. For example, J. G. Ballard quoted Aldous Huxley as having said of the United States entering the First World War, "I dread the inevitable acceleration of American world domination which will be the result of it all...Europe will no longer be Europe". In 2012, politician and critic of Islam Geert Wilders characterized Islam as "an ideology aiming for world domination rather than a religion", and in 2008 characterized the 2008 Israel–Gaza conflict as a proxy action by Islam against the West, contending that "[t]he end of Israel would not mean the end of our problems with Islam, but only... the start of the final battle for world domination".

Neurophilosophy

From Wikipedia, the free encyclopedia https://en.wikipedia.org/wiki/Neurophilosophy ...