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Eternal oblivion (also referred to as non-existence or nothingness) is the philosophical or religious concept of one's consciousness forever ceasing upon death. This concept is mostly associated with religious skepticism, secular humanism and atheism. Unconsciousness and nonexistence after death is also believed by some religious groups like Jehovah's Witnesses. However they do not believe that death is necessarily the end since they believe in the universal resurrection.

According to most modern neuroscience theories of consciousness, the brain is the basis of subjective experience, agency, self-awareness, and awareness of the surrounding natural world. When brain death occurs, all brain function forever ceases. Many neuroscientists and neurophilosophers such as Daniel Dennett who believe that death is a forever cessation of consciousness also believe that consciousness is dependent upon the functioning of the brain. Scientific research has discovered that some areas of the brain, like the reticular activating system or the thalamus, appear to be necessary for consciousness, because dysfunction of or damage to these structures causes a loss of consciousness.

Through a naturalist analysis of the mind (an approach adopted by many philosophers of mind and neuroscientists), it is regarded as being dependent on the brain, as shown from the various effects of brain damage.

In philosophy