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Thursday, May 23, 2024

Medicine

From Wikipedia, the free encyclopedia
https://en.wikipedia.org/wiki/Medicine
Flag of World Health Organization featuring Rod of Asclepius, a common symbol for medicine and health care

Medicine is the science and practice of caring for patients, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others.

Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of creativity and skill), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, or an ancient philosopher and physician would apply bloodletting according to the theories of humorism. In recent centuries, since the advent of modern science, most medicine has become a combination of art and science (both basic and applied, under the umbrella of medical science). For example, while stitching technique for sutures is an art learned through practice, knowledge of what happens at the cellular and molecular level in the tissues being stitched arises through science.

Prescientific forms of medicine, now known as traditional medicine or folk medicine, remain commonly used in the absence of scientific medicine and are thus called alternative medicine. Alternative treatments outside of scientific medicine with ethical, safety and efficacy concerns are termed quackery.

Etymology

Medicine (UK: /ˈmɛdsɪn/ , US: /ˈmɛdɪsɪn/ ) is the science and practice of the diagnosis, prognosis, treatment, and prevention of disease. The word "medicine" is derived from Latin medicus, meaning "a physician".

Clinical practice

Oil painting of medicine in the age of colonialism
The Doctor by Sir Luke Fildes (1891)
Elizabeth Blackwell, the first female physician in the United States graduated from SUNY Upstate (1847)

Medical availability and clinical practice vary across the world due to regional differences in culture and technology. Modern scientific medicine is highly developed in the Western world, while in developing countries such as parts of Africa or Asia, the population may rely more heavily on traditional medicine with limited evidence and efficacy and no required formal training for practitioners.

In the developed world, evidence-based medicine is not universally used in clinical practice; for example, a 2007 survey of literature reviews found that about 49% of the interventions lacked sufficient evidence to support either benefit or harm.

In modern clinical practice, physicians and physician assistants personally assess patients to diagnose, prognose, treat, and prevent disease using clinical judgment. The doctor-patient relationship typically begins with an interaction with an examination of the patient's medical history and medical record, followed by a medical interview and a physical examination. Basic diagnostic medical devices (e.g., stethoscope, tongue depressor) are typically used. After examining for signs and interviewing for symptoms, the doctor may order medical tests (e.g., blood tests), take a biopsy, or prescribe pharmaceutical drugs or other therapies. Differential diagnosis methods help to rule out conditions based on the information provided. During the encounter, properly informing the patient of all relevant facts is an important part of the relationship and the development of trust. The medical encounter is then documented in the medical record, which is a legal document in many jurisdictions. Follow-ups may be shorter but follow the same general procedure, and specialists follow a similar process. The diagnosis and treatment may take only a few minutes or a few weeks, depending on the complexity of the issue.

The components of the medical interview and encounter are:

  • Chief complaint (CC): the reason for the current medical visit. These are the symptoms. They are in the patient's own words and are recorded along with the duration of each one. Also called chief concern or presenting complaint.
  • Current activity: occupation, hobbies, what the patient actually does.
  • Family history (FH): listing of diseases in the family that may impact the patient. A family tree is sometimes used.
  • History of present illness (HPI): the chronological order of events of symptoms and further clarification of each symptom. Distinguishable from history of previous illness, often called past medical history (PMH). Medical history comprises HPI and PMH.
  • Medications (Rx): what drugs the patient takes including prescribed, over-the-counter, and home remedies, as well as alternative and herbal medicines or remedies. Allergies are also recorded.
  • Past medical history (PMH/PMHx): concurrent medical problems, past hospitalizations and operations, injuries, past infectious diseases or vaccinations, history of known allergies.
  • Review of systems (ROS) or systems inquiry: a set of additional questions to ask, which may be missed on HPI: a general enquiry (have you noticed any weight loss, change in sleep quality, fevers, lumps and bumps? etc.), followed by questions on the body's main organ systems (heart, lungs, digestive tract, urinary tract, etc.).
  • Social history (SH): birthplace, residences, marital history, social and economic status, habits (including diet, medications, tobacco, alcohol).

The physical examination is the examination of the patient for medical signs of disease that are objective and observable, in contrast to symptoms that are volunteered by the patient and are not necessarily objectively observable. The healthcare provider uses sight, hearing, touch, and sometimes smell (e.g., in infection, uremia, diabetic ketoacidosis). Four actions are the basis of physical examination: inspection, palpation (feel), percussion (tap to determine resonance characteristics), and auscultation (listen), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments.

The clinical examination involves the study of:

It is to likely focus on areas of interest highlighted in the medical history and may not include everything listed above.

The treatment plan may include ordering additional medical laboratory tests and medical imaging studies, starting therapy, referral to a specialist, or watchful observation. A follow-up may be advised. Depending upon the health insurance plan and the managed care system, various forms of "utilization review", such as prior authorization of tests, may place barriers on accessing expensive services.

The medical decision-making (MDM) process includes the analysis and synthesis of all the above data to come up with a list of possible diagnoses (the differential diagnoses), along with an idea of what needs to be done to obtain a definitive diagnosis that would explain the patient's problem.

On subsequent visits, the process may be repeated in an abbreviated manner to obtain any new history, symptoms, physical findings, lab or imaging results, or specialist consultations.

Institutions

Color fresco of an ancient hospital setting
The Hospital of Santa Maria della Scala, fresco by Domenico di Bartolo, 1441–1442

Contemporary medicine is, in general, conducted within health care systems. Legal, credentialing, and financing frameworks are established by individual governments, augmented on occasion by international organizations, such as churches. The characteristics of any given health care system have a significant impact on the way medical care is provided.

From ancient times, Christian emphasis on practical charity gave rise to the development of systematic nursing and hospitals, and the Catholic Church today remains the largest non-government provider of medical services in the world. Advanced industrial countries (with the exception of the United States) and many developing countries provide medical services through a system of universal health care that aims to guarantee care for all through a single-payer health care system or compulsory private or cooperative health insurance. This is intended to ensure that the entire population has access to medical care on the basis of need rather than ability to pay. Delivery may be via private medical practices, state-owned hospitals and clinics, or charities, most commonly a combination of all three.

Most tribal societies provide no guarantee of healthcare for the population as a whole. In such societies, healthcare is available to those who can afford to pay for it, have self-insured it (either directly or as part of an employment contract), or may be covered by care financed directly by the government or tribe.

collection of glass bottles of different sizes
Modern drug ampoules

Transparency of information is another factor defining a delivery system. Access to information on conditions, treatments, quality, and pricing greatly affects the choice of patients/consumers and, therefore, the incentives of medical professionals. While the US healthcare system has come under fire for its lack of openness, new legislation may encourage greater openness. There is a perceived tension between the need for transparency on the one hand and such issues as patient confidentiality and the possible exploitation of information for commercial gain on the other.

The health professionals who provide care in medicine comprise multiple professions, such as medics, nurses, physiotherapists, and psychologists. These professions will have their own ethical standards, professional education, and bodies. The medical profession has been conceptualized from a sociological perspective.

Delivery

Provision of medical care is classified into primary, secondary, and tertiary care categories.

photograph of three nurses
Nurses in Kokopo, East New Britain, Papua New Guinea

Primary care medical services are provided by physicians, physician assistants, nurse practitioners, or other health professionals who have first contact with a patient seeking medical treatment or care. These occur in physician offices, clinics, nursing homes, schools, home visits, and other places close to patients. About 90% of medical visits can be treated by the primary care provider. These include treatment of acute and chronic illnesses, preventive care and health education for all ages and both sexes.

Secondary care medical services are provided by medical specialists in their offices or clinics or at local community hospitals for a patient referred by a primary care provider who first diagnosed or treated the patient. Referrals are made for those patients who required the expertise or procedures performed by specialists. These include both ambulatory care and inpatient services, emergency departments, intensive care medicine, surgery services, physical therapy, labor and delivery, endoscopy units, diagnostic laboratory and medical imaging services, hospice centers, etc. Some primary care providers may also take care of hospitalized patients and deliver babies in a secondary care setting.

Tertiary care medical services are provided by specialist hospitals or regional centers equipped with diagnostic and treatment facilities not generally available at local hospitals. These include trauma centers, burn treatment centers, advanced neonatology unit services, organ transplants, high-risk pregnancy, radiation oncology, etc.

Modern medical care also depends on information – still delivered in many health care settings on paper records, but increasingly nowadays by electronic means.

In low-income countries, modern healthcare is often too expensive for the average person. International healthcare policy researchers have advocated that "user fees" be removed in these areas to ensure access, although even after removal, significant costs and barriers remain.

Separation of prescribing and dispensing is a practice in medicine and pharmacy in which the physician who provides a medical prescription is independent from the pharmacist who provides the prescription drug. In the Western world there are centuries of tradition for separating pharmacists from physicians. In Asian countries, it is traditional for physicians to also provide drugs.

Branches

Drawing by Marguerite Martyn (1918) of a visiting nurse in St. Louis, Missouri, with medicine and babies

Working together as an interdisciplinary team, many highly trained health professionals besides medical practitioners are involved in the delivery of modern health care. Examples include: nurses, emergency medical technicians and paramedics, laboratory scientists, pharmacists, podiatrists, physiotherapists, respiratory therapists, speech therapists, occupational therapists, radiographers, dietitians, and bioengineers, medical physicists, surgeons, surgeon's assistant, surgical technologist.

The scope and sciences underpinning human medicine overlap many other fields. A patient admitted to the hospital is usually under the care of a specific team based on their main presenting problem, e.g., the cardiology team, who then may interact with other specialties, e.g., surgical, radiology, to help diagnose or treat the main problem or any subsequent complications/developments.

Physicians have many specializations and subspecializations into certain branches of medicine, which are listed below. There are variations from country to country regarding which specialties certain subspecialties are in.

The main branches of medicine are:

Basic sciences

  • Anatomy is the study of the physical structure of organisms. In contrast to macroscopic or gross anatomy, cytology and histology are concerned with microscopic structures.
  • Biochemistry is the study of the chemistry taking place in living organisms, especially the structure and function of their chemical components.
  • Biomechanics is the study of the structure and function of biological systems by means of the methods of Mechanics.
  • Biophysics is an interdisciplinary science that uses the methods of physics and physical chemistry to study biological systems.
  • Biostatistics is the application of statistics to biological fields in the broadest sense. A knowledge of biostatistics is essential in the planning, evaluation, and interpretation of medical research. It is also fundamental to epidemiology and evidence-based medicine.
  • Cytology is the microscopic study of individual cells.
Louis Pasteur, as portrayed in his laboratory, 1885 by Albert Edelfelt
Statue of Robert Koch in Berlin

Specialties

In the broadest meaning of "medicine", there are many different specialties. In the UK, most specialities have their own body or college, which has its own entrance examination. These are collectively known as the Royal Colleges, although not all currently use the term "Royal". The development of a speciality is often driven by new technology (such as the development of effective anaesthetics) or ways of working (such as emergency departments); the new specialty leads to the formation of a unifying body of doctors and the prestige of administering their own examination.

Within medical circles, specialities usually fit into one of two broad categories: "Medicine" and "Surgery". "Medicine" refers to the practice of non-operative medicine, and most of its subspecialties require preliminary training in Internal Medicine. In the UK, this was traditionally evidenced by passing the examination for the Membership of the Royal College of Physicians (MRCP) or the equivalent college in Scotland or Ireland. "Surgery" refers to the practice of operative medicine, and most subspecialties in this area require preliminary training in General Surgery, which in the UK leads to membership of the Royal College of Surgeons of England (MRCS). At present, some specialties of medicine do not fit easily into either of these categories, such as radiology, pathology, or anesthesia. Most of these have branched from one or other of the two camps above; for example anaesthesia developed first as a faculty of the Royal College of Surgeons (for which MRCS/FRCS would have been required) before becoming the Royal College of Anaesthetists and membership of the college is attained by sitting for the examination of the Fellowship of the Royal College of Anesthetists (FRCA).

Surgical specialty

Surgeons in an operating room

Surgery is an ancient medical specialty that uses operative manual and instrumental techniques on a patient to investigate or treat a pathological condition such as disease or injury, to help improve bodily function or appearance or to repair unwanted ruptured areas (for example, a perforated ear drum). Surgeons must also manage pre-operative, post-operative, and potential surgical candidates on the hospital wards. In some centers, anesthesiology is part of the division of surgery (for historical and logistical reasons), although it is not a surgical discipline. Other medical specialties may employ surgical procedures, such as ophthalmology and dermatology, but are not considered surgical sub-specialties per se.

Surgical training in the U.S. requires a minimum of five years of residency after medical school. Sub-specialties of surgery often require seven or more years. In addition, fellowships can last an additional one to three years. Because post-residency fellowships can be competitive, many trainees devote two additional years to research. Thus in some cases surgical training will not finish until more than a decade after medical school. Furthermore, surgical training can be very difficult and time-consuming.

Surgical subspecialties include those a physician may specialize in after undergoing general surgery residency training as well as several surgical fields with separate residency training. Surgical subspecialties that one may pursue following general surgery residency training: 

Other surgical specialties within medicine with their own individual residency training:

Internal medicine specialty

Internal medicine is the medical specialty dealing with the prevention, diagnosis, and treatment of adult diseases. According to some sources, an emphasis on internal structures is implied. In North America, specialists in internal medicine are commonly called "internists". Elsewhere, especially in Commonwealth nations, such specialists are often called physicians. These terms, internist or physician (in the narrow sense, common outside North America), generally exclude practitioners of gynecology and obstetrics, pathology, psychiatry, and especially surgery and its subspecialities.

Because their patients are often seriously ill or require complex investigations, internists do much of their work in hospitals. Formerly, many internists were not subspecialized; such general physicians would see any complex nonsurgical problem; this style of practice has become much less common. In modern urban practice, most internists are subspecialists: that is, they generally limit their medical practice to problems of one organ system or to one particular area of medical knowledge. For example, gastroenterologists and nephrologists specialize respectively in diseases of the gut and the kidneys.

In the Commonwealth of Nations and some other countries, specialist pediatricians and geriatricians are also described as specialist physicians (or internists) who have subspecialized by age of patient rather than by organ system. Elsewhere, especially in North America, general pediatrics is often a form of primary care.

There are many subspecialities (or subdisciplines) of internal medicine:

Training in internal medicine (as opposed to surgical training), varies considerably across the world: see the articles on medical education for more details. In North America, it requires at least three years of residency training after medical school, which can then be followed by a one- to three-year fellowship in the subspecialties listed above. In general, resident work hours in medicine are less than those in surgery, averaging about 60 hours per week in the US. This difference does not apply in the UK where all doctors are now required by law to work less than 48 hours per week on average.

Diagnostic specialties

Other major specialties

The following are some major medical specialties that do not directly fit into any of the above-mentioned groups:

  • Anesthesiology (also known as anaesthetics): concerned with the perioperative management of the surgical patient. The anesthesiologist's role during surgery is to prevent derangement in the vital organs' (i.e. brain, heart, kidneys) functions and postoperative pain. Outside of the operating room, the anesthesiology physician also serves the same function in the labor and delivery ward, and some are specialized in critical medicine.
  • Emergency medicine is concerned with the diagnosis and treatment of acute or life-threatening conditions, including trauma, surgical, medical, pediatric, and psychiatric emergencies.
  • Family medicine, family practice, general practice or primary care is, in many countries, the first port-of-call for patients with non-emergency medical problems. Family physicians often provide services across a broad range of settings including office based practices, emergency department coverage, inpatient care, and nursing home care.
Gynecologist Michel Akotionga of Ouagadougou, Burkina Faso

Interdisciplinary fields

Some interdisciplinary sub-specialties of medicine include:

Education and legal controls

Medical students learning about stitches

Medical education and training varies around the world. It typically involves entry level education at a university medical school, followed by a period of supervised practice or internship, or residency. This can be followed by postgraduate vocational training. A variety of teaching methods have been employed in medical education, still itself a focus of active research. In Canada and the United States of America, a Doctor of Medicine degree, often abbreviated M.D., or a Doctor of Osteopathic Medicine degree, often abbreviated as D.O. and unique to the United States, must be completed in and delivered from a recognized university.

Since knowledge, techniques, and medical technology continue to evolve at a rapid rate, many regulatory authorities require continuing medical education. Medical practitioners upgrade their knowledge in various ways, including medical journals, seminars, conferences, and online programs. A database of objectives covering medical knowledge, as suggested by national societies across the United States, can be searched at http://data.medobjectives.marian.edu/ Archived 4 October 2018 at the Wayback Machine.

Headquarters of the Organización Médica Colegial de España, which regulates the medical profession in Spain

In most countries, it is a legal requirement for a medical doctor to be licensed or registered. In general, this entails a medical degree from a university and accreditation by a medical board or an equivalent national organization, which may ask the applicant to pass exams. This restricts the considerable legal authority of the medical profession to physicians that are trained and qualified by national standards. It is also intended as an assurance to patients and as a safeguard against charlatans that practice inadequate medicine for personal gain. While the laws generally require medical doctors to be trained in "evidence based", Western, or Hippocratic Medicine, they are not intended to discourage different paradigms of health.

In the European Union, the profession of doctor of medicine is regulated. A profession is said to be regulated when access and exercise is subject to the possession of a specific professional qualification. The regulated professions database contains a list of regulated professions for doctor of medicine in the EU member states, EEA countries and Switzerland. This list is covered by the Directive 2005/36/EC.

Doctors who are negligent or intentionally harmful in their care of patients can face charges of medical malpractice and be subject to civil, criminal, or professional sanctions.

Medical ethics

A 12th-century Byzantine manuscript of the Hippocratic Oath

Medical ethics is a system of moral principles that apply values and judgments to the practice of medicine. As a scholarly discipline, medical ethics encompasses its practical application in clinical settings as well as work on its history, philosophy, theology, and sociology. Six of the values that commonly apply to medical ethics discussions are:

  • autonomy – the patient has the right to refuse or choose their treatment. (Latin: Voluntas aegroti suprema lex.)
  • beneficence – a practitioner should act in the best interest of the patient. (Latin: Salus aegroti suprema lex.)
  • justice – concerns the distribution of scarce health resources, and the decision of who gets what treatment (fairness and equality).
  • non-maleficence – "first, do no harm" (Latin: primum non-nocere).
  • respect for persons – the patient (and the person treating the patient) have the right to be treated with dignity.
  • truthfulness and honesty – the concept of informed consent has increased in importance since the historical events of the Doctors' Trial of the Nuremberg trials, Tuskegee syphilis experiment, and others.

Values such as these do not give answers as to how to handle a particular situation, but provide a useful framework for understanding conflicts. When moral values are in conflict, the result may be an ethical dilemma or crisis. Sometimes, no good solution to a dilemma in medical ethics exists, and occasionally, the values of the medical community (i.e., the hospital and its staff) conflict with the values of the individual patient, family, or larger non-medical community. Conflicts can also arise between health care providers, or among family members. For example, some argue that the principles of autonomy and beneficence clash when patients refuse blood transfusions, considering them life-saving; and truth-telling was not emphasized to a large extent before the HIV era.

History

Statuette of ancient Egyptian physician Imhotep, the first physician from antiquity known by name

Ancient world

Prehistoric medicine incorporated plants (herbalism), animal parts, and minerals. In many cases these materials were used ritually as magical substances by priests, shamans, or medicine men. Well-known spiritual systems include animism (the notion of inanimate objects having spirits), spiritualism (an appeal to gods or communion with ancestor spirits); shamanism (the vesting of an individual with mystic powers); and divination (magically obtaining the truth). The field of medical anthropology examines the ways in which culture and society are organized around or impacted by issues of health, health care and related issues.

The earliest known medical texts in the world were found in the ancient Syrian city of Ebla and date back to 2500 BCE. Other early records on medicine have been discovered from ancient Egyptian medicine, Babylonian Medicine, Ayurvedic medicine (in the Indian subcontinent), classical Chinese medicine (predecessor to the modern traditional Chinese medicine), and ancient Greek medicine and Roman medicine.

In Egypt, Imhotep (3rd millennium BCE) is the first physician in history known by name. The oldest Egyptian medical text is the Kahun Gynaecological Papyrus from around 2000 BCE, which describes gynaecological diseases. The Edwin Smith Papyrus dating back to 1600 BCE is an early work on surgery, while the Ebers Papyrus dating back to 1500 BCE is akin to a textbook on medicine.

In China, archaeological evidence of medicine in Chinese dates back to the Bronze Age Shang Dynasty, based on seeds for herbalism and tools presumed to have been used for surgery. The Huangdi Neijing, the progenitor of Chinese medicine, is a medical text written beginning in the 2nd century BCE and compiled in the 3rd century.

In India, the surgeon Sushruta described numerous surgical operations, including the earliest forms of plastic surgery. Earliest records of dedicated hospitals come from Mihintale in Sri Lanka where evidence of dedicated medicinal treatment facilities for patients are found.

Mosaic on the floor of the Asclepieion of Kos, depicting Hippocrates, with Asklepius in the middle (2nd–3rd century)

In Greece, the ancient Greek physician Hippocrates, the "father of modern medicine", laid the foundation for a rational approach to medicine. Hippocrates introduced the Hippocratic Oath for physicians, which is still relevant and in use today, and was the first to categorize illnesses as acute, chronic, endemic and epidemic, and use terms such as, "exacerbation, relapse, resolution, crisis, paroxysm, peak, and convalescence". The Greek physician Galen was also one of the greatest surgeons of the ancient world and performed many audacious operations, including brain and eye surgeries. After the fall of the Western Roman Empire and the onset of the Early Middle Ages, the Greek tradition of medicine went into decline in Western Europe, although it continued uninterrupted in the Eastern Roman (Byzantine) Empire.

Most of our knowledge of ancient Hebrew medicine during the 1st millennium BC comes from the Torah, i.e. the Five Books of Moses, which contain various health related laws and rituals. The Hebrew contribution to the development of modern medicine started in the Byzantine Era, with the physician Asaph the Jew.

Middle Ages

A manuscript of Al-Risalah al-Dhahabiah by Ali al-Ridha, the eighth Imam of Shia Muslims. The text says: "Golden dissertation in medicine which is sent by Imam Ali ibn Musa al-Ridha, peace be upon him, to al-Ma'mun."

The concept of hospital as institution to offer medical care and possibility of a cure for the patients due to the ideals of Christian charity, rather than just merely a place to die, appeared in the Byzantine Empire.

Although the concept of uroscopy was known to Galen, he did not see the importance of using it to localize the disease. It was under the Byzantines with physicians such of Theophilus Protospatharius that they realized the potential in uroscopy to determine disease in a time when no microscope or stethoscope existed. That practice eventually spread to the rest of Europe.

After 750 CE, the Muslim world had the works of Hippocrates, Galen and Sushruta translated into Arabic, and Islamic physicians engaged in some significant medical research. Notable Islamic medical pioneers include the Persian polymath, Avicenna, who, along with Imhotep and Hippocrates, has also been called the "father of medicine". He wrote The Canon of Medicine which became a standard medical text at many medieval European universities, considered one of the most famous books in the history of medicine. Others include Abulcasis, Avenzoar, Ibn al-Nafis, and Averroes. Persian physician Rhazes was one of the first to question the Greek theory of humorism, which nevertheless remained influential in both medieval Western and medieval Islamic medicine. Some volumes of Rhazes's work Al-Mansuri, namely "On Surgery" and "A General Book on Therapy", became part of the medical curriculum in European universities. Additionally, he has been described as a doctor's doctor, the father of pediatrics, and a pioneer of ophthalmology. For example, he was the first to recognize the reaction of the eye's pupil to light. The Persian Bimaristan hospitals were an early example of public hospitals.

In Europe, Charlemagne decreed that a hospital should be attached to each cathedral and monastery and the historian Geoffrey Blainey likened the activities of the Catholic Church in health care during the Middle Ages to an early version of a welfare state: "It conducted hospitals for the old and orphanages for the young; hospices for the sick of all ages; places for the lepers; and hostels or inns where pilgrims could buy a cheap bed and meal". It supplied food to the population during famine and distributed food to the poor. This welfare system the church funded through collecting taxes on a large scale and possessing large farmlands and estates. The Benedictine order was noted for setting up hospitals and infirmaries in their monasteries, growing medical herbs and becoming the chief medical care givers of their districts, as at the great Abbey of Cluny. The Church also established a network of cathedral schools and universities where medicine was studied. The Schola Medica Salernitana in Salerno, looking to the learning of Greek and Arab physicians, grew to be the finest medical school in Medieval Europe.

Siena's Santa Maria della Scala Hospital, one of Europe's oldest hospitals. During the Middle Ages, the Catholic Church established universities to revive the study of sciences, drawing on the learning of Greek and Arab physicians in the study of medicine.

However, the fourteenth and fifteenth century Black Death devastated both the Middle East and Europe, and it has even been argued that Western Europe was generally more effective in recovering from the pandemic than the Middle East. In the early modern period, important early figures in medicine and anatomy emerged in Europe, including Gabriele Falloppio and William Harvey.

The major shift in medical thinking was the gradual rejection, especially during the Black Death in the 14th and 15th centuries, of what may be called the "traditional authority" approach to science and medicine. This was the notion that because some prominent person in the past said something must be so, then that was the way it was, and anything one observed to the contrary was an anomaly (which was paralleled by a similar shift in European society in general – see Copernicus's rejection of Ptolemy's theories on astronomy). Physicians like Vesalius improved upon or disproved some of the theories from the past. The main tomes used both by medicine students and expert physicians were Materia Medica and Pharmacopoeia.

Andreas Vesalius was the author of De humani corporis fabrica, an important book on human anatomy. Bacteria and microorganisms were first observed with a microscope by Antonie van Leeuwenhoek in 1676, initiating the scientific field microbiology. Independently from Ibn al-Nafis, Michael Servetus rediscovered the pulmonary circulation, but this discovery did not reach the public because it was written down for the first time in the "Manuscript of Paris" in 1546, and later published in the theological work for which he paid with his life in 1553. Later this was described by Renaldus Columbus and Andrea Cesalpino. Herman Boerhaave is sometimes referred to as a "father of physiology" due to his exemplary teaching in Leiden and textbook 'Institutiones medicae' (1708). Pierre Fauchard has been called "the father of modern dentistry".

Modern

Paul-Louis Simond injecting a plague vaccine in Karachi, 1898

Veterinary medicine was, for the first time, truly separated from human medicine in 1761, when the French veterinarian Claude Bourgelat founded the world's first veterinary school in Lyon, France. Before this, medical doctors treated both humans and other animals.

Modern scientific biomedical research (where results are testable and reproducible) began to replace early Western traditions based on herbalism, the Greek "four humours" and other such pre-modern notions. The modern era really began with Edward Jenner's discovery of the smallpox vaccine at the end of the 18th century (inspired by the method of variolation originated in ancient China), Robert Koch's discoveries around 1880 of the transmission of disease by bacteria, and then the discovery of antibiotics around 1900.

The post-18th century modernity period brought more groundbreaking researchers from Europe. From Germany and Austria, doctors Rudolf Virchow, Wilhelm Conrad Röntgen, Karl Landsteiner and Otto Loewi made notable contributions. In the United Kingdom, Alexander Fleming, Joseph Lister, Francis Crick and Florence Nightingale are considered important. Spanish doctor Santiago Ramón y Cajal is considered the father of modern neuroscience.

From New Zealand and Australia came Maurice Wilkins, Howard Florey, and Frank Macfarlane Burnet.

Others that did significant work include William Williams Keen, William Coley, James D. Watson (United States); Salvador Luria (Italy); Alexandre Yersin (Switzerland); Kitasato Shibasaburō (Japan); Jean-Martin Charcot, Claude Bernard, Paul Broca (France); Adolfo Lutz (Brazil); Nikolai Korotkov (Russia); Sir William Osler (Canada); and Harvey Cushing (United States).

As science and technology developed, medicine became more reliant upon medications. Throughout history and in Europe right until the late 18th century, not only plant products were used as medicine, but also animal (including human) body parts and fluids. Pharmacology developed in part from herbalism and some drugs are still derived from plants (atropine, ephedrine, warfarin, aspirin, digoxin, vinca alkaloids, taxol, hyoscine, etc.). Vaccines were discovered by Edward Jenner and Louis Pasteur.

The first antibiotic was arsphenamine (Salvarsan) discovered by Paul Ehrlich in 1908 after he observed that bacteria took up toxic dyes that human cells did not. The first major class of antibiotics was the sulfa drugs, derived by German chemists originally from azo dyes.

Packaging of cardiac medicine at the Star pharmaceutical factory in Tampere, Finland in 1953

Pharmacology has become increasingly sophisticated; modern biotechnology allows drugs targeted towards specific physiological processes to be developed, sometimes designed for compatibility with the body to reduce side-effects. Genomics and knowledge of human genetics and human evolution is having increasingly significant influence on medicine, as the causative genes of most monogenic genetic disorders have now been identified, and the development of techniques in molecular biology, evolution, and genetics are influencing medical technology, practice and decision-making.

Evidence-based medicine is a contemporary movement to establish the most effective algorithms of practice (ways of doing things) through the use of systematic reviews and meta-analysis. The movement is facilitated by modern global information science, which allows as much of the available evidence as possible to be collected and analyzed according to standard protocols that are then disseminated to healthcare providers. The Cochrane Collaboration leads this movement. A 2001 review of 160 Cochrane systematic reviews revealed that, according to two readers, 21.3% of the reviews concluded insufficient evidence, 20% concluded evidence of no effect, and 22.5% concluded positive effect.

Quality, efficiency, and access

Evidence-based medicine, prevention of medical error (and other "iatrogenesis"), and avoidance of unnecessary health care are a priority in modern medical systems. These topics generate significant political and public policy attention, particularly in the United States where healthcare is regarded as excessively costly but population health metrics lag similar nations.

Globally, many developing countries lack access to care and access to medicines. As of 2015, most wealthy developed countries provide health care to all citizens, with a few exceptions such as the United States where lack of health insurance coverage may limit access.

Applied science

From Wikipedia, the free encyclopedia
https://en.wikipedia.org/wiki/Applied_science
 
Applied science is the use of the scientific method and knowledge obtained via conclusions from the method to attain practical goals. It includes a broad range of disciplines such as engineering and medicine. Applied science is often contrasted with basic science, which is focused on advancing scientific theories and laws that explain and predict natural or other phenomena.

Applied science can also apply formal science, such as statistics and probability theory, as in epidemiology. Genetic epidemiology is an applied science applying both biological and statistical methods. Applied science can also apply social science, such as application of psychology in applied psychology, criminology, and law.

Historical context

Historians would want to see how applied science has evolved over time. In particular, how societies started applying scientific principles to practical problems, and how this practice changed over centuries. Exploring historical examples of applied science, such as the development of engineering techniques in ancient civilizations or the emergence of modern medical practices, would be valuable.

Applied research

Applied research is the practical application of science. It accesses and uses accumulated theories, knowledge, methods, and techniques, for a specific state-, business-, or client-driven purpose. In contrast to engineering, applied research does not include analyses or optimization of business, economics, and costs. Applied research can be better understood in any area when contrasting it with, basic, or pure, research. Basic geography research strives to create new theories and methods that aid in the explanation of the processes that shape the spatial structure of physical or human environments. Rather, applied research utilizes the already existing geographical theories and methods to comprehend and address particular empirical issues. Applied research usually has specific commercial objectives related to products, procedures, or services. The comparison of pure research and applied research provides a basic framework and direction for businesses to follow.

Applied research deals with solving practical problems and generally employs empirical methodologies. Because applied research resides in the messy real world, strict research protocols may need to be relaxed. For example, it may be impossible to use a random sample. Thus, transparency in the methodology is crucial. Implications for interpretation of results brought about by relaxing an otherwise strict canon of methodology should also be considered.

Moreover, this type of research method applies natural sciences to human conditions:

  • Action Research: aids firms in identifying workable solutions to issues influencing them.
  • Evaluation Research: researchers examine available data to assist clients in making wise judgements.
  • Industrial Research: create new goods/services that will satisfy the demands of a target market. (Industrial development would be scaling up production of the new goods/services for mass consumption to satisfy the economic demand of the customers while maximizing the ratio of the good/service output rate to resource input rate, the ratio of good/service revenue to material & energy costs, and the good/service quality. Industrial development would be considered engineering. Industrial development would fall outside the scope of applied research.)

Since applied research has a provisional close-to-the-problem and close-to-the-data orientation, it may also use a more provisional conceptual framework such as working hypotheses or pillar questions. The OECD's Frascati Manual describes applied research as one of the three forms of research, along with basic research & experimental development.

Due to its practical focus, applied research information will be found in the literature associated with individual disciplines.

Branches

Applied science works as a system that branches into other fields of work that go more in depth of the system. Applied research is a method of problem solving and also practical in areas of science such as its presence in applied psychology. Applied psychology uses human behavior to grab information to be able locate a main focus in an area that can contribute to finding a resolution. More specific, this study is applied in the area of criminal psychology. With the knowledge obtained of applied research, studies are conducted on criminals alongside their behavior to apprehend them. Moreover, the research extends to criminal investigations. Under this category, research methods demonstrate an understanding of the scientific method and social research designs used in criminological research. These reach more branches along the procedure towards the investigations, alongside laws, policy, and criminological theory.

Engineering fields include thermodynamics, heat transfer, fluid mechanics, statics, dynamics, mechanics of materials, kinematics, electromagnetism, materials science, earth sciences, engineering physics. These fields are also within the scope of basic science.

Medical sciences, for instance medical microbiology, pharmaceutical research and clinical virology, are applied sciences that apply biology and chemistry toward medicine. Pharmaceutical development would fall within the scope of engineering.

In education

In Canada, the Netherlands and other places the Bachelor of Applied Science (BASc) is sometimes equivalent to the Bachelor of Engineering, and is classified as a professional degree. This is based on the age of the school where applied science used to include boiler making, surveying and engineering. There are also Bachelor of Applied Science degrees in Child Studies. The BASc tends to focus more on the application of the engineering sciences. In Australia and New Zealand, this degree is awarded in various fields of study and is considered a highly specialized professional degree.

In the United Kingdom's educational system, Applied Science refers to a suite of "vocational" science qualifications that run alongside "traditional" General Certificate of Secondary Education or A-Level Sciences. Applied Science courses generally contain more coursework (also known as portfolio or internally assessed work) compared to their traditional counterparts. These are an evolution of the GNVQ qualifications that were offered up to 2005. These courses regularly come under scrutiny and are due for review following the Wolf Report 2011; however, their merits are argued elsewhere.

In the United States, The College of William & Mary offers an undergraduate minor as well as Master of Science and Doctor of Philosophy degrees in "applied science". Courses and research cover varied fields including neuroscience, optics, materials science and engineering, nondestructive testing, and nuclear magnetic resonance. University of Nebraska–Lincoln offers a Bachelor of Science in applied science, an online completion Bachelor of Science in applied science and a Master of Applied Science. Course work is centered on science, agriculture and natural resources with a wide range of options including ecology, food genetics, entrepreneurship, economics, policy, animal science and plant science. In New York City, the Bloomberg administration awarded the consortium of Cornell-Technion $100 million in City capital to construct the universities' proposed Applied Sciences campus on Roosevelt Island.

Open-source hardware

From Wikipedia, the free encyclopedia
https://en.wikipedia.org/wiki/Open-source_hardware
The "open source hardware" logo proposed by OSHWA, one of the main defining organizations
The RepRap Mendel general-purpose 3D printer with the ability to make copies of most of its own structural parts

Open-source hardware (OSH, OSHW) consists of physical artifacts of technology designed and offered by the open-design movement. Both free and open-source software (FOSS) and open-source hardware are created by this open-source culture movement and apply a like concept to a variety of components. It is sometimes, thus, referred to as FOSH (free and open-source hardware). The term usually means that information about the hardware is easily discerned so that others can make it – coupling it closely to the maker movement. Hardware design (i.e. mechanical drawings, schematics, bills of material, PCB layout data, HDL source code and integrated circuit layout data), in addition to the software that drives the hardware, are all released under free/libre terms. The original sharer gains feedback and potentially improvements on the design from the FOSH community. There is now significant evidence that such sharing can drive a high return on investment for the scientific community.

It is not enough to merely use an open-source license; an open source product or project will follow open source principles, such as modular design and community collaboration.

Since the rise of reconfigurable programmable logic devices, sharing of logic designs has been a form of open-source hardware. Instead of the schematics, hardware description language (HDL) code is shared. HDL descriptions are commonly used to set up system-on-a-chip systems either in field-programmable gate arrays (FPGA) or directly in application-specific integrated circuit (ASIC) designs. HDL modules, when distributed, are called semiconductor intellectual property cores, also known as IP cores.

Open-source hardware also helps alleviate the issue of proprietary device drivers for the free and open-source software community, however, it is not a pre-requisite for it, and should not be confused with the concept of open documentation for proprietary hardware, which is already sufficient for writing FLOSS device drivers and complete operating systems. The difference between the two concepts is that OSH includes both the instructions on how to replicate the hardware itself as well as the information on communication protocols that the software (usually in the form of device drivers) must use in order to communicate with the hardware (often called register documentation, or open documentation for hardware), whereas open-source-friendly proprietary hardware would only include the latter without including the former.

History

openhardware.org logo (2013)
OSHWA logo

The first hardware-focused "open source" activities were started around 1997 by Bruce Perens, creator of the Open Source Definition, co-founder of the Open Source Initiative, and a ham radio operator. He launched the Open Hardware Certification Program, which had the goal of allowing hardware manufacturers to self-certify their products as open.

Shortly after the launch of the Open Hardware Certification Program, David Freeman announced the Open Hardware Specification Project (OHSpec), another attempt at licensing hardware components whose interfaces are available publicly and of creating an entirely new computing platform as an alternative to proprietary computing systems. In early 1999, Sepehr Kiani, Ryan Vallance and Samir Nayfeh joined efforts to apply the open-source philosophy to machine design applications. Together they established the Open Design Foundation (ODF) as a non-profit corporation and set out to develop an Open Design Definition. However, most of these activities faded out after a few years.

A "Free Hardware" organization, known as FreeIO, was started in the late 1990s by Diehl Martin, who also launched a FreeIO website in early 2000. In the early to mid 2000s, FreeIO was a focus of free/open hardware designs released under the GNU General Public License. The FreeIO project advocated the concept of Free Hardware and proposed four freedoms that such hardware provided to users, based on the similar freedoms provided by free software licenses. The designs gained some notoriety due to Martin's naming scheme in which each free hardware project was given the name of a breakfast food such as Donut, Flapjack, Toast, etc. Martin's projects attracted a variety of hardware and software developers as well as other volunteers. Development of new open hardware designs at FreeIO ended in 2007 when Martin died of pancreatic cancer but the existing designs remain available from the organization's website.

By the mid 2000s open-source hardware again became a hub of activity due to the emergence of several major open-source hardware projects and companies, such as OpenCores, RepRap (3D printing), Arduino, Adafruit, SparkFun, and Open Source Ecology. In 2007, Perens reactivated the openhardware.org website, but it's currently (August 2023) inactive.

Following the Open Graphics Project, an effort to design, implement, and manufacture a free and open 3D graphics chip set and reference graphics card, Timothy Miller suggested the creation of an organization to safeguard the interests of the Open Graphics Project community. Thus, Patrick McNamara founded the Open Hardware Foundation (OHF) in 2007.

The Tucson Amateur Packet Radio Corporation (TAPR), founded in 1982 as a non-profit organization of amateur radio operators with the goals of supporting R&D efforts in the area of amateur digital communications, created in 2007 the first open hardware license, the TAPR Open Hardware License. The OSI president Eric S. Raymond expressed some concerns about certain aspects of the OHL and decided to not review the license.

Around 2010 in context of the Freedom Defined project, the Open Hardware Definition was created as collaborative work of many and is accepted as of 2016 by dozens of organizations and companies.

In July 2011, CERN (European Organization for Nuclear Research) released an open-source hardware license, CERN OHL. Javier Serrano, an engineer at CERN's Beams Department and the founder of the Open Hardware Repository, explained: "By sharing designs openly, CERN expects to improve the quality of designs through peer review and to guarantee their users – including commercial companies – the freedom to study, modify and manufacture them, leading to better hardware and less duplication of efforts". While initially drafted to address CERN-specific concerns, such as tracing the impact of the organization's research, in its current form it can be used by anyone developing open-source hardware.

Following the 2011 Open Hardware Summit, and after heated debates on licenses and what constitutes open-source hardware, Bruce Perens abandoned the OSHW Definition and the concerted efforts of those involved with it. Openhardware.org, led by Bruce Perens, promotes and identifies practices that meet all the combined requirements of the Open Source Hardware Definition, the Open Source Definition, and the Four Freedoms of the Free Software Foundation Since 2014 openhardware.org is not online and seems to have ceased activity.

The Open Source Hardware Association (OSHWA) at oshwa.org acts as hub of open-source hardware activity of all genres, while cooperating with other entities such as TAPR, CERN, and OSI. The OSHWA was established as an organization in June 2012 in Delaware and filed for tax exemption status in July 2013. After some debates about trademark interferences with the OSI, in 2012 the OSHWA and the OSI signed a co-existence agreement.

The Free Software Foundation has suggested an alternative "free hardware" definition derived from the Four Freedoms.

Forms of open-source hardware

The term hardware in open-source hardware has been historically used in opposition to the term software of open-source software. That is, to refer to the electronic hardware on which the software runs (see previous section). However, as more and more non-electronic hardware products are made open source (for example WikiHouse, OpenBeam or Hovalin), this term tends to be used back in its broader sense of "physical product". The field of open-source hardware has been shown to go beyond electronic hardware and to cover a larger range of product categories such as machine tools, vehicles and medical equipment. In that sense, hardware refers to any form of tangible product, be it electronic hardware, mechanical hardware, textile or even construction hardware. The Open Source Hardware (OSHW) Definition 1.0 defines hardware as "tangible artifacts — machines, devices, or other physical things".

Electronics

Electronics is one of the most popular types of open-source hardware. There are many companies that provide large varieties of open-source electronics such as Sparkfun, Adafruit, and Seeed. In addition, there are NPOs and companies that provide a specific open-source electronic component such as the Arduino electronics prototyping platform. There are many examples of specialty open-source electronics such as low-cost voltage and current GMAW open-source 3-D printer monitor and a robotics-assisted mass spectrometry assay platform. Open-source electronics finds various uses, including automation of chemical procedures.

Mecha(tro)nics

A large range of open-source mechatronic products have been developed, including mechanical components, machine tools, vehicles, musical instruments, and medical equipment.

Examples of open-source machine tools include 3D printers such as RepRap, Prusa, and Ultimaker, 3D printer filament extruders such as polystruder XR PRO as well as the laser cutter Lasersaur. Open-source vehicles have also been developed including bicycles like XYZ Space Frame Vehicles and cars such as the Tabby OSVehicle. Examples of open source medical equipment include open-source ventilators, the echostethoscope echOpen, and a wide range of prosthetic hands listed in the review study by Ten Kate et.al. (e.g. OpenBionics' Prosthetic Hands).

Chip design

OSH chip designs are now common. RISC-V is an open instruction set architecture which has several OSH implementations. LowRISC is working on a complete OSH system on chip.

Other

Examples of open-source hardware products can also be found to a lesser extent in construction (Wikihouse), textile (Kit Zéro Kilomètres), and firearms (3D printed firearm, Defense Distributed).

Licenses

Rather than creating a new license, some open-source hardware projects use existing, free and open-source software licenses. These licenses may not accord well with patent law.

Later, several new licenses were proposed, designed to address issues specific to hardware design. In these licenses, many of the fundamental principles expressed in open-source software (OSS) licenses have been "ported" to their counterpart hardware projects. New hardware licenses are often explained as the "hardware equivalent" of a well-known OSS license, such as the GPL, LGPL, or BSD license.

Despite superficial similarities to software licenses, most hardware licenses are fundamentally different: by nature, they typically rely more heavily on patent law than on copyright law, as many hardware designs are not copyrightable. Whereas a copyright license may control the distribution of the source code or design documents, a patent license may control the use and manufacturing of the physical device built from the design documents. This distinction is explicitly mentioned in the preamble of the TAPR Open Hardware License:

"... those who benefit from an OHL design may not bring lawsuits claiming that design infringes their patents or other intellectual property."

— TAPR Open Hardware License

Noteworthy licenses include:

The Open Source Hardware Association recommends seven licenses which follow their open-source hardware definition. From the general copyleft licenses the GNU General Public License (GPL) and Creative Commons Attribution-ShareAlike license, from the hardware-specific copyleft licenses the CERN Open Hardware License (OHL) and TAPR Open Hardware License (OHL) and from the permissive licenses the FreeBSD license, the MIT license, and the Creative Commons Attribution license. Openhardware.org recommended in 2012 the TAPR Open Hardware License, Creative Commons BY-SA 3.0 and GPL 3.0 license.

Organizations tend to rally around a shared license. For example, OpenCores prefers the LGPL or a Modified BSD License, FreeCores insists on the GPL, Open Hardware Foundation promotes "copyleft or other permissive licenses", the Open Graphics Project uses a variety of licenses, including the MIT license, GPL, and a proprietary license, and the Balloon Project wrote their own license.

Development

The OSHW (Open Source Hardware) logo silkscreened on an unpopulated PCB

The adjective "open-source" not only refers to a specific set of freedoms applying to a product, but also generally presupposes that the product is the object or the result of a "process that relies on the contributions of geographically dispersed developers via the Internet." In practice however, in both fields of open-source hardware and open-source software, products may either be the result of a development process performed by a closed team in a private setting or by a community in a public environment, the first case being more frequent than the second which is more challenging. Establishing a community-based product development process faces several challenges such as: to find appropriate product data management tools, document not only the product but also the development process itself, accepting losing ubiquitous control over the project, ensure continuity in a context of fickle participation of voluntary project members, among others.

The Arduino Diecimila, another popular and early open source hardware design

One of the major differences between developing open-source software and developing open-source hardware is that hardware results in tangible outputs, which cost money to prototype and manufacture. As a result, the phrase "free as in speech, not as in beer", more-formally known as gratis versus libre, distinguishes between the idea of zero cost and the freedom to use and modify information. While open-source hardware faces challenges in minimizing cost and reducing financial risks for individual project developers, some community members have proposed models to address these needs Given this, there are initiatives to develop sustainable community funding mechanisms, such as the Open Source Hardware Central Bank.

Extensive discussion has taken place on ways to make open-source hardware as accessible as open-source software. Providing clear and detailed product documentation is an essential factor facilitating product replication and collaboration in hardware development projects. Practical guides have been developed to help practitioners to do so. Another option is to design products so they are easy to replicate, as exemplified in the concept of open-source appropriate technology.

The process of developing open-source hardware in a community-based setting is alternatively called open design, open source development or open source product development. All these terms are examples of the open-source model applicable for the development of any product, including software, hardware, cultural and educational. Does open design and open-source hardware design process involves new design practices, or raises requirements for new tools? is the question of openness really key in OSH?. See here for a delineation of these terms.

A major contributor to the production of open-source hardware product designs is the scientific community. There has been considerable work to produce open-source hardware for scientific hardware using a combination of open-source electronics and 3-D printing. Other sources of open-source hardware production are vendors of chips and other electronic components sponsoring contests with the provision that the participants and winners must share their designs. Circuit Cellar magazine organizes some of these contests.

Open-source labs

A guide has been published (Open-Source Lab (book) by Joshua Pearce) on using open-source electronics and 3D printing to make open-source labs. Today, scientists are creating many such labs. Examples include:

Business models

Open hardware companies are experimenting with business models. For example, littleBits implements open-source business models by making available the circuit designs in each electronics module, in accordance with the CERN Open Hardware License Version 1.2. Another example is Arduino, which registered its name as a trademark; others may manufacture products from Arduino designs but cannot call the products Arduino products. There are many applicable business models for implementing some open-source hardware even in traditional firms. For example, to accelerate development and technical innovation, the photovoltaic industry has experimented with partnerships, franchises, secondary supplier and completely open-source models.

Recently, many open-source hardware projects have been funded via crowdfunding on platforms such as Indiegogo, Kickstarter, or Crowd Supply.

Reception and impact

Richard Stallman, the founder of the free software movement, was in 1999 skeptical on the idea and relevance of free hardware (his terminology for what is now known as open-source hardware). In a 2015 article in Wired Magazine, he modified this attitude; he acknowledged the importance of free hardware, but still saw no ethical parallel with free software. Also, Stallman prefers the term free hardware design over open source hardware, a request which is consistent with his earlier rejection of the term open source software (see also Alternative terms for free software).ther authors, such as Professor Joshua Pearce have argued there is an ethical imperative for open-source hardware – specifically with respect to open-source appropriate technology for sustainable development. In 2014, he also wrote the book Open-Source Lab: How to Build Your Own Hardware and Reduce Research Costs, which details the development of free and open-source hardware primarily for scientists and university faculty. Pearce in partnership with Elsevier introduced a scientific journal HardwareX. It has featured many examples of applications of open-source hardware for scientific purposes.

Further, Vasilis Kostakis [et] et al have argued that open-source hardware may promote values of equity, diversity and sustainability. Open-source hardware initiative transcend traditional dichotomies of global-local, urban-rural, and developed-developing contexts. They may leverage cultural differences, environmental conditions, and local needs/resources, while embracing hyper-connectivity, to foster sustainability and collaboration rather than conflict. However, open-source hardware does face some challenges and contradictions. It must navigate tensions between inclusiveness, standardization, and functionality. Additionally, while open-source hardware may reduce pressure on natural resources and local populations, it still relies on energy- and material-intensive infrastructures, such as the Internet. Despite these complexities, Kostakis et al argue, the open-source hardware framework can serve as a catalyst for connecting and unifying diverse local initiatives under radical narratives, thus inspiring genuine change.

OSH has grown as an academic field through the two journals Journal of Open Hardware (JOH) and HardwareX. These journals compete to publish the best OSH designs, and each define their own requirements for what constitutes acceptable quality of design documents, including specific requirements for build instructions, bill of materials, CAD files, and licences. These requirements are often used by other OSH projects to define how to do an OSH release. These journals also publish papers contributing to the debate about how OSH should be defined and used.

Basic research

From Wikipedia, the free encyclopedia

Basic research, also called pure research, fundamental research, basic science, or pure science, is a type of scientific research with the aim of improving scientific theories for better understanding and prediction of natural or other phenomena. In contrast, applied research uses scientific theories to develop technology or techniques, which can be used to intervene and alter natural or other phenomena. Though often driven simply by curiosity, basic research often fuels the technological innovations of applied science. The two aims are often practiced simultaneously in coordinated research and development.

In addition to innovations, basic research also serves to provide insight into nature around us and allows us to respect its innate value. The development of this respect is what drives conservation efforts. Through learning about the environment, conservation efforts can be strengthened using research as a basis. Technological innovations can unintentionally be created through this as well, as seen with examples such as kingfishers' beaks affecting the design for high speed bullet trains in Japan.

Overview

Despite smart people working on this problem for 50 years, we're still discovering surprisingly basic things about the earliest history of our world. It's quite humbling. — Matija Ćuk, scientist at the SETI Institute and lead researcher, November 2016

Basic research advances fundamental knowledge about the world. It focuses on creating and refuting or supporting theories that explain observed phenomena. Pure research is the source of most new scientific ideas and ways of thinking about the world. It can be exploratory, descriptive, or explanatory; however, explanatory research is the most common.

Basic research generates new ideas, principles, and theories, which may not be immediately utilized but nonetheless form the basis of progress and development in different fields. Today's computers, for example, could not exist without research in pure mathematics conducted over a century ago, for which there was no known practical application at the time. Basic research rarely helps practitioners directly with their everyday concerns; nevertheless, it stimulates new ways of thinking that have the potential to revolutionize and dramatically improve how practitioners deal with a problem in the future.

History

By country

In the United States, basic research is funded mainly by federal government and done mainly at universities and institutes. As government funding has diminished in the 2010s, however, private funding is increasingly important.

Basic versus applied science

Applied science focuses on the development of technology and techniques. In contrast, basic science develops scientific knowledge and predictions, principally in natural sciences but also in other empirical sciences, which are used as the scientific foundation for applied science. Basic science develops and establishes information to predict phenomena and perhaps to understand nature, whereas applied science uses portions of basic science to develop interventions via technology or technique to alter events or outcomes Applied and basic sciences can interface closely in research and development. The interface between basic research and applied research has been studied by the National Science Foundation.

A worker in basic scientific research is motivated by a driving curiosity about the unknown. When his explorations yield new knowledge, he experiences the satisfaction of those who first attain the summit of a mountain or the upper reaches of a river flowing through unmapped territory. Discovery of truth and understanding of nature are his objectives. His professional standing among his fellows depends upon the originality and soundness of his work. Creativeness in science is of a cloth with that of the poet or painter.

It conducted a study in which it traced the relationship between basic scientific research efforts and the development of major innovations, such as oral contraceptives and videotape recorders. This study found that basic research played a key role in the development in all of the innovations. The number of basic science research that assisted in the production of a given innovation peaked between 20 and 30 years before the innovation itself. While most innovation takes the form of applied science and most innovation occurs in the private sector, basic research is a necessary precursor to almost all applied science and associated instances of innovation. Roughly 76% of basic research is conducted by universities.

A distinction can be made between basic science and disciplines such as medicine and technology. They can be grouped as STM (science, technology, and medicine; not to be confused with STEM [science, technology, engineering, and mathematics]) or STS (science, technology, and society). These groups are interrelated and influence each other, although they may differ in the specifics such as methods and standards.

The Nobel Prize mixes basic with applied sciences for its award in Physiology or Medicine. In contrast, the Royal Society of London awards distinguish natural science from applied science.

Wednesday, May 22, 2024

Open-design movement

From Wikipedia, the free encyclopedia
RepRap general-purpose 3D printer that not only could be used to make structures and functional components for open-design projects but is an open-source project itself
Uzebox is an open-design video game console.
Bug Labs open source hardware
Zoybar open source guitar kit with 3-D printed body

The open-design movement involves the development of physical products, machines and systems through use of publicly shared design information. This includes the making of both free and open-source software (FOSS) as well as open-source hardware. The process is generally facilitated by the Internet and often performed without monetary compensation. The goals and philosophy of the movement are identical to that of the open-source movement, but are implemented for the development of physical products rather than software. Open design is a form of co-creation, where the final product is designed by the users, rather than an external stakeholder such as a private company.

Origin

Sharing of manufacturing information can be traced back to the 18th and 19th century. Aggressive patenting put an end to that period of extensive knowledge sharing. More recently, principles of open design have been related to the free and open-source software movements. In 1997 Eric S. Raymond, Tim O'Reilly and Larry Augustin established "open source" as an alternative expression to "free software", and in 1997 Bruce Perens published The Open Source Definition. In late 1998, Dr. Sepehr Kiani (a PhD in mechanical engineering from MIT) realized that designers could benefit from open source policies, and in early 1999 he convinced Dr. Ryan Vallance and Dr. Samir Nayfeh of the potential benefits of open design in machine design applications. Together they established the Open Design Foundation (ODF) as a non-profit corporation, and set out to develop an Open Design Definition.

The idea of open design was taken up, either simultaneously or subsequently, by several other groups and individuals. The principles of open design are closely similar to those of open-source hardware design, which emerged in March 1998 when Reinoud Lamberts of the Delft University of Technology proposed on his "Open Design Circuits" website the creation of a hardware design community in the spirit of free software.

Ronen Kadushin coined the title "Open Design" in his 2004 Master's thesis, and the term was later formalized in the 2010 Open Design Manifesto.

Current directions

Open Source Ecology, open source farming and industrial machinery

The open-design movement currently unites two trends. On one hand, people apply their skills and time on projects for the common good, perhaps where funding or commercial interest is lacking, for developing countries or to help spread ecological or cheaper technologies. On the other hand, open design may provide a framework for developing advanced projects and technologies that might be beyond the resource of any single company or country and involve people who, without the copyleft mechanism, might not collaborate otherwise. There is now also a third trend, where these two methods come together to use high-tech open-source (e.g. 3D printing) but customized local solutions for sustainable development. Open Design holds great potential in driving future innovation as recent research has proven that stakeholder users working together produce more innovative designs than designers consulting users through more traditional means. The open-design movement may arguably organize production by prioritising socio-ecological well-being over corporate profits, over-production and excess consumption.

Open machine design as compared to open-source software

The open-design movement is currently fairly nascent but holds great potential for the future. In some respects design and engineering are even more suited to open collaborative development than the increasingly common open-source software projects, because with 3D models and photographs the concept can often be understood visually. It is not even necessary that the project members speak the same languages to usefully collaborate.

However, there are certain barriers to overcome for open design when compared to software development where there are mature and widely used tools available and the duplication and distribution of code cost next to nothing. Creating, testing and modifying physical designs is not quite so straightforward because of the effort, time and cost required to create the physical artefact; although with access to emerging flexible computer-controlled manufacturing techniques the complexity and effort of construction can be significantly reduced (see tools mentioned in the fab lab article).

Organizations

VIA OpenBook reference design CAD visualisation

Open design was considered in 2012 a fledgling movement consisting of several unrelated or loosely related initiatives. Many of these organizations are single, funded projects, while a few organizations are focusing on an area needing development. In some cases (e.g. Thingiverse for 3D printable designs or Appropedia for open source appropriate technology) organizations are making an effort to create a centralized open source design repository as this enables innovation. Notable organizations include:

Software rot

From Wikipedia, the free encyclopedia

Software rot (bit rot, code rot, software erosion, software decay, or software entropy) is the deterioration of software quality or performance over time that leads to it becoming faulty, unusable, or needing upgrade.

Since software cannot physically decay, the term is hyperbole. The process is due to either changes in the source code or to the environment in which the software operates.

The Jargon File, a compendium of hacker lore, defines "bit rot" as a jocular explanation for the degradation of a software program over time even if "nothing has changed"; the idea behind this is almost as if the bits that make up the program were subject to radioactive decay.

Causes

Several factors are responsible for software rot, including changes to the environment in which the software operates, degradation of compatibility between parts of the software itself, and the emergence of bugs in unused or rarely used code.

Environment change

When changes occur in the program's environment, particularly changes which the designer of the program did not anticipate, the software may no longer operate as originally intended. For example, many early computer game designers used the CPU clock speed as a timer in their games. However, newer CPU clocks were faster, so the gameplay speed increased accordingly, making the games less usable over time.

Onceability

There are changes in the environment not related to the program's designer, but its users. Initially, a user could bring the system into working order, and have it working flawlessly for a certain amount of time. But, when the system stops working correctly, or the users want to access the configuration controls, they cannot repeat that initial step because of the different context and the unavailable information (password lost, missing instructions, or simply a hard-to-manage user interface that was first configured by trial and error). Information Architect Jonas Söderström has named this concept Onceability, and defines it as "the quality in a technical system that prevents a user from restoring the system, once it has failed".

Unused code

Infrequently used portions of code, such as document filters or interfaces designed to be used by other programs, may contain bugs that go unnoticed. With changes in user requirements and other external factors, this code may be executed later, thereby exposing the bugs and making the software appear less functional.

Rarely updated code

Normal maintenance of software and systems may also cause software rot. In particular, when a program contains multiple parts which function at arm's length from one another, failing to consider how changes to one part that affect the others may introduce bugs.

In some cases, this may take the form of libraries that the software uses being changed in a way which adversely affects the software. If the old version of a library that previously worked with the software can no longer be used due to conflicts with other software or security flaws that were found in the old version, there may no longer be a viable version of a needed library for the program to use.

Online connectivity

Modern commercial software often connects to an online server for license verification and accessing information. If the online service powering the software is shut down, it may stop working.

Since the late 2010s most websites use secure HTTPS connections. However this requires encryption keys called root certificates which have expiration dates. After the certificates expire the device loses connectivity to most websites unless the keys are continuously updated.

Another issue is that in March 2021 old encryption standards TLS 1.0 and TLS 1.1 were deprecated. This means that operating systems, browsers and other online software that do not support at least TLS 1.2 cannot connect to most websites, even to download patches or update the browser, if these are available. This is occasionally called the "TLS apocalypse".

Products that cannot connect to most websites include PowerMacs, old Unix boxes and Microsoft Windows versions older than Server 2008/Windows 7. The Internet Explorer 8 browser in Server 2008/Windows 7 does support TLS 1.2 but it is disabled by default.

Classification

Software rot is usually classified as being either 'dormant rot' or 'active rot'.

Dormant rot

Software that is not currently being used gradually becomes unusable as the remainder of the application changes. Changes in user requirements and the software environment also contribute to the deterioration.

Active rot

Software that is being continuously modified may lose its integrity over time if proper mitigating processes are not consistently applied. However, much software requires continuous changes to meet new requirements and correct bugs, and re-engineering software each time a change is made is rarely practical. This creates what is essentially an evolution process for the program, causing it to depart from the original engineered design. As a consequence of this and a changing environment, assumptions made by the original designers may be invalidated, thereby introducing bugs.

In practice, adding new features may be prioritized over updating documentation; without documentation, however, it is possible for specific knowledge pertaining to parts of the program to be lost. To some extent, this can be mitigated by following best current practices for coding conventions.

Active software rot slows once an application is near the end of its commercial life and further development ceases. Users often learn to work around any remaining software bugs, and the behaviour of the software becomes consistent as nothing is changing.

Examples

AI program example

Many seminal programs from the early days of AI research have suffered from irreparable software rot. For example, the original SHRDLU program (an early natural language understanding program) cannot be run on any modern day computer or computer simulator, as it was developed during the days when LISP and PLANNER were still in development stage, and thus uses non-standard macros and software libraries which do not exist anymore.

Forked online forum example

Suppose an administrator creates a forum using open source forum software, and then heavily modifies it by adding new features and options. This process requires extensive modifications to existing code and deviation from the original functionality of that software.

From here, there are several ways software rot can affect the system:

  • The administrator can accidentally make changes which conflict with each other or the original software, causing the forum to behave unexpectedly or break down altogether. This leaves them in a very bad position: as they have deviated so greatly from the original code, technical support and assistance in reviving the forum will be difficult to obtain.
  • A security hole may be discovered in the original forum source code, requiring a security patch. However, because the administrator has modified the code so extensively, the patch may not be directly applicable to their code, requiring the administrator to effectively rewrite the update.
  • The administrator who made the modifications could vacate their position, leaving the new administrator with a convoluted and heavily modified forum that lacks full documentation. Without fully understanding the modifications, it is difficult for the new administrator to make changes without introducing conflicts and bugs. Furthermore, documentation of the original system may no longer be available, or worse yet, misleading due to subtle differences in functional requirements.

Wiki example

Suppose a webmaster installs the latest version of MediaWiki, the software that powers wikis such as Wikipedia, then never applies any updates. Over time, the web host is likely to update their versions of the programming language (such as PHP) and the database (such as MariaDB) without consulting the webmaster. After a long enough time, this will eventually break complex websites that have not been updated, because the latest versions of PHP and MariaDB will have breaking changes as they hard deprecate certain built-in functions, breaking backwards compatibility and causing fatal errors. Other problems that can arise with un-updated website software include security vulnerabilities and spam.

Refactoring

Refactoring is a means of addressing the problem of software rot. It is described as the process of rewriting existing code to improve its structure without affecting its external behaviour. This includes removing dead code and rewriting sections that have been modified extensively and no longer work efficiently. Care must be taken not to change the software's external behaviour, as this could introduce incompatibilities and thereby itself contribute to software rot. Some design principles to consider when it comes to refactoring is maintaining the hierarchical structure of the code and implementing abstraction to simplify and generalize code structures.

Operator (computer programming)

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