Humorism, or humoralism, was a system of medicine detailing the makeup and workings of the human body, adopted by Ancient Greek and Roman physicians and philosophers.
Origin
The concept of "humors" (i.e. chemical systems regulating human
behaviour) became more prominent from the writing of medical theorist Alcmaeon of Croton (C. 540–500BC). His list of humours was longer than just four liquids and included fundamental elements described by Empedocles, such as water, air, earth, etc. Some authors suggest that the concept of "humours" may have origins in Ancient Egyptian medicine or Mesopotamia, though it was not systemized until ancient Greek thinkers.
The word humor is a translation of Greek χυμός, chymos (literally juice or sap, metaphorically flavor). However much earlier than this, ancient Indian Ayurveda medicine had developed a theory of three humors, which they linked with the five Hindu elements.
Hippocrates is the one usually credited with applying this idea to medicine. In contrast to Alcmaeon, Hippocrates
suggested that humours are the vital bodily fluids, such as blood,
yellow bile, phlegm and "black bile" (he probably referred to blood
composites in patients with bleeding internal organs). Alcmaeon and Hippocrates posited that an extreme excess or deficiency of any of the humours bodily fluid
in a person can be a sign of illness. Hippocrates and then Galen
suggested that a moderate imbalance in the mixture of these fluids
produces temperament (behavioural) type. One of the treatises attributed to Hippocrates, On the Nature of Man, describes the theory as follows:
The Human body contains blood, phlegm, yellow bile and black bile. These are the things that make up its constitution and cause its pains and health. Health is primarily that state in which these constituent substances are in the correct proportion to each other, both in strength and quantity, and are well mixed. Pain occurs when one of the substances presents either a deficiency or an excess, or is separated in the body and not mixed with others.
Although the theory of the four humors does appear in some
Hippocratic texts, some Hippocratic writers only accepted the existence
of two humors, while some even refrained from discussing the humoral
theory at all.
Humoralism, or the doctrine of the four temperaments, as a medical
theory retained its popularity for centuries largely through the
influence of the writings of Galen
(129–201 AD). Hippocrates theory of four humours was linked with the
popular theory of the four elements: earth, fire, water and air proposed
by Empedocles but this link wasn't proposed by Hippocrates or Galen
who referred primarily to bodily fluids. While Galen thought that
humors were formed in the body, rather than ingested, he believed that
different foods had varying potential to be acted upon by the body to
produce different humors. Warm foods, for example, tended to produce
yellow bile, while cold foods tended to produce phlegm. Seasons of the
year, periods of life, geographic regions and occupations also
influenced the nature of the humors formed.
The four temperaments as depicted in an 18th-century woodcut: phlegmatic, choleric, sanguine and melancholic.
The imbalance of humors, or dyscrasia, was thought to be the direct cause of all diseases. Health was associated with a balance of humors, or eucrasia.
The qualities of the humors, in turn, influenced the nature of the
diseases they caused. Yellow bile caused warm diseases and phlegm caused
cold diseases. In On the Temperaments, Galen further emphasized
the importance of the qualities. An ideal temperament involved a
balanced mixture of the four qualities. Galen identified four
temperaments in which one of the qualities, warm, cold, moist or dry,
predominated and four more in which a combination of two, warm and
moist, warm and dry, cold and dry or cold and moist, dominated. These
last four, named for the humors with which they were associated—that is,
sanguine, choleric, melancholic and phlegmatic, eventually became
better known than the others. While the term temperament came to refer just to psychological
dispositions, Galen used it to refer to bodily dispositions, which
determined a person's susceptibility to particular diseases as well as
behavioral and emotional inclinations.
Disease could also be the result of the "corruption" of one or
more of the humors, which could be caused by environmental
circumstances, dietary changes, or many other factors.
These deficits were thought to be caused by vapors inhaled or absorbed
by the body. Greeks and Romans, and the later Muslim and Western
European medical establishments that adopted and adapted classical
medical philosophy, believed that each of these humors would wax and
wane in the body, depending on diet and activity. When a patient was
suffering from a surplus or imbalance of one of these four fluids, then
said patient's personality and or physical health could be negatively
affected.
Four humors
Even
though humorism theory had several models that used 2, 3 and 5
components, the most famous model consists of the four humors described
by Hippocrates and then developed further by Galen. The four humors of Hippocratic medicine are black bile (Greek: μέλαινα χολή, melaina chole), yellow bile (Greek: ξανθη χολή, xanthe chole), phlegm (Greek: φλέγμα, phlegma), and blood (Greek: αἷμα, haima). Each corresponds to one of the traditional four temperaments.
Based on Hippocratic medicine, it was believed that the four humors
were to be in balanced proportions with regard to amount and strength of
each humor for a body to be healthy. The proper blending and balance of the four humors was known as ‘eukrasia’. Imbalance and separation of humors leads to diseases.
Galen recalls the correspondence between humors and seasons in his On the Doctrines of Hippocrates and Plato,
and says that, "As for ages and the seasons, the child (παῖς)
corresponds to spring, the young man (νεανίσκος) to summer, the mature
man (παρακµάζων) to autumn, and the old man (γέρων) to winter".
Galen also believed that the characteristics of the soul follow the
mixtures of the body but he does not apply this idea to the hippocratic
humours. He believed that the phlegm did not influence character. Here
is what he says in his On Hippocrates’ The Nature of Man:
“Sharpness and intelligence (ὀξὺ καὶ συνετόν) are caused by yellow bile
in the soul, perseverance and consistency (ἑδραῖον καὶ βέβαιον) by the
melancholic humour, and simplicity and naivety (ἁπλοῦν καὶ ἠλιθιώτερον)
by blood. But the nature of phlegm has no effect on the character of the
soul (τοῦ δὲ φλέγµατος ἡ φύσις εἰς µὲν ἠθοποιῗαν ἄχρηστος).” He further said that blood is a mixture of four elements: water, air, fire, earth.
These terms only partly correspond to the modern medical terminology, in which there is no distinction between black and yellow bile and phlegm
has a very different meaning. It was believed that these were the basic
substances from which all liquids in the body were made. Robin Fåhræus
(1921), a Swedish physician who devised the erythrocyte sedimentation rate,
suggested that the four humours were based upon the observation of
blood clotting in a transparent container. When blood is drawn in a
glass container and left undisturbed for about an hour, four different
layers can be seen. A dark clot forms at the bottom (the "black bile").
Above the clot is a layer of red blood cells (the "blood"). Above this
is a whitish layer of white blood cells (the "phlegm"). The top layer is
clear yellow serum (the "yellow bile").
Many Greek texts were written during the golden age of the theory of the four humors in Greek medicine after Galen. One of those texts was an anonymous treatise called On the Constitution of the Universe and of Man,
published in the mid-nineteenth century by J.L. Ideler. In this text
the author establishes the relationship between elements of the universe
(air, water, earth, fire) and elements of the man (blood, yellow bile, black bile, phlegm). He said that:
- The people who have red blood are friendly, they joke and laugh around about their bodies and for their appearance they are rose tinted, slightly red, and have pretty skin.
- The people who have yellow bile are bitter, short tempered, daring. They appear greenish and have yellow skin.
- The people who are composed of black bile are lazy, fearful, and sickly. They have black hair and black eyes.
- Those who have phlegm are low spirited, forgetful, and have white hair.
Blood
The blood was believed to be produced exclusively by the liver. It was associated with a sanguine nature (enthusiastic, active, and social).
Yellow bile
Excess
of yellow bile was thought to produce aggression, and reciprocally
excess anger to cause liver derangement and imbalances in the humors.
Black bile
The word "melancholy" derives from Greek μέλαινα χολή (melaina kholé) meaning 'black bile'. Depression was attributed to excess or unnatural black bile secreted by the spleen.
Phlegm
Phlegm was thought to be associated with apathetic behavior, as preserved in the word "phlegmatic". The phlegm of humorism is far from the same thing as phlegm as it is defined today. The French physiologist and Nobel laureate Charles Richet,
when describing humorism's "phlegm or pituitary secretion" in 1910,
asked rhetorically, "this strange liquid, which is the cause of tumours,
of chlorosis, of rheumatism, and cacochymia—where is it? Who will ever
see it? Who has ever seen it? What can we say of this fanciful
classification of humours into four groups, of which two are absolutely
imaginary?"
Humor Production
Humors are produced via digestion and are the final products of hepatic digestion. Digestion is a continuous process taking place in every human being and it can be divided into four sequential stages. The gastric digestion stage, the hepatic digestion stage, the vascular digestion stage, and the tissue digestion
stage. Each stage digests food until it becomes suitable for use by the
body. In gastric digestion, food is made into chylous which is suitable
for liver
to absorb and carry on digestion. Chylous is changed into ‘chymous’ in
the hepatic digestion stage. Chymous is composed of the four humors:
blood, phlegm, yellow bile, and black bile. These four humors then
circulate in the vessels. And in the last stage of digestion, tissue digestion, food becomes similar to the organ tissue that it is destined for.
If anything goes wrong leading up to the formation of humors, the
humors will not be in good condition. From the kind of food that goes
into the body to the proper organ functioning is necessary in the
production of good humor. The stomach
and liver have to function normally in order for proper digestion. If
there are any abnormalities in gastric digestion the liver, blood
vessels and tissues can not be provided with the raw chylous and that
can cause abnormal humor and blood composition. A healthy functioning
liver is not even capable of converting abnormal chylous into normal
chylous and then normal humors.
Humors are the end product of gastric digestion but they are not
the end product of the digestion cycle so an abnormal humor produced by
hepatic digestion will lead to affect other organs that are working
towards the digestion of the food in the digestion cycle.
Unification of humorism with Empedocles model
Empedocles's theory suggested that there are four elements:
earth, fire, water, and air; with earth producing the natural systems.
Since this theory was influential for centuries, later scholars paired
qualities associated with each humour as described by Hippocrates-Galen
with seasons and "basic elements" as described by Empedocles.
The following table shows the four humors with their
corresponding elements, seasons, sites of formation, and resulting
temperaments:
| Humour | Season | Ages | Element | Organ | Qualities | Temperament |
| Blood | spring | infancy | air | liver | warm and moist | sanguine |
| Yellow bile | summer | youth | fire | gallbladder | warm and dry | choleric |
| Black bile | autumn | adulthood | earth | spleen | cold and dry | melancholic |
| Phlegm | winter | old age | water | brain/lungs | cold and moist | phlegmatic |
Influence and legacy
Islamic medicine
Medieval medical tradition in the "Golden Age of Islam" adopted the theory of humorism from Greco-Roman medicine, notably via the Persian polymath Avicenna's The Canon of Medicine (1025). Avicenna summarized the four humors and temperaments as follows:
| Evidence | Hot | Cold | Moist | Dry |
|---|---|---|---|---|
| Morbid states | Inflammations become febrile | Fevers related to serious humor, rheumatism | Lassitude | Loss of vigour |
| Functional power | Deficient energy | Deficient digestive power | Difficult digestion |
|
| Subjective sensations | Bitter taste, excessive thirst, burning at cardia | Lack of desire for fluids | Mucoid salivation, sleepiness | Insomnia, wakefulness |
| Physical signs | High pulse rate, lassitude | Flaccid joints | Diarrhea, swollen eyelids, rough skin, acquired habit | rough skin, acquired habit |
| Foods and medicines | Calefacients harmful, infrigidants[25] beneficial | Infrigidants harmful, calefacients beneficial | Moist articles harmful | Dry regimen harmful, humectants beneficial |
| Relation to weather | Worse in summer | Worse in winter |
|
Bad in autumn |
Perso-Arabic and Indian medicine
The Unani school of medicine, practiced in Perso-Arabic countries, India, and Pakistan, is based on Galenic and Avicennian medicine in its emphasis on the four humors as a fundamental part of the methodologic paradigm.
Western Medicine
The
humoralist system of medicine was highly individualistic, for all
patients were said to have their own unique humoral composition. From Hippocrates onward, the humoral theory was adopted by Greek, Roman and Islamic physicians, and dominated the view of the human body among European physicians until at least 1543 when it was first seriously challenged by Andreas Vesalius.
Vesalius mostly criticized Galen's theories of human anatomy and not
the chemical hypothesis of behavioural regulation (temperament).
However, some believe that theory of humours was cast into the underside
of science in 1628 by the findings of William Harvey (also criticising mostly anatomy theory of Galen) and by Rudolf Virchow's theories of cellular pathology in 1858.
The four humors and their qualities
Typically "eighteenth-century" practices such as bleeding
a sick person or applying hot cups to a person were, in fact, based on
the humoral theory of imbalances of fluids (blood and bile in those
cases). Ben Jonson wrote humor plays, where types were based on their humoral complexion.
Methods of treatment like bloodletting, emetics
and purges were aimed at expelling a surfeit of a humor. Other methods
used herbs and foods associated with a particular humor to counter
symptoms of disease, for instance: people who had a fever and were
sweating were considered hot and wet and therefore given substances
associated with cold and dry. Paracelsus
further developed the idea that beneficial medical substances could be
found in herbs, minerals and various alchemical combinations thereof.
These beliefs were the foundation of mainstream Western medicine well
into the 17th century.
Central to the treatment of unbalanced humors was the use of
herbs. Specific herbs were used to treat all ailments simple, common
and complex etc., from an uncomplicated upper respiratory infection to
the plague. For example, chamomile was used to decrease heat, and lower
excessive bile humor. Also, arsenic was used in a poultice bag to
'draw out' the excess humor(s) that led to symptoms of the plague.
Philip Moore, who wrote on the hope of health, and Edwards, who wrote Treatise concerning the Plague
discuss how these herbs are helpful in curing physical disease. They
also discuss the importance of maintaining an herb garden. Apophlegmatisms, in pre-modern medicine, were medications chewed in order to draw away phlegm and humours.
Although advances in cellular pathology and chemistry criticized
humoralism by the seventeenth century, the theory had dominated Western
medical thinking for more than 2,000 years.
Only in some instances did the theory of humoralism wane into
obscurity. One such instance occurred in the sixth and seventh centuries
in the Byzantine Empire when traditional secular Greek culture gave way
to Christian influences. Though the use of humoralist medicine
continued during this time, its influence was diminished in favor of
religion.
The revival of Greek humoralism, owing in part to changing social and
economic factors, did not begin until the early ninth century. Use of the practice in modern times is pseudoscience.
Modern use
There
are still remnants of the theory of the four humors in the current
medical language. For example, modern medicine refers to humoral immunity or humoral regulation when describing substances such as hormones and antibodies that circulate throughout the body. It also uses the term blood dyscrasia to refer to any blood disease or abnormality.
The concept of humorism was not "definitively demolished" until 1858.
There were no studies performed to prove or disprove the impact of
dysfunction in known bodily organs producing named fluids (humors) on temperament traits simply because the list of temperament traits were not defined up until the end of 20th century.
Culture
Theophrastus
and others developed a set of characters based on the humors. Those
with too much blood were sanguine. Those with too much phlegm were
phlegmatic. Those with too much yellow bile were choleric, and those
with too much black bile were melancholic. The idea of human
personality based on humors contributed to the character comedies of Menander and, later, Plautus.
Through the neo-classical revival in Europe, the humor theory dominated
medical practice, and the theory of humoral types made periodic
appearances in drama.
The humors can be found in Elizabethan works, such as in Taming of the Shrew,
in which the character Petruchio pretends to be irritable and angry to
show Katherina what it is like being around a disagreeable person. He
yells at the servants for serving mutton, a "choleric" food, to two
people who are already choleric.
Foods in Elizabethan times were all believed to have an affinity
with one of these four humors. A person showing signs of phlegmatism
might have been served wine (a choleric drink and the direct opposite
humor to phlegmatic) to balance this.
