Search This Blog

Saturday, June 6, 2026

Behavioral neuroscience

From Wikipedia, the free encyclopedia
https://en.wikipedia.org/wiki/Behavioral_neuroscience

Behavioral neuroscience, also known as biological psychologybiopsychology, or psychobiology, is part of the broad, interdisciplinary field of neuroscience, with its primary focus being on the biological and neural substrates underlying human experiences and behaviors, as in our psychology. Derived from an earlier field known as physiological psychology, behavioral neuroscience applies the principles of biology to study the physiological, genetic, and developmental mechanisms of behavior in humans and other animals.

Behavioral neuroscientists examine the biological bases of behavior through research that involves neuroanatomical substrates, environmental and genetic factors, effects of lesions and electrical stimulation, developmental processes, recording electrical activity, neurotransmitters, hormonal influences, chemical components, and the effects of drugs. Important topics of consideration for neuroscientific research in behavior include learning and memory, sensory processes, motivation and emotion, as well as genetic and molecular substrates concerning the biological bases of behavior. Subdivisions of behavioral neuroscience include the field of cognitive neuroscience, which emphasizes the biological processes underlying human cognition. Behavioral and cognitive neuroscience are both concerned with the neuronal and biological bases of psychology, with a particular emphasis on either cognition or behavior depending on the field.

History

Behavioral neuroscience as a scientific discipline emerged from a variety of scientific and philosophical traditions in the 18th and 19th centuries. René Descartes proposed physical models to explain animal as well as human behavior. Descartes suggested that the pineal gland, a midline unpaired structure in the brain of many organisms, was the point of contact between mind and body. Descartes also elaborated on a theory in which the pneumatics of bodily fluids could explain reflexes and other motor behavior. This theory was inspired by moving statues in a garden in Paris.

Other philosophers also helped give birth to psychology. One of the earliest textbooks in the new field, The Principles of Psychology by William James, argues that the scientific study of psychology should be grounded in an understanding of biology.

1907 image of a brain

The emergence of psychology and behavioral neuroscience as legitimate sciences can be traced from the emergence of physiology from anatomy, particularly neuroanatomy. Physiologists conducted experiments on living organisms, a practice that was distrusted by the dominant anatomists of the 18th and 19th centuries. The influential work of Claude Bernard, Charles Bell, and William Harvey helped to convince the scientific community that reliable data could be obtained from living subjects.

Even before the 18th and 19th centuries, behavioral neuroscience was beginning to take form as far back as 1700 B.C. The question that seems to continually arise is: what is the connection between the mind and body? The debate is formally referred to as the mind-body problem. There are two major schools of thought that attempt to resolve the mind–body problem; monism and dualismPlato and Aristotle are two of several philosophers who participated in this debate. Plato believed that the brain was where all mental thought and processes happened. In contrast, Aristotle believed the brain served the purpose of cooling down the emotions derived from the heart. The mind-body problem was a stepping stone toward attempting to understand the connection between the mind and body.

William James

Another debate arose about localization of function or functional specialization versus equipotentiality which played a significant role in the development in behavioral neuroscience. As a result of localization of function research, many famous people found within psychology have come to various different conclusions. Wilder Penfield was able to develop a map of the cerebral cortex through studying epileptic patients along with Rassmussen. Research on localization of function has led behavioral neuroscientists to a better understanding of which parts of the brain control behavior. This is best exemplified through the case study of Phineas Gage.

The term "psychobiology" has been used in a variety of contexts, emphasizing the importance of biology, which is the discipline that studies organic, neural and cellular modifications in behavior, plasticity in neuroscience, and biological diseases in all aspects, in addition, biology focuses and analyzes behavior and all the subjects it is concerned about, from a scientific point of view. In this context, psychology helps as a complementary, but important discipline in the neurobiological sciences. The role of psychology in this questions is that of a social tool that backs up the main or strongest biological science. The term "psychobiology" was first used in its modern sense by Knight Dunlap in his book An Outline of Psychobiology (1914). Dunlap also was the founder and editor-in-chief of the journal Psychobiology. In the announcement of that journal, Dunlap writes that the journal will publish research "...bearing on the interconnection of mental and physiological functions", which describes the field of behavioral neuroscience even in its modern sense.

In relation to the discipline, Solomon Carter Fuller (1872 – 1953) also aided in the advancement of neurology and psychology with his Alzheimer's research. Dr. Fuller was the first African American psychiatrist and one of the pioneers of Alzheimer's disease. In 1904, Dr. Fuller began working as a research assistant under the founder of Alzheimer's disease, Alois Alzheimer, studying presenile dementia. Later in 1912, Dr. Fuller published the first review on Alzheimer's disease that included information regarding his patient who was the 9th person to ever be diagnosed with the disease. During his time as a researcher and doctor, he worked with black veterans to prevent them from getting misdiagnosed and deemed ineligible for military benefits; he also trained staff to diagnose side effects from sexually transmitted infections. In 1969, an award was established by the American Psychiatric Association called the Solomon Carter Fuller Award to honor black pioneers who worked to help other black people.

Neuroscience is considered a relatively new discipline, with the first conference for the Society of Neuroscience occurring in 1971. The meeting was held to merge different fields focused on studying the nervous system (ex. neuroanatomy, neurochemistry, physiological psychology, neuroendocrinology, clinical neurology, neurophysiology, neuropharmacology, etc.) by creating one interdisciplinary field. In 1983, the Journal of Comparative and Physiological Psychology, published by the American Psychological Association, was split into two separate journals: Behavioral Neuroscience and the Journal of Comparative Psychology. The author of the journal at the time gave reasoning for this separation, with one being that behavioral neuroscience is the broader contemporary advancement of physiological psychology. Furthermore, in all animals, the nervous system is the organ of behavior. Therefore, every biological and behavioral variable that influences behavior must go through the nervous system to do so. Present-day research in behavioral neuroscience studies all biological variables which act through the nervous system and relate to behavior.

Relationship to other fields of psychology and biology

In many cases, humans may serve as experimental subjects in behavioral neuroscience experiments; however, a great deal of the experimental literature in behavioral neuroscience comes from the study of non-human species, most frequently rats, mice, and monkeys. As a result, a critical assumption in behavioral neuroscience is that organisms share biological and behavioral similarities, enough to permit extrapolations across species. This allies behavioral neuroscience closely with comparative psychology, ethology, evolutionary biology, and neurobiology. Behavioral neuroscience also has paradigmatic and methodological similarities to neuropsychology, which relies heavily on the study of the behavior of humans with nervous system dysfunction (i.e., a non-experimentally based biological manipulation).

Research methods

The distinguishing characteristic of a behavioral neuroscience experiment is that either the independent variable of the experiment is biological, or some dependent variable is biological. In other words, the nervous system of the organism under study is permanently or temporarily altered, or some aspect of the nervous system is measured (usually to be related to a behavioral variable).

Disabling or decreasing neural function

  • Lesions – A classic method in which a brain-region of interest is naturally or intentionally destroyed to observe any resulting changes such as degraded or enhanced performance on some behavioral measure. Lesions can be placed with relatively high accuracy "Thanks to a variety of brain 'atlases' which provide a map of brain regions in 3-dimensional" stereotactic coordinates.
    The part of the picture emphasized shows the lesion in the brain. This type of lesion can be removed through surgery.
    • Surgical lesions – Neural tissue is destroyed by removing it surgically.
    • Electrolytic lesions – Neural tissue is destroyed through the application of electrical shock trauma.
    • Chemical lesions – Neural tissue is destroyed by the infusion of a neurotoxin.
    • Temporary lesions – Neural tissue is temporarily disabled by cooling or by the use of anesthetics such as tetrodotoxin.
  • Transcranial magnetic stimulation – A new technique usually used with human subjects in which a magnetic coil applied to the scalp causes unsystematic electrical activity in nearby cortical neurons which can be experimentally analyzed as a functional lesion.
  • Synthetic ligand injection – A receptor activated solely by a synthetic ligand (RASSL) or Designer Receptor Exclusively Activated by Designer Drugs (DREADD), permits spatial and temporal control of G protein signaling in vivo. These systems utilize G protein-coupled receptors (GPCR) engineered to respond exclusively to synthetic small molecules ligands, like clozapine N-oxide (CNO), and not to their natural ligand(s). RASSL's represent a GPCR-based chemogenetic tool. These synthetic ligands upon activation can decrease neural function by G-protein activation. This can with Potassium attenuating neural activity.
  • Optogenetic inhibition – A light activated inhibitory protein is expressed in cells of interest. Powerful millisecond timescale neuronal inhibition is instigated upon stimulation by the appropriate frequency of light delivered via fiber optics or implanted LEDs in the case of vertebrates, or via external illumination for small, sufficiently translucent invertebrates. Bacterial Halorhodopsins or Proton pumps are the two classes of proteins used for inhibitory optogenetics, achieving inhibition by increasing cytoplasmic levels of halides (Cl
    ) or decreasing the cytoplasmic concentration of protons, respectively.

Enhancing neural function

  • Electrical stimulation – A classic method in which neural activity is enhanced by application of a small electric current (too small to cause significant cell death).
  • Psychopharmacological manipulations – A chemical receptor antagonist induces neural activity by interfering with neurotransmission. Antagonists can be delivered systemically (such as by intravenous injection) or locally (intracerebrally) during a surgical procedure into the ventricles or into specific brain structures. For example, NMDA antagonist AP5 has been shown to inhibit the initiation of long term potentiation of excitatory synaptic transmission (in rodent fear conditioning) which is believed to be a vital mechanism in learning and memory.
  • Synthetic Ligand Injection – Likewise, Gq-DREADDs can be used to modulate cellular function by innervation of brain regions such as Hippocampus. This innervation results in the amplification of γ-rhythms, which increases motor activity.
  • Transcranial magnetic stimulation – In some cases (for example, studies of motor cortex), this technique can be analyzed as having a stimulatory effect (rather than as a functional lesion).
  • Optogenetic excitation – A light activated excitatory protein is expressed in select cells. Channelrhodopsin-2 (ChR2), a light activated cation channel, was the first bacterial opsin shown to excite neurons in response to light, though a number of new excitatory optogenetic tools have now been generated by improving and imparting novel properties to ChR2.

Measuring neural activity

  • Optical techniques – Optical methods for recording neuronal activity rely on methods that modify the optical properties of neurons in response to the cellular events associated with action potentials or neurotransmitter release.
    • Voltage sensitive dyes (VSDs) were among the earliest method for optically detecting neuronal activity. VSDs commonly changed their fluorescent properties in response to a voltage change across the neuron's membrane, rendering membrane sub-threshold and supra-threshold (action potentials) electrical activity detectable. Genetically encoded voltage sensitive fluorescent proteins have also been developed.
    • Calcium imaging relies on dyes or genetically encoded proteins that fluoresce upon binding to the calcium that is transiently present during an action potential.
    • Synapto-pHluorin is a technique that relies on a fusion protein that combines a synaptic vesicle membrane protein and a pH sensitive fluorescent protein. Upon synaptic vesicle release, the chimeric protein is exposed to the higher pH of the synaptic cleft, causing a measurable change in fluorescence.
  • Single-unit recording – A method whereby an electrode is introduced into the brain of a living animal to detect electrical activity that is generated by the neurons adjacent to the electrode tip. Normally this is performed with sedated animals but sometimes it is performed on awake animals engaged in a behavioral event, such as a thirsty rat whisking a particular sandpaper grade previously paired with water in order to measure the corresponding patterns of neuronal firing at the decision point.
  • Multielectrode recording – The use of a bundle of fine electrodes to record the simultaneous activity of up to hundreds of neurons.
  • Functional magnetic resonance imaging – fMRI, a technique most frequently applied on human subjects, in which changes in cerebral blood flow can be detected in an MRI apparatus and are taken to indicate relative activity of larger scale brain regions (i.e., on the order of hundreds of thousands of neurons).
  • PET brain scans can show chemical differences in the brain between addicts and non-addicts. The normal images in the bottom row come from non-addicts while people with addictions have scans that look more abnormal.
    Positron emission tomography - PET detects particles called photons using a 3-D nuclear medicine examination. These particles are emitted by injections of radioisotopes such as fluorine. PET imaging reveal the pathological processes which predict anatomic changes making it important for detecting, diagnosing and characterising many pathologies.
  • Electroencephalography – EEG, and the derivative technique of event-related potentials, in which scalp electrodes monitor the average activity of neurons in the cortex (again, used most frequently with human subjects). This technique uses different types of electrodes for recording systems such as needle electrodes and saline-based electrodes. EEG allows for the investigation of mental disorders, sleep disorders and physiology. It can monitor brain development and cognitive engagement.
  • Electrocorticography – ECoG, similar to an EGG, the ECoG records the brains electrical activity and is commonly used on patients to monitor and evaluate epilepsy or seizures. However, the ECoG is an invasive medical procedure that measures signals directly from the brains surface. The ECoG provides high spatial and temporal resolution as opposed to its non-invasive counterpart, the EEG which has low temporal and spatial resolution. Due to the invasiveness of the procedure, the data for human patients is harder to collect than a standard EEG assessment.
  • Functional neuroanatomy – A more complex counterpart of phrenology. The expression of some anatomical marker is taken to reflect neural activity. For example, the expression of immediate early genes is thought to be caused by vigorous neural activity. Likewise, the injection of 2-deoxyglucose prior to some behavioral task can be followed by anatomical localization of that chemical; it is taken up by neurons that are electrically active.
  • Magnetoencephalography – MEG shows the functioning of the human brain through the measurement of electromagnetic activity. Measuring the magnetic fields created by the electric current flowing within the neurons identifies brain activity associated with various human functions in real time, with millimeter spatial accuracy. Clinicians can noninvasively obtain data to help them assess neurological disorders and plan surgical treatments.

Genetic techniques

  • QTL mapping – The influence of a gene in some behavior can be statistically inferred by studying inbred strains of some species, most commonly mice. The recent sequencing of the genome of many species, most notably mice, has facilitated this technique.
  • Selective breeding – Organisms, often mice, may be bred selectively among inbred strains to create a recombinant congenic strain. This might be done to isolate an experimentally interesting stretch of DNA derived from one strain on the background genome of another strain to allow stronger inferences about the role of that stretch of DNA.
  • Genetic engineering – The genome may also be experimentally-manipulated; for example, knockout mice can be engineered to lack a particular gene, or a gene may be expressed in a strain which does not normally do so (the 'transgenic'). Advanced techniques may also permit the expression or suppression of a gene to occur by injection of some regulating chemical.

Quantifying behavior

  • Fruit fly (Drosophila melanogaster) leg joints being tracked in 3D with Anipose.
    Markerless pose estimation – The advancement of computer vision techniques in recent years have allowed for precise quantifications of animal movements without needing to fit physical markers onto the subject. On high-speed video captured in a behavioral assay, keypoints from the subject can be extracted frame-by-frame, which is often useful to analyze in tandem with neural recordings/manipulations. Analyses can be conducted on how keypoints (i.e. parts of the animal) move within different phases of a particular behavior (on a short timescale), or throughout an animal's behavioral repertoire (longer timescale). These keypoint changes can be compared with corresponding changes in neural activity. A machine learning approach can also be used to identify specific behaviors (e.g. forward walking, turning, grooming, courtship, etc.), and quantify the dynamics of transitions between behaviors.

Other research methods

Computational models - Using a computer to formulate real-world problems to develop solutions. Although this method is often focused in computer science, it has begun to move towards other areas of study. For example, psychology is one of these areas. Computational models allow researchers in psychology to enhance their understanding of the functions and developments in nervous systems. Examples of methods include the modelling of neurons, networks and brain systems and theoretical analysis. Computational methods have a wide variety of roles including clarifying experiments, hypothesis testing and generating new insights. These techniques play an increasing role in the advancement of biological psychology.

Limitations and advantages

Different manipulations have advantages and limitations. Neural tissue destroyed as a primary consequence of a surgery, electric shock or neurotoxin can confound the results so that the physical trauma masks changes in the fundamental neurophysiological processes of interest. For example, when using an electrolytic probe to create a purposeful lesion in a distinct region of the rat brain, surrounding tissue can be affected: so, a change in behavior exhibited by the experimental group post-surgery is to some degree a result of damage to surrounding neural tissue, rather than by a lesion of a distinct brain region. Most genetic manipulation techniques are also considered permanent. Temporary lesions can be achieved with advanced in genetic manipulations, for example, certain genes can now be switched on and off with diet. Pharmacological manipulations also allow blocking of certain neurotransmitters temporarily as the function returns to its previous state after the drug has been metabolized.

Topic areas

Experimental setup for noninvasive theta-burst stimulation of the human striatum to enhance striatal activity and motor skill learning.

In general, behavioral neuroscientists study various neuronal and biological processes underlying behavior, though limited by the need to use nonhuman animals. As a result, the bulk of literature in behavioral neuroscience deals with experiences and mental processes that are shared across different animal models such as:

However, with increasing technical sophistication and with the development of more precise noninvasive methods that can be applied to human subjects, behavioral neuroscientists are beginning to contribute to other classical topic areas of psychology, philosophy, and linguistics, such as:

Behavioral neuroscience has also had a strong history of contributing to the understanding of medical disorders, including those that fall under the purview of clinical psychology, clinical neuropsychology, and biological psychopathology (also known as abnormal psychology). Although animal models do not exist for all mental illnesses, the field has contributed important therapeutic data on a variety of conditions, including:

  • Parkinson's disease, a degenerative disorder of the central nervous system that often impairs motor skills and speech.
  • Huntington's disease, a rare inherited neurological disorder whose most obvious symptoms are abnormal body movements and a lack of coordination. It also affects a number of mental abilities and some aspects of personality.
  • Alzheimer's disease, a neurodegenerative disease that, in its most common form, is found in people over the age of 65 and is characterized by progressive cognitive deterioration, together with declining activities of daily living and by neuropsychiatric symptoms or behavioral changes.
  • Clinical depression, a common psychiatric disorder, characterized by a persistent lowering of mood, loss of interest in usual activities and diminished ability to experience pleasure.
  • Schizophrenia, a psychiatric diagnosis that describes a mental illness characterized by impairments in the perception or expression of reality, most commonly manifesting as auditory hallucinations, paranoid or bizarre delusions or disorganized speech and thinking in the context of significant social or occupational dysfunction.
  • Autism, a brain development disorder that impairs social interaction and communication, and causes restricted and repetitive behavior, all starting before a child is three years old. However, neuropsychologist, which are individuals in a behavioral neuroscience subfield have used mindfulness interventions to combat socially disruptive behaviors in autistic children.
  • Anxiety, a physiological state characterized by cognitive, somatic, emotional, and behavioral components. These components combine to create the feelings that are typically recognized as fear, apprehension, or worry.
  • Drug abuse, a chronic behavioral disorder in which individuals seek reward and pleasure reinforcement through uncontrollable drug use.
  • Alcoholism, a behavioral disorder in which individuals compulsively consume alcoholic substances. This disorder can result in several medical, neurological, and psychiatric conditions.

Research on topic areas

Cognition

High resolution fMRI of the human brain.

Behavioral neuroscientists conduct research on various cognitive processes through the use of different neuroimaging techniques. Examples of cognitive research might involve examination of neural correlates during emotional information processing, such as one study that analyzed the relationship between subjective affect and neural reactivity during sustained processing of positive (savoring) and negative (rumination) emotion. The aim of the study was to analyze whether repetitive positive thinking (seen as being beneficial) and repetitive negative thinking (significantly related to worse mental health) would have similar underlying neural mechanisms. Researchers found that the individuals who had a more intense positive affect during savoring, were also the same individuals who had a more intense negative affect during rumination. fMRI data showed similar activations in brain regions during both rumination and savoring, suggesting shared neural mechanisms between the two types of repetitive thinking. The results of the study suggest there are similarities, both subjectively and mechanistically, with repetitive thinking about positive and negative emotions. This overall suggests shared neural mechanisms by which sustained emotional processing of both positive and negative information occurs.

Stress

Research within the field of behavioral neuroscience involves looking at the complex neuroanatomy underlying different emotional processes, such as stress. Godoy et al. (2018) did so by providing an in-depth analyzation of the neurobiological underpinnings of the stress response. The article features on an overview on the historical development of stress research and its importance leading up to research related to both physical and psychological stressors today. The authors explored various significators of stress and their corresponding neuroanatomical processing, along with the temporal dynamics of both acute and chronic stress and its effects on the brain. Overall, the article provides a comprehensive scientific overview of stress through a neurobiological lens, highlighting the importance of our current knowledge in stress-related research areas today.

Sensation and Perception

Another common research topic within behavioral neuroscience is sensation and perception. Wu et al. (2023) conducted a study that analyzed auditory and somatosensory realms association with psychosocial factors (e.g., depression) and cognitive impairment among the geriatric population. The article discussed how hearing loss is the most common form of sensory dysfunction within the geriatric population as 2.5 billion people will experience this type of sensory depletion. The researchers used the Chinese version Mini-Mental State Examination (MMSE), Nottingham Sensory Assessment scale (NSA), Albert's test, Geriatric Depression Scale-30, and the Lubben Social network Scale-6 (LSNS-6) to assess cognitive function, sensation, perception, and negative socio-psychological factors (i.e., depression and social isolation), respectively. After performing a statistical analysis based on the participants assessment scores it was found that older people with auditorial sensory loss, atypical perception, and depression are more at risk for cognitive impairment. However, implications such as rehabilitation, non-pharmacological interventions for sensory loss and depression may reduce the amount of cognitive impairment older adults experience.

Awards

Nobel Laureates

The following Nobel Prize winners could reasonably be considered behavioral neuroscientists or neurobiologists. (This list omits winners who were almost exclusively neuroanatomists or neurophysiologists; i.e., those that did not measure behavioral or neurobiological variables.)

Kavli Prize in Neuroscience

Friday, June 5, 2026

Medical–industrial complex

Medical equipment and devices

The medical–industrial complex (MIC) refers to a network of interactions between pharmaceutical corporations, health care personnel, and medical conglomerates to supply health care-related products and services for a profit. The term is derived from the idea of the military–industrial complex.

Following the MIC's conception in 1970, the term has undergone an evolution by critical theory scholars throughout the early 21st century—including the fields of disability studies, Black studies, feminism, and queer studies—to describe forces of oppression against marginalized communities as they exist in the healthcare field. Prior to the conception of the "medical-industrial complex" term, themes related to the MIC were discussed in earlier American society, as shown through the work and philosophies of Rana A. Hogarth and Francis Galton.

The medical–industrial complex is often discussed in the context of conflict of interest in the health care industry and is often regarded as a result of modernized healthcare and capitalism. Discussions regarding the medical-industrial complex often concern the United States healthcare system, and propose that pharmaceutical and healthcare companies, including for-profit chain hospitals, may influence physicians' decisions through financial incentives. Physicians may also face constraints from corporate regulations and potential conflicts of interest related to investments in medical device companies. Although some large medical journals have been criticized for potentially biased publications, efforts have been made to maintain neutrality in medical literature. Continuing medical education programs funded by pharmaceutical companies may also influence physician preferences. Finally, patients may be affected by the MIC through the promotion of cosmetic surgery, drug price inflation, and physician bias. The Food and Drug Administration has implemented laws to protect patients against the potential negative impacts of the medical-industrial complex in the United States. These perspectives on the medical-industrial complex also apply to countries outside the United States, such as India and Brazil.

Drawing from diverse theoretical frameworks and the collective efforts of historically marginalized communities, critics have proposed alternatives to the medical-industrial complex that aim to reimagine health as a holistic concept, challenge the medicalization of sickness, and integrate lived experiences into healthcare settings.

Origin

In his 1961 farewell address, President Dwight D. Eisenhower commented on the influence and immensity of the military in American society: "...we must guard against the acquisition of unwarranted influence, whether sought or unsought, by the military-industrial complex." This new term, the military-industrial complex, depicts a sphere of influence between a national military and the defense industry which provides essential supplies to the military. Deriving from this, the compound term composed of the intended institution with "industrial complex" is created to describe the conflict of interest between an institution's supposed goal, and the desire to profit from the businesses/agencies that profit from serving the institution. The conceptual framework of the medical-industrial complex sits alongside the military-industrial complex and the prison-industrial complex, among others, to delineate the influence of free market capitalism in sociopolitical systems and institutions.

The concept of a "medical–industrial complex" was first advanced by Barbara and John Ehrenreich in the November 1969 issue of the Bulletin of the Health Policy Advisory Center in an article entitled "The Medical Industrial Complex" and in a subsequent book (with Health-PAC), The American Health Empire: Power, Profits, and Politics (Random House, 1970). In "The Medical Industrial Complex," the emergence of the American medical industrial complex is attributed to "the growing rapport between the delivery and products industry." This definition of the medical-industrial complex describes the history of the American healthcare system, specifically the creation of social programs Medicare and Medicaid, as an industry that has transformed into a central, essential role of the American national economy. References to the perpetuation of healthcare disparities by the medical-industrial complex are described, such as "class and cultural antagonisms." Differences in accessibility of healthcare between rural and urban populations are also made at this time.

In 1980, Dr. Arnold S. Relman published a further discussion of the medical-industrial complex in The New England Journal of Medicine when he was editor-in-chief, entitled "The New Medical-Industrial Complex." Relman notably explicitly excludes pharmaceutical companies and medical equipment companies in his description of the medical-industrial complex. Relman argues that "in a capitalistic society there are no practical alternatives to the private manufacture of drugs and medical equipment." Relman still identifies the novelty of the modern medical-industrial complex, describing the medical-industrial complex as an "unprecedented phenomenon with broad and potentially troubling implications." As with the Ehrenreich definition, the medical-industrial complex continues an emphasis on profit maximization on behalf of private corporations. The "cream-skimming" phenomenon is described, where proprietary hospitals can "skim the cream" off the market, by focusing on wealthy patients who can afford the most profitable procedures and services; nonprofit hospitals are therefore left with the remaining patient base.

In the 21st century, the medical industrial complex has come to encompass a system of oppression and subject of critical analysis by scholars, activists, organizers, and advocates. The Health Justice Commons describes the medical-industrial complex as intertwined institutions, including big pharma, as well as health insurance companies, medical technology companies, and governmental regulatory bodies. Per the Health Justice Commons, the medical-industrial complex reinforces "racism, sexism, classism, homophobia, transphobia and ableism." The nature and extent of the medical-industrial complex is a subject of debate by scholars, including those who specialize in fields of critical theory, such as disability studies, queer theory, and Black studies. According to encyclopedia.com, the Medical-Industrial Complex has "contributed to improvements in the health status of the population" but "it has also strengthened and preserved the private sector and protected a plurality of vested interests."

History

The existence of the medical-industrial complex as a concept is a product of the development of the modern American healthcare system. In the 19th century, the profession and practice of medicine underwent significant professionalization and growth. Experimentation on enslaved people was common. Doctors such as gynecologist J. Marion Sims operated on enslaved black women without anesthesia in order to document and develop gynecological medical issues and techniques to repair them. The creation of hospitals to treat the sick create further disparities in favor of urban, white populations.

The contemporary American healthcare system was shaped by the passage of the Hill-Burton Act, Medicare, Medicaid, and most recently, the Affordable Care Act. The latter social programs attempt to diminish the disparity of populations with difficulties maintaining health insurance, but does not attempt to reduce the private sector. The medical-industrial complex endeavors to reconcile the modern healthcare establishment with the long-term health inequalities.

Some elements of the medical-industrial complex, including the experimentation on marginalized populations, were introduced much prior to the modern American healthcare system. The conglomerate as it is now known is the synthesis of the modern healthcare system with developed capitalism.

1780–1840

In the historical monograph Medicalizing Blackness: Making Racial Differences in the Atlantic World, 1780-1840, Rana A. Hogarth discusses "the ways in which blackness was reified in medical discourses and used to perpetuate notions of white supremacy," and, consequently, harm and oppression. For example, Hogarth discusses how "white physicians constructed images of healthy and robust black bodies capable of enduring brutal labor regimes" while also identifying "deficiencies within these bodies that disqualified them for self-government." Importantly, Hogarth argues that oppression of black individuals using science predates the justification of slavery, and, instead has more to do with the origins of the medical industrial complex that allowed for the "intellectual, professional, and pecuniary gains" of physicians in the English-speaking greater Caribbean region over those of black individuals.

1900s–present

Francis Galton, in a black and white picture, seated on a chair in a suit

Eugenics has played a prominent role in the history of the MIC. The term eugenics was introduced in 1904, by Francis Galton. It was defined as "the science which deals with all influences that improve and develop the inborn qualities of a race" with the goal of "represent[ing] each class or sect by its best specimens, causing them to contribute more than their proportion to the next generation." Galton's concept of eugenics soon propagated ideas that certain groups of people, whether they were distinguished by race, ability, or socioeconomic status, were superior to others. Renowned journals, such as Nature, published work by Galton and other eugenicists, thereby making it easier for eugenics to become a legitimate field in science.

Some instances of eugenics are infamous in society, such as the justification of the mass ethnic genocide of Jewish people during the Holocaust by arguing that society was in need of racial purification.

Other examples of eugenics, such as the selective abortion of children with disabilities, are more controversial. Other notable eugenic-like practices include compulsory sterilization of black and poor individuals and scientific racism.

For more, see eugenics.

Within the United States

Healthcare corporations

Pharmaceutical companies and chain hospitals are key healthcare corporations within the Medical Industrial complex.

Influence of pharmaceutical companies

Packaged drugs ready for distribution

Pharmaceutical companies are a leading influence in the expansion of the Medical-Industrial Complex. Generic pharmaceutical drugs, which have the same chemical properties as branded, profitable drugs, are often sold for a fraction of the cost of their counterparts. For example, a 10 mg dose of asthma medication Singulair can cost up to $250 per month, whereas its generic counterpart Montelukast costs only ~$20 per month. Despite the inflated prices of brand-name drugs, pharmaceutical companies often induce bias in health care professionals by disproportionately promoting brand-name drugs. For example, research has shown that pharmaceutical companies promote branded drugs more, making physicians more likely to prescribe an expensive medicine over a generic alternative.

In addition to drugs, Laboratory Tests are also influenced by pharmaceutical company's vested interests. Physicians are more likely to order unnecessary tests when they are advertised by familiar pharmaceutical companies. Like branded drugs, many pharmaceutical companies set these tests at inflated prices to increase profit.

Influence of chain hospitals

Chain hospitals, in collaboration with pharmaceutical companies, also lead to the escalation of health costs. A chain hospital is a subsidiary of a hospital network that works under a for-profit goal of expanding healthcare and establishing hospitals across a country, most notably the United States. These corporations set standards regarding care administration, regulation, and enforcement – often without implementing a proper code of medical ethics. Chain hospitals and other healthcare conglomerates hold a monopoly over health care costs within their hospitals and respective subsidiaries. Thus, they can inflate healthcare costs with the goal of increasing profit, or lowering hospital standards to cut corners where necessary.

This cost inflation is exacerbated by the fact that health care organizations are increasingly managed by business staff who often focus on economic gain, rather than local medical practitioners whose focus is patient benefit. Moreover, hospitals in one state can be monitored by systems elsewhere, which gives significantly less power to local healthcare professionals.

Bias in education

The curriculum of medical students often incorporates readings from large medical journals, like the New England Journal of Medicine. These peer-reviewed journals may present results that favor expensive drugs manufactured by healthcare corporations or pharmaceutical companies, as these same corporations help to fund the journal. As such, these large journals can perpetuate bias in healthcare providers' medication preferences by presenting results that are inherently influenced by the motives of businesses.

Continuing medical education

Beyond medical school education, continuing medical education for healthcare is also subject to biased curriculum that disproportionately promotes the interest of its funders. To continue practicing as a board-certified physician, a physician must take continuing medical education courses. Such programs ensure that physicians are up-to-date with new medicines and treatment plans. However, these continuing education courses are often sponsored by pharmaceutical companies and healthcare corporations that can instill bias in physicians' education via the material provided. For example, if a course is sponsored by a medical device company, then the coursework and exams used often reference using the company's medical device. In turn, when the course is completed, it is more likely that physicians will use that medical device when interacting with patients regardless of if that medical device is necessary in the patients treatment.

There are entities that work to reduce bias in continuing medical education courses, including the Accreditation Council for Continuing Medical Education. Other groups, like the Medical education agency, work to reduce the influence of pharmaceutical companies and hospital corporations in the continuing medical education process.

Cosmetic rhinoplasty results

Consequences

The MIC poses unique difficulties for patients and physicians. For patients dealing with widespread diseases, treatment often comes with steep prices in Medicare and insurance. In recent 2020 health-care research, data has expressed how pandemics like COVID-19 have further tested the preparedness of the entire system's ability to combat a rapidly spreading virus.

Patient-level

A health professional offers a unique service to patients, since patients often defer to the guidance and wisdom of their healthcare provider. Many healthcare corporations are cognizant of the general population's lack of medical knowledge and possess the ability to set prices. This unequal relationship between healthcare corporations and the populace is especially important as it involves the complex interaction between making a profit from a patient's suffering, but also physicians having to treat the patient as effectively as possible. For patients who do not have access to reliable health insurance, this system imposes expensive medical treatment that they must pay for.

For patients with a chronic illness, diagnosis often means expensive medications for the rest of one's life. Chronic illnesses like depression may require medications until the disease is treated, whereas more severe chronic illnesses like cystic fibrosis require expensive medical and pharmaceutical treatments for one's entire life. These diseases could be treated, but their unique long-lasting nature means money can be generated from life-long treatments as opposed to a curative treatment.

Individuals in low-income households and racial minority groups have experienced most of the impact of the high prices in the medical-industrial complex during the pandemic. Over one third of Latino adults or low-income adults were uninsured at some point during 2020. In 2020, African Americans infected with COVID-19 died at a rate of 97.9 out of every 100,000, which is a death rate over twice as high as the death rates in white people (46.6/100,000) and Asians (40.4/100,000), and a third higher than Latinos (64.7/100,000). Notably, the death rate of African Americans is comparable to that of Indigenous populations (81.9/100,000).

Physician-level

Physicians are also subject to the medical-industrial complex and its manifestations. Throughout the 21st century, plastic surgery has become more common, a process where individuals undergo surgeries to resolve cosmetic issues. Cosmetic surgeries are often used to satisfy a certain beauty standardFor-profit healthcare promotes such non-essential healthcare services so that more profits can be created from healthy populations.

The phrase "no margin, no mission" is often used to describe for-profit healthcare, where medical centers adapt to corporate interests. For physicians, this can mean not treating uninsured patients, performing unnecessary procedures that generate profit, or supplying better care to patients when they have better means of pay. For-profit healthcare can have great moral and ethical considerations for physicians who feel obligated to care more for well-insured patients as opposed to under-insured, vulnerable patients.

Corporate entities, including insurance companies, also enforce standards surrounding medical treatment and payout. These rules disregard ethical and moral dilemmas that physicians often face, setting unattainable guidelines for certain situations. Physicians are often tied between healthcare corporations and insurance companies determining what they can and cannot do for a patient, regardless of if the treatment plan is necessary or not.

Manufacturers of medical devices also fund medical education programs, physicians, and hospitals to encourage the use of their devices. Many pharmaceutical and medical device companies are investor-based, meaning that if a device or drug receives FDA approval, investing physicians will be financially invested in the device's success or demise. Thus, a physician who is financially involved in a product or service is more likely to promote or use the product, whether or not its efficacy is known. This provides a conflict of interest for physicians, who may not provide their patients with effective, safe treatment due to bias for one product over another.

Laws and policies

As indicated in Mia Mingus' diagram above, the "Medical Industrial Complex" is intertwined with the effects of economic policy on the practice of medicine. The Dalkon Shield is an interesting example of the conflict between economic profit and patient well being:

Over a decade since the invention of the Dalkon Shield, the Safe Medical Devices Act of 1990 was passed by the FDA as an amendment to the FDCA. This act required medical device manufacturer to report any information about medical devices that could contribute to death, sickness, or injury. As such, healthcare professionals were required to report malfunctioning or unsafe medical equipment.

Additionally, the Physician Payments Sunshine Act, created by the United States Department of Justice, declared that all contracts that medical device companies make with physicians must be made public. As such, this act could prevent future physicians from promoting or overusing medical devices on patients to further personal interests over patient benefit.

In other countries

Indian Medical Association Clinic

The healthcare system in the United States performs worse on health indicators compared to other major nations, despite the country's higher investment in healthcare. This is reflected in lower ratings for life expectancy and satisfaction among U.S. citizens. Some argue that these lower ratings are partly due to the fact that the United States does not provide universal health coverage, unlike many other nations. Some major differences between the United States and other major countries include quality, access, efficiency, equity, and life expectancy.

White savior-industrial complex

Countries in the Global South do not always have the same amount and quality of resources as countries in the Global North. Due to these disparities, scholars argue that the white savior industrial complex (WSIC) has influenced healthcare systems on individual, interpersonal, structural, and global levels. Coined by Teju Cole, the WSIC refers to the phenomenon where privileged white individuals seek personal fulfillment by trying to "liberate, rescue, or otherwise uplift underprivileged people of color." According to this concept, people with a white savior mentality may believe they know what is best for other countries, although such individuals often end up causing more harm than good. One such example describes how a white American physician caused Ugandan medical staff to doubt their knowledge and ability in delivering a baby. Another example recounts how a White male physician used his privilege to influence medical staff in India to subvert their traditional medical practices. Scholars cite these anecdotes as examples of how widespread the WSIC has become.

India

Some individuals claim that the medical-industrial complex also exists in India, where the Indian Medical Association lobbies for their interests in local and state politics. Specifically, some doctors have accused the Indian Medical Association of engaging in unethical practices and obstructing the advancement of healthcare systems within the medical profession. The Indian Medical Association has responded to these claims by stating that their critics exaggerate rare occasions of unethical practices. Yet, some doctors have privately admitted to immoral actions and have stated that these practices are not limited to a few individual patients. Ethics is a contentious topic both within and beyond the medical profession. Claims of unethical practices may stem from the stark contrast between healthcare systems ranging from tall, high-tech hospitals to dilapidated, dirty ones. Some medical professionals and scholars suggest that stricter office guidelines may decrease unethical practices, but this could also raise the cost of healthcare for patients.

Brazil

In Brazil, scholars refer to the medical-industrial complex as the "healthcare-industrial complex." The healthcare-industrial complex also expands beyond Brazil, where internal infrastructure fails to meet medical demands, leaving patients unable to access necessary products and services. Scholars argue that Brazil's medical history reflects poor distribution of social and economic medical policies, resulting in underdeveloped and underfunded healthcare sectors in poor communities. The Program for Investment in the Health Industrial Complex, or PROCIS, funds medical research in Brazil to advance the country's global presence in pharmaceutical and medical industries. According to the Brazilian Ministry of Health, PROCIS was formed with the goal of developing Brazil's internal healthcare structure and promoting research, development, and treatment. Over 100 billion Brazilian reals have been devoted to supporting medical research efforts, development of the medical industry, and innovating existing medical products. The PROCIS also established a margin of preference on healthcare products that are nationally funded and sourced.

Cultural criticisms

A group of scholars and activists offer critiques and alternative approaches to the medical-industrial complex.

Alternative approaches

Alternative approaches to the medical-industrial complex incorporate elements from different theoretical frameworks and practices, such as holism, environmentalism, reproductive justice, the disability rights movement, feminism, and other related concepts. These alternative approaches stem from the collective efforts of historically marginalized activists facing structural violence, including Indigenous, Black, and migrant communities. According to various scholars, these alternative approaches aim to reimagine health as a holistic concept that extends beyond the traditional focus of the medical-industrial complex to include the body, mind, and spirit. Furthermore, these alternative approaches challenge the medicalization of illness and disease by highlighting how structural factors shape health, rather than just individual behaviors. Alternative approaches to the medical-industrial complex also challenge the boundaries between patient and provider to encourage collaboration between the two and to center the lived experiences of individuals in the healing process. Additionally, they highlight the importance of forming caring relationships within one's community to establish a sense of solidarity among individuals as equal participants in the healing process.

One alternative approach to the MIC is presented by disability activist, Eli Clare, who describes the Medical-Industrial Complex in a negative light, stating that, through the MIC "all of our body-minds are judged in one way or another, found to be normal or abnormal, valuable or disposable, healthy or unhealthy." He argues that the MIC is a critical component of the ideology of cure by shaping "our understandings of health and well- being, disability and disease" and perpetuating the idea that bodies and minds need improving. Clare describes the MIC as being pervasive throughout our lived experiences, "sustained by the labor of many people, ranging from doctors to nursing home administrators, nursing aides to psychiatrists, physical therapists to researchers, scientists to marketing directors." Moreover, he states that the MIC is perpetuated by pharmaceutical companies, medical ad agencies, laboratories and all health facilities. Simultaneously, Clare acknowledges that cure, and thus the medical industrial complex, has helped many individuals to cope with chronic diseases or illnesses that have caused them pain. Throughout his novel, Brilliant Imperfection: Battling with Cure, Clare suggests that we, as a society, must work to re-imagine a world with a more nuanced and critical view of cure and the MIC.

Another alternative approach to the MIC is mindfulness, which emphasizes how the resources and tools for healing exist within the self and not within the solutions offered by the medical-industrial complex. Another distinct approach from the medical-industrial complex is alternative health, which incorporates elements of traditional medicine and focuses on addressing underlying factors of disease rather than merely treating symptoms. Alternative health, as a new social movement, provides a space for individuals and communities with diverse lived experiences to actively participate in the healthcare system while emphasizing their humanity in the healing process. Scholars Jonathan Metzl and Helena Hansen advocate for a new approach to medical education in the United States, termed structural competency, which entails clinicians' ability to comprehend and address social determinants of health during patient interactions.

Dialectic

From Wikipedia, the free encyclopedia

Dialectic (Ancient Greek: διαλεκτική, romanizeddialektikḗ; German: Dialektik), also known as the dialectical method, refers originally to dialogue between people holding different points of view about a subject but wishing to arrive at the truth through reasoned argument. Dialectic resembles debate, but the concept excludes subjective elements such as emotional appeal and rhetoric; the object is more an eventual and commonly held truth than the "winning" of an (often binary) competition. It has its origins in ancient philosophy and continued to be developed in the Middle Ages.

Hegelianism refigured "dialectic" to no longer refer to a literal dialogue. Instead, the term takes on the specialized meaning of development by way of overcoming internal contradictions. Dialectical materialism, a theory advanced by Karl Marx and Friedrich Engels, adapted the Hegelian dialectic into a materialist theory of history. The legacy of Hegelian and Marxian dialectics has been criticized by philosophers, such as Karl Popper and Mario Bunge, who considered it unscientific.

Dialectic implies a developmental process and so does not fit naturally within classical logic. Nevertheless, some twentieth-century logicians have attempted to formalize it.

Classical philosophy

In classical philosophy, dialectic (Ancient Greek: διαλεκτική dialektikḗ) is a form of reasoning based upon dialogue of arguments and counter-arguments, advocating propositions (theses) and counter-propositions (antitheses). The outcome of such a dialectic might be the refutation of a relevant proposition, or a combination of the opposing assertions (a synthesis), or a qualitative improvement of the dialogue. Socrates has become famous for his Socratic method of questioning conversation partners on topics until they agreed with him or admitted ignorance.

Platonism

In Platonism, dialectic assumed an ontological and metaphysical role in that it became the process whereby the intellect passes from sensibles to intelligibles, rising from idea to idea until it finally grasps the supreme idea, the first principle, which is the origin of all. The philosopher is consequently a "dialectician". In this sense, dialectic is a process of inquiry that does away with hypotheses up to the first principle. It slowly embraces multiplicity in unity. The philosopher Simon Blackburn wrote that the dialectic in this sense is used to understand "the total process of enlightenment, whereby the philosopher is educated so as to achieve knowledge of the supreme good, the Form of the Good".

Aristotle

Aristotle has been traditionally understood as viewing dialectic as a lesser method of reasoning than demonstration, which derives a necessarily true conclusion, from premises assumed to be true, via syllogism. Within the Organon, the series comprising Aristotle's works about logic, the Topics is dedicated to dialectic—which he characterizes as argument from endoxa ("generally accredited opinions") where positions are subject to lines of questioning, to which concessions may be made in response. While Aristotle asserts "dialectic does not prove anything", he considers it to be a useful art closely related to rhetoric.

Medieval philosophy

In the medieval period, dialectic was a foundational element of the trivium (grammar, rhetoric, and logic/dialectic), the essential curriculum in arts faculties at early universities. Drawing heavily on the works of Aristotle, as transmitted and commented upon by figures like Boethius, medieval thinkers employed dialectic as a rigorous method for analyzing texts and pursuing truth through reasoned argumentation. This practice was most notably formalized in the academic exercise known as the quaestio disputata (disputed question), a structured public debate where scholars presented arguments for and against a specific proposition drawn from authoritative sources such as Scripture, Church Fathers, or classical philosophers. The goal was not merely to win a debate but to use logical analysis to resolve apparent contradictions between different authorities, reconcile faith with reason, and arrive at a unified, deeper understanding of the subject matter. This method of systematic inquiry and rigorous logical consistency formed the bedrock of Scholasticism and the Western intellectual tradition, laying the groundwork for later developments in modern philosophy and science.

Following Boethius (480–524), who drew heavily on Aristotle, many scholastic philosophers made use of dialectics in their works, including Peter AbelardWilliam of SherwoodGarlandus CompotistaWalter Burley, Roger Swyneshed, William of Ockham, and Thomas Aquinas.

This dialectic (a quaestio disputata) was formed as follows:

  1. The question to be determined ("It is asked whether...");
  2. A provisional answer to the question ("And it seems that...");
  3. The principal arguments in favor of the provisional answer;
  4. An argument against the provisional answer, traditionally a single argument from authority ("On the contrary...");
  5. The determination of the question after weighing the evidence ("I answer that...");
  6. The replies to each of the initial objections. ("To the first, to the second etc., I answer that...")

Modern philosophy

The concept of dialectics was given new life at the start of the nineteenth century by Georg Wilhelm Friedrich Hegel, whose dialectical model of nature and of history made dialectics a fundamental aspect of reality, instead of regarding the contradictions into which dialectics leads as evidence of the limits of pure reason, as Immanuel Kant had argued. Hegel was influenced by Johann Gottlieb Fichte's conception of synthesis, although Hegel didn't adopt Fichte's thesis–antithesis–synthesis language except to describe Kant's philosophy: rather, Hegel argued that such language was "a lifeless schema" imposed on various contents, whereas he saw his own dialectic as flowing out of "the inner life and self-movement" of the content itself.

In the mid-nineteenth century, Hegelian dialectic was appropriated by Karl Marx and Friedrich Engels and retooled in what they considered to be a nonidealistic manner. It would also become a crucial part of later representations of Marxism as a philosophy of dialectical materialism. These representations often contrasted dramatically and led to vigorous debate among different Marxist groups.

Hegelian dialectic

The Hegelian dialectic describes changes in the forms of thought, through their own internal contradictions, into concrete forms that overcome previous oppositions.

This dialectic is sometimes presented in a threefold manner, as first stated by Heinrich Moritz Chalybäus, as comprising three dialectical stages of development: a thesis, giving rise to its reaction; an antithesis, which contradicts or negates the thesis; and the tension between the two being resolved by means of a synthesis. However, Hegel opposed these terms.

By contrast, the terms abstract, negative, and concrete suggest a flaw or an incompleteness in any initial thesis. For Hegel, the concrete must always pass through the phase of the negative, that is, mediation. This is the essence of what is popularly called Hegelian dialectics.

To describe the activity of overcoming the negative, Hegel often used the term Aufheben, variously translated into English as 'sublation' or 'overcoming', to conceive of the working of the dialectic. Roughly, the term indicates preserving the true portion of an idea, thing, society, and so forth, while moving beyond its limitations. What is sublated, on the one hand, is overcome, but, on the other hand, is preserved and maintained.

As in the Socratic dialectic, Hegel claimed to proceed by making implicit contradictions explicit: each stage of the process is the product of contradictions inherent or implicit in the preceding stage. In his view, the purpose of dialectics is "to study things in their own being and movement and thus to demonstrate the finitude of the partial categories of understanding".

For Hegel, even history can be reconstructed as a unified dialectic, the major stages of which chart a progression from self-alienation as servitude to self-unification and realization as the rational constitutional state of free and equal citizens.

Marxist dialectic

Marxist dialectic is a form of Hegelian dialectic which applies to the study of historical materialism. Marxist dialectic is thus a method by which one can examine social and economic behaviors. It is the foundation of the philosophy of dialectical materialism, which forms the basis of historical materialism.

In the Marxist tradition, "dialectic" refers to regular and mutual relationships, interactions, and processes in nature, society, and human thought.

A dialectical relationship is a relationship in which two phenomena or ideas mutually impact each other, leading to development and negation. Development refers to the change and motion of phenomena and ideas from less advanced to more advanced or from less complete to more complete. Dialectical negation refers to a stage of development in which a contradiction between two previous subjects gives rise to a new subject. In the Marxist view, dialectical negation is never an endpoint, but instead creates new conditions for further development and negation.

Karl Marx and Friedrich Engels, writing several decades after Hegel's death, proposed that Hegel's dialectic is too abstract. Against this, Marx presented his own dialectic method, which he claimed to be "direct opposite" of Hegel's method.

Marxist dialectics is exemplified in Das Kapital. As Marx explained,

it includes in its comprehension an affirmative recognition of the existing state of things, at the same time, also, the recognition of the negation of that state, of its inevitable breaking up; because it regards every historically developed social form as in fluid movement, and therefore takes into account its transient nature not less than its momentary existence; because it lets nothing impose upon it, and is in its essence critical and revolutionary.

Class struggle is the primary contradiction to be resolved by Marxist dialectics because of its central role in the social and political lives of a society. Marx believed the struggle between the capitalist class (the purchasers of labor-power) and the working class (the sellers of labor-power) to be the primary contradiction of the capitalist mode of production, and that the working class must resolve this contradiction by seizing power in a revolution, to abolish class distinctions generally.

Friedrich Engels further proposed that nature itself is dialectical, and that this is "a very simple process, which is taking place everywhere and every day". His dialectical "law of the transformation of quantity into quality and vice versa" corresponds, according to Christian Fuchs, to the concept of phase transition and anticipated the concept of emergence "a hundred years ahead of his time". Stalin and Mao interpreted the transformation of quantity into quality not as a separate law, but as a special instance of the unity and struggle of opposites.

For Vladimir Lenin, the primary feature of Marx's "dialectical materialism" (Lenin's term) is its application of materialist philosophy to history and social sciences. Lenin's main contribution to the philosophy of dialectical materialism is his theory of reflection, which presents human consciousness as a dynamic reflection of the objective material world that fully shapes its contents and structure.

Later, Stalin's works on the subject established a rigid and formalistic division of Marxist–Leninist theory into dialectical materialism and historical materialism. While the first was supposed to be the key method and theory of the philosophy of nature, the second was the Soviet version of the philosophy of history.

Soviet systems theory pioneer Alexander Bogdanov viewed Hegelian and materialist dialectic as progressive, albeit inexact and diffuse, attempts at achieving what he called tektology, or a universal science of organization.

Dialectical naturalism

Dialectical naturalism is a term coined by American philosopher Murray Bookchin to describe the philosophical underpinnings of the political program of social ecology. Dialectical naturalism explores the complex interrelationship between social problems and the ecological consequences of human society. Bookchin offered dialectical naturalism as a contrast to what he saw as the "empyrean, basically antinaturalistic dialectical idealism" of Hegel, and "the wooden, often scientistic dialectical materialism of orthodox Marxists".

Theological dialectics

Neo-orthodoxy, in Europe also known as theology of crisis and dialectical theology, is a theological approach in Protestantism that was developed in the aftermath of the First World War (1914–1918). It is characterized as a reaction against doctrines of nineteenth-century liberal theology and a more positive reevaluation of the teachings of the Reformation, much of which had been in decline (especially in western Europe) since the late eighteenth century. It is primarily associated with two Swiss professors and pastors, Karl Barth (1886–1968) and Emil Brunner (1899–1966), even though Barth himself expressed his unease in the use of the term.

In dialectical theology, the difference and opposition between God and human beings is stressed in such a way that all human attempts at overcoming this opposition through moral, religious or philosophical idealism must be characterized as sin. In the death of Christ humanity is negated and overcome, but this judgment also points forwards to the resurrection in which humanity is reestablished in Christ. For Barth this meant that only through God's "no" to everything human can his "yes" be perceived. Applied to traditional themes of Protestant theology, such as double predestination, this means that election and reprobation cannot be viewed as a quantitative limitation of God's action. Rather it must be seen as its "qualitative definition".

Dialectic prominently figured in Bernard Lonergan's philosophy, in his books Insight and Method in Theology. Michael Shute wrote about Lonergan's use of dialectic in The Origins of Lonergan's Notion of the Dialectic of History. For Lonergan, dialectic is both individual and operative in community. Simply described, it is a dynamic process that results in something new:

For the sake of greater precision, let us say that a dialectic is a concrete unfolding of linked but opposed principles of change. Thus there will be a dialectic if (1) there is an aggregate of events of a determinate character, (2) the events may be traced to either or both of two principles, (3) the principles are opposed yet bound together, and (4) they are modified by the changes that successively result from them.

Dialectic is one of the eight functional specialties Lonergan envisaged for theology to bring this discipline into the modern world. Lonergan believed that the lack of an agreed method among scholars had inhibited substantive agreement from being reached and progress from being made compared to the natural sciences. Karl Rahner, S. J., however, criticized Lonergan's theological method in a short article entitled "Some Critical Thoughts on 'Functional Specialties in Theology'" where he stated: "Lonergan's theological methodology seems to me to be 'so generic that it really fits every science', and hence is not the methodology of theology as such, but only a very general methodology of science."

Criticisms

Friedrich Nietzsche viewed dialectic as a method that imposes artificial boundaries and suppresses the richness and diversity of reality. He rejected the notion that truth can be fully grasped through dialectical reasoning and offered a critique of dialectic, challenging its traditional framework and emphasizing the limitations of its approach to understanding reality. He expressed skepticism towards its methodology and implications in Twilight of the Idols: "I mistrust all systematizers and I avoid them. The will to a system is a lack of integrity". In the same book, Nietzsche criticized Socrates' dialectics because he believed it prioritized reason over instinct, resulting in the suppression of individual passions and the imposition of an artificial morality.

In 1937, Karl Popper wrote and delivered a paper entitled "What Is Dialectic?" in which he criticized the dialectics of Hegel, Marx, and Engels for their willingness "to put up with contradictions". He argued that accepting contradiction as a valid form of logic would lead to the principle of explosion and thus trivialism. Popper concluded the essay with these words: "The whole development of dialectic should be a warning against the dangers inherent in philosophical system-building. It should remind us that philosophy should not be made a basis for any sort of scientific system and that philosophers should be much more modest in their claims. One task which they can fulfill quite usefully is the study of the critical methods of science." Seventy years later, Nicholas Rescher responded that "Popper's critique touches only a hyperbolic version of dialectic", and he quipped: "Ironically, there is something decidedly dialectical about Popper's critique of dialectics." Around the same time as Popper's critique was published, philosopher Sidney Hook discussed the "sense and nonsense in dialectic" and rejected two conceptions of dialectic as unscientific but accepted one conception as a "convenient organizing category".

The philosopher of science and physicist Mario Bunge repeatedly criticized Hegelian and Marxian dialectics, calling them "fuzzy and remote from science" and a "disastrous legacy". He concluded: "The so-called laws of dialectics, such as formulated by Engels (1940, 1954) and Lenin (1947, 1981), are false insofar as they are intelligible." Poe Yu-ze Wan, reviewing Bunge's criticisms of dialectics, found Bunge's arguments to be important and sensible, but he thought that dialectics could still serve some heuristic purposes for scientists. Wan pointed out that scientists such as the American Marxist biologists Richard Levins and Richard Lewontin (authors of The Dialectical Biologist) and the German-American evolutionary biologist Ernst Mayr, not a Marxist himself, have found agreement between dialectical principles and their own scientific outlooks, although Wan opined that Engels' "laws" of dialectics "in fact 'explain' nothing".

Even some Marxists are critical of the term "dialectics". For instance, Michael Heinrich wrote, "More often than not, the grandiose rhetoric about dialectics is reducible to the simple fact that everything is dependent upon everything else and is in a state of interaction and that it's all rather complicated—which is true in most cases, but doesn't really say anything."

Formalization

Since the late 20th century, European and American logicians have attempted to provide mathematical foundations for dialectic through formalisation, although logic has been related to dialectic since ancient times. There have been pre-formal and partially-formal treatises on argument and dialectic, from authors such as Stephen Toulmin (The Uses of Argument, 1958), Nicholas Rescher (Dialectics: A Controversy-Oriented Approach to the Theory of Knowledge, 1977), and Frans H. van Eemeren and Rob Grootendorst (pragma-dialectics, 1980s). One can include works of the communities of informal logic and paraconsistent logic.

Defeasibility

Building on theories of defeasible reasoning (see John L. Pollock), systems have been built that define well-formedness of arguments, rules governing the process of introducing arguments based on fixed assumptions, and rules for shifting burden. Many of these logics appear in the special area of artificial intelligence and law, though the computer scientists' interest in formalizing dialectic originates in a desire to build decision support and computer-supported collaborative work systems.

Dialogue games

Dialectic itself can be formalised as moves in a game, where an advocate for the truth of a proposition and an opponent argue. Such games can provide a semantics of logic, one that is very general in applicability.

Mathematics

Mathematician William Lawvere interpreted dialectics in the setting of categorical logic in terms of adjunctions between idempotent monads. This perspective may be useful in the context of theoretical computer science where the duality between syntax and semantics can be interpreted as a dialectic in this sense. For example, the Curry–Howard correspondence is such an adjunction or more generally the duality between closed monoidal categories and their internal logic.

Epigenetics of anxiety and stress–related disorders

From Wikipedia, the free encyclopedia https://en.wikipedia.org/wiki/Epigenetics_of_anxiety_and_stress%E2%80%93related_disorder...