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Wednesday, February 13, 2019

Nuclear weapons in popular culture

From Wikipedia, the free encyclopedia

A nuclear fireball lights up the night in a United States nuclear test.
 
Since their public debut in August 1945, nuclear weapons and their potential effects have been a recurring motif in popular culture, to the extent that the decades of the Cold War are often referred to as the "atomic age".

Images of nuclear weapons

The now-familiar peace symbol was originally a specifically anti-nuclear weapons icon.

The atomic bombings of Hiroshima and Nagasaki ushered in the "atomic age", and the bleak pictures of the bombed-out cities released shortly after the end of World War II became symbols of the power and destruction of the new weapons (it is worth noting that the first pictures released were only from distances, and did not contain any human bodies—such pictures would only be released in later years).

The first pictures released of a nuclear explosion—the blast from the Trinity test—focused on the fireball itself; later pictures would focus primarily on the mushroom cloud that followed. After the United States began a regular program of nuclear testing in the late 1940s, continuing through the 1950s (and matched by the Soviet Union), the mushroom cloud has served as a symbol of the weapons themselves. 

Pictures of nuclear weapons themselves (the actual casings) were not made public until 1960, and even those were only mock-ups of the "Fat Man" and "Little Boy" weapons dropped on Japan—not the more powerful weapons developed more recently. Diagrams of the general principles of operation of thermonuclear weapons have been available in very general terms since at least 1969 in at least two encyclopedia articles, and open literature research into inertial confinement fusion has been at least richly suggestive of how the "secondary" and "inter" stages of thermonuclear weapons work.

In general, however, the design of nuclear weapons has been the most closely guarded secret until long after the secrets had been independently developed—or stolen—by all the major powers and a number of lesser ones. It is generally possible to trace US knowledge of foreign progress in nuclear weapons technology by reading the US Department of Energy document "Restricted Data Declassification Decisions - 1946 to the Present" (although some nuclear weapons design data have been reclassified since concern about proliferation of nuclear weapons to "nth countries" increased in the late 1970s). 

However, two controversial publications breached this silence in ways that made many in the US and allied nuclear weapons community very anxious. 

Former nuclear weapons designer Theodore Taylor described how terrorists could, without using any classified information at all, design a working fission nuclear weapon to journalist John McPhee, who published this information in the best-selling book The Curve of Binding Energy in 1974.

In 1979 the US Department of Energy sued to suppress the publication of an article by Howard Morland in The Progressive magazine detailing design information on thermonuclear and fission nuclear weapons he was able to glean in conversations with officials at several DoE contractor plants active in manufacture of nuclear weapons components. Ray Kidder, a nuclear weapon designer testifying for Morland, identified several open literature sources for the information Morland repeated in his article, while aviation historian Chuck Hansen produced a similar document for US Senator Charles Percy . Morland and The Progressive won the case, and Morland published a book on his journalistic research for the article, the trial, and a technical appendix in which he "corrected" what he felt were false assumptions in his original article about the design of thermonuclear weapons in his book, The Secret That Exploded. The concepts in Morland's book are widely acknowledged in other popular-audience descriptions of the inner workings of Thermonuclear weapons

During the 1950s, many countries developed large civil-defense programs designed to aid the populace in the event of nuclear warfare. These generally included drills for evacuation to fallout shelters, popularized through popular media such as the US film, Duck and Cover. These drills, with their images of eerily empty streets and the activity of hiding from a nuclear bomb under a schoolroom desk, would later become symbols of the seemingly inescapable and common fate created by such weapons. Many Americans—at least among the wealthier classes—built back-yard fallout shelters, which would provide little protection from a direct hit, but would keep out wind-blown fallout, for a few days or weeks (Switzerland, which never acquired nuclear weapons, although it had the technological sophistication to do so long before Pakistan or North Korea, has built nuclear blast shelters that would protect most of its population from a nuclear war.)

After the development of hydrogen bombs in the 1950s, and especially after the massive and widely publicized Castle Bravo test accident by the United States in 1954, which spread nuclear fallout over a large area and resulted in the death of at least one Japanese fisherman, the idea of a "limited" or "survivable" nuclear war became increasingly replaced by a perception that nuclear war meant the potentially instant end of all civilization: in fact, the explicit strategy of the nuclear powers was called Mutual Assured Destruction. Nuclear weapons became synonymous with apocalypse, and as a symbol this resonated through the culture of nations with freedom of the press. Several popular novels—such as Alas, Babylon and On the Beach—portrayed the aftermath of nuclear war. Several science-fiction novels, such as A Canticle for Leibowitz, explored the long-term consequences. Stanley Kubrick's film Dr. Strangelove or: How I Learned to Stop Worrying and Love the Bomb satirically portrayed the events and the thinking that could begin a nuclear war. 

Nuclear weapons are also one of the main targets of peace organizations. The CND (Campaign for Nuclear Disarmament) was one of the main organisations campaigning against the 'Bomb'. Its symbol, a combination of the semaphore symbols for "N" (nuclear) and "D" (disarmament), entered modern popular culture as an icon of peace.

In art

The power and the visual effects of atomic weapons have inspired many artists. Some notable examples include:

In comedy

The mushroom cloud is familiar enough to be treated with humor in a Les Paul advertising campaign.
  • The comedian/lyricist Tom Lehrer penned a number of humorous and well known songs relating to nuclear weapons. His song Who's Next? took up the issue of nuclear proliferation, chronicling the acquisition of nuclear weapons by various nations, then theorizing on "Who's Next," ending with Luxembourg, Monaco, and Alabama becoming nuclear powers, while We Will All Go Together When We Go looked at the brighter side of nuclear holocaust (not having to mourn over the death of others, since "if the bomb that drops on you gets your friends and neighbors too, there'll be nobody left behind to grieve"). It assumes that the entire planet will be instantaneously wiped clean by nuclear fire, and bypasses the much grimmer idea of radiation poisoning. A third song by Lehrer, "So Long Mom (A Song From World War III)", was introduced as existing because, "If any songs are going to come out of World War III, we had better start writing them now" and tells the tale of a young soldier marching off to nuclear war, promising his mother that "Although I may roam, I'll come back to my home/Although it may be a pile of debris" and also satirizing the likely extremely short duration of a major nuclear war ("And I'll look for you when the war is over/An hour and a half from now!").
  • "Weird Al" Yankovic also made a light-hearted spin on nuclear annihilation in his song Christmas at Ground Zero, which describes "A jolly holiday underneath a mushroom cloud".

In fiction, film, and theater

  • Nuclear weapons are a staple element in science fiction novels. The phrase "atomic bomb" predates their existence, back to H. G. Wells' The World Set Free (1914) when scientists had discovered that radioactive decay implied potentially limitless energy locked inside of atomic particles (Wells' atomic bombs were only as powerful as conventional explosives, but would continue exploding for days on end). Robert A. Heinlein's 1940 Solution Unsatisfactory posits radioactive dust as a weapon that the US develops in a crash program to end World War II; the dust's existence forces drastic changes in the postwar world. Cleve Cartmill predicted a chain-reaction-type nuclear bomb in his 1944 science fiction story "Deadline," which led to the FBI investigating him, due to concern over a potential breach of security on the Manhattan Project. (see Silverberg).
  • Many of the characteristics of nuclear weapons themselves have played on ages-old human themes and tropes (penetrating rays, persistent contamination, virility, and, of course, apocalypse), giving their standing in popular culture and politics a particularly emotional valence (both positive and negative). For example, the book Down to a Sunless Sea (1979 novel) is set in a post-holocaust environment, as what may be one of the last planeloads of survivors tries to find a place to land.
  • Nuclear weapons have even been featured in children's works: The Butter Battle Book, by Dr. Seuss, deals with deterrence and the arms race.
  • I Live in Fear, a 1955 Japanese film directed by Akira Kurosawa, is about a Japanese businessman who is terrified of nuclear war and was among the earliest films to deal with the psychological impact of nuclear weapons.
  • Many films, some of which were based on novels, feature nuclear war or the threat of it. Godzilla (1954) is considered by some to be an analogy to the nuclear weapons dropped on Japan, another pre-dating film The Beast from 20,000 Fathoms being the start of a more general genre of movies about creatures mutated or awakened by nuclear testing. Them! (1954) (giant ants in Los Angeles sewers) is based on a similar premise. The Incredible Shrinking Man (novel) (film, 1957) starts with a sailor irradiated by a bomb test, based on a real incident of irradiation of Japanese fisherman. In A Canticle for Leibowitz, (novel, no film, 1959) the previous war is known as the "Flame Deluge"; On the Beach (novel 1957, film 1959, television miniseries 2000) is most famous for making the end of humanity a theme in popular thinking on nuclear war; Final War (Japan, 1960) nuclear war erupts after the USA accidentally bombs South Korea. The 1962 film This is Not a Test addresses the reactions and emotions of a group of people in the minutes prior to a nuclear attack.
  • In the 2012 Marvel film The Avengers, Iron Man (Tony Stark), who is played by Robert Downey Jr., flies a nuke into the portal that the alien Chituari army controlled by the god Loki comes from.
  • Some non-fiction works of the time had an effect on cultural works. Herman Kahn's innovative non-fiction book On Thermonuclear War, (1961) described various nuclear war scenarios, including the possibility of a "Doomsday Machine" (a "thought experiment" described by Leo Szilard after the first Teller-Ulam thermonuclear weapon test, but before relatively small, deliverable thermonuclear weapons were developed in 1954). The 1964 film Dr. Strangelove or: How I Learned to Stop Worrying and Love the Bomb was a black comedy inspired by the Doomsday Machine meme and, loosely, by Peter George's 1958 novel Red Alert. (Menand, 2005). George later wrote the novelization of Dr. Strangelove, in which the action of the screenplay is framed by a story of aliens reconstructing the events leading to the death of the human race. Fail-Safe (novel 1962) (film 1964) (live-TV remake 2000) portrayed the accidental thermonuclear bombing of Moscow after failure of the US Air Force Strategic Air Command's nuclear command and control system. The Bedford Incident, a 1965 film based on the 1961 novel of the same name, depicts a tense game of naval cat and mouse in the far North Atlantic between the fictional destroyer USS Bedford and a Soviet submarine caught violating Greenland territorial waters. The novel ends as the Bedford accidentally fires an ASROC missile at the submarine, and the Soviet submarine responds by firing four nuclear torpedoes. The War Game (BBC TV film, 1965) was a mockumentary film about the effects of nuclear war on England. Pierre Boulle's 1963 novel Planet of the Apes was set on a far-future Earth ruled by apes after a nuclear war that destroyed mankind; the novel was adapted into a movie of the same name which spawned four sequels. Damnation Alley (1977), the movie adaptation of a Roger Zelazny short story. featured a chilling launch and destruction sequence, followed by a trek across a ruined America; Taiyō o Nusunda Otoko / The Man Who Stole the Sun (1979), When the Wind Blows (British graphic novel 1982, animated film 1986) is the story of a middle-aged British couple, Jim and Hilda, who naively assume that World War III will be no worse than World War II. Special Bulletin was a 1983 made-for-TV movie about anti-nuclear activists detonating a home built nuclear device in Charleston, South Carolina, the film was shot in a live breaking news show format.
The Day After became known for its realistic representation of nuclear war and groundbreaking special effects for a television movie.
  • The Day After (1983) was a "made for TV" movie that became fodder for talk shows and commentary by politicians at the time due to its depiction of the runup to a nuclear war between the US and the Soviets with graphic explosions on American soil, the aftermath of the attack and alleged political causes. Testament (1983), another postwar vision of survival in a small California town after WWIII; WarGames (1983), features a young computer hacker who nearly starts World War Three when he inadvertently breaks into a fictional NORAD supercomputer named WOPR (War Operation Plan Response) to play the latest video games; The Terminator (4 films, 1984, 1991, 2003, 2009) features a post-apocalyptic future in which artificial intelligence has become self-aware, identifies all humans as a threat and uses the worlds nuclear arsenal to destroy mankind.(all James Cameron films from 1986 through 1994 deal with nuclear explosions); Red Dawn (1984)film, directed by John Milius) a Soviet/Nicaraguan/Cuban invasion and occupation follows a surprise limited nuclear strike on the US (1984), Mad Max (4 films, 1979–2015), a loner Australian highway patrolman wanders a bleak violent post apocalyptic wasteland. Countdown to Looking Glass, (1984) a 'docudrama,' shows an international incident, the breakdown in diplomacy, the escalation in international tensions leading up to a nuclear crisis, the breakout of ground and naval combat overseas, and ends with the president taking off in the airborne E-4 command post ("Looking Glass") and the activation of the Emergency Broadcast System and air raid sirens. Manhattan Project (1986), is not about the actual The Manhattan Project but how, using stolen plutonium, a high school student builds an atomic bomb for a science class project. Threads (BBC TV production made 1984, shown 1985), based on British government exercise Square Leg, shows the effects of an all-out nuclear war on the town of Sheffield, England, UK. Project X (1987) deals with testing of lethal exposures to nuclear radiation on how specially-trained chimpanzees perform in computerized flight simulators (based on an actual US Air Force biomedical research program). In Miracle Mile (1988) a musician visiting the "Miracle Mile" area of Los Angeles receives a wrong number phone call and hears a conversation in the background saying that a nuclear attack on the United States is imminent. Denial, confusion, fear and panic ensue before the attack as the protagonist scrambles to save himself and a woman he met earlier in the day. By Dawn's Early Light (1990) portrays an accidental limited nuclear exchange between the US and the Soviet Union after a "false-flag" attack on Soviet territory by Russian ultra nationalist terrorists seemingly launched from a US base in Turkey, and attempts to stop hostilities before they spiral into an all-out nuclear war. Broken Arrow (1996) depicts the theft of two thermonuclear weapons by a rogue US bomber pilot. ("Broken Arrow" is military jargon for an accidental nuclear event which does not create the risk of a nuclear war; the theft of working nuclear weapons depicted in the film would actually be classified as an "Empty Quiver" by the US Department of Defense.).
  • The 1984 book The Fourth Protocol by Frederick Forsyth and its 1987 film describe a plan by lone and extreme Soviet government elements to encourage unilateral British disarmament. They smuggle the components of a small tactical nuclear bomb into Britain, to a deep-cover Russian spy who gathers them for assembly and eventual detonation near an American nuclear base, the week before a General Election.
  • The James Bond films are also known to have plots surrounding nuclear weapons. Films like Thunderball (1965), You Only Live Twice (1967), Diamonds Are Forever (1971), The Spy Who Loved Me (1977), Octopussy (1983), Tomorrow Never Dies (1997) and The World Is Not Enough (1999) involve nuclear weapons. Some are based around their threatened use or theft, others in a showdown between the superpowers. The threat is prevented by Bond in the nick of time, although weapons are detonated in The Spy Who Loved Me when two Polaris missiles each destroy a stolen nuclear submarine out at sea, British and Russian respectively. However, these do not harm the world's population or land, killing only the villain's crews in each stolen submarine. In Goldfinger (1964) the titular antagonist (with assistance from Chinese and North Korean agents who want economic collapse in the West) attempts to irradiate the US's national gold reserves stored at Fort Knox with an atomic bomb in order to increase the value of his own stockpile. The villain in Octopussy (1983) was a power-mad renegade Soviet general opposed to disarmament talks with NATO, who aided by Afghan and Indian smugglers hatches an elaborate plot to invade Western Europe after the clandestine placement and seemingly accidental detonation of a nuclear weapon on a US Air Force base in West Germany. GoldenEye (1995) focuses on a nuclear satellite weapon that unleashes a powerful electromagnetic pulse attack upon whatever area it is detonated over, destroying anything with an electronic circuit. The tendency to have plots revolving around nuclear weapons is observed in the spoof film series Austin Powers, where after considering various evil schemes, antagonist Dr. Evil finally remarks, "Let's just do what we always do; steal a nuclear bomb and hold the world to ransom."
  • There have been a few fictionalized accounts of historical events relating to nuclear weapons as well. The Manhattan Project itself, for example, was depicted in both the 1989 theatrical film Fat Man and Little Boy and, somewhat more in-depth, also released in 1989 the CBS television film Day One.The films The Missiles of October (ABC TV 1974) and the theatrical release Thirteen Days (2000) dramatize the tensions of the 1962 Cuban missile crisis from the standpoint of Pres. Kennedy's Cabinet.
  • Since the end of the Cold War, alternate history has often shown how nuclear war could have arisen for certain crises. In the 1998 German-American mockumentary Der dritte Weltkrieg, Mikhail Gorbachev is ousted during his October 1989 visit to East Germany, after which the new hardline government violently suppresses or preempts the Revolutions of 1989, and starts a seemingly contained conventional war which leads to an accidental nuclear exchange; the film then rewinds to show Gorbachev in East Berlin and ends with jubilant scenes from the "different path" of recorded history. In 2013's What If...Armageddon 1962, John F. Kennedy is assassinated before becoming President (killed by an actual would-be assassin who lost his nerve after realizing his attack would also kill Kennedy's wife and children), and under Lyndon B. Johnson's leadership, the Cuban Missile Crisis leads to an all-out nuclear attack on the Soviet Union.
  • The second season of the television series 24 involves Muslim terrorists smuggling a nuclear bomb across the Mexican border and planning to detonate it in Los Angeles. In the fourth season, after a series of terrorist attacks, a group of Islamic terrorists capture and launch a nuclear cruise missile at Los Angeles. The sixth season also involves nuclear weapons as a major theme, with a group of terrorists having access to five nuclear suitcase bombs.
  • Nuclear weapons, both conventional and "enhanced" (through the use of fictional advanced technology), are used in the feature film Stargate and the related television series Stargate SG-1 and Stargate Atlantis.
  • The Tom Clancy novel and movie The Sum of All Fears depicts a nuclear explosion caused by Islamic terrorists in Denver (novel) or by neo-Nazis in Baltimore (film).
  • The movie On The Beach is based around the premise of a nuclear war. In the original novel, the war starts as a "catalytic war" caused by Egyptian airmen destroying Washington, DC in Russian-built bombers, causing mistaken retaliation against the Soviet Union and a general nuclear exchange. In the 2000 Australian remake of On The Beach, a nuclear war is fought between the United States of America and the People's Republic of China over a Chinese invasion of Taiwan.
  • In the comic The Invisibles, writer Grant Morrison references Oppenheimer using the "Destroyer of Worlds" quote as a mystic phrase and using the moment of detonation as part of a magical ritual. The roleplaying game GURPS Technomancer repeats this theme, depicting an alternate history where Oppenheimer unwittingly completes a necromantic ritual that releases magic back into the world at Trinity. The CBS television drama Jericho (2006) focuses on a small town that is left without communications and basic necessities after a nuclear attack on major US cities. The 2006 film The Hills Have Eyes features a group of miners' descendants in the New Mexico desert, who have become genetically mutated due to the radiation caused by the atomic tests, and terrorize travelers in the area, who are lured to their mines in the hills by a gas station owner who profits from the victim's jewelry.
  • There have also been a number of plays set around the theme of nuclear weapons development. Michael Frayn's Tony Award-winning Copenhagen (1998), for example, contemplates the ethics and early history of nuclear weapons development through the eyes of the physicist Niels Bohr, his wife Margarethe, and his former pupil Werner Heisenberg. Swiss playwright Friedrich Dürrenmatt addressed the question of the responsibility of scientists in a post-Hiroshima world explicitly in his 1961 satire, Die Physiker. The rise-and-fall of American physicist and "father of the atomic bomb" J. Robert Oppenheimer has been the subject and inspiration of a number of plays—Heinar Kipphardt's In the Matter J. Robert Oppenheimer (1964), PBS's American Playhouse's 7 part "Oppenheimer" (1982), and even an opera, Doctor Atomic (2005).
  • In Indiana Jones and the Kingdom of the Crystal Skull (2008), set in 1957, Indiana Jones finds himself at the Nevada test site just before an atomic test. Chased by Soviet soldiers, he wanders into an area set up to resemble a suburban town when hearing an air raid siren, then he realizes that it is only a matter of seconds before an atomic detonation, so he locks himself in a lead-lined refrigerator. The explosion flings the refrigerator a safe distance away, where Jones emerges without any serious injuries.
  • The third episode of Lost's fifth season, "Jughead," reveals that the United States military brought a hydrogen bomb called Jughead to the island in 1954; the military troops were killed by the Others and the bomb was seized. A time-traveling Daniel Faraday convinces the Others that he is part of a military science team sent to defuse the bomb, which is leaking radioactive material, but eventually confides to one of their members that the bomb must be buried underground after being sealed with lead or concrete, explaining that he knows this will work because the island is still intact 50 years later, having never been destroyed in a nuclear blast. However, in 1977, the bomb was used in an attempt to stop the Incident, in the hope of changing the future.
  • In the movie Back to the Future, Marty McFly, in 1955, is showing Doc Brown a video made in 1985 in which Marty and the future Doc Brown are wearing radiation suits. Doc Brown surmises that the radiation suits are worn to protect himself and Marty from the fallout "from all the atomic wars" (presumably referring to the fact that the 1955 Doc Brown is living during the Cold War).
  • In the 2004 reimagining of the television series Battlestar Galactica, nuclear weapons are a recurring weapon in the arsenal of both the Human and Cylon forces, though the Cylons use the weapons in colossal force when they bombard the Twelve Colonies with nuclear weapons, wiping out almost all life on the twelve planets. While the Galactica is stated to possess five nuclear warheads shortly after they flee the destroyed Twelve Colonies, (though it is later shown to carry six, possibly having been given several from the Battlestar Pegasus), the Cylons possess an unknown number, though given the sheer amount of the nukes used to devastate the Twelve Colonies, it is estimated that they possess many thousands.
  • In Part 8 (Twin Peaks), The Trinity Nuclear Test facilitates the birth of Killer BOB, and the conception of Laura Palmer by The Fireman, leading in to the events of the TV series and Twin Peaks: Fire Walk With Me.

In literature and books

Fourteen months after the bombing of Hiroshima and Nagasaki, Fawcett Comics produced a story dealing with the destructive potential of nuclear weaponry.
  • Walter Miller, Jr.'s A Canticle for Leibowitz follows the history of an order of monks founded to save human knowledge after a nuclear war plunged society into savagery. Scientist Isaac Edward Leibowitz founded the order, and was martyred for smuggling books. A long-lived Jewish man hinted to be St. Lazarus of Bethany or St. Leibowitz appears to the order at least three times over several centuries. At the end of the novel, civilization re-invents nuclear weapons. Leibowitz's order goes to a planet around another star with orphaned children and the core of a new Church to preserve civilization as all life dies on Earth during its last nuclear war.
  • Superman—A 1944 story involving Lex Luthor using an atomic bomb against Superman was put on hold until 1946 by the War Department. It was later mentioned this would have been good subterfuge. Artist Wayne Boring drew the "Superman Covers Atom Bomb Test!" cover for Action Comics #101 (Oct. 1946).
  • The Secret of the Swordfish—by Edgar P. Jacobs, first album of the Belgian comic strip Blake and Mortimer, depicts a 20th-century World War in which the fictional Asian "Yellow Empire" nearly conquers the entire world. It ends with the destruction of the Yellow Empire's capital while the Emperor plans to launch his nuclear weapons. The Time Trap and The Strange Encounter, later albums of Blake and Mortimer, deal with time-travel and a future where Earth is devastated by a nuclear war.
  • Watchmen by Alan Moore is set in an alternative history where the US and USSR edge dangerously close to nuclear war.
  • The graphic novel for adults When the Wind Blows by children's author Raymond Briggs follows a retired couple in the days just after a thermonuclear war.
  • Arc Light is a technothriller by Eric L. Harry about a limited nuclear exchange between the United States and Russia.
  • Command the Morning[13] is a 1959 fictionalization of the Manhattan Project by Pearl S. Buck, winner of the Nobel Prize in Literature.
  • "Emerald City Blues" is a short story by Steve Boyett published in the Fall 1988 issue of Midnight Graffiti, which dramatizes the horrors of nuclear war by describing the effects of an atom bomb dropped on Oz; the fallout kills Dorothy Gale, protagonist of L. Frank Baum's The Wonderful Wizard of Oz.
  • Several novels by Dale Brown have use of nuclear weapons as pivotal plot elements. Among them are Sky Masters, in which a Chinese warship uses a tactical nuclear weapon to destroy a Philippine naval task force in the South China Sea; in Fatal Terrain, China launches attacks Taiwan and on Andersen Air Force Base in Guam with nuclear weapons; Chains of Command portrays a Russian nuclear attack on the Ukraine. Later, the Ukraine destroys a Russian bunker with a nuclear weapon. Plan of Attack, features a Russian bomber attack on US air bases, the headquarters of the US Strategic Command, and several cities in the United States with nuclear weapons, in revenge for an attack on Engels Air Base described in an earlier novel, Air Battle Force.
  • The Japanese Manga, Barefoot Gen written by Keiji Nakazawa and adapted into an Anime by the same name takes place in 1945 in and around Hiroshima, Japan, where the six-year-old boy Gen lives with his family. After Hiroshima is destroyed by atomic bombing, Gen and other survivors must deal with the aftermath. The story is loosely based on Nakazawa's own experiences as a Hiroshima survivor.
  • The Manga and Anime franchise Hokuto no Ken (Fist of the North Star) takes place in an alternate future after a nuclear war in the 1990s leaves a wasteland ruled by warbands of mutants and tyrannical martial arts masters.
  • Ender's Game portrays use nuclear weapons during the war with the alien Formics with references to "The nuking of Mecca" and to a protective technology against nuclear weapons - "The shields make it so no one bothers with nuclear weapons anymore."
  • The Valley-Westside War by Harry Turtledove is an alternate history set after a nuclear war between the United States and the USSR in 1967, L.A.'s San Fernando Valley is reduced to a collection of primitive warring feudal states.
  • In Halo: Ghosts of Onyx the character Kurt detonates two nuclear warheads on Onyx. Also, a "NOVA bomb" (composed of multiple nuclear devices in a special casing) destroys part of the Sangheili fleet.
  • Nineteen Eighty-Four, a novel by George Orwell is set in a Britain (described as "Airstrip One"), the seat of one of three dictatorships vying for control of Earth in an endless series of regional conflicts waged after a nuclear war in the 1950s.
  • Y = Arctg X: The Hyperbola of the World Order by historian Max Ostrovsky, outlines macro-historical and geopolitical forces which Ostrovsky contends will inexorably lead to total nuclear war between the Western and Eastern Hemispheres, ending either in nuclear apocalypse or the nuclear genesis of a World State.
  • C. S. Lewis's Chronicles of Narnia novel The Magician's Nephew features the "Deplorable Word," a thinly-veiled criticism of nuclear warfare. Said with the "proper ceremonies," it destroys all life forms in the world except the speaker. The only known speaker of the Deplorable Word is the White Witch, Jadis, the villain of previous Chronicles of Narnia.
  • Jean-Hugues Oppel's Réveillez le président ! (in French, Éditions Payot et rivages, 2007, ISBN 978-2-7436-1630-4) is about France's nuclear weapons.
  • The Iron Dream by Norman Spinrad is set 1142 years after a nuclear war. Near the end of the novel, the protagonists fail to prevent the detonation of a nuclear doomsday device left over from the earlier conflict.

In music

Along with other forms of culture, there have been many songs related to the topic of nuclear weapons and warfare. Many of them have been protest songs or warning songs, while others use the motif as an allusion to great destruction in general. 

Some of the more famous nuclear war songs include: "99 Luftballons" (1983) by the German group Nena, which depicts accidental nuclear war begun by an early-warning system identifying a group of balloons with enemy bombers or missiles; and Bob Dylan's "A Hard Rain's a-Gonna Fall" (1963), which premiered shortly before the Cuban Missile Crisis. He also made reference to nuclear weapons in his song "With God on Our Side" released as the third track on his 1964 album The Times They Are a-Changin'."But now we have weapons, of chemical dust...if fire them we're forced to...then fire them we must...". In many cases the allusions to nuclear war are not explicit, however. Iron Maiden's "Brighter than a Thousand Suns", on their album A Matter of Life and Death is a recent example. Steely Dan's "King of the World," on the album Countdown to Ecstasy is an example of upbeat music and very downbeat lyrics which give a very bleak picture of the post-nuclear world.

Heavy metal as a genre has been concerned with nuclear warfare since the days of Black Sabbath. Their classics, "War Pigs" and "Electric Funeral", respectively, are among the first metal songs to describe war, political corruption and atomic holocaust. In the early eighties, Iron Maiden wrote a number of songs which described nuclear war including "2 Minutes to Midnight" (a song about the doomsday clock), and the aforementioned "Brighter than a Thousand Suns" to name a few. The theme continued in heavy metal through the early nineties, especially in the thrash metal subgenre. Metallica wrote many popular songs about nuclear war and political corruption such as "Fight Fire with Fire", "...And Justice For All", and "Blackened". Megadeth's name is taken from the term "megadeath," used to describe one million deaths from a nuclear weapon, and much of their album artworks and songs deal with nuclear war and weapons. Other thrash bands such as Sodom and Anthrax also wrote a number of songs on the topic. The genre even inspired bands like Nuclear Assault and Warbringer to adopt the subject in their band names themselves. This trend also spread to Eastern European metal with popular Russian metal band Aria writing the song "Last Sunset" (Последний). 

The emerging punk movement explicitly tackled issues surrounding nuclear warfare. With many punks exhibiting an explicitly pacifist world view there was a need to challenge the conventional wisdom of nuclear deterrence and deployment. Much of this sentiment can be found in British punk bands, especially those emerging from the crust punk subgenre such as Amebix or Antisect and the related anarcho-punk subgenre where bands like Flux of Pink Indians made clear their opposition to nuclear warfare. 

Among the many songs alluding to nuclear weapons and nuclear war in the 1980s was the song "Manhattan Project" (1985) by the band Rush, one of the few songs with copious literal references to historical events leading to the first nuclear weapons. Additionally the band has a song about the possibility of nuclear war entitled "Distant Early Warning", the video of which features nuclear-related imagery. 

Orchestral Manoeuvres in the Dark's 1980 song "Enola Gay" depicts the events of the 1945 deployment of nuclear weapons on Hiroshima from the point of view of the crew of the B29 Superfortress Bomber Enola Gay. Clear references are made to the exact time the bomb detonated ("It's eight fifteen, and that's the time that it's always been"), and questions are asked as to whether the action was necessary. The song also references a supposed radio message in which the crew detail no anomalies as a result of nuclear detonation ("We got your message on the radio - conditions normal and you're coming home"); the American government denied any rumours of radiation sickness associated with the dropping of the bombs. 

Alternative rock band 10,000 Maniacs released the song "Grey Victory" on their 1985 major label debut album The Wishing Chair, in which the Enola Gay is described as having made a "casual delivery" and dispassionately describes the effects of the atomic bomb on Hiroshima, perhaps as a cynical response to the seeming general acceptance and lack of outrage in an age living with the threat of nuclear disaster ("Please build a future, darling, with our bomb/Cherish and love it for the sake of earth-bound kingdom come"). 

The band Pink Floyd produced a song titled "Two Suns in the Sunset", which indirectly references a nuclear attack. This song was the last of the predominantly war-themed album The Final Cut (1983). In addition, Roger Waters continued his commentary on the threat of nuclear war on his 1987 solo concept album Radio K.A.O.S., where a simulated nuclear strike is depicted as a warning in the song "Four Minutes". 

The 1980 song "Breathing" by Kate Bush is about a foetus, very much aware of what is going on outside the womb and frightened by nuclear fallout. The track includes spoken words describing the flash from a nuclear bomb. 

Sting released the song "Russians" in 1985 directly addressing Cold War tensions and the policy of "Mutually Assured Destruction (MAD)". "Russians" was not only a humanized expression of the Cold War conflict, pitting the fate of actual people against political rhetoric, but expressed the deep misunderstanding of political forces in calculating ordinary people's aspirations to live in peace ("I hope the Russians love their children, too"). 

"To Have and to Hold" from the 1987 album Music for the Masses from Depeche Mode opens with an excerpt from Soviet broadcast, which can be translated as: "Evolution of nuclear arsenals and socially-psychological aspects of arms race is considered in these reports." When asked whether it was used to make a political statement, Alan Wilder said that the band didn't know what the phrase meant at the time of recording.

Satirical artists such as Tom Lehrer and "Weird Al" Yankovic have drawn upon the motif of nuclear war for humor in their songs (as discussed in the 'Comedy' section). 

The album cover for the single "Teenagers" by My Chemical Romance is a mushroom cloud. The image also appears in the video for the song. 

The glam metal band Warrant released a song off their 1992 album Dog Eat Dog entitled "April 2031" which depicts life after a nuclear holocaust. 

Ska punk band RX Bandits make a reference to Nuclear War in their song "Nugget" with the line "Its 3 Years til I'm 24 and i don't wanna die in a Nuclear War" 

Irish rock band U2 also named their 2004 album How to Dismantle an Atomic Bomb

The song "Wendy Clear" from blink-182's 1999 album Enema of the State mentions a "nuclear device". 

Linkin Park's 2010 album A Thousand Suns deals with nuclear warfare and themes of war in general.

In video games

  • Several RTS games have the possibility to use nuclear devices as "superweapons"; the Command & Conquer series, Empire Earth, Supreme Commander, and Total Annihilation are typical examples.
  • Several games, including Fallout 3, the Ratchet & Clank series, and the Unreal series feature a tactical nuclear missile or grenade launcher that the player can find (or upgrade to) and use. This seems to be a reference to the real-life man-portable Davy Crockett tactical nuclear weapon.
  • The Ace Combat Series featured nuclear strikes. Example: in Ace Combat Zero: The Belkan War, Belka, a fictional antagonist country, detonated seven nuclear warheads to fend off Allied troops.
  • Frontlines: Fuel of War includes the detonations of two tactical nuclear warheads to destroy American tank battalions.
  • The game Balance of Power, written by Chris Crawford and published in 1985 puts the player in the position of the President of the United States or the General Secretary of the Soviet Union, with the goal of increasing "prestige", balanced out by the need to avoid a nuclear war, which ends the game.
  • In Battlefield 3, the main antagonist, Solomon, buys three portable nuclear devices from Amir Kaffarov, a Russian arms dealer, and detonates one in Paris in the mission "Comrades" which kills 80,000 people. The player finds one of them in mission "Operation Guillotine", and the last one in the mission "The Great Destroyer". The player also sees the nuke detonating in Paris and a picture of its mushroom cloud in the starting cut scene of "Thunder Run".
  • In Call of Duty: Modern Warfare 2, Captain Price launches a nuclear missile out of a nuclear submarine - however, instead of attacking land, he detonates it in the stratosphere, destroying the International Space Station and creating an electro-magnetic pulse throughout the eastern seaboard of the United States in order to disable all invading Russian tech sources and turn the tide of battle in America's favor. Also, in multiplayer gameplay, a person that has received 25 kills (or 24 with the second tier perk upgrade called hardline) without dying can call in a "tactical nuke" to end the game. There is also a hidden game mode in multiplayer that is very difficult to access in any public multiplayer game, entitled Global Thermonuclear War, in which opposing teams fight for control of a backpack nuke and a mutual bomb site similar to the Demolition game mode; the nuclear bomb takes considerably longer for each team to plant, and after successful detonation of the device, the game ends similarly as it would if someone detonated a tactical nuke in normal gameplay outside of the hidden game mode.
  • In Call of Duty: Modern Warfare 3, the game's antagonist, Vladimir Makarov, captures the Russian president in an attempt to extract Russia's nuclear launch codes from him.
  • In Call of Duty 4: Modern Warfare, a group of the warlord Al-Asad's forces in Saudi Arabia under occupation by the USMC detonate a Russian nuclear warhead, annihilating themselves, the capital city and nearly the entire invading US Marine force. Later in the game, the USMC must work together with the SAS to stop two SS-27 Topol M missiles, loaded with MIRVs, sent by the Russian ultranationalist forces, from destroying eight US cities: Boston, Hartford, New York, Philadelphia, Richmond, Norfolk, Baltimore and Washington, D.C. - which would kill more than 40 million people.
  • The Civilization series features nuclear weapons as a possible area of research in their extensive "tech trees." A player must construct their own version of the Manhattan Project to unlock the construction of nuclear weapons; afterward all players with sufficient technology can build nuclear weapons. In all versions of Civilization the use of nuclear weapons destroys all units in the area that was attacked, pollutes the surrounding area, and contributes to global warming. A nuclear attack on or near a city decreases the population of the city rather than annihilating it (Civilization Revolution has a single ICBM which can destroy cities and in Civilization V, nuclear weapons will destroy a city with a population rating lower than 3). In all Civilization games, the use of nuclear weapons can result in harsh diplomatic penalties.
  • The Soviets in both Command & Conquer: Red Alert and Command & Conquer: Red Alert 2, the Brotherhood of Nod in Command & Conquer and Command & Conquer 3: Tiberium Wars, and the Chinese in Generals can launch small tactical missiles to destroy key units and buildings, although the destruction is nowhere near its real-life counterpart. However, in Red Alert one mission requires the player prevent a strategic nuclear strike on Paris, and in Red Alert 2, the Soviets successfully destroy Chicago with a large nuclear bomb. In the game's expansion pack, Yuri's Revenge, the main villain nukes Seattle, Washington several times to extort money from a computer corporation. In a mod for C&C Generals Zero Hour, called 2015, Waste Land Conflict, the game features a nuke that is very realistic in damage and creates an EMP wave.
  • The 2006 game DEFCON by UK-based independent developer Introversion Software puts the player in charge of one of six world territories in a situation which inevitably deteriorates to global thermonuclear war. The game uses a graphical and audio style which deliberately evokes images from films such as WarGames, cited by the developers as a major inspiration. With the sense that nuclear war is being commanded by distant generals in deep underground bunkers using abstract images, the game gives an unsettling impression of how popular culture imagined nuclear war would look to the people responsible for starting it. Because "Everybody Dies", DEFCON is extremely difficult to win, as all sides will inevitably suffer nuclear attack. In the game's terminology, the victor is the player who 'loses the least'.
  • The Fallout series of computer games contains numerous direct and indirect allusions to nuclear wars and potential nuclear holocaust, with a distinct 1950s cold war style. The games themselves are set in a post-nuclear war wasteland where human civilisation has been ended by a nuclear conflict between the US and China, and the main character of the first game is a 'Vault Dweller', a survivor from a self-contained nuclear shelter. The first two games contain devices resembling the Trinity "Gadget" as central plot elements, and during one of the main quests in Fallout 3, the player must decide whether to detonate or disarm a nuclear bomb resembling the Fat Man in the center of a town called "Megaton."
  • In Grand Theft Auto V, the Doomsday Heist DLC ends with Avon Hertz, an American tech mogul, attempting to launch a nuclear missile from a secret launch facility hidden in Mount Chiliad, which the player has to stop.
  • Guerre Nucléaire (translates, from French, as Nuclear War) is an interactive fiction game. This text game is a simulation of a war between the USSR and USA.
  • In Half-Life: Opposing Force, at the end of the game, Adrian Shephard is being transported in a helicopter away from Black Mesa, accompanied by G-Man. As G-Man says The biggest embarrassment has been Black Mesa facility, but I think that's finally taken care of itself., there is a sudden flash of light visible, coming presumably from the direction of Black Mesa.
  • In the popular Halo franchise of video games and novels, nuclear weapons, from hand-held to planet-devastating, are used in both space and land combat by the United Nations Space Command.
  • The flight simulator F/A 18, Korea Gold, includes nuclear strike missions using the B61 tactical thermonuclear weapon.
  • In the game Mass Effect the player character, Commander Shepard, uses a "repurposed" starship drive core to destroy an alien cloning facility, and recovers a human thermonuclear booby trap of a human scout probe.
  • In Mass Effect 3 a massive, two-millennia old turian nuclear munition is uncovered by the human-supremacist group Cerberus, who proceed to attempt to detonate it in the densely populated area in which it had been left behind. The detonation is prevented by a turian detaching the implosion array, which then harmlessly explodes.
  • In Mercenaries 2: World in Flames, the main objective of the player is to obtain a nuclear bunker buster to penetrate the main enemy's hardened bunker (after which the bomb can be purchased and used according to the player's wishes).
  • The Metal Gear Solid Series by Konami, revolves around Metal Gear, a weapon described as a giant solo-operating tank capable of firing nuclear missiles at any target on the planet's surface.
  • In Metal Gear Solid 3: Snake Eater the primary antagonist, Colonel Volgin, obtains two M-388 Davy Crockett nuclear rifles. He then uses one of them to destroy half of a forest and cover up the theft.
  • The game Metro 2033, a first-person shooter based on Dmitry Glukhovsky's novel of the same title, takes place in a nuclear war ravaged Moscow and its metro tunnels. Radiation has made the upper world toxic and has mutated the wildlife. The player, Artyom, can choose to spare the mutants or destroy them with nuclear missiles.
  • In Metroid Prime 3: Corruption, a mission requires Samus Aran, the game's main protagonist, to use her ship to collect 3 pieces of a thermonuclear bomb needed to break a force field blocking her way to a boss fight.
  • In the game Missile Command the player must defend a city against a never ending series of incoming nuclear missiles.
  • In Nuclear Strike, the third level begins in Pyongyang, North Korea. It is revealed that a nuclear bomb has been smuggled inside Kim Il-sung's giant statue at Mansudae Hill and the player has to escort as many diplomats out of the city as possible before the bomb detonates.
  • In the game Nuclear War, a turn-based strategy game, the player takes part of a satirical and cartoonish nuclear battle between five world powers.
  • In Rise of Nations: Thrones and Patriots you can access nuclear missiles once you are at an advanced enough age. Each launched nuke reduces the so-called "Armageddon timer" by 1, and when it reaches zero, the game instantly ends with "Armageddon", causing every player to lose the game. (Simulating the effects of a nuclear winter)
  • In a few Shin Megami Tensei titles, nuclear weapons have destroyed the world and became responsible for creating a dimensional rift that allowed demons to cross over.
  • In the 2007 4X-RTS Sins of a Solar Empire the Trader Emergency Coalition (the game's "baseline human" faction, as opposed to psychic transhumans or aliens) uses nuclear weapons fairly liberally, for space-to-space combat, including nuclear torpedoes for anti-structure attacks, and for planetary bombardment, including salted bombs.
  • In the game Splinter Cell: Double Agent there is a possible ending with two events where the player must disarm a nuclear bomb, one in the JBA headquarters, another on a boat. One of the mission failure scenes shows New York City being destroyed in an explosion.
  • In Spore's Civilization stage, militaristic nations may use two types of nuclear weapon once certain prerequisites have been fulfilled - the Gadget Bomb, which can wipe out all structures of a city and capture it instantly, and the ICBM, which can be used to wipe out every nation on the planet simultaneously, winning the stage. The Gadget Bomb severely impacts international relations, and both weapons produce indestructible radioactive rubble.
  • In the StarCraft series, the Terran can construct laser-guided nuclear missiles for Ghost units to deploy. Several locations in StarCraft's backstory were affected by nuclear attacks prior to the events of the game.
  • In the ThirdWire series of combat flight simulators (Strike Fighters: Project 1, and the games descended from it) there are several downloadable modification which allow the player to use nuclear weapons. Free falling bombs, air-to-surface missiles, air-to-air missiles, and air-to-air rockets are covered in these modifications. American, British, Russian and French weapons are provided (with the range of American weapons being the most comprehensive). A variety of effects packages are available to provide the appropriate visual representation of the nuclear explosion. Several of aircraft in the ThirdWire series were either designed as, or came to be used as nuclear weapons carrying aircraft including the F-101 Voodoo, F-89 Scorpion, and B-29 Superfortress.
  • In the RTS Supreme Commander and its expansion pack Forged Alliance, all of the factions have strategic nuclear missiles. In addition, many nuclear-powered units explode with the blast of one.
  • In the games Syphon Filter: The Omega Strain and the original Syphon Filter both end with either the player or Gabe Logan having to disarm a nuclear missile.
  • In Tom Clancy's EndWar Saudi Arabia and Iran have destroyed each other with nuclear weapons, setting the basis for the storyline of the game.
  • In the game Tomb Raider the game's antagonist, Jacqueline Natla, is released from her prison by a nuclear weapons test.
  • Trinity was a text adventure game that featured a plotline involving time travel to various sites related to nuclear weapons. The title refers to the Trinity test site.
  • In the games Tropico 3, Tropico 4 and Tropico 5, nuclear testing is available as edict.
  • In Twisted Metal 4, the playable character Calypso drives a truck where its special attack is to launch the nuclear missile it carries.
  • In the RTS War Front: Turning Point, the Allied faction's super weapon is a small nuclear bomb dropped from a Northrop YB-35, that unleashes a small sized yet long lasting damaging blast.
  • In Warhammer 40,000, nuclear weapons are used to cause widespread damage to a planet (the methods collectively being called an "Exterminatus", a mass execution of a population through futuristic weapons) and in combat. The nukes must be properly arranged in orbit to create a global firestorm.
  • The RTS game Warzone 2100 is set after a nuclear holocaust initiated by an intelligent computer virus known as Nexus.
  • In the Microsoft Windows strategy game World in Conflict, the United States uses tactical nuclear weaponry to halt the advance of the Soviet Union in America. The weapons are also available in multiplayer games.
  • In Wolfenstein: The New Order in the year 1948, the Nazis build "the most powerful atomic bomb in history" and order it to be dropped onto New York City in the United States. The atomic bomb destroys the island of Manhattan and kills 200,000 people, this then forces the United States to surrender to the Nazis, winning World War II and subsequently taking over the world.
  • In one of the endings of Far Cry 5, the protagonist of the game attempts to arrest the antagonist Joseph Seed, however upon approaching him for his arrest, Seed describes a doomsday scenario as a nuke detonates in the backdrop of Montana. The scene then transitions to a race for a nearby bunker in which nukes are dropped from each direction, devastating the fictional town of Hope County, Montana.

Bioterrorism

From Wikipedia, the free encyclopedia

United States Airman wearing an M-17 nuclear, biological, and chemical warfare mask and hood
 
Bioterrorism is terrorism involving the intentional release or dissemination of biological agents. These agents are bacteria, viruses, fungi, or toxins, and may be in a naturally occurring or a human-modified form, in much the same way in biological warfare.

Definition

According to the U.S. Centers for Disease Control and Prevention, bioterrorism is the deliberate release of viruses, bacteria, toxins or other harmful agents to cause illness or death in people, animals, or plants. These agents are typically found in nature, but could be mutated or altered to increase their ability to cause disease, make them resistant to current medicines, or to increase their ability to be spread into the environment. Biological agents can be spread through the air, water, or in food. Terrorists tend to use biological agents because they are extremely difficult to detect and do not cause illness for several hours to several days. Some bioterrorism agents, like the smallpox virus, can be spread from person to person and some, like anthrax, cannot.

Bioterrorism is an attractive weapon because biological agents are relatively easy and inexpensive to obtain, can be easily disseminated, and can cause widespread fear and panic beyond the actual physical damage. Military leaders, however, have learned that, as a military asset, bioterrorism has some important limitations; it is difficult to use a bioweapon in a way that only affects the enemy and not friendly forces. A biological weapon is useful to terrorists mainly as a method of creating mass panic and disruption to a state or a country. However, technologists such as Bill Joy have warned of the potential power which genetic engineering might place in the hands of future bio-terrorists.

The use of agents that do not cause harm to humans but disrupt the economy have been discussed. A highly relevant pathogen in this context is the foot-and-mouth disease (FMD) virus, which is capable of causing widespread economic damage and public concern (as witnessed in the 2001 and 2007 FMD outbreaks in the UK), whilst having almost no capacity to infect humans.

Twentieth century

By the time World War I began, attempts to use anthrax were directed at animal populations. This generally proved to be ineffective.

Shortly after the start of World War I, Germany launched a biological sabotage campaign in the United States, Russia, Romania, and France. At that time, Anton Dilger lived in Germany, but in 1915 he was sent to the United States carrying cultures of glanders, a virulent disease of horses and mules. Dilger set up a laboratory in his home in Chevy Chase, Maryland. He used stevedores working the docks in Baltimore to infect horses with glanders while they were waiting to be shipped to Britain. Dilger was under suspicion as being a German agent, but was never arrested. Dilger eventually fled to Madrid, Spain, where he died during the Influenza Pandemic of 1918. In 1916, the Russians arrested a German agent with similar intentions. Germany and its allies infected French cavalry horses and many of Russia’s mules and horses on the Eastern Front. These actions hindered artillery and troop movements, as well as supply convoys.

In 1972 police in Chicago arrested two college students, Allen Schwander and Stephen Pera, who had planned to poison the city's water supply with typhoid and other bacteria. Schwander had founded a terrorist group, "R.I.S.E.", while Pera collected and grew cultures from the hospital where he worked. The two men fled to Cuba after being released on bail. Schwander died of natural causes in 1974, while Pera returned to the U.S. in 1975 and was put on probation.

In 1980 the World Health Organization (WHO) announced the eradication of smallpox, a highly contagious and incurable disease. Although the disease has been eliminated in the wild, frozen stocks of smallpox virus are still maintained by the governments of the United States and Russia. Disastrous consequences are feared if rogue politicians or terrorists were to get hold of the smallpox strains. Since vaccination programs are now terminated, the world population is more susceptible to smallpox than ever before. 

In Oregon in 1984, followers of the Bhagwan Shree Rajneesh attempted to control a local election by incapacitating the local population. This was done by infecting salad bars in 11 restaurants, produce in grocery stores, doorknobs, and other public domains with Salmonella typhimurium bacteria in the city of The Dalles, Oregon. The attack infected 751 people with severe food poisoning. There were no fatalities. This incident was the first known bioterrorist attack in the United States in the 20th century. It was also the single largest bioterrorism attack on U.S. soil.

In June 1993, the religious group Aum Shinrikyo released anthrax in Tokyo. Eyewitnesses reported a foul odor. The attack was a total failure, infecting not a single person. The reason for this is that the group used the vaccine strain of the bacterium. The spores recovered from the attack showed that they were identical to an anthrax vaccine strain given to animals at the time. These vaccine strains are missing the genes that cause a symptomatic response.

In September and October 2001, several cases of anthrax broke out in the United States, apparently caused deliberately. Letters laced with infectious anthrax were concurrently delivered to news media offices and the U.S Congress, alongside an ambiguously related case in Chile. The letters killed 5.

Types of agents

Under current United States law, bio-agents which have been declared by the U.S. Department of Health and Human Services or the U.S. Department of Agriculture to have the "potential to pose a severe threat to public health and safety" are officially defined as "select agents." The CDC categorizes these agents (A, B or C) and administers the Select Agent Program, which regulates the laboratories which may possess, use, or transfer select agents within the United States. As with US attempts to categorize harmful recreational drugs, designer viruses are not yet categorized and avian H5N1 has been shown to achieve high mortality and human-communication in a laboratory setting.

Category A

These high-priority agents pose a risk to national security, can be easily transmitted and disseminated, result in high mortality, have potential major public health impact, may cause public panic, or require special action for public health preparedness.
Tularemia or "rabbit fever"
Tularemia has a very low fatality rate if treated, but can severely incapacitate. The disease is caused by the Francisella tularensis bacterium, and can be contracted through contact with fur, inhalation, ingestion of contaminated water or insect bites. Francisella tularensis is very infectious. A small number of organisms (10–50 or so) can cause disease. If F. tularensis were used as a weapon, the bacteria would likely be made airborne for exposure by inhalation. People who inhale an infectious aerosol would generally experience severe respiratory illness, including life-threatening pneumonia and systemic infection, if they are not treated. The bacteria that cause tularemia occur widely in nature and could be isolated and grown in quantity in a laboratory, although manufacturing an effective aerosol weapon would require considerable sophistication.
Anthrax
Anthrax is a non-contagious disease caused by the spore-forming bacterium Bacillus anthracis. The ability of Anthrax to produce within small spores, or bacilli bacterium, makes it readily permeable to porous skin and can cause abrupt symptoms within 24 hours of exposure. The dispersal of this pathogen among densely populated areas is said to carry less than one percent mortality rate, for cutaneous exposure, to a ninety percent or higher mortality for untreated inhalational infections. An anthrax vaccine does exist but requires many injections for stable use. When discovered early, anthrax can be cured by administering antibiotics (such as ciprofloxacin). Its first modern incidence in biological warfare were when Scandinavian "freedom fighters" supplied by the German General Staff used anthrax with unknown results against the Imperial Russian Army in Finland in 1916. In 1993, the Aum Shinrikyo used anthrax in an unsuccessful attempt in Tokyo with zero fatalities. Anthrax was used in a series of attacks by a microbiologist at the US Army Medical Research Institute of Infection Disease on the offices of several United States Senators in late 2001. The anthrax was in a powder form and it was delivered by the mail. This bioterrorist attack inevitably prompted seven cases of cutaneous anthrax and eleven cases of inhalation anthrax, with five leading to deaths. Additionally, an estimated 10 to 26 cases had prevented fatality through treatment supplied to over 30,000 individuals. Anthrax is one of the few biological agents that federal employees have been vaccinated for. In the US an anthrax vaccine, Anthrax Vaccine Adsorbed (AVA) exists and requires five injections for stable use. Other anthrax vaccines also exist. The strain used in the 2001 anthrax attack was identical to the strain used by the USAMRIID.
Smallpox
Smallpox is a highly contagious virus. It is transmitted easily through the atmosphere and has a high mortality rate (20–40%). Smallpox was eradicated in the world in the 1970s, thanks to a worldwide vaccination program. However, some virus samples are still available in Russian and American laboratories. Some believe that after the collapse of the Soviet Union, cultures of smallpox have become available in other countries. Although people born pre-1970 will have been vaccinated for smallpox under the WHO program, the effectiveness of vaccination is limited since the vaccine provides high level of immunity for only 3 to 5 years. Revaccination's protection lasts longer. As a biological weapon smallpox is dangerous because of the highly contagious nature of both the infected and their pox. Also, the infrequency with which vaccines are administered among the general population since the eradication of the disease would leave most people unprotected in the event of an outbreak. Smallpox occurs only in humans, and has no external hosts or vectors.
Botulinum toxin
The neurotoxin Botulinum is one of the deadliest toxins known, and is produced by the bacterium Clostridium botulinum. Botulism causes death by respiratory failure and paralysis. Furthermore, the toxin is readily available worldwide due to its cosmetic applications in injections.
Bubonic plague
Plague is a disease caused by the Yersinia pestis bacterium. Rodents are the normal host of plague, and the disease is transmitted to humans by flea bites and occasionally by aerosol in the form of pneumonic plague. The disease has a history of use in biological warfare dating back many centuries, and is considered a threat due to its ease of culture and ability to remain in circulation among local rodents for a long period of time. The weaponized threat comes mainly in the form of pneumonic plague (infection by inhalation) It was the disease that caused the Black Death in Medieval Europe.
Viral hemorrhagic fevers
This includes hemorrhagic fevers caused by members of the family Filoviridae (Marburg virus and Ebola virus), and by the family Arenaviridae (for example Lassa virus and Machupo virus). Ebola virus disease, in particular, has caused high fatality rates ranging from 25–90% with a 50% average. No cure currently exists, although vaccines are in development. The Soviet Union investigated the use of filoviruses for biological warfare, and the Aum Shinrikyo group unsuccessfully attempted to obtain cultures of Ebola virus. Death from Ebola virus disease is commonly due to multiple organ failure and hypovolemic shock. Marburg virus was first discovered in Marburg, Germany. No treatments currently exist aside from supportive care. The arenaviruses have a somewhat reduced case-fatality rate compared to disease caused by filoviruses, but are more widely distributed, chiefly in central Africa and South America.

Category B

Category B agents are moderately easy to disseminate and have low mortality rates.

Category C

Category C agents are emerging pathogens that might be engineered for mass dissemination because of their availability, ease of production and dissemination, high mortality rate, or ability to cause a major health impact.

Planning and response

Planning may involve the development of biological identification systems. Until recently in the United States, most biological defense strategies have been geared to protecting soldiers on the battlefield rather than ordinary people in cities. Financial cutbacks have limited the tracking of disease outbreaks. Some outbreaks, such as food poisoning due to E. coli or Salmonella, could be of either natural or deliberate origin.

Preparedness

Biological agents are relatively easy to obtain by terrorists and are becoming more threatening in the U.S., and laboratories are working on advanced detection systems to provide early warning, identify contaminated areas and populations at risk, and to facilitate prompt treatment. Methods for predicting the use of biological agents in urban areas as well as assessing the area for the hazards associated with a biological attack are being established in major cities. In addition, forensic technologies are working on identifying biological agents, their geographical origins and/or their initial source. Efforts include decontamination technologies to restore facilities without causing additional environmental concerns. 

Early detection and rapid response to bioterrorism depend on close cooperation between public health authorities and law enforcement; however, such cooperation is currently lacking. National detection assets and vaccine stockpiles are not useful if local and state officials do not have access to them.

Aspects of protection against bioterrorism in the United States include,
  • Detection and resilience strategies in combating bioterrorism. This occurs primarily through the efforts of the Office of Health Affairs (OHA), a part of the Department of Homeland Security (DHS), whose role is to prepare for an emergency situation that impacts the health of the American populace. Detection has two primary technological factors. First there is OHA's BioWatch program in which collection devices are disseminated to thirty high risk areas throughout the country to detect the presence of aerosolized biological agents before symptoms present in patients. This is significant primarily because it allows a more proactive response to a disease outbreak rather than the more passive treatment of the past.
  • Implementation of the Generation-3 automated detection system. This advancement is significant simply because it enables action to be taken in four to six hours due to its automatic response system, whereas the previous system required aerosol detectors to be manually transported to laboratories. Resilience is a multifaceted issue as well, as addressed by OHA. One way in which this is ensured is through exercises that establish preparedness; programs like the Anthrax Response Exercise Series exist to ensure that, regardless of the incident, all emergency personnel will be aware of the role they must fill. Moreover, by providing information and education to public leaders, emergency medical services and all employees of the DHS, OHS suggests it can significantly decrease the impact of bioterrorism.
  • Enhancing the technological capabilities of first responders is accomplished through numerous strategies. The first of these strategies was developed by the Science and Technology Directorate (S&T) of DHS to ensure that the danger of suspicious powders could be effectively assessed, (as many dangerous biological agents such as anthrax exist as a white powder). By testing the accuracy and specificity of commercially available systems used by first responders, the hope is that all biologically harmful powders can be rendered ineffective.
  • Enhanced equipment for first responders. One recent advancement is the commercialization of a new form of Tyvex™ armor which protects first responders and patients from chemical and biological contaminants. There has also been a new generation of Self-Contained Breathing Apparatuses (SCBA) which has been recently made more robust against bioterrorism agents. All of these technologies combine to form what seems like a relatively strong deterrent to bioterrorism. However, New York City as an entity has numerous organizations and strategies that effectively serve to deter and respond to bioterrorism as it comes. From here the logical progression is into the realm of New York City’s specific strategies to prevent bioterrorism.
  • Excelsior Challenge. In the second week of September 2016, the state of New York held a large emergency response training exercise called the Excelsior Challenge, with over 100 emergency responders participating. According to WKTV, "This is the fourth year of the Excelsior Challenge, a training exercise designed for police and first responders to become familiar with techniques and practices should a real incident occur." The event was held over three days and hosted by the State Preparedness Training Center in Oriskany, New York. Participants included bomb squads, canine handlers, tactical team officers and emergency medical services. In an interview with Homeland Preparedness News, Bob Stallman, assistant director at the New York State Preparedness Training Center, said, “We’re constantly seeing what’s happening around the world and we tailor our training courses and events for those types of real-world events.” For the first time, the 2016 training program implemented New York’s new electronic system. The system, called NY Responds, electronically connects every county in New York to aid in disaster response and recovery. As a result, "counties have access to a new technology known as Mutualink, which improves interoperability by integrating telephone, radio, video, and file-sharing into one application to allow local emergency staff to share real-time information with the state and other counties." The State Preparedness Training Center in Oriskany was designed by the State Division of Homeland Security, and Emergency Services (DHSES) in 2006. It cost $42 million to construct on over 1100 acres and is available for training 360 days a year. Students from SUNY Albany's College of Emergency Preparedness, Homeland Security and Cybersecurity, were able to participate in this year's exercise and learn how "DHSES supports law enforcement specialty teams."
  • Project BioShield The accrual of vaccines and treatments for potential biological threats, also known as medical countermeasures has been an important aspect in preparing for a potential bioterrorist attack; this took the form of a program beginning in 2004, referred to as Project BioShield. The significance of this program should not be overlooked as “there is currently enough smallpox vaccine to inoculate every United States citizen… and a variety of therapeutic drugs to treat the infected.” The Department of Defense also has a variety of laboratories currently working to increase the quantity and efficacy of countermeasures that comprise the national stockpile. Efforts have also been taken to ensure that these medical countermeasures can be disseminated effectively in the event of a bioterrorist attack. The National Association of Chain Drug Stores championed this cause by encouraging the participation of the private sector in improving the distribution of such countermeasures if required.
On a CNN news broadcast in 2011, the CNN chief medical correspondent, Dr. Sanjay Gupta, weighed in on the American government’s recent approach to bioterrorist threats. He explains how, even though the United States would be better fending off bioterrorist attacks now than they would be a decade ago, the amount of money available to fight bioterrorism over the last three years has begun to decrease. Looking at a detailed report that examined the funding decrease for bioterrorism in fifty-one American cities, Dr. Gupta stated that the cities “wouldn’t be able to distribute vaccines as well” and “wouldn’t be able to track viruses”. He went on to say that movie portrayals of global pandemics, such as Contagion, were actually quite possible and may occur in the United States under the right conditions.

A news broadcast by MSNBC in 2010 also stressed the low levels of bioterrorism preparedness in the United States. The broadcast stated that a bipartisan report gave the Obama administration a failing grade for its efforts to respond to a bioterrorist attack. The news broadcast invited the former New York City police commissioner, Howard Safir, to explain how the government would fare in combating such an attack. He said how “biological and chemical weapons are probable and relatively easy to disperse”. Furthermore, Safir thought that efficiency in bioterrorism preparedness is not necessarily a question of money, but is instead dependent on putting resources in the right places. The broadcast suggested that the nation was not ready for something more serious.

In a September 2016 interview conducted by Homeland Preparedness News, Daniel Gerstein, a senior policy researcher for the RAND Corporation, stresses the importance in preparing for potential bioterrorist attacks on the nation. He implored the U.S. government to take the proper and necessary actions to implement a strategic plan of action to save as many lives as possible and to safeguard against potential chaos and confusion. He believes that because there have been no significant instances of bioterrorism since the anthrax attacks in 2001, the government has allowed itself to become complacent making the country that much more vulnerable to unsuspecting attacks, thereby further endangering the lives of U.S. citizens.

Gerstein formerly served in the Science and Technology Directorate of the Department of Homeland Security from 2011 to 2014. He claims there has not been a serious plan of action since 2004 during George W. Bush's presidency, in which he issued a Homeland Security directive delegating responsibilities among various federal agencies. He also stated that the blatant mishandling of the Ebola virus outbreak in 2014 attested to the government's lack of preparation. This past May, legislation that would create a national defense strategy was introduced in the Senate, coinciding with the timing of ISIS-affiliated terrorist groups get closer to weaponizing biological agents. Last August, Kenyan officials apprehended two members of an Islamic extremist group in motion to set off a biological bomb containing anthrax. Mohammed Abdi Ali, the believed leader of the group, who was a medical intern, was arrested along with his wife, a medical student. The two were caught just before carrying out their plan. The Blue Ribbon Study Panel on Biodefense, which comprises a group of experts on national security and government officials, in which Gerstein had previously testified to, submitted its National Blueprint for Biodefense to Congress in October 2015 listing their recommendations for devising an effective plan.

Bill Gates said in a February 18 Business Insider op-ed (published near the time of his Munich Security Conference speech) that it is possible for an airborne pathogen to kill at least 30 million people over the course of a year. In a New York Times report, the Gates Foundation predicted that a modern outbreak similar to the Spanish Influenza pandemic (which killed between 50 million and 100 million people) could end up killing more than 360 million people worldwide, even considering widespread availability of vaccines and other healthcare tools. The report cited increased globalization, rapid international air travel, and urbanization as increased reasons for concern. In a March 9, 2017 interview with CNBC, former U.S. Senator Joe Lieberman, who was co-chair of the bipartisan Blue Ribbon Study Panel on Biodefense, said a worldwide pandemic could end the lives of more people than a nuclear war. Lieberman also expressed worry that a terrorist group like ISIS could develop a synthetic influenza strain and introduce it to the world to kill civilians. In July 2017, Robert C. Hutchinson, former agent at the Department of Homeland Security, called for a "whole-of-government" response to the next global health threat, which he described as including strict security procedures at our borders and proper execution of government preparedness plans.

Also, novel approaches in biotechnology, such as synthetic biology, could be used in the future to design new types of biological warfare agents. Special attention has to be laid on future experiments (of concern) that:
  • Would demonstrate how to render a vaccine ineffective;
  • Would confer resistance to therapeutically useful antibiotics or antiviral agents;
  • Would enhance the virulence of a pathogen or render a nonpathogen virulent;
  • Would increase transmissibility of a pathogen;
  • Would alter the host range of a pathogen;
  • Would enable the evasion of diagnostic/detection tools;
  • Would enable the weaponization of a biological agent or toxin
Most of the biosecurity concerns in synthetic biology, however, are focused on the role of DNA synthesis and the risk of producing genetic material of lethal viruses (e.g. 1918 Spanish flu, polio) in the lab. Recently, the CRISPR/Cas system has emerged as a promising technique for gene editing. It was hailed by The Washington Post as "the most important innovation in the synthetic biology space in nearly 30 years." While other methods take months or years to edit gene sequences, CRISPR speeds that time up to weeks. However, due to its ease of use and accessibility, it has raised a number of ethical concerns, especially surrounding its use in the biohacking space.

Biosurveillance

In 1999, the University of Pittsburgh's Center for Biomedical Informatics deployed the first automated bioterrorism detection system, called RODS (Real-Time Outbreak Disease Surveillance). RODS is designed to draw collect data from many data sources and use them to perform signal detection, that is, to detect a possible bioterrorism event at the earliest possible moment. RODS, and other systems like it, collect data from sources including clinic data, laboratory data, and data from over-the-counter drug sales. In 2000, Michael Wagner, the codirector of the RODS laboratory, and Ron Aryel, a subcontractor, conceived the idea of obtaining live data feeds from "non-traditional" (non-health-care) data sources. The RODS laboratory's first efforts eventually led to the establishment of the National Retail Data Monitor, a system which collects data from 20,000 retail locations nationwide.

On February 5, 2002, George W. Bush visited the RODS laboratory and used it as a model for a $300 million spending proposal to equip all 50 states with biosurveillance systems. In a speech delivered at the nearby Masonic temple, Bush compared the RODS system to a modern "DEW" line (referring to the Cold War ballistic missile early warning system).

The principles and practices of biosurveillance, a new interdisciplinary science, were defined and described in the Handbook of Biosurveillance, edited by Michael Wagner, Andrew Moore and Ron Aryel, and published in 2006. Biosurveillance is the science of real-time disease outbreak detection. Its principles apply to both natural and man-made epidemics (bioterrorism). 

Data which potentially could assist in early detection of a bioterrorism event include many categories of information. Health-related data such as that from hospital computer systems, clinical laboratories, electronic health record systems, medical examiner record-keeping systems, 911 call center computers, and veterinary medical record systems could be of help; researchers are also considering the utility of data generated by ranching and feedlot operations, food processors, drinking water systems, school attendance recording, and physiologic monitors, among others. Intuitively, one would expect systems which collect more than one type of data to be more useful than systems which collect only one type of information (such as single-purpose laboratory or 911 call-center based systems), and be less prone to false alarms, and this appears to be the case.

In Europe, disease surveillance is beginning to be organized on the continent-wide scale needed to track a biological emergency. The system not only monitors infected persons, but attempts to discern the origin of the outbreak. 

Researchers are experimenting with devices to detect the existence of a threat:
  • Tiny electronic chips that would contain living nerve cells to warn of the presence of bacterial toxins (identification of broad range toxins)
  • Fiber-optic tubes lined with antibodies coupled to light-emitting molecules (identification of specific pathogens, such as anthrax, botulinum, ricin)
New research shows that ultraviolet avalanche photodiodes offer the high gain, reliability and robustness needed to detect anthrax and other bioterrorism agents in the air. The fabrication methods and device characteristics were described at the 50th Electronic Materials Conference in Santa Barbara on June 25, 2008. Details of the photodiodes were also published in the February 14, 2008 issue of the journal Electronics Letters and the November 2007 issue of the journal IEEE Photonics Technology Letters.

The United States Department of Defense conducts global biosurveillance through several programs, including the Global Emerging Infections Surveillance and Response System.

Another powerful tool developed within New York City for use in countering bioterrorism is the development of the New York City Syndromic Surveillance System. This system is essentially a way of tracking disease progression throughout New York City, and was developed by the New York City Department of Health and Mental Hygiene (NYC DOHMH) in the wake of the 9/11 attacks. The system works by tracking the symptoms of those taken into the emergency department—based on the location of the hospital to which they are taken and their home address—and assessing any patterns in symptoms. These established trends can then be observed by medical epidemiologists to determine if there are any disease outbreaks in any particular locales; maps of disease prevalence can then be created rather easily. This is an obviously beneficial tool in fighting bioterrorism as it provides a means through which such attacks could be discovered in their nascence; assuming bioterrorist attacks result in similar symptoms across the board, this strategy allows New York City to respond immediately to any bioterrorist threats that they may face with some level of alacrity.

Response to bioterrorism incident or threat

Government agencies which would be called on to respond to a bioterrorism incident would include law enforcement, hazardous materials/decontamination units and emergency medical units, if they exist. 

The US military has specialized units, which can respond to a bioterrorism event; among them are the United States Marine Corps' Chemical Biological Incident Response Force and the U.S. Army's 20th Support Command (CBRNE), which can detect, identify, and neutralize threats, and decontaminate victims exposed to bioterror agents. US response would include the Center for Disease Control

Historically, governments and authorities have relied on quarantines to protect their populations. International bodies such as the World Health Organization already devote some of their resources to monitoring epidemics and have served clearing-house roles in historical epidemics. 

Media attention toward the seriousness of biological attacks increased in 2013-2014. In July 2013, Forbes published an article with the title "Bioterrorism: A Dirty Little Threat With Huge Potential Consequences." In November 2013, Fox News reported on a new strain of botulism, saying that the Centers for Disease and Control lists botulism as one of two agents that have “the highest risks of mortality and morbidity”, noting that there is no antidote for botulism. USA Today reported that the U.S. military in November was trying to develop a vaccine for troops from the bacteria that cause the disease Q fever, an agent the military once used as a biological weapon. In February 2014, the former special assistant and senior director for biodefense policy to President George W. Bush called the bioterrorism risk imminent and uncertain and Congressman Bill Pascrell called for increasing federal measures against bioterrorism as a “matter of life or death.” The New York Times wrote a story saying the United States would spend $40 million to help certain low and middle-income countries deal with the threats of bioterrorism and infectious diseases.

Bill Gates has warned that bioterrorism could kill more people than nuclear war.

In February 2018, a CNN employee discovered on an airplane a “sensitive, top-secret document in the seatback pouch explaining how the Department of Homeland Security would respond to a bioterrorism attack at the Super Bowl.”

2017 U.S. budget proposal affecting bioterrorism programs

President Donald Trump promoted his first budget around keeping America safe. However, one aspect of defense would receive less money: "protecting the nation from deadly pathogens, man-made or natural," according to the New York Times. Agencies tasked with biosecurity get a decrease in funding under the Administration's budget proposal. 

For example:
“The next weapon of mass destruction may not be a bomb," Lawrence O. Gostin, the director of the World Health Organization’s Collaborating Center on Public Health Law and Human Rights, told the New York Times. “It may be a tiny pathogen that you can’t see, smell or taste, and by the time we discover it, it’ll be too late."

Lack of international standards on public health experiments

Dr. Tom Inglesy, the CEO and director of the Center for Health Security at the Johns Hopkins Bloomberg School of Public Health and an internationally recognized expert on public health preparedness, pandemic and emerging infectious disease said in 2017 that the lack of an internationally standardized approval process that could be used to guide countries in conducting public health experiments for resurrecting a disease that's already been eradicated increases the risk that the disease could be used in bioterrorism. He was referring to the lab synthesis of horsepox in 2017 by researchers at the University of Alberta. Those researchers recreated horsepox, an extinct cousin of the smallpox virus, in order to research new ways to treat cancer.

Thermodynamic diagrams

From Wikipedia, the free encyclopedia https://en.wikipedia.org/wiki/Thermodynamic_diagrams Thermodynamic diagrams are diagrams used to repr...