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Materialism is a form of philosophical monism which holds that matter is the fundamental substance in nature, and that all things, including mental aspects and consciousness, are results of material interactions.

In Idealism, mind and consciousness are first-order realities to which matter is subject and secondary. In philosophical materialism the converse is true. Here mind and consciousness are by-products or epiphenomena of material processes (the biochemistry of the human brain and nervous system, for example) without which they cannot exist. According to this doctrine the material creates and determines consciousness, not vice versa. Materialists believe that Matter and the physical laws that govern it constitute the most reliable guide to the nature of mind and consciousness.

Materialist theories are mainly divided into three groups. Naive materialism identifies the material world with specific elements (e.g. the scheme of the four elements—fire, air, water and earth—devised by the Pre-Socratic philosopher Empedocles). Metaphysical materialism examines separated parts of the world in a static, isolated environment. Dialectical materialism adapts the Hegelian dialectic for materialism, examining parts of the world in relation to each other within a dynamic environment.

Materialism is closely related to physicalism, the view that all that exists is ultimately physical. Philosophical physicalism has evolved from materialism with the discoveries of the physical sciences to incorporate more sophisticated notions of physicality than mere ordinary matter, such as: spacetime, physical energies and forces, dark matter, and so on. Thus the term "physicalism" is preferred over "materialism" by some, while others use the terms as if they are synonymous.

Philosophies contradictory to materialism or physicalism include idealism, pluralism, dualism, and other forms of monism.

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