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Morphine
Morphin - Morphine.svg
Morphine-from-xtal-3D-balls.png
Clinical data
Pronunciation/ˈmrfn/
Trade namesStatex, MSContin, Oramorph, Sevredol, and others
AHFS/Drugs.comMonograph
Pregnancy
category
  • AU: C
Dependence
liability
High
Addiction
liability
High
Routes of
administration
Inhalation (smoking), insufflation (snorting), by mouth (PO), rectal, subcutaneous (SC), intramuscular (IM), intravenous (IV), epidural, and intrathecal (IT)
Drug classopioid
ATC code
Legal status
Legal status
Pharmacokinetic data
Bioavailability20–40% (by mouth), 36–71% (rectally), 100% (IV/IM)
Protein binding30–40%
MetabolismHepatic 90%
Onset of action5 minutes (IV), 15 minutes (IM), 20 minutes (PO)
Elimination half-life2–3 hours
Duration of action3–7 hours
ExcretionRenal 90%, biliary 10%
Identifiers